Works matching AU Mak, Jeffrey Y. W.

Results: 32

Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 31, p. 1, doi. 10.1002/anie.202400632

By:

Mak, Jeffrey Y. W.;
Rivero, Ryan J. D.;
Hoang, Huy N.;
Lim, Xin Yi;
Deng, Jieru;
McWilliam, Hamish E. G.;
Villadangos, Jose A.;
McCluskey, James;
Corbett, Alexandra J.;
Fairlie, David P.

Publication type:

Article

Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 29, p. 1, doi. 10.1002/anie.202203995

By:

de Araujo, Aline D.;
Hoang, Huