OpenURL Connection Search

Select item for more details and to access through your institution.

The performance of metabolomics-based prediction scores for mortality in older patients with solid tumors.
Published in:
GeroScience, 2024, v. 46, n. 6, p. 5615, doi. 10.1007/s11357-024-01261-6
By:
- van Holstein, Yara;
- Mooijaart, Simon P.;
- van Oevelen, Mathijs;
- van Deudekom, Floor J.;
- Vojinovic, Dina;
- Bizzarri, Daniele;
- van den Akker, Erik B.;
- Noordam, Raymond;
- Deelen, Joris;
- van Heemst, Diana;
- de Glas, Nienke A.;
- Holterhues, Cynthia;
- Labots, Geert;
- van den Bos, Frederiek;
- Beekman, Marian;
- Slagboom, P. Eline;
- van Munster, Barbara C.;
- Portielje, Johanneke E. A.;
- Trompet, Stella
Publication type:
Article
Lifestyle‐Intervention‐Induced Reduction of Abdominal Fat Is Reflected by a Decreased Circulating Glycerol Level and an Increased HDL Diameter.
Published in:
Molecular Nutrition & Food Research, 2020, v. 64, n. 10, p. 1, doi. 10.1002/mnfr.201900818
By:
- Beekman, Marian;
- Schutte, Bianca A.M.;
- Akker, Erik B. van den;
- Noordam, Raymond;
- Dibbets‐Schneider, Petra;
- Geus‐Oei, Lioe‐Fee;
- Deelen, Joris;
- Rest, Ondine van de;
- Heemst, Diana van;
- Feskens, Edith J.M.;
- Slagboom, P. Eline
Publication type:
Article
Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways.
Published in:
Age, 2013, v. 35, n. 1, p. 235, doi. 10.1007/s11357-011-9340-3
By:
- Deelen, Joris;
- Uh, Hae-Won;
- Monajemi, Ramin;
- Heemst, Diana;
- Thijssen, Peter;
- Böhringer, Stefan;
- Akker, Erik;
- Craen, Anton;
- Rivadeneira, Fernando;
- Uitterlinden, André;
- Westendorp, Rudi;
- Goeman, Jelle;
- Slagboom, P.;
- Houwing-Duistermaat, Jeanine;
- Beekman, Marian
Publication type:
Article
Genetics of human longevity: From variants to genes to pathways.
Published in:
Journal of Internal Medicine, 2024, v. 295, n. 4, p. 416, doi. 10.1111/joim.13740
By:
- Smulders, Larissa;
- Deelen, Joris
Publication type:
Article
Distinguishing Between Longevity and Buffered-Deleterious Genotypes for Exceptional Human Longevity: The Case of the MTP Gene.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67, n. 11, p. 1153, doi. 10.1093/gerona/gls103
By:
- Huffman, Derek M.;
- Deelen, Joris;
- Ye, Kenny;
- Bergman, Aviv;
- Slagboom, Eline P.;
- Barzilai, Nir;
- Atzmon, Gil
Publication type:
Article
SO DIFFERENT BUT EQUAL: 33 LONGEVITY GENES' LOCI IN THE ROMA AND IN THE GENERAL POPULATION OF CROATIA.
Published in:
Anthropologie, 2023, v. 61, n. 1, p. 1, doi. 10.26720/anthro.22.04.29.1
By:
- ŠKARIĆ-JURIĆ, TATJANA;
- CELINŠĆAK, ŽELJKA;
- ŠETINC, MAJA;
- BOČKOR, LUKA;
- MARKOVIĆ, ANITA STOJANOVIĆ;
- PETRANOVIĆ, MATEA ZAJC;
- SALIHOVIĆ, MARIJANA PERIČIĆ;
- DEELEN, JORIS;
- JANIĆIJEVIĆ, BRANKA;
- NARANČIĆ, NINA SMOLEJ
Publication type:
Article
Multivariate genomic scan implicates novel loci and haem metabolism in human ageing.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17312-3
By:
- Timmers, Paul R. H. J.;
- Wilson, James F.;
- Joshi, Peter K.;
- Deelen, Joris
Publication type:
Article
Challenges in anti‐aging medicine–trends in biomarker discovery and therapeutic interventions for a healthy lifespan.
Published in:
Journal of Cellular & Molecular Medicine, 2023, v. 27, n. 18, p. 2643, doi. 10.1111/jcmm.17912
By:
- Popescu, Iuliana;
- Deelen, Joris;
- Illario, Maddalena;
- Adams, Jan
Publication type:
Article
Blood lipids influence DNA methylation in circulating cells.
Published in:
Genome Biology, 2016, v. 17, p. 1, doi. 10.1186/s13059-016-1000-6
By:
- Dekkers, Koen F.;
- van Iterson, Maarten;
- Slieker, Roderick C.;
- Moed, Matthijs H.;
- Bonder, Marc Jan;
- van Galen, Michiel;
- Hailiang Mei;
- Zhernakova, Daria V.;
- van den Berg, Leonard H.;
- Deelen, Joris;
- van Dongen, Jenny;
- van Heemst, Diana;
- Hofman, Albert;
- Hottenga, Jouke J.;
- van der Kallen, Carla J. H.;
- Schalkwijk, Casper G.;
- Stehouwer, Coen D. A.;
- Tigchelaar, Ettje F.;
- Uitterlinden, André G.;
- Willemsen, Gonneke
Publication type:
Article
Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect.
Published in:
European Journal of Human Genetics, 2013, v. 21, n. 10, p. 1163, doi. 10.1038/ejhg.2012.303
By:
- Broer, Linda;
- Codd, Veryan;
- Nyholt, Dale R;
- Deelen, Joris;
- Mangino, Massimo;
- Willemsen, Gonneke;
- Albrecht, Eva;
- Amin, Najaf;
- Beekman, Marian;
- de Geus, Eco J C;
- Henders, Anjali;
- Nelson, Christopher P;
- Steves, Claire J;
- Wright, Margie J;
- de Craen, Anton J M;
- Isaacs, Aaron;
- Matthews, Mary;
- Moayyeri, Alireza;
- Montgomery, Grant W;
- Oostra, Ben A
Publication type:
Article
How to deal with the early GWAS data when imputing and combining different arrays is necessary.
Published in:
European Journal of Human Genetics, 2012, v. 20, n. 5, p. 572, doi. 10.1038/ejhg.2011.231
By:
- Uh, Hae-Won;
- Deelen, Joris;
- Beekman, Marian;
- Helmer, Quinta;
- Rivadeneira, Fernando;
- Hottenga, Jouke-Jan;
- Boomsma, Dorret I;
- Hofman, Albert;
- Uitterlinden, André G;
- Slagboom, P E;
- Böhringer, Stefan;
- Houwing-Duistermaat, Jeanine J
Publication type:
Article
Similar burden of pathogenic coding variants in exceptionally long‐lived individuals and individuals without exceptional longevity.
Published in:
Aging Cell, 2020, v. 19, n. 10, p. 1, doi. 10.1111/acel.13216
By:
- Gutman, Danielle;
- Lidzbarsky, Gabriel;
- Milman, Sofiya;
- Gao, Tina;
- Sin-Chan, Patrick;
- Gonzaga‐Jauregui, Claudia;
- Deelen, Joris;
- Shuldiner, Alan R.;
- Barzilai, Nir;
- Atzmon, Gil
Publication type:
Article
Copy number variation associates with mortality in long-lived individuals: a genome-wide assessment.
Published in:
Aging Cell, 2016, v. 15, n. 1, p. 49, doi. 10.1111/acel.12407
By:
- Nygaard, Marianne;
- Debrabant, Birgit;
- Tan, Qihua;
- Deelen, Joris;
- Andersen‐Ranberg, Karen;
- Craen, Anton J.M.;
- Beekman, Marian;
- Jeune, Bernard;
- Slagboom, Pieternella E.;
- Christensen, Kaare;
- Christiansen, Lene
Publication type:
Article
Gene expression analysis of mTOR pathway: association with human longevity.
Published in:
Aging Cell, 2013, v. 12, n. 1, p. 24, doi. 10.1111/acel.12015
By:
- Passtoors, Willemijn M.;
- Beekman, Marian;
- Deelen, Joris;
- van der Breggen, Ruud;
- Maier, Andrea B.;
- Guigas, Bruno;
- Derhovanessian, Evelyna;
- van Heemst, Diana;
- de Craen, Anton J. M.;
- Gunn, David A.;
- Pawelec, Graham;
- Slagboom, Pieternella E.
Publication type:
Article
Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.
