Works matching AU Brabec, Viktor
Results: 107
Multitargeting Prodrugs that Release Oxaliplatin, Doxorubicin and Gemcitabine are Potent Inhibitors of Tumor Growth and Effective Inducers of Immunogenic Cell Death.
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- Angewandte Chemie, 2023, v. 135, n. 42, p. 1, doi. 10.1002/ange.202310774
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- Publication type:
- Article
On the Biology of Werner's Complex.
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- Angewandte Chemie, 2021, v. 133, n. 31, p. 17260, doi. 10.1002/ange.202105019
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- Publication type:
- Article
A Multi‐action Pt<sup>IV</sup> Conjugate with Oleate and Cinnamate Ligands Targets Human Epithelial Growth Factor Receptor HER2 in Aggressive Breast Cancer Cells.
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- Angewandte Chemie, 2020, v. 132, n. 47, p. 21343, doi. 10.1002/ange.202009491
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- Publication type:
- Article
Glycoconjugated Metallohelices have Improved Nuclear Delivery and Suppress Tumour Growth In Vivo.
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- Angewandte Chemie, 2020, v. 132, n. 34, p. 14785, doi. 10.1002/ange.202006814
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- Publication type:
- Article
Platinum (IV) Derivatives with Cinnamate Axial Ligands as Potent Agents Against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells.
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- Angewandte Chemie, 2020, v. 132, n. 8, p. 3355, doi. 10.1002/ange.201913996
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- Publication type:
- Article
Towards Novel Photodynamic Anticancer Agents Generating Superoxide Anion Radicals: A Cyclometalated Ir<sup>III</sup> Complex Conjugated to a Far‐Red Emitting Coumarin.
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- Angewandte Chemie, 2019, v. 131, n. 19, p. 6377, doi. 10.1002/ange.201901268
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- Publication type:
- Article
Study of thermal and acid denaturation of DNA by means of voltammetry at graphite electrodes.
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- Biopolymers, 1979, v. 18, n. 10, p. 2397, doi. 10.1002/bip.1979.360181003
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- Publication type:
- Article
Asymmetric triplex metallohelices stabilise DNA G-quadruplexes in promoter oncogene sequences and efficiently reduce their expression in cancer cells.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2198678
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- Article
In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 877, doi. 10.1080/14756366.2019.1593159
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- Publication type:
- Article
Double-check probing of DNA bending and unwinding by XPA-RPA: an architectural function in DNA repair.
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- EMBO Journal, 2001, v. 20, n. 13, p. 3554, doi. 10.1093/emboj/20.13.3554
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- Publication type:
- Article
Toxicity in tumor cells, DNA binding mode, and resistance to decomposition by sulfur nucleophiles of new dinuclear bifunctional trans-Pt<sup>II</sup> complexes containing long alkane linkers.
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- Pure & Applied Chemistry, 2013, v. 85, n. 2, p. 343, doi. 10.1351/PAC-CON-12-07-08
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- Publication type:
- Article
An anticancer Os(II) bathophenanthroline complex as a human breast cancer stem cell-selective, mammosphere potent agent that kills cells by necroptosis.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49774-x
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- Publication type:
- Article
Biochemical Studies of the Thermal Effects on DNA Modifications by the Antitumor Cisplatin and Their Repair.
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- ChemBioChem, 2007, v. 8, n. 16, p. 2008, doi. 10.1002/cbic.200700288
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- Publication type:
- Article
DNA adducts of antitumor cisplatin preclude telomeric sequences from forming G quadruplexes.
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- Journal of Biological Inorganic Chemistry (JBIC), 2009, v. 14, n. 6, p. 959, doi. 10.1007/s00775-009-0508-6
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- Publication type:
- Article
DNA and glutathione interactions in cell-free media of asymmetric platinum(II) complexes cis- and trans-[PtCl<sub>2</sub>(isopropylamine)(1-methylimidazole)]: relations to their different antitumor effects.
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- Journal of Biological Inorganic Chemistry (JBIC), 2009, v. 14, n. 1, p. 75, doi. 10.1007/s00775-008-0425-0
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- Publication type:
- Article
Binding of mismatch repair protein MutS to mispaired DNA adducts of intercalating ruthenium(II) arene complexes.
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- Journal of Biological Inorganic Chemistry (JBIC), 2008, v. 13, n. 6, p. 993, doi. 10.1007/s00775-008-0386-3
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- Publication type:
- Article
NMR analysis of duplex d(CGCGATCGCG)<sub>2</sub> modified by Λ- and Δ-[Ru(bpy)<sub>2</sub>(m-GHK)]Cl<sub>2</sub> and DNA photocleavage study.
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- Journal of Biological Inorganic Chemistry (JBIC), 2007, v. 12, n. 3, p. 279, doi. 10.1007/s00775-006-0184-8
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- Publication type:
- Article
NMR analysis of duplex d(CGCGATCGCG)<sub>2</sub> modified by Λ- and Δ-[Ru(bpy)<sub>2</sub>(m-GHK)]Cl<sub>2</sub> and DNA photocleavage study.
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- 2007
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- Publication type:
- Correction Notice
Structural characterization and DNA interactions of new cytotoxic transplatin analogues containing one planar and one nonplanar heterocyclic amine ligand.
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- Journal of Biological Inorganic Chemistry (JBIC), 2005, v. 10, n. 7, p. 722, doi. 10.1007/s00775-005-0024-2
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- Publication type:
- Article
Formation of platinated GG cross-links on DNA by photoactivation of a platinum(IV) azide complex.
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- Journal of Biological Inorganic Chemistry (JBIC), 2003, v. 8, n. 7, p. 741
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- Publication type:
- Article
The Thermodynamics of Translesion DNA Synthesis Past Major Adducts of Enantiomeric Analogues of Antitumor Cisplatin.
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- Chemistry - An Asian Journal, 2012, v. 7, n. 5, p. 1026, doi. 10.1002/asia.201100886
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- Publication type:
- Article
DNA Interstrand Cross-Links of an Antitumor Trinuclear Platinum(II) Complex: Thermodynamic Analysis and Chemical Probing.
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- Chemistry - An Asian Journal, 2011, v. 6, n. 6, p. 1566, doi. 10.1002/asia.201000935
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- Publication type:
- Article
Gallium(III) Complex with Cloxyquin Ligands Induces Ferroptosis in Cancer Cells and Is a Potent Agent against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells.
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- Bioinorganic Chemistry & Applications, 2022, p. 1, doi. 10.1155/2022/3095749
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- Publication type:
- Article
Probing the Thermodynamics of Incorporation of N<sup>6</sup>‐methyl‐dATP Opposite an Abasic Site, dCMP, and dTMP During Simulated DNA Synthesis by Differential Scanning Calorimetry.
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- ChemistrySelect, 2018, v. 3, n. 46, p. 13076, doi. 10.1002/slct.201803565
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- Publication type:
- Article
Different affinity of nuclear factor-kappa B proteins to DNA modified by antitumor cisplatin and its clinically ineffective trans isomer.
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- FEBS Journal, 2014, v. 281, n. 5, p. 1393, doi. 10.1111/febs.12711
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- Publication type:
- Article
Recognition of DNA bulges by dinuclear iron( II) metallosupramolecular helicates.
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- 2014
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- Publication type:
- Editorial
The mechanism of antiproliferative activity of the oxaliplatin pyrophosphate derivative involves its binding to nuclear DNA in cancer cells.
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- Journal of Biological Inorganic Chemistry (JBIC), 2023, v. 28, n. 7, p. 669, doi. 10.1007/s00775-023-02017-x
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- Publication type:
- Article
Synthesis, antiproliferative activity in cancer cells and DNA interaction studies of [Pt(cis-1,3-diaminocycloalkane)Cl<sub>2</sub>] analogs.
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- Journal of Biological Inorganic Chemistry (JBIC), 2020, v. 25, n. 6, p. 913, doi. 10.1007/s00775-020-01809-9
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- Publication type:
- Article
Antiproliferative, DNA binding, and cleavage properties of dinuclear Co(III) complexes containing the bioactive quinizarin ligand.
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- Journal of Biological Inorganic Chemistry (JBIC), 2020, v. 25, n. 2, p. 339, doi. 10.1007/s00775-020-01765-4
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- Publication type:
- Article
A new 4-(pyridinyl)-4H-benzo[g]chromene-5,10-dione ruthenium(II) complex inducing senescence in 518A2 melanoma cells.
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- Journal of Biological Inorganic Chemistry (JBIC), 2019, v. 24, n. 5, p. 647, doi. 10.1007/s00775-019-01677-y
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- Publication type:
- Article
The stability of DNA intrastrand cross-links of antitumor transplatin derivative containing non-bulky methylamine ligands.
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- Journal of Biological Inorganic Chemistry (JBIC), 2014, v. 19, n. 7, p. 1203, doi. 10.1007/s00775-014-1176-8
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- Publication type:
- Article
Insight into the toxic effects of cis-dichloridoplatinum(II) complexes containing 7-azaindole halogeno derivatives in tumor cells.
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- Journal of Biological Inorganic Chemistry (JBIC), 2013, v. 18, n. 5, p. 579, doi. 10.1007/s00775-013-1003-7
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- Publication type:
- Article
Bipyrimidine ruthenium(II) arene complexes: structure, reactivity and cytotoxicity.
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- Journal of Biological Inorganic Chemistry (JBIC), 2012, v. 17, n. 7, p. 1033, doi. 10.1007/s00775-012-0917-9
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- Publication type:
- Article
Antitumor carboplatin is more toxic in tumor cells when photoactivated: enhanced DNA binding.
