Works matching DE "CHOLESTEROL hydroxylase"

Results: 303

A review of the putative antiseizure and antiepileptogenic mechanisms of action for soticlestat.

Published in:

Epilepsia (Series 4), 2025, v. 66, n. 5, p. 1394, doi. 10.1111/epi.18287

By:

Kondo, Shinichi;
Murthy, Venkatesha;
Asgharnejad, Mahnaz;
Benitez, Arturo;
Nakashima, Kosuke;
Hawkins, Nicole;
White, H. Steve

Publication type:

Article

Does local sympathetic atrophy contribute to splanchnic vasodilation in portal hypertension?

Published in:

2010

By:

Møller, Søren;
Stauber, Rudolf E.

Publication type:

Editorial

Regulation of vitamin D homeostasis: implications for the immune system.

Published in:

Nutrition Reviews, 2008, v. 66, p. S125, doi. 10.1111/j.1753-4887.2008.00096.x

By:

van Etten, Evelyne;
Stoffels, Katinka;
Gysemans, Conny;
Mathieu, Chantal;
Overbergh, Lut

Publication type:

Article

Laccase treatment of recycled blue dyed paper: physical properties and fiber charge.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2008, v. 35, n. 10, p. 1103, doi. 10.1007/s10295-008-0388-8

By:

Mohandass, Chellandi;
Knutson, Kristina;
Ragauskas, Arthur J.

Publication type:

Article

High‐Fat Feeding Exerts Minimal Effects on Rhythmic mRNA Expression of Clock Genes in Mouse Peripheral Tissues

Published in:

Chronobiology International: The Journal of Biological & Medical Rhythm Research, 2006, v. 23, n. 5, p. 905, doi. 10.1080/07420520600827103

By:

Yanagihara, Hayato;
Ando, Hitoshi;
Hayashi, Yohei;
Obi, Yuri;
Fujimura, Akio

Publication type:

Article

Association of Blood Pressure and Genetic Background With White Matter Lesions in Patients With Mild Cognitive Impairment.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2008, v. 63, n. 5, p. 510, doi. 10.1093/gerona/63.5.510

By:

Galluzzi, Samantha;
Geroldi, Cristina;
Benussi, Luisa;
Ghidoni, Roberta;
Testa, Cristina;
Borsci, Genoveffa;
Bonetti, Matteo;
Manfellotto, Dario;
Romanelli, Giuseppe;
Zulu, Roberto;
Binetti, Giuliano;
Frisoni, Giovanni B.

Publication type:

Article

24S-Hydroxycholesterol and Cerebellar Degeneration: Insights from SCA2.

Published in:

Cerebellum, 2023, v. 22, n. 5, p. 1020, doi. 10.1007/s12311-022-01448-7

By:

Locci, Sara;
Nidiaci, Valentina;
De Stefano, Nicola;
Leoni, Valerio;
Mignarri, Andrea

Publication type:

Article

Calycosin-7-O-β-D-Glucoside Ameliorates Palmitate-Induced Lipid Accumulation in HT22 Cells.

Published in:

Actas Espanolas de Psiquiatria, 2024, v. 52, n. 5, p. 641, doi. 10.62641/aep.v52i5.1723

By:

Yanming Xu;
Dalong Li;
Ao Xue;
Jiaming Gu;
Yifan Ren;
Siyu Zhu;
Xia Lei;
Jianxin Liu;
Jihui Zhao;
Fang Geng;
Ning Zhang

Publication type:

Article

Hepatic Cholesterol-25-Hydroxylase Overexpression Improves Systemic Insulin Sensitivity in Mice.

Published in:

Journal of Diabetes Research, 2017, p. 1, doi. 10.1155/2017/4108768

By:

Noebauer, Britta;
Jais, Alexander;
Todoric, Jelena;
Gossens, Klaus;
Sutterlüty-Fall, Hedwig;
Einwallner, Elisa

Publication type:

Article

Development of a warning model for drug-induced liver injury in the older patients.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1603089

By:

Hu, Qiaozhi;
Li, Xiaoqi;
Zou, Dan;
He, Zhiyao;
Xu, Ting

Publication type:

Article

Metabolic Regulations by lncRNA, miRNA, and ceRNA Under Grass-Fed and Grain-Fed Regimens in Angus Beef Cattle.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2021.579393

By:

Jia, Cunling;
Bai, Ying;
Liu, Jianan;
Cai, Wentao;
Liu, Lei;
He, Yanghua;
Song, Jiuzhou

Publication type:

Article

Effects of acaricides on the activities of monooxygenases in bovine liver microsomes.

