Works matching AU Morgan, Todd E.

Results: 44

Nanoparticulate matter exposure results in neuroinflammatory changes in the corpus callosum.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0206934

By:

Babadjouni, Robin;
Patel, Arati;
Liu, Qinghai;
Shkirkova, Kristina;
Lamorie-Foote, Krista;
Connor, Michelle;
Hodis, Drew M.;
Cheng, Hank;
Sioutas, Constantinos;
Morgan, Todd E.;
Finch, Caleb E.;
Mack, William J.

Publication type:

Article

Particulate matter exposure and chronic cerebral hypoperfusion promote oxidative stress and induce neuronal and oligodendrocyte apoptosis in male mice.

Published in:

Journal of Neuroscience Research, 2023, v. 101, n. 3, p. 384, doi. 10.1002/jnr.25153

By:

Lamorie‐Foote, Krista;
Liu, Qinghai;
Shkirkova, Kristina;
Ge, Brandon;
He, Shannon;
Morgan, Todd E.;
Mack, Wendy J.;
Sioutas, Constantinos;
Finch, Caleb E.;
Mack, William J.

Publication type:

Article

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase.

Published in:

Nature Medicine, 2008, v. 14, n. 7, p. 723, doi. 10.1038/nm1784

By:

Faghihi, Mohammad Ali;
Modarresi, Farzaneh;
Khalil, Ahmad M.;
Wood, Douglas E.;
Sahagan, Barbara G.;
Morgan, Todd E.;
Finch, Caleb E.;
St. Laurent III, Georges;
Kenny, Paul J.;
Wahlestedt, Claes

Publication type:

Article

Prenatal Exposure to Urban Air Nanoparticles in Mice Causes Altered Neuronal Differentiation and Depression-Like Responses

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064128

By:

Davis, David A.;
Bortolato, Marco;
Godar, Sean C.;
Sander, Thomas K.;
Iwata, Nahoko;
Pakbin, Payam;
Shih, Jean C.;
Berhane, Kiros;
McConnell, Rob;
Sioutas, Constantinos;
Finch, Caleb E.;
Morgan, Todd E.

Publication type:

Article

Continuous versus Cyclic Progesterone Exposure Differentially Regulates Hippocampal Gene Expression and Functional Profiles.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031267

By:

Liqin Zhao;
Morgan, Todd E.;
Zisu Mao;
Lin, Sharon;
Cadenas, Enrique;
Finch, Caleb E.;
Pike, Christian J.;
Mack, Wendy J.;
Brinton, Roberta D.

Publication type:

Article

Joint Genome-Wide Profiling of miRNA and mRNA Expression in Alzheimer's Disease Cortex Reveals Altered miRNA Regulation.

Published in:

PLoS ONE, 2010, v. 5, n. 2, p. 1, doi. 10.1371/journal.pone.0008898

By:

Nunez-Iglesias, Juan;
Chun-Chi Liu;
Morgan, Todd E.;
Finch, Caleb E.;
Xianghong Jasmine Zhou

Publication type:

Article

Absence of Glial Fibrillary Acidic Protein and Vimentin Prevents Hypertrophy of Astrocytic Processes and Improves Post-Traumatic Regeneration.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 21, p. 5016, doi. 10.1523/JNEUROSCI.0820-04.2004

By:

Wilhelmsson, Ulrika;
Li, Lizhen;
Pekna, Marcela;
Berthold, Claes-Henric;
Blom, Sofia;
Eliasson, Camilla;
Renner, Oliver;
Bushong, Eric;
Ellisman, Mark;
Morgan, Todd E.;
Pekny, Milos

Publication type:

Article

Iron‐associated lipid peroxidation in Alzheimer's disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2025, v. 21, n. 1, p. 1, doi. 10.1002/alz.14541

By:

Thorwald, Max A.;
Godoy‐Lugo, Jose A.;
Garcia, Gilberto;
Silva, Justine;
Kim, Minhoo;
Christensen, Amy;
Mack, Wendy J.;
Head, Elizabeth;
O'Day, Peggy A.;
Benayoun, Bérénice A.;
Morgan, Todd E.;
Pike, Christian J.;
Higuchi‐Sanabria, Ryo;
Forman, Henry Jay;
Finch, Caleb E.