Published in:
Aging Cell, 2011, v. 10, n. 4, p. 686, doi. 10.1111/j.1474-9726.2011.00705.x
By:
- Deelen, Joris;
- Beekman, Marian;
- Uh, Hae-Won;
- Helmer, Quinta;
- Kuningas, Maris;
- Christiansen, Lene;
- Kremer, Dennis;
- van der Breggen, Ruud;
- Suchiman, H. Eka D.;
- Lakenberg, Nico;
- van den Akker, Erik B.;
- Passtoors, Willemijn M.;
- Tiemeier, Henning;
- van Heemst, Diana;
- de Craen, Anton J.;
- Rivadeneira, Fernando;
- de Geus, Eco J;
- Perola, Markus;
- van der Ouderaa, Frans J.;
- Gunn, David A.
Publication type:
Article
Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47282-6
By:
- van der Spek, Ashley;
- Broer, Linda;
- Draisma, Harmen H. M.;
- Pool, René;
- Albrecht, Eva;
- Beekman, Marian;
- Mangino, Massimo;
- Raag, Mait;
- Nyholt, Dale R.;
- Dharuri, Harish K.;
- Codd, Veryan;
- Amin, Najaf;
- de Geus, Eco J. C.;
- Deelen, Joris;
- Demirkan, Ayse;
- Yet, Idil;
- Fischer, Krista;
- Haller, Toomas;
- Henders, Anjali K.;
- Isaacs, Aaron
Publication type:
Article
Aging as Accelerated Accumulation of Somatic Variants: Whole-Genome Sequencing of Centenarian and Middle-Aged Monozygotic Twin Pairs.
Published in:
Twin Research & Human Genetics, 2013, v. 16, n. 6, p. 1026, doi. 10.1017/thg.2013.73
By:
- Ye, Kai;
- Beekman, Marian;
- Lameijer, Eric-Wubbo;
- Zhang, Yanju;
- Moed, Matthijs H.;
- van den Akker, Erik B.;
- Deelen, Joris;
- Houwing-Duistermaat, Jeanine J.;
- Kremer, Dennis;
- Anvar, Seyed Yahya;
- Laros, Jeroen F. J.;
- Jones, David;
- Raine, Keiran;
- Blackburne, Ben;
- Potluri, Shobha;
- Long, Quan;
- Guryev, Victor;
- van der Breggen, Ruud;
- Westendorp, Rudi G. J.;
- ‘t Hoen, Peter A. C.
Publication type:
Article
Correlation of the two most frequent HLA haplotypes in the Italian population to the differential regional incidence of Covid-19.
Published in:
2020
By:
- Pisanti, Simona;
- Deelen, Joris;
- Gallina, Anna Maria;
- Caputo, Mariella;
- Citro, Marianna;
- Abate, Mario;
- Sacchi, Nicoletta;
- Vecchione, Carmine;
- Martinelli, Rosanna
Publication type:
journal article
A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function.
Published in:
PLoS Genetics, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.pgen.1003266
By:
- Porcu, Eleonora;
- Medici, Marco;
- Pistis, Giorgio;
- Volpato, Claudia B.;
- Wilson, Scott G.;
- Cappola, Anne R.;
- Bos, Steffan D.;
- Deelen, Joris;
- den Heijer, Martin;
- Freathy, Rachel M.;
- Lahti, Jari;
- Chunyu Liu;
- Lopez, Lorna M.;
- Nolte, Ilja M.;
- O'Connell, Jeffrey R.;
- Tanaka, Toshiko;
- Trompet, Stella;
- Arnold, Alice;
- Bandinelli, Stefania;
- Beekman, Marian
Publication type:
Article
Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes.
Published in:
2021
By:
- Deelen, Joris;
- Evans, Daniel S.;
- Arking, Dan E.;
- Tesi, Niccolò;
- Nygaard, Marianne;
- Liu, Xiaomin;
- Wojczynski, Mary K.;
- Biggs, Mary L.;
- van der Spek, Ashley;
- Atzmon, Gil;
- Ware, Erin B.;
- Sarnowski, Chloé;
- Smith, Albert V.;
- Seppälä, Ilkka;
- Cordell, Heather J.;
- Dose, Janina;
- Amin, Najaf;
- Arnold, Alice M.;
- Ayers, Kristin L.;
- Barzilai, Nir
Publication type:
Correction Notice
Estimation of metabolite networks with regard to a specific covariable: applications to plant and human data.