Published in:

Journal of Veterinary Pharmacology & Therapeutics, 2023, v. 46, n. 6, p. 375, doi. 10.1111/jvp.13395

By:

Larsen, Karen;
Ichinose, Paula;
Fernández‐San Juan, Rocío;
Lifschitz, Adrián;
Virkel, Guillermo

Publication type:

Article

Modulation of Vascular O2 Responses by Cytochrome 450-4A ω-Hydroxylase Metabolites In Dahl Salt-Sensitive Rats.

Published in:

Microcirculation, 2009, v. 16, n. 4, p. 345, doi. 10.1080/10739680802698007

By:

Jingli Wang;
Schmidt, James R.;
Roman, Richard J.;
Anjaiah, Siddam;
Falck, John R.;
Lombard, Julian H.

Publication type:

Article

Scutellarin regulates osteoarthritis in vitro by inhibiting the PI3K/AKT/mTOR signaling pathway.

Published in:

Molecular Medicine Reports, 2021, v. 23, n. 1, p. N.PAG

By:

Ju, Shao-Hua;
Tan, Li-Rong;
Liu, Pan-Wang;
Tan, You-Li;
Zhang, Yuan-Ting;
Li, Xiao-Hong;
Wang, Ming-Jian;
He, Ben-Xiang

Publication type:

Article

The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington's disease.

Published in:

BMC Research Notes, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s13104-020-05053-x

By:

Nóbrega, Clévio;
Conceição, André;
Costa, Rafael G.;
Koppenol, Rebekah;
Sequeira, Raquel L.;
Nunes, Ricardo;
Carmo-Silva, Sara;
Marcelo, Adriana;
Matos, Carlos A.;
Betuing, Sandrine;
Caboche, Jocelyne;
Cartier, Nathalie;
Alves, Sandro

Publication type:

Article

Effect of a freeze-dried coffee solution in a high-fat diet-induced obesity model in rats: Impact on inflammatory response, lipid profile, and gut microbiota.

Published in:

PLoS ONE, 2022, v. 17, n. 1, p. 1, doi. 10.1371/journal.pone.0262270

By:

Cavalcanti, Marilia Hermes;
Roseira, João Paulo Santos;
Leandro, Eliana dos Santos;
Arruda, Sandra Fernandes

Publication type:

Article

The substantia nigra pars compacta of the Göttingen minipig: an anatomical and stereological study.

Published in:

Brain Structure & Function, 2008, v. 213, n. 4/5, p. 481, doi. 10.1007/s00429-009-0217-5

By:

Nielsen, Mette;
Sørensen, Jens;
Bjarkam, Carsten

Publication type:

Article

Evaluation of Antidiabetic Activity of Vitis pedata in Alloxan Induced Diabetic Rats.

Published in:

Indian Journal of Pharmaceutical Sciences, 2022, v. 84, n. 3, p. 631

By:

BHATTACHARYA, JOYEETA;
ATA, S.;
CHAKRABARTY, S.;
JHA, S. K.;
ROY, P.

Publication type:

Article

PHD3 regulates differentiation, tumour growth and angiogenesis in pancreatic cancer.

Published in:

2010

By:

Su, Y.;
Loos, M.;
Giese, N.;
Hines, O. J.;
Diebold, I.;
Görlach, A.;
Metzen, E.;
Pastorekova, S.;
Friess, H.;
Büchler, P.;
Görlach, A;
Büchler, P

Publication type:

journal article

Role of cholesterol in modulating brain hyperexcitability.

Published in:

Epilepsia (Series 4), 2025, v. 66, n. 1, p. 33, doi. 10.1111/epi.18174

By:

Wheless, James W.;
Rho, Jong M.

Publication type:

Article

A phase 2, randomized, double‐blind, placebo‐controlled study to evaluate the efficacy and safety of soticlestat as adjunctive therapy in pediatric patients with Dravet syndrome or Lennox–Gastaut syndrome (ELEKTRA).

Published in:

Epilepsia (Series 4), 2022, v. 63, n. 10, p. 2671, doi. 10.1111/epi.17367

By:

Hahn, Cecil D.;
Jiang, Yuwu;
Villanueva, Vicente;
Zolnowska, Marta;
Arkilo, Dimitrios;
Hsiao, Samuel;
Asgharnejad, Mahnaz;
Dlugos, Dennis

Publication type:

Article

Anticonvulsive properties of soticlestat, a novel cholesterol 24‐hydroxylase inhibitor.