Publication type:

Article

Reductions in ApoE and GPx4 highlight the Alzheimer's disease lipid raft vulnerability.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054511

By:

Thorwald, Max A;
Cacciottolo, Mafalda;
Forman, Henry Jay;
Morgan, Todd E;
Finch, Caleb E

Publication type:

Article

Inhibiting Bach1 enhanced the activation of Nrf2 signaling and the degradation of HNE in response to oxidative stress.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.053235

By:

Zhang, Hongqiao;
Thorwald, Max A;
D'agostino, Carla;
Morgan, Todd E;
Finch, Caleb E;
Forman, Henry J

Publication type:

Article

The APOE gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 2, p. 175, doi. 10.1002/alz.12230

By:

Haghani, Amin;
Thorwald, Max;
Morgan, Todd E.;
Finch, Caleb E.

Publication type:

Article

Reduction of lipid peroxidase levels in EFAD mouse model: Molecular and cell biology/oxidative stress.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044143

By:

Cacciottolo, Mafalda;
Thorwald, Max A.;
Forman, Henry J.;
Morgan, Todd E.;
Finch, Caleb E.

Publication type:

Article

Early developmental exposure to air pollution increases the risk of Alzheimers disease and amyloid production: Studies in mouse and Caenorhabditis elegans: Molecular and cell biology/APP/Abeta/amyloid.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043846

By:

Haghani, Amin;
Johnson, Riachard G.;
Dalton, Hans;
Feinberg, Jason I.;
Lewis, Kristy C.;
Ladd‐Acosta, Christine;
Woodward, Nicholas C.;
Safi, Nikoo;
Jaffe, Andrew E.;
Allayee, Hooman;
Sioutas, Constantinos;
Campbell, Daniel B.;
Volk, Heather E.;
Curran, Sean P;
Finch, Caleb E.;
Morgan, Todd E.

Publication type:

Article

P4‐092: ENVIRONMENTAL INFLUENCES ON GENE NETWORKS OF COGNITIVE AGING: HOW SEX AND APOE INTERACT WITH AMBIENT AIR POLLUTION (AAP) AND CIGARETTE SMOKE (CS).

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1310, doi. 10.1016/j.jalz.2019.06.3752

By:

Haghani, Amin;
Cacciottolo, Mafalda;
Doty, Kevin R.;
Sioutas, Constantinos;
Town, Terrence;
Morgan, Todd E.;
Morgan, Levine;
Finch, Caleb E.

Publication type:

Article

P2‐203: AIR POLLUTION NANOPARTICULATE MATTER CAUSES WHITE MATTER DAMAGE AND MICROGLIAL ACTIVATION IN A MOUSE MODEL.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P654, doi. 10.1016/j.jalz.2019.06.2610

By:

Connor, Michelle;
Shkirkova, Kristina;
Lamorie-Foote, Krista;
Patel, Arati;
Lui, Qinghai;
Sioutas, Constantinos;
Finch, Caleb E.;
Morgan, Todd E.;
Mack, William J.

Publication type:

Article

P2‐169: DOES HYPERTENSION CONTRIBUTE TO CEREBRAL MICROBLEEDS IN ALZHEIMER TRANSGENIC MICE?

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P641, doi. 10.1016/j.jalz.2019.06.2576

By:

Cacciottolo, Mafalda;
Morgan, Todd E.;
Finch, Caleb E.

Publication type:

Article

P1‐212: MICROGLIAL INTERACTIONS WITH AMYLOID PLAQUES ARE MODULATED BY SEX AND APOE GENOTYPE IN EFAD MICE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P317, doi. 10.1016/j.jalz.2019.06.767

By:

Stephen, Terri;
Cacciottolo, Mafalda;
Balu, Deebika;
Morgan, Todd E.;
Ladu, Mary Jo;
Finch, Caleb E.;
Pike, Christian J.

Publication type:

Article

P1‐204: A NOVEL PHARMACOLOGICAL INTERVENTION TO NEUROINFLAMMATORY OUTCOMES OF AIR POLLUTION: THE GAMMA SECRETASE MODULATOR BPN‐15606 ATTENUATED MICROGLIAL AND AMYLOID INDUCTION BY URBAN NANO‐PARTICULATE (NPM) IN YOUNG MALE C57BL/6J MICE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P315, doi. 10.1016/j.jalz.2019.06.759

By:

D'agostino, Carla;
Cacciottolo, Mafalda;
Shirmohammadi, Farimah;
Sioutas, Constantinos;
Wagner, Steven L.;
Tanzi, Rudolph E.;
Morgan, Todd E.;
Finch, Caleb E.

