Works matching AU Chu, Yaping

Results: 41

Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity.

Published in:

Neural Plasticity, 2019, p. 1, doi. 10.1155/2019/6286197

By:

Emerich, Dwaine F.;
Kordower, Jeffrey H.;
Chu, Yaping;
Thanos, Chris;
Bintz, Briannan;
Paolone, Giovanna;
Wahlberg, Lars U.

Publication type:

Article

Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease.

Published in:

Nature Medicine, 2008, v. 14, n. 5, p. 504, doi. 10.1038/nm1747

By:

Kordower, Jeffrey H.;
Yaping Chu;
Hauser, Robert A.;
Freeman, Thomas B.;
Olanow, C. Warren

Publication type:

Article

Dehydroepiandrosterone plus climen supplementation shows better effects than dehydroepiandrosterone alone on infertility patients with diminished ovarian reserve of low-FSH level undergoing in-vitro fertilization cycles: a randomized controlled trial.

Published in:

Reproductive Biology & Endocrinology, 2016, v. 14, p. 1, doi. 10.1186/s12958-016-0139-z

By:

Huanhuan Zhang;
Yaping Chu;
Ping Zhou;
Xiaojin He;
Qianhua Xu;
Zhiguo Zhang;
Yunxia Cao;
Zhaolian Wei

Publication type:

Article

Bioactivity of AAV2-neurturin gene therapy (CERE-120): Differences between Parkinson's disease and nonhuman primate brains.

Published in:

Movement Disorders, 2011, v. 26, n. 1, p. 27, doi. 10.1002/mds.23442

By:

Bartus, Raymond T.;
Herzog, Christopher D.;
Chu, Yaping;
Wilson, Alistair;
Brown, Lamar;
Siffert, Joao;
Johnson, Eugene M.;
Olanow, C. Warren;
Mufson, Elliott J.;
Kordower, Jeffrey H.

Publication type:

Article

Transplanted dopaminergic neurons develop PD pathologic changes: A second case report.

Published in:

Movement Disorders, 2008, v. 23, n. 16, p. 2303, doi. 10.1002/mds.22369

By:

Kordower, Jeffrey H.;
Chu, Yaping;
Hauser, Robert A.;
Olanow, C.Warren;
Freeman, Thomas B.

Publication type:

Article

Neuropathological study 16 years after autologous adrenal medullary transplantation in a Parkinson's disease patient.

Published in:

Movement Disorders, 2007, v. 22, n. 11, p. 1630, doi. 10.1002/mds.21528

By:

Kompoliti, Katie;
Chu, Yaping;
Shannon, Kathleen M.;
Kordower, Jeffrey H.

Publication type:

Article

PGC−1α Promoter Methylation in Parkinson’s Disease.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0134087

By:

Su, Xiaomin;
Chu, Yaping;
Kordower, Jeffrey H.;
Li, Bin;
Cao, Hong;
Huang, Liang;
Nishida, Maki;
Song, Lei;
Wang, Difei;
Federoff, Howard J.

Publication type:

Article

Proximity proteomics reveals unique and shared pathological features between multiple system atrophy and Parkinson's disease.

Published in:

Acta Neuropathologica Communications, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40478-025-01958-5

By:

Choi, Solji G.;
Tittle, Tyler R.;
Barot, Raj R.;
Betts, Dakota J.;
Gallagher, Johnie J.;
Kordower, Jeffrey H.;
Chu, Yaping;
Killinger, Bryan A.

Publication type:

Article

Analysis of YFP(J16)-R6/2 reportermice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 18, p. 5285, doi. 10.1093/hmg/ddv248

By:

Gatto, Rodolfo G.;
Yaping Chu;
Ye, Allen Q.;
Price, Steven D.;
Tavassoli, Ehsan;
Buenaventura, Andrea;
Brady, Scott T.;
Magin, Richard L.;
Kordower, Jeffrey H.;
Morfini, Gerardo A.

Publication type:

Article

The Prion Hypothesis of Parkinson's Disease.

Published in:

Current Neurology & Neuroscience Reports, 2015, v. 15, n. 5, p. 1, doi. 10.1007/s11910-015-0549-x

By:

Chu, Yaping;
Kordower, Jeffrey

Publication type:

Article

Nigrostriatal tau pathology in parkinsonism and Parkinson's disease.