Published in:
Metabolomics, 2017, v. 13, n. 11, p. 1, doi. 10.1007/s11306-017-1263-2
By:
- Bartzis, Georgios;
- Deelen, Joris;
- Maia, Julio;
- Ligterink, Wilco;
- Hilhorst, Henk;
- Houwing-Duistermaat, Jeanine-J.;
- Eeuwijk, Fred;
- Uh, Hae-Won
Publication type:
Article
A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants.
Published in:
2017
By:
- Wood, Andrew R.;
- Jonsson, Anna;
- Jackson, Anne U.;
- Nan Wang;
- van Leewen, Nienke;
- Palmer, Nicholette D.;
- Sayuko Kobes;
- Deelen, Joris;
- Boquete-Vilarino, Lorena;
- Paananen, Jussi;
- Stanáčková, Alena;
- Boomsma, Dorret I.;
- de Geus, Eco J. C.;
- Eekhoff, Elisabeth M. W.;
- Fritsche, Andreas;
- Kramer, Mark;
- Nijpels, Giel;
- Simonis-Bik, Annemarie;
- van Haeften, Timon W.;
- Mahajan, Anubha
Publication type:
journal article
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 16, p. 4420, doi. 10.1093/hmg/ddu139
By:
- Deelen, Joris;
- Beekman, Marian;
- Uh, Hae-Won;
- Broer, Linda;
- Ayers, Kristin L.;
- Tan, Qihua;
- Kamatani, Yoichiro;
- Bennet, Anna M.;
- Tamm, Riin;
- Trompet, Stella;
- Guðbjartsson, Daníel F.;
- Flachsbart, Friederike;
- Rose, Giuseppina;
- Viktorin, Alexander;
- Fischer, Krista;
- Nygaard, Marianne;
- Cordell, Heather J.;
- Crocco, Paolina;
- van den Akker, Erik B.;
- Böhringer, Stefan
Publication type:
Article
A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention.
Published in:
Human Molecular Genetics, 2011, v. 20, n. 23, p. 4748, doi. 10.1093/hmg/ddr389
By:
- Sampietro, M. Lourdes;
- Trompet, Stella;
- Verschuren, Jeffrey J.W.;
- Talens, Rudolf P.;
- Deelen, Joris;
- Heijmans, Bastiaan T.;
- de Winter, Robbert J.;
- Tio, Rene A.;
- Doevendans, Pieter A.F.M.;
- Ganesh, Santhi K.;
- Nabel, Elizabeth G.;
- Westra, Harm-Jan;
- Franke, Lude;
- van den Akker, Erik B.;
- Westendorp, Rudi G.J.;
- Zwinderman, Aeilko H.;
- Kastrati, Adnan;
- Koch, Werner;
- Slagboom, P.Eline;
- de Knijff, Peter
Publication type:
Article
Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels.
Published in:
Nature Communications, 2015, v. 6, n. 3, p. 1, doi. 10.1038/ncomms7065
By:
- van Leeuwen, Elisabeth M.;
- Karssen, Lennart C.;
- Deelen, Joris;
- Isaacs, Aaron;
- Medina-Gomez, Carolina;
- Mbarek, Hamdi;
- Kanterakis, Alexandros;
- Trompet, Stella;
- Postmus, Iris;
- Verweij, Niek;
- van Enckevort, David J.;
- Huffman, Jennifer E.;
- White, Charles C.;
- Feitosa, Mary F.;
- Bartz, Traci M.;
- Manichaikul, Ani;
- Joshi, Peter K.;
- Peloso, Gina M.;
- Deelen, Patrick;
- van Dijk, Freerk
Publication type:
Article
Non-Homologous End-Joining Pathway Associated with Occurrence of Myocardial Infarction: Gene Set Analysis of Genome-Wide Association Study Data.
Published in:
PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056262
By:
- Verschuren, Jeffrey J. W.;
- Trompet, Stella;
- Deelen, Joris;
- Stott, David J.;
- Sattar, Naveed;
- Buckley, Brendan M.;
- Ford, Ian;
- Heijmans, Bastiaan T.;
- Guchelaar, Henk-Jan;
- Houwing-Duistermaat, Jeanine J.;
- Slagboom, P. Eline;
- Jukema, J. Wouter
Publication type:
Article
Transcriptional Profiling of Human Familial Longevity Indicates a Role for ASF1A and IL7R.
Published in:
PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0027759
By:
- Passtoors, Willemijn M.;
- Boer, Judith M.;
- Goeman, Jelle J.;
- van den Akker, Erik B.;
- Deelen, Joris;
- Zwaan, Bas J.;
- Scarborough, Ann;
- van der Breggen, Ruud;
- Vossen, Rolf H. A. M.;
- Houwing-Duistermaat, Jeanine J.;
- van Ommen, Gert Jan B.;
- Westendorp, Rudi G. J.;
- van Heemst, Diana;
- de Craen, Anton J. M.;
- White, Andrew J.;
- Gunn, David A.;
- Beekman, Marian;
- Slagboom, P. Eline
Publication type:
Article
The impact of low-frequency and rare variants on lipid levels.
Published in:
Nature Genetics, 2015, v. 47, n. 6, p. 589, doi. 10.1038/ng.3300
By:
- Surakka, Ida;
- Sarin, Antti-Pekka;
- Kettunen, Johannes;
- Hottenga, Jouke-Jan;
- de Geus, Eco J;
- Willemsen, Gonneke;
- Boomsma, Dorret I;
- Isaacs, Aaron;
- van Duijn, Cornelia M;
- Ladenvall, Claes;
- Beekman, Marian;
- Deelen, Joris;
- Slagboom, P Eline;
- Esko, Tõnu;
- Ried, Janina S;
- Nelson, Christopher P;
- Samani, Nilesh J;
- Willenborg, Christina;
- Erdmann, Jeanette;
- Blades, Matthew
Publication type:
Article
The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway.
Published in:
Diabetes, 2013, v. 62, n. 9, p. 3275, doi. 10.2337/db13-0227
By:
- Hart, Leen M. 't;
- Fritsche, Andreas;
- Nijpels, Giel;
- van Leeuwen, Nienke;
- Donnelly, Louise A.;
- Dekker, Jacqueline M.;
- Alssema, Marjan;
- Fadista, Joao;
- Carlotti, Françoise;
- Gjesing, Anette P.;
- Palmer, Colin N. A.;
- van Haeften, Timon W.;
- Herzberg-Schäfer, Silke A.;
- Simonis-Bik, Annemarie M. C.;
- Houwing-Duistermaat, Jeanine J.;
- Helmer, Quinta;
- Deelen, Joris;
- Guigas, Bruno;
- Hansen, Torben;
- Machicao, Fausto
Publication type:
Article
IL7R gene expression network associates with human healthy ageing.
Published in:
Immunity & Ageing, 2015, p. 1, doi. 10.1186/s12979-015-0048-6
By:
- Passtoors, Willemijn M.;
- van den Akker, Erik B.;
- Deelen, Joris;
- Maier, Andrea B.;
- van der Breggen, Ruud;
- Jansen, Rick;
- Trompet, Stella;
- van Heemst, Diana;
- Derhovanessian, Evelyna;
- Pawelec, Graham;
- van Ommen, Gert-Jan B.;
- Slagboom, P. Eline;
- Beekman, Marian
Publication type:
Article
Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process.
Published in:
2017
By:
- Bacalini, Maria Giulia;
- Deelen, Joris;
- Pirazzini, Chiara;
- De Cecco, Marco;
- Giuliani, Cristina;
- Lanzarini, Catia;
- Ravaioli, Francesco;
- Marasco, Elena;
- van Heemst, Diana;
- Suchiman, H. Eka D.;
- Slieker, Roderick;
- Giampieri, Enrico;
- Recchioni, Rina;
- Marcheselli, Fiorella;
- Salvioli, Stefano;
- Vitale, Giovanni;
- Olivieri, Fabiola;
- Spijkerman, Annemieke M. W.;
- Dollé, Martijn E. T.;
- Sedivy, John M.
Publication type:
journal article
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
Published in:
2015
By:
- Broer, Linda;
- Buchman, Aron S;
- Deelen, Joris;
- Evans, Daniel S;
- Faul, Jessica D;
- Lunetta, Kathryn L;
- Sebastiani, Paola;
- Smith, Jennifer A;
- Smith, Albert V;
- Tanaka, Toshiko;
- Yu, Lei;
- Arnold, Alice M;
- Aspelund, Thor;
- Benjamin, Emelia J;
- De Jager, Philip L;
- Eirkisdottir, Gudny;
- Evans, Denis A;
- Garcia, Melissa E;
- Hofman, Albert;
- Kaplan, Robert C
Publication type:
journal article
Survival analysis with delayed entry in selected families with application to human longevity.
Published in:
2018
By:
- Rodríguez-Girondo, Mar;
- Deelen, Joris;
- Slagboom, Eline P.;
- Houwing-Duistermaat, Jeanine J.
Publication type:
journal article
Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study.
Published in:
Diabetologia, 2018, v. 61, n. 1, p. 117, doi. 10.1007/s00125-017-4436-7
By:
- Molnos, Sophie;
- Wahl, Simone;
- Haid, Mark;
- Eekhoff, E. Marelise W.;
- Pool, René;
- Floegel, Anna;
- Deelen, Joris;
- Much, Daniela;
- Prehn, Cornelia;
- Breier, Michaela;
- Draisma, Harmen H.;
- van Leeuwen, Nienke;
- Simonis-Bik, Annemarie M. C.;
- Jonsson, Anna;
- Willemsen, Gonneke;
- Bernigau, Wolfgang;
- Wang-Sattler, Rui;
- Suhre, Karsten;
- Peters, Annette;
- Thorand, Barbara
Publication type:
Article
LDL cholesterol still a problem in old age? A Mendelian randomization study.
Published in:
International Journal of Epidemiology, 2015, v. 44, n. 2, p. 604, doi. 10.1093/ije/dyv031
By:
- Postmus, Iris;
- Deelen, Joris;
- Sedaghat, Sanaz;
- Trompet, Stella;
- de Craen, Anton J. M.;
- Heijmans, Bastiaan T.;
- Franco, Oscar H.;
- Hofman, Albert;
- Dehghan, Abbas;
- Slagboom, P. Eline;
- Westendorp, Rudi G. J.;
- Jukema, J. Wouter
Publication type:
Article
Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers.
Published in:
International Journal of Epidemiology, 2014, v. 43, n. 3, p. 878, doi. 10.1093/ije/dyt267
By:
- Deelen, Joris;
- Beekman, Marian;
- Codd, Veryan;
- Trompet, Stella;
- Broer, Linda;
- Hägg, Sara;
- Fischer, Krista;
- Thijssen, Peter E;
- Suchiman, H Eka D;
- Postmus, Iris;
- Uitterlinden, André G;
- Hofman, Albert;
- de Craen, Anton J M;
- Metspalu, Andres;
- Pedersen, Nancy L;
- van Duijn, Cornelia M;
- Wouter Jukema, J;
- Houwing-Duistermaat, Jeanine J;
- Samani, Nilesh J;
- Eline Slagboom, P
Publication type:
Article
Identifying the genomic determinants of aging and longevity in human population studies: Progress and challenges.
Published in:
BioEssays, 2013, v. 35, n. 4, p. 386, doi. 10.1002/bies.201200148
By:
- Deelen, Joris;
- Beekman, Marian;
- Capri, Miriam;
- Franceschi, Claudio;
- Slagboom, P. Eline
Publication type:
Article
From mutation to mechanism: deciphering the molecular function of genetic variants linked to human ageing.
Published in:
Briefings in Functional Genomics, 2022, v. 21, n. 1, p. 13, doi. 10.1093/bfgp/elab005
By:
- Baghdadi, Maarouf;
- Hinterding, Helena M;
- Partridge, Linda;
- Deelen, Joris
Publication type:
Article
Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study.
Published in:
PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0189886
By:
- Gudmundsdottir, Valborg;
- Pedersen, Helle Krogh;
- Allebrandt, Karla Viviani;
- Brorsson, Caroline;
- van Leeuwen, Nienke;
- Banasik, Karina;
- Mahajan, Anubha;
- Groves, Christopher J.;
- van de Bunt, Martijn;
- Dawed, Adem Y.;
- Fritsche, Andreas;
- Staiger, Harald;
- Simonis-Bik, Annemarie M. C.;
- Deelen, Joris;
- Kramer, Mark H. H.;
- Dietrich, Axel;
- Hübschle, Thomas;
- Willemsen, Gonneke;
- Häring, Hans-Ulrich;
- de Geus, Eco J. C.
Publication type:
Article
A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots.
Published in:
Journal of Investigative Dermatology, 2015, v. 135, n. 7, p. 1735, doi. 10.1038/jid.2015.62
By:
- Jacobs, Leonie C;
- Hamer, Merel A;
- Gunn, David A;
- Deelen, Joris;
- Lall, Jaspal S;
- van Heemst, Diana;
- Uh, Hae-Won;
- Hofman, Albert;
- Uitterlinden, André G;
- Griffiths, Christopher E M;
- Beekman, Marian;
- Slagboom, P Eline;
- Kayser, Manfred;
- Liu, Fan;
- Nijsten, Tamar
Publication type:
Article
Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants.
Published in:
European Journal of Epidemiology, 2014, v. 29, n. 9, p. 629, doi. 10.1007/s10654-014-9940-1
By:
- Broer, Linda;
- Raschenberger, Julia;
- Deelen, Joris;
- Mangino, Massimo;
- Codd, Veryan;
- Pietiläinen, Kirsi;
- Albrecht, Eva;
- Amin, Najaf;
- Beekman, Marian;
- Craen, Anton;
- Gieger, Christian;
- Haun, Margot;
- Henneman, Peter;
- Herder, Christian;
- Hovatta, Iiris;
- Laser, Annika;
- Kedenko, Lyudmyla;
- Koenig, Wolfgang;
- Kollerits, Barbara;
- Moilanen, Eeva
Publication type:
Article
The effect of standardized food intake on the association between BMI and <sup>1</sup>H-NMR metabolites.
Published in:
Scientific Reports, 2016, p. 38980, doi. 10.1038/srep38980
By:
- Schutte, Bianca A. M.;
- van den Akker, Erik B.;
- Deelen, Joris;
- van de Rest, Ondine;
- van Heemst, Diana;
- Feskens, Edith J. M.;
- Beekman, Marian;
- Slagboom, P. Eline
Publication type:
Article
Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice.
Published in:
Scientific Reports, 2016, p. 30484, doi. 10.1038/srep30484
By:
- Rusli, Fenni;
- Deelen, Joris;
- Andriyani, Evi;
- Boekschoten, Mark V.;
- Lute, Carolien;
- van den Akker, Erik B.;
- Müller, Michael;
- Beekman, Marian;
- Steegenga, Wilma T
Publication type:
Article
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11311-9
By:
- Deelen, Joris;
- Kettunen, Johannes;
- Fischer, Krista;
- van der Spek, Ashley;
- Trompet, Stella;
- Kastenmüller, Gabi;
- Boyd, Andy;
- Zierer, Jonas;
- van den Akker, Erik B.;
- Ala-Korpela, Mika;
- Amin, Najaf;
- Demirkan, Ayse;
- Ghanbari, Mohsen;
- van Heemst, Diana;
- Ikram, M. Arfan;
- van Klinken, Jan Bert;
- Mooijaart, Simon P.;
- Peters, Annette;
- Salomaa, Veikko;
- Sattar, Naveed
Publication type:
Article
A meta-analysis of genome-wide association studies identifies multiple longevity genes.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11558-2
By:
- Deelen, Joris;
- Evans, Daniel S.;
- Arking, Dan E.;
- Tesi, Niccolò;
- Nygaard, Marianne;
- Liu, Xiaomin;
- Wojczynski, Mary K.;
- Biggs, Mary L.;
- van der Spek, Ashley;
- Atzmon, Gil;
- Ware, Erin B.;
- Sarnowski, Chloé;
- Smith, Albert V.;
- Seppälä, Ilkka;
- Cordell, Heather J.;
- Dose, Janina;
- Amin, Najaf;
- Arnold, Alice M.;
- Ayers, Kristin L.;
- Barzilai, Nir
Publication type:
Article
Association between the rs7903146 Polymorphism in the TCF7L2 Gene and Parameters Derived with Continuous Glucose Monitoring in Individuals without Diabetes.
Published in:
PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0149992
By:
- van der Kroef, Sabrina;
- Noordam, Raymond;
- Deelen, Joris;
- Akintola, Abimbola A.;
- Jansen, Steffy W. M.;
- Postmus, Iris;
- Wijsman, Carolien A.;
- Beekman, Marian;
- Mooijaart, Simon P.;
- Slagboom, P. Eline;
- van Heemst, Diana
Publication type:
Article

Found: 46