Publication type:

Article

P1‐021: TRANSCRIPTOMIC PROFILING OF MICROGLIA FROM AN ALZHEIMER'S DISEASE MOUSE MODEL AND FROM HUMAN INDUCED PLURIPOTENT STEM CELLS REVEALS EFFECTS OF THE APOE4 GENOTYPE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P238, doi. 10.1016/j.jalz.2019.06.046

By:

Moser, V. Alexandra;
Sances, Samuel;
Morgan, Todd E.;
Finch, Caleb E.;
Ladu, Mary Jo;
Pike, Christian J.;
Svendsen, Clive N.

Publication type:

Article

P3‐148: OXIDATIVE STRESS FROM TRAFFIC‐RELATED AIR POLLUTANTS (TRAP) INDUCES PRO‐AMYLOIDOGENIC LIPID RAFT ALTERATION IN AD MODELS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1124, doi. 10.1016/j.jalz.2018.06.1505

By:

Cacciottolo, Mafalda;
Morgan, Todd E.;
Saffari, Arian;
Sioutas, Constantinos;
Forman, Henry J.;
Finch, Caleb E.

Publication type:

Article

TGF-β1 is an organizer of responses to neurodgeneration.

Published in:

Journal of Cellular Biochemistry, 1993, v. 53, n. 4, p. 314, doi. 10.1002/jcb.240530408

By:

Finch, Caleb E.;
Laping, Nicholas J.;
Morgan, Todd E.;
Nichols, Nancy R.;
Pasinetti, Giulio M.

Publication type:

Article

Air Pollution Alters Caenorhabditis elegans Development and Lifespan: Responses to Traffic-Related Nanoparticulate Matter.

Published in:

2019

By:

Haghani, Amin;
Dalton, Hans M;
Safi, Nikoo;
Shirmohammadi, Farimah;
Sioutas, Constantinos;
Morgan, Todd E;
Finch, Caleb E;
Curran, Sean P

Publication type:

journal article

Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice.

Published in:

Scientific Reports, 2017, p. 40919, doi. 10.1038/srep40919

By:

Lee, Amy S.;
Brandhorst, Sebastian;
Rangel, Daisy F.;
Navarrete, Gerardo;
Cohen, Pinchas;
Longo, Valter D.;
Chen, Jeannie;
Groshen, Susan;
Morgan, Todd E.;
Dubeau, Louis

Publication type:

Article

Astrocytic estrogen receptors and impaired neurotrophic responses in a rat model of perimenopause.

Published in:

Frontiers in Aging Neuroscience, 2015, v. 7, p. 1, doi. 10.3389/fnagi.2015.00179

By:

Morgan, Todd E.;
Finch, Caleb E.;
Griffith, William;
Wandosell, Francisco G.;
Valasani, Koteswara Rao

Publication type:

Article

Hepatic but Not CNS-Expressed Human C-Reactive Protein Inhibits Experimental Autoimmune Encephalomyelitis in Transgenic Mice.

Published in:

Autoimmune Diseases (2090-0422), 2015, v. 2015, p. 1, doi. 10.1155/2015/640171

By:

Wright, Tyler T.;
Jimenez, Rachel V.;
Morgan, Todd E.;
Bali, Namrata;
Hou, Xiaogang;
McCrory, Mark A.;
Finch, Caleb E.;
Szalai, Alexander J.

Publication type:

Article

Cerebral cortex and blood transcriptome changes in mouse neonates prenatally exposed to air pollution particulate matter.

Published in:

Journal of Neurodevelopmental Disorders, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s11689-021-09380-3

By:

Haghani, Amin;
Feinberg, Jason I.;
Lewis, Kristy C.;
Ladd-Acosta, Christine;
Johnson, Richard G.;
Jaffe, Andrew E.;
Sioutas, Constantinos;
Finch, Caleb E.;
Campbell, Daniel B.;
Morgan, Todd E.;
Volk, Heather E.

Publication type:

Article

Functional annotation and network reconstruction through cross-platform integration of microarray data.

Published in:

Nature Biotechnology, 2005, v. 23, n. 2, p. 238, doi. 10.1038/nbt1058

By:

Zhou, Xianghong Jasmine;
Kao, Ming-Chih J;
Huang, Haiyan;
Wong, Angela;
Nunez-Iglesias, Juan;
Primig, Michael;
Aparicio, Oscar M;
Finch, Caleb E;
Morgan, Todd E;
Wong, Wing Hung

Publication type:

Article

Air Pollution Particulate Matter Exposure and Chronic Cerebral Hypoperfusion and Measures of White Matter Injury in a Murine Model.