Published in:

Brain: A Journal of Neurology, 2024, v. 147, n. 2, p. 444, doi. 10.1093/brain/awad388

By:

Chu, Yaping;
Hirst, Warren D;
Federoff, Howard J;
Harms, Ashley S;
Stoessl, A Jon;
Kordower, Jeffrey H

Publication type:

Article

Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease.

Published in:

2020

By:

Chu, Yaping;
Bartus, Raymond T;
Manfredsson, Fredric P;
Olanow, C Warren;
Kordower, Jeffrey H

Publication type:

journal article

Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes.

Published in:

2019

By:

Chu, Yaping;
Muller, Scott;
Tavares, Adriana;
Barret, Olivier;
Alagille, David;
Seibyl, John;
Tamagnan, Gilles;
Marek, Ken;
Luk, Kelvin C;
Trojanowski, John Q;
Lee, Virginia M Y;
Kordower, Jeffrey H

Publication type:

journal article

Temporal evolution of microglia and α-synuclein accumulation following foetal grafting in Parkinson's disease.

Published in:

2019

By:

Olanow, C Warren;
Savolainen, Mari;
Chu, Yaping;
Halliday, Glenda M;
Kordower, Jeffrey H

Publication type:

journal article

Disease duration and the integrity of the nigrostriatal system in Parkinson's disease.

Published in:

2013

By:

Kordower, Jeffrey H;
Olanow, C Warren;
Dodiya, Hemraj B;
Chu, Yaping;
Beach, Thomas G;
Adler, Charles H;
Halliday, Glenda M;
Bartus, Raymond T

Publication type:

journal article

Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease.

Published in:

Brain: A Journal of Neurology, 2013, v. 136, n. 8, p. 2419, doi. 10.1093/brain/awt192

By:

Kordower, Jeffrey H.;
Olanow, C. Warren;
Dodiya, Hemraj B.;
Chu, Yaping;
Beach, Thomas G.;
Adler, Charles H.;
Halliday, Glenda M.;
Bartus, Raymond T.

Publication type:

Article

Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease.

Published in:

2012

By:

Chu Y;
Morfini GA;
Langhamer LB;
He Y;
Brady ST;
Kordower JH;
Chu, Yaping;
Morfini, Gerardo A;
Langhamer, Lori B;
He, Yinzhen;
Brady, Scott T;
Kordower, Jeffrey H

Publication type:

journal article

Alterations in axonal transport motor proteins in sporadic and experimental Parkinson’s disease.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 7, p. 2058, doi. 10.1093/brain/aws133

By:

Chu, Yaping;
Morfini, Gerardo A.;
Langhamer, Lori B.;
He, Yinzhen;
Brady, Scott T.;
Kordower, Jeffrey H.

Publication type:

Article

Do subjects with minimal motor features have prodromal Parkinson disease?

Published in:

2018

By:

Chu, Yaping;
Buchman, Aron S.;
Olanow, C. Warren;
Kordower, Jeffrey H.

Publication type:

journal article

Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a Parkinson disease patient.

Published in:

2017

By:

Kordower, Jeffrey H.;
Goetz, Christopher G.;
Chu, Yaping;
Halliday, Glenda M.;
Nicholson, Daniel A.;
Musial, Timothy F.;
Marmion, David J.;
Stoessl, A. Jon;
Sossi, Vesna;
Freeman, Thomas B.;
Olanow, C. Warren

Publication type:

journal article

Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5198, doi. 10.1002/alz.13868

By:

Beckman, Danielle;
Diniz, Giovanne B.;
Ott, Sean;
Hobson, Brad;
Chaudhari, Abhijit J.;
Muller, Scott;
Chu, Yaping;
Takano, Akihiro;
Schwarz, Adam J.;
Yeh, Chien‐Lin;
McQuade, Paul;
Chakrabarty, Paramita;
Kanaan, Nicholas M.;
Quinton, Maria S.;
Simen, Arthur A.;
Kordower, Jeffrey H.;
Morrison, John H.