Published in:

Epilepsia (Series 4), 2022, v. 63, n. 6, p. 1580, doi. 10.1111/epi.17232

By:

Nishi, Toshiya;
Metcalf, Cameron S.;
Fujimoto, Shinji;
Hasegawa, Shigeo;
Miyamoto, Maki;
Sunahara, Eiji;
Watanabe, Sayuri;
Kondo, Shinichi;
White, H. Steve

Publication type:

Article

Soticlestat, a novel cholesterol 24‐hydroxylase inhibitor, reduces seizures and premature death in Dravet syndrome mice.

Published in:

Epilepsia (Series 4), 2021, v. 62, n. 11, p. 2845, doi. 10.1111/epi.17062

By:

Hawkins, Nicole A.;
Jurado, Manuel;
Thaxton, Tyler T.;
Duarte, Samantha E.;
Barse, Levi;
Tatsukawa, Tetsuya;
Yamakawa, Kazuhiro;
Nishi, Toshiya;
Kondo, Shinichi;
Miyamoto, Maki;
Abrahams, Brett S.;
During, Matthew J.;
Kearney, Jennifer A.

Publication type:

Article

Linkage disequilibrium blocks, haplotype structure, and htSNPs of human CYP7A1 gene.

Published in:

BMC Genetics, 2006, v. 7, p. 29, doi. 10.1186/1471-2156-7-29

By:

Nakamoto, Kaori;
Wang, Shuang;
Jenison, Robert D;
Guo, Grace L;
Klaassen, Curtis D;
Wan, Yu-Jui Yvonne;
Zhong, Xiao-bo

Publication type:

Article

Genetic polymorphism of cholesterol 7α-hydroxylase (CYP7A1) and colorectal adenomas: Self Defense Forces Health Study.

Published in:

Cancer Science, 2006, v. 97, n. 5, p. 406, doi. 10.1111/j.1349-7006.2006.00182.x

By:

Tabata, Shinji;
Yin, Guang;
Ogawa, Shinsaku;
Yamaguchi, Keizo;
Mineshita, Masamichi;
Kono, Suminori

Publication type:

Article

The expression of 25-hydroxyvitamin D-1 - hydroxylase and megalin in murine embryonic kidney.

Published in:

Asia Pacific Journal of Clinical Nutrition, 2002, v. 11, p. S35

By:

Ozono, Keiichi;
Yamagata, Masayo;
Michigami, Toshimi;
Seino, Yoshiki

Publication type:

Article

Brain injury induces cholesterol 24-hydroxylase (Cyp46) expression in glial cells in a time-dependent manner.

Published in:

Histochemistry & Cell Biology, 2010, v. 134, n. 2, p. 159, doi. 10.1007/s00418-010-0718-6

By:

Smiljanic, Kosara;
Lavrnja, Irena;
Mladenovic Djordjevic, Aleksandra;
Ruzdijic, Sabera;
Stojiljkovic, Mirjana;
Pekovic, Sanja;
Kanazir, Selma

Publication type:

Article

Effects of Acute, Repeated and Chronic Variable Stress on In Vivo Tyrosine Hydroxylase Activity and on α 2 -adrenoceptor Sensitivity in the Rat Brain.

Published in:

Stress: The International Journal on the Biology of Stress, 2003, v. 6, n. 4, p. 281, doi. 10.1080/10253890310001603648

By:

Prieto, Mónica;
Gómez, Francisco M.;
Giralt, M. Teresa

Publication type:

Article

基于肠 FXR‐FGF15 通路探讨沙棘熊果酸对酒精性肝损伤小鼠的影响.

Published in:

Food Research & Development, 2025, v. 46, n. 2, p. 9, doi. 10.12161/j.issn.1005‐6521.2025.02.002

By:

李楠;
赵雪;
郭少龙;
张文龙;
戈娜;
李智;
林琰

Publication type:

Article

Rat mesenchymal stem cells increase tyrosine hydroxylase expression and dopamine content in ventral mesencephalic cells in vitro

Published in:

Cell Biology International, 2008, v. 32, n. 11, p. 1433, doi. 10.1016/j.cellbi.2008.08.014

By:

Jin, Guang-Zhen;
Cho, Su-Jin;
Choi, Eu-Gene;
Lee, Young-S.;
Yu, Xian-Feng;
Choi, Kap-Seong;
Yee, Sung-Tae;
Jeon, Jin-Tae;
Kim, Myeong-Ok;
Kong, Il-Keun

Publication type:

Article

Decreased protein and gene expression of hepatic cholesterol 7a-hydroxylase associated with dilated endoplasmic reticulum in chronic hypothyroid rats.