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- Journal of Biological Inorganic Chemistry (JBIC), 2012, v. 17, n. 6, p. 891, doi. 10.1007/s00775-012-0906-z
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- Publication type:
- Article
Thermodynamic stability and energetics of DNA duplexes containing major intrastrand cross-links of second-generation antitumor dinuclear Pt complexes.
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- Journal of Biological Inorganic Chemistry (JBIC), 2012, v. 17, n. 2, p. 187, doi. 10.1007/s00775-011-0841-4
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- Publication type:
- Article
Antitumor bifunctional dinuclear Pt complex BBR3535 forms interduplex DNA cross-links under molecular crowding conditions.
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- Journal of Biological Inorganic Chemistry (JBIC), 2012, v. 17, n. 2, p. 239, doi. 10.1007/s00775-011-0845-0
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- Publication type:
- Article
ON THE POSSIBLE INTERACTION OF PLATINUM CHEMOTHERAPEUTICS WITH HUMAN LIVER MICROSOMAL CYTOCHROMES P450.
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- 2007
- By:
- Publication type:
- Abstract
Multitargeting Prodrugs that Release Oxaliplatin, Doxorubicin and Gemcitabine are Potent Inhibitors of Tumor Growth and Effective Inducers of Immunogenic Cell Death.
- Published in:
- Angewandte Chemie International Edition, 2023, v. 62, n. 42, p. 1, doi. 10.1002/anie.202310774
- By:
- Publication type:
- Article
On the Biology of Werner's Complex.
- Published in:
- Angewandte Chemie International Edition, 2021, v. 60, n. 31, p. 17123, doi. 10.1002/anie.202105019
- By:
- Publication type:
- Article
A Multi‐action Pt<sup>IV</sup> Conjugate with Oleate and Cinnamate Ligands Targets Human Epithelial Growth Factor Receptor HER2 in Aggressive Breast Cancer Cells.
- Published in:
- Angewandte Chemie International Edition, 2020, v. 59, n. 47, p. 21157, doi. 10.1002/anie.202009491
- By:
- Publication type:
- Article
Glycoconjugated Metallohelices have Improved Nuclear Delivery and Suppress Tumour Growth In Vivo.
- Published in:
- Angewandte Chemie International Edition, 2020, v. 59, n. 34, p. 14677, doi. 10.1002/anie.202006814
- By:
- Publication type:
- Article
Platinum (IV) Derivatives with Cinnamate Axial Ligands as Potent Agents Against Both Differentiated and Tumorigenic Cancer Stem Rhabdomyosarcoma Cells.
- Published in:
- Angewandte Chemie International Edition, 2020, v. 59, n. 8, p. 3329, doi. 10.1002/anie.201913996
- By:
- Publication type:
- Article
Towards Novel Photodynamic Anticancer Agents Generating Superoxide Anion Radicals: A Cyclometalated Ir<sup>III</sup> Complex Conjugated to a Far‐Red Emitting Coumarin.
- Published in:
- Angewandte Chemie International Edition, 2019, v. 58, n. 19, p. 6311, doi. 10.1002/anie.201901268
- By:
- Publication type:
- Article
Substitution‐Inert Polynuclear Platinum Complexes That Inhibit the Activity of DNA Polymerase in Triplex‐Forming Templates.
- Published in:
- Angewandte Chemie International Edition, 2018, v. 57, n. 28, p. 8535, doi. 10.1002/anie.201803448
- By:
- Publication type:
- Article
Iron(II) supramolecular helicates interfere with the HIV-1 Tat-TAR RNA interaction critical for viral replication.
- Published in:
- Scientific Reports, 2016, p. 29674, doi. 10.1038/srep29674
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- Publication type:
- Article
Processing and Bypass of a Site-Specific DNA Adduct of the Cytotoxic Platinum–Acridinylthiourea Conjugate by Polymerases Involved in DNA Repair: Biochemical and Thermodynamic Aspects.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10838, doi. 10.3390/ijms221910838
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- Publication type:
- Article
Genomic Tackling of Human Satellite DNA: Breaking Barriers through Time.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4707, doi. 10.3390/ijms22094707
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- Publication type:
- Article
Thermodynamic Insights by Microscale Thermophoresis into Translesion DNA Synthesis Catalyzed by DNA Polymerases Across a Lesion of Antitumor Platinum–Acridine Complex.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7806, doi. 10.3390/ijms21207806
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- Publication type:
- Article
Translesion DNA Synthesis Across Lesions Induced by Oxidative Products of Pyrimidines: An Insight into the Mechanism by Microscale Thermophoresis.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 20, p. 5012, doi. 10.3390/ijms20205012
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- Publication type:
- Article
Palladium and Platinum Complexes of the Antimetabolite Fludarabine with Vastly Enhanced Selectivity for Tumour over Non-Malignant Cells.
- Published in:
- Molecules, 2023, v. 28, n. 13, p. 5173, doi. 10.3390/molecules28135173
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- Publication type:
- Article