Publication type:

Article

Pax4 Expression does not Transduce Pancreatic Alpha Cells to Beta Cells.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2015, v. 36, n. 5, p. 1735, doi. 10.1159/000430146

By:

Chen, Ling;
Zhang, Jing;
Zhang, Zhuo;
Chu, Yaping;
Song, Bing;
Cai, Wang

Publication type:

Article

Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates.

Published in:

Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0451-7

By:

Mandel, Ronald J.;
Marmion, David J.;
Kirik, Deniz;
Yaping Chu;
Heindel, Clifford;
McCown, Thomas;
Gray, Steven J.;
Kordower, Jeffrey H.

Publication type:

Article

Sortilin Fragments Deposit at Senile Plaques in Human Cerebrum.

Published in:

Frontiers in Neuroanatomy, 2017, p. 1, doi. 10.3389/fnana.2017.00045

By:

Xia Hu;
Zhao-Lan Hu;
Zheng Li;
Chun-Sheng Ruan;
Wen-Ying Qiu;
Aihua Pan;
Chang-Qi Li;
Yan Cai;
Lu Shen;
Yaping Chu;
Bei-Sha Tang;
Huaibin Cai;
Xin-Fu Zhou;
Chao Ma;
Xiao-Xin Yan

Publication type:

Article

Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys.

Published in:

Annals of Neurology, 2006, v. 60, n. 2, p. 264

By:

Jeffrey H. Kordower;
Nicholas M. Kanaan;
Yaping Chu;
Rangasamy Suresh Babu;
James Stansell;
Brian T. Terpstra;
Caryl E. Sortwell;
Kathy Steece‐Collier;
Timothy J. Collier

Publication type:

Article

Proteasome inhibition and Parkinson's disease modeling.

Published in:

Annals of Neurology, 2006, v. 60, n. 2, p. 260

By:

Jordi Bové;
Chun Zhou;
Vernice Jackson‐Lewis;
Julie Taylor;
Yaping Chu;
Hardy J. Rideout;
Du‐Chu Wu;
Jeffrey H. Kordower;
Leonard Petrucelli;
Serge Przedborski

Publication type:

Article

Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment.

Published in:

Annals of Neurology, 2001, v. 49, n. 2, p. 202, doi. 10.1002/1531-8249(20010201)49:2<202::AID-ANA40>3.0.CO;2-3

By:

Kordower, Jeffrey H.;
Chu, Yaping;
Stebbins, Glenn T.;
DeKosky, Steven T.;
Cochran, Elizabeth J.;
Bennett, David;
Mufson, Elliott J.

Publication type:

Article

A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, n. 5, p. 571, doi. 10.1016/j.jalz.2013.09.004

By:

Rafii, Michael S.;
Baumann, Tiffany L.;
Bakay, Roy A.E.;
Ostrove, Jeffrey M.;
Siffert, Joao;
Fleisher, Adam S.;
Herzog, Christopher D.;
Barba, David;
Pay, Mary;
Salmon, David P.;
Chu, Yaping;
Kordower, Jeffrey H.;
Bishop, Kathie;
Keator, David;
Potkin, Steven;
Bartus, Raymond T.

Publication type:

Article

Detecting Alpha Synuclein Seeding Activity in Formaldehyde-Fixed MSA Patient Tissue by PMCA.

Published in:

Molecular Neurobiology, 2018, v. 55, n. 11, p. 8728, doi. 10.1007/s12035-018-1007-y

By:

Becker, Katelyn;
Wang, Xinhe;
Vander Stel, Kayla;
Chu, Yaping;
Kordower, Jeffrey;
Ma, Jiyan

Publication type:

Article

Transgene Expression, Bioactivity, and Safety of CERE-120 (AAV2-Neurturin) Following Delivery to the Monkey Striatum.

Published in:

Molecular Therapy, 2008, v. 16, n. 10, p. 1737, doi. 10.1038/mt.2008.170

By:

Herzog, Christopher D.;
Dass, Biplob;
Gasmi, Mehdi;
Bakay, Roy;
Stansell, James E.;
Tuszynski, Mark;
Bankiewicz, Krystof;
Er-Yun Chen;
Yaping Chu;
Bishop, Kathie;
Kordower, Jeffrey H.;
Bartus, Raymond T.

Publication type:

Article

β-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation.