Published in:

Pathology International, 2009, v. 59, n. 10, p. 729, doi. 10.1111/j.1440-1827.2009.02435.x

By:

Xinli Zhou;
Yong Han;
Jia Liu;
Ling Gao;
Jiajun Zhao

Publication type:

Article

Impact of Liver Inflammation on Bile Acid Side Chain Shortening and Amidation.

Published in:

Cells (2073-4409), 2022, v. 11, n. 24, p. 3983, doi. 10.3390/cells11243983

By:

Alonso-Peña, Marta;
Espinosa-Escudero, Ricardo;
Hermanns, Heike M.;
Briz, Oscar;
Herranz, Jose M.;
Garcia-Ruiz, Carmen;
Fernandez-Checa, Jose C.;
Juamperez, Javier;
Avila, Matias;
Argemi, Josepmaria;
Bataller, Ramon;
Crespo, Javier;
Monte, Maria J.;
Geier, Andreas;
Herraez, Elisa;
Marin, Jose J. G.

Publication type:

Article

Oxysterols in the Immune Response to Bacterial and Viral Infections.

Published in:

Cells (2073-4409), 2022, v. 11, n. 2, p. 201, doi. 10.3390/cells11020201

By:

Foo, Cheng Xiang;
Bartlett, Stacey;
Ronacher, Katharina

Publication type:

Article

A Role for ER-Beta in the Effects of Low-Density Lipoprotein Cholesterol and 27-Hydroxycholesterol on Breast Cancer Progression: Involvement of the IGF Signalling Pathway?

Published in:

Cells (2073-4409), 2022, v. 11, n. 1, p. 94, doi. 10.3390/cells11010094

By:

Mashat, Reham M.;
Zielinska, Hanna A.;
Holly, Jeff M. P.;
Perks, Claire M.

Publication type:

Article

Impaired Bile Acid Metabolism and Gut Dysbiosis in Mice Lacking Lysosomal Acid Lipase.

Published in:

Cells (2073-4409), 2021, v. 10, n. 10, p. 2619, doi. 10.3390/cells10102619

By:

Sachdev, Vinay;
Duta-Mare, Madalina;
Korbelius, Melanie;
Vujić, Nemanja;
Leopold, Christina;
Freark de Boer, Jan;
Rainer, Silvia;
Fickert, Peter;
Kolb, Dagmar;
Kuipers, Folkert;
Radovic, Branislav;
Gorkiewicz, Gregor;
Kratky, Dagmar

Publication type:

Article

From Enzyme to Preparative Cascade Reactions with Immobilized Enzymes: Tuning Fe(II)/α-Ketoglutarate-Dependent Lysine Hydroxylases for Application in Biotransformations.

Published in:

Catalysts (2073-4344), 2022, v. 12, n. 4, p. 354, doi. 10.3390/catal12040354

By:

Seide, Selina;
Arnold, Lilia;
Wetzels, Solange;
Bregu, Mariela;
Gätgens, Jochem;
Pohl, Martina

Publication type:

Article

Effects of Lactobacillus fermentum CQPC04 on Lipid Reduction in C57BL/6J Mice.

Published in:

Frontiers in Microbiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.573586

By:

Yi, Ruokun;
Tan, Fang;
Zhou, Xianrong;
Mu, Jianfei;
Li, Lin;
Du, Xiping;
Yang, Zhennai;
Zhao, Xin

Publication type:

Article

Localization of tabersonine 16-hydroxylase and 16-OH tabersonine-16- O-methyltransferase to leaf epidermal cells defines them as a major site of precursor biosynthesis in the vindoline pathway in Catharanthus roseus.

Published in:

Plant Journal, 2005, v. 44, n. 4, p. 581, doi. 10.1111/j.1365-313X.2005.02557.x

By:

Murata, Jun;
Luca, Vincenzo De

Publication type:

Article

The chimeric CYP21P/CYP21 gene and 21-hydroxylase deficiency.

Published in:

Journal of Human Genetics, 2004, v. 49, n. 2, p. 65, doi. 10.1007/s10038-003-0115-2

By:

Hsien-Hsiung Lee

Publication type:

Article

ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28769-9

By:

Zhao, Yuanyuan;
Hu, Di;
Wang, Rihua;
Sun, Xiaoyan;
Ropelewski, Philip;
Hubler, Zita;
Lundberg, Kathleen;
Wang, Quanqiu;
Adams, Drew J.;
Xu, Rong;
Qi, Xin

Publication type:

Article

NADPH-dependent coenzyme Q reductase is the main enzyme responsible for the reduction of non-mitochondrial CoQ in cells.