Published in:

Environmental Health Perspectives, 2021, v. 129, n. 8, p. 1, doi. 10.1289/EHP8792

By:

Qinghai Liu;
Shkirkova, Kristina;
Lamorie-Foote, Krista;
Connor, Michelle;
Patel, Arati;
Babadjouni, Robin;
Huuskonen, Mikko;
Montagne, Axel;
Baertsch, Hans;
Hongqiao Zhang;
Jiu-Chiuan Chen;
Mack, Wendy J.;
Walcott, Brian P.;
Zlokovic, Berislav V.;
Sioutas, Constantinos;
Morgan, Todd E.;
Finch, Caleb E.;
Mack, William J.

Publication type:

Article

Nanoscale Particulate Matter from Urban Traffic Rapidly Induces Oxidative Stress and Inflammation in Olfactory Epithelium with Concomitant Effects on Brain.

Published in:

Environmental Health Perspectives, 2016, v. 124, n. 10, p. 1537, doi. 10.1289/EHP134

By:

Cheng, Hank;
Saffari, Arian;
Sioutas, Constantinos;
Forman, Henry J.;
Morgan, Todd E.;
Finch, Caleb E.

Publication type:

Article

Glutamatergic Neurons in Rodent Models Respond to Nanoscale Particulate Urban Air Pollutants in Vivo and in Vitro.

Published in:

Environmental Health Perspectives, 2011, v. 119, n. 7, p. 1003, doi. 10.1289/ehp.1002973

By:

Morgan, Todd E.;
Davis, David A.;
Iwata, Nahoko;
Tanner, Jeremy A.;
Snyder, David;
Ning, Zhi;
Kam, Winnie;
Hsu, Yu-Tien;
Winkler, Jeremy W.;
Chen, Jiu-Chiuan;
Petasis, Nicos A.;
Baudry, Michel;
Sioutas, Constantinos;
Finch, Caleb E.

Publication type:

Article

Kainic Acid and Decorticating Lesions Stimulate the Synthesis of C1q Protein in Adult Rat Brain.

Published in:

Journal of Neurochemistry, 1997, v. 68, n. 5, p. 2046, doi. 10.1046/j.1471-4159.1997.68052046.x

By:

Goldsmith, Sara K.;
Wals, Pat;
Rozovsky, Irina;
Morgan, Todd E.;
Finch, Caleb E.

Publication type:

Article

GRP78/BiP is a novel downstream target of IGF-1 receptor mediated signaling.

Published in:

Journal of Cellular Physiology, 2012, v. 227, n. 12, p. 3803, doi. 10.1002/jcp.24090

By:

Pfaffenbach, Kyle T.;
Pong, Michelle;
Morgan, Todd E.;
Wang, Hongjun;
Ott, Kate;
Zhou, Beiyun;
Longo, Valter D.;
Lee, Amy S.

Publication type:

Article

Urban air pollutants reduce synaptic function of CA1 neurons via an NMDA/NȮ pathway in vitro.

Published in:

Journal of Neurochemistry, 2013, v. 127, n. 4, p. 509, doi. 10.1111/jnc.12395

By:

Davis, David A.;
Akopian, Garnik;
Walsh, John P.;
Sioutas, Constantinos;
Morgan, Todd E.;
Finch, Caleb E.

Publication type:

Article

Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease.

Published in:

Science Translational Medicine, 2017, v. 9, n. 377, p. 1, doi. 10.1126/scitranslmed.aai8700

By:

Min Wei;
Brandhorst, Sebastian;
Shelehchi, Mahshid;
Mirzaei, Hamed;
Chia Wei Cheng;
Budniak, Julia;
Groshen, Susan;
Mack, Wendy J.;
Guen, Esra;
Di Biase, Stefano;
Cohen, Pinchas;
Morgan, Todd E.;
Dorff, Tanya;
Kurt Hong;
Michalsen, Andreas;
Laviano, Alessandro;
Longo, Valter D.

Publication type:

Article

Stroke Damage Is Exacerbated by Nano-Size Particulate Matter in a Mouse Model.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0153376

By:

Liu, Qinghai;
Babadjouni, Robin;
Radwanski, Ryan;
Cheng, Hank;
Patel, Arati;
Hodis, Drew M.;
He, Shuhan;
Baumbacher, Peter;
Russin, Jonathan J.;
Morgan, Todd E.;
Sioutas, Constantinos;
Finch, Caleb E.;
Mack, William J.