Published in:

European Journal of Neuroscience, 2010, v. 32, n. 7, p. 1223, doi. 10.1111/j.1460-9568.2010.07376.x

By:

Cai, Yan;
Xiong, Kun;
Zhang, Xue‐Mei;
Cai, Huaibin;
Luo, Xue‐Gang;
Feng, Jia‐Chun;
Clough, Richard W.;
Struble, Robert G.;
Patrylo, Peter R.;
Chu, Yaping;
Kordower, Jeffrey H.;
Yan, Xiao‐Xin

Publication type:

Article

Parkinsonian monkeys with prior levodopa-induced dyskinesias followed by fetal dopamine precursor grafts do not display graft-induced dyskinesias.

Published in:

Journal of Comparative Neurology, 2017, v. 525, n. 3, p. 498, doi. 10.1002/cne.24081

By:

Kordower, Jeffrey H.;
Vinuela, Angel;
Chu, Yaping;
Isacson, Ole;
Redmond, D. Eugene

Publication type:

Article

Post‐Mortem Studies of Neurturin Gene Therapy for Parkinson's Disease: Two Subjects with 10 Years CERE120 Delivery.

Published in:

Movement Disorders, 2023, v. 38, n. 9, p. 1728, doi. 10.1002/mds.29518

By:

Chu, Yaping;
Kordower, Jeffrey H.

Publication type:

Article

Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis.

Published in:

NPJ Parkinson's Disease, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41531-023-00491-3

By:

Killinger, Bryan A.;
Mercado, Gabriela;
Choi, Solji;
Tittle, Tyler;
Chu, Yaping;
Brundin, Patrik;
Kordower, Jeffrey H.

Publication type:

Article

Continuous DOPA synthesis from a single AAV: dosing and efficacy in models of Parkinson's disease.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep02157

By:

Cederfjäll, Erik;
Nilsson, Nathalie;
Sahin, Gurdal;
Chu, Yaping;
Nikitidou, Elisabeth;
Björklund, Tomas;
Kordower, Jeffrey H.;
Kirik, Deniz

Publication type:

Article

Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer's disease model mice and macaques.

Published in:

Alzheimer's Research & Therapy, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13195-018-0370-2

By:

Zhou, Feng-Qin;
Jiang, Juan;
Griffith, Chelsea M.;
Patrylo, Peter R.;
Cai, Huaibin;
Chu, Yaping;
Yan, Xiao-Xin

Publication type:

Article

Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra.

Published in:

Journal of Comparative Neurology, 2002, v. 450, n. 3, p. 203, doi. 10.1002/cne.10261

By:

Chu, Yaping;
Kompoliti, Katie;
Cochran, Elizabeth J.;
Mufson, Elliott J.;
Kordower, Jeffrey H.

Publication type:

Article

Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease.

Published in:

Journal of Comparative Neurology, 2001, v. 437, n. 3, p. 296, doi. 10.1002/cne.1284

By:

Chu, Yaping;
Cochran, Elizabeth J.;
Bennett, David A.;
Mufson, Elliott J.;
Kordower, Jeffrey H.

Publication type:

Article

Ciliary neurotrophic factor receptor α-immunoreactivity in the monkey central nervous system.

Published in:

Journal of Comparative Neurology, 1997, v. 377, n. 3, p. 365, doi. 10.1002/(SICI)1096-9861(19970120)377:3<365::AID-CNE5>3.0.CO;2-0

By:

Kordower, Jeffrey H.;
Yaping-Chu;
MacLennan, A. John

Publication type:

Article

Lewy body pathology in fetal grafts.

Published in:

Annals of the New York Academy of Sciences, 2010, v. 1184, n. 1, p. 55, doi. 10.1111/j.1749-6632.2009.05229.x

By:

Chu, Yaping;
Kordower, Jeffrey H.

Publication type:

Article

Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins.

Published in:

Acta Neuropathologica, 2017, v. 134, n. 4, p. 629, doi. 10.1007/s00401-017-1722-x

By:

Flavin, William;
Bousset, Luc;
Green, Zachary;
Chu, Yaping;
Skarpathiotis, Stratos;
Chaney, Michael;
Kordower, Jeffrey;
Melki, Ronald;
Campbell, Edward

Publication type:

Article