Published in:

Biofactors, 2008, v. 32, n. 1-4, p. 59, doi. 10.1002/biof.5520320108

By:

Takahashi, Takayuki;
Okuno, Masaaki;
Okamoto, Tadashi;
Kishi, Takeo

Publication type:

Article

Modulation of Brain Cholesterol Metabolism through CYP46A1 Overexpression for Rett Syndrome.

Published in:

Pharmaceutics, 2024, v. 16, n. 6, p. 756, doi. 10.3390/pharmaceutics16060756

By:

Audouard, Emilie;
Khefif, Nicolas;
Gillet-Legrand, Béatrix;
Nobilleau, Fanny;
Bouazizi, Ouafa;
Stanga, Serena;
Despres, Gaëtan;
Alves, Sandro;
Lamazière, Antonin;
Cartier, Nathalie;
Piguet, Françoise

Publication type:

Article

Prevention of Milk fever: Nutritional Approach.

Published in:

Veterinary World, 2011, v. 4, n. 6, p. 278, doi. 10.5455/vetworld.4.278

By:

Patel, V. R.;
Kansara, J. D.;
Patel, B. B.;
Patel, P. B.;
Patel, S. B.

Publication type:

Article

Modulating effect of the A-278C promoter polymorphism in the cholesterol 7alpha-hydroxylase gene on serum lipid levels in normolipidaemic and hypertriglyceridaemic individuals.

Published in:

European Journal of Human Genetics, 2004, v. 12, n. 11, p. 935, doi. 10.1038/sj.ejhg.5201236

By:

Hofman, M K;
Groenendijk, M;
Verkuijlen, P J J H;
Jonkers, I J A M;
Mohrschladt, M F;
Smelt, A H M;
Princen, H M G

Publication type:

Article

A Mutation Analysis of the Phenylalanine Hydroxylase ( PAH) Gene in the Israeli Population.

Published in:

Annals of Human Genetics, 2008, v. 72, n. 3, p. 305, doi. 10.1111/j.1469-1809.2007.00425.x

By:

Bercovich, D.;
Elimelech, A.;
Yardeni, T.;
Korem, S.;
Zlotogora, J.;
Gal, N.;
Goldstein, N.;
Vilensky, B.;
Segev, R.;
Avraham, S.;
Loewenthal, R.;
Schwartz, G.;
Anikster, Y.

Publication type:

Article

Design of Tripeptides as a Competitive Inhibitor for HMG-CoA Reductase.

Published in:

International Journal of Peptide Research & Therapeutics, 2021, v. 27, n. 3, p. 1923, doi. 10.1007/s10989-021-10221-z

By:

Pak, Valeriy V.;
Kwon, Dae Yong;
Khojimatov, Olim K.;
Pak, Aleksandr V.;
Sagdullaev, Shomansur Sh.

Publication type:

Article

Rat Brain Synaptic Vesicles are Devoid of Mg2+-ATPase Activity and Contain β-Amyloid Precursor Protein.

Published in:

Journal of Biochemistry, 2007, v. 141, n. 1, p. 93, doi. 10.1093/jb/mvm006

By:

Tsudzuki, Toshihiro

Publication type:

Article

Molecular Mechanism for Pterin-Mediated Inactivation of Tyrosine Hydroxylase: Formation of Insoluble Aggregates of Tyrosine Hydroxylase.

Published in:

Journal of Biochemistry, 2006, v. 139, n. 4, p. 625, doi. 10.1093/jb/mvj073

By:

Urano, Fumi;
Hayashi, Nobuhiro;
Arisaka, Fumio;
Kurita, Hideki;
Murata, Shizuaki;
Ichinose, Hiroshi

Publication type:

Article

The Post-Translational Synthesis of a Polyamine-Derived Amino Acid, Hypusine, in the Eukaryotic Translation Initiation Factor 5A (eIF5A).

Published in:

Journal of Biochemistry, 2006, v. 139, n. 2, p. 161, doi. 10.1093/jb/mvj034

By:

Myung Hee Park

Publication type:

Article

Effects of new 17α-hydroxylase/C<sub>17,20</sub>-lyase inhibitors on LNCaP prostate cancer cell growth in vitro and in vivo.

Published in:

British Journal of Cancer, 1999, v. 81, n. 4, p. 622, doi. 10.1038/sj.bjc.6690739

By:

Grigoryev, D N;
Long, B J;
Nnane, I P;
Njar, V C O;
Liu, Y;
Brodie, A M H

Publication type:

Article