Publication type:

Article

Urban traffic-derived nanoparticulate matter reduces neurite outgrowth via TNFα in vitro.

Published in:

2016

By:

Hank Cheng;
Davis, David A.;
Hasheminassab, Sina;
Sioutas, Constantinos;
Morgan, Todd E.;
Finch, Caleb E.;
Cheng, Hank

Publication type:

journal article

Exposure to Nanoscale Particulate Matter from Gestation to Adulthood Impairs Metabolic Homeostasis in Mice.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37704-2

By:

Woodward, Nicholas C.;
Crow, Amanda L.;
Zhang, Yang;
Epstein, Sam;
Hartiala, Jaana;
Johnson, Richard;
Kocalis, Heidi;
Saffari, Arian;
Sankaranarayanan, Ishwarya;
Akbari, Omid;
Ramanathan, Gajalakshmi;
Araujo, Jesus A.;
Finch, Caleb E.;
Bouret, Sebastien G.;
Sioutas, Constantinos;
Morgan, Todd E.;
Allayee, Hooman

Publication type:

Article

Adult mouse hippocampal transcriptome changes associated with long-term behavioral and metabolic effects of gestational air pollution toxicity.

Published in:

Translational Psychiatry, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41398-020-00907-1

By:

Haghani, Amin;
Johnson, Richard G.;
Woodward, Nicholas C.;
Feinberg, Jason I.;
Lewis, Kristy;
Ladd-Acosta, Christine;
Safi, Nikoo;
Jaffe, Andrew E.;
Sioutas, Constantinos;
Allayee, Hooman;
Campbell, Daniel B.;
Volk, Heather E.;
Finch, Caleb E.;
Morgan, Todd E.

Publication type:

Article

Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45260-9

By:

Brandhorst, Sebastian;
Levine, Morgan E.;
Wei, Min;
Shelehchi, Mahshid;
Morgan, Todd E.;
Nayak, Krishna S.;
Dorff, Tanya;
Hong, Kurt;
Crimmins, Eileen M.;
Cohen, Pinchas;
Longo, Valter D.

Publication type:

Article

Effects of ambient particulate matter on vascular tissue: a review.

Published in:

Journal of Toxicology & Environmental Health: Part B, 2020, v. 23, n. 7, p. 319, doi. 10.1080/10937404.2020.1822971

By:

Shkirkova, Kristina;
Lamorie-Foote, Krista;
Connor, Michelle;
Patel, Arati;
Barisano, Giuseppe;
Baertsch, Hans;
Liu, Qinghai;
Morgan, Todd E.;
Sioutas, Constantinos;
Mack, William J.

Publication type:

Article

Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo.

Published in:

2017

By:

Woodward, Nicholas C.;
Levine, Morgan C.;
Haghani, Amin;
Shirmohammadi, Farimah;
Saffari, Arian;
Sioutas, Constantinos;
Morgan, Todd E.;
Finch, Caleb E.

Publication type:

journal article

Cell resilience in species life spans: a link to inflammation?

Published in:

Aging Cell, 2010, v. 9, n. 4, p. 519, doi. 10.1111/j.1474-9726.2010.00578.x

By:

Finch, Caleb E.;
Morgan, Todd E.;
Longo, Valter D.;
de Magalhaes, Joao P.

Publication type:

Article

Air Pollution Particulate Matter Amplifies White Matter Vascular Pathology and Demyelination Caused by Hypoperfusion.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.785519

By:

Huuskonen, Mikko T.;
Liu, Qinghai;
Lamorie-Foote, Krista;
Shkirkova, Kristina;
Connor, Michelle;
Patel, Arati;
Montagne, Axel;
Baertsch, Hans;
Sioutas, Constantinos;
Morgan, Todd E.;
Finch, Caleb E.;
Zlokovic, Berislav V.;
Mack, William J.

Publication type:

Article

Nanoparticulate matter exposure results in white matter damage and an inflammatory microglial response in an experimental murine model.

Published in:

PLoS ONE, 2021, v. 16, n. 7, p. 1, doi. 10.1371/journal.pone.0253766

By:

Connor, Michelle;
Lamorie-Foote, Krista;
Liu, Qinghai;
Shkirkova, Kristina;
Baertsch, Hans;
Sioutas, Constantinos;
Morgan, Todd E.;
Finch, Caleb E.;
Mack, William J.

Publication type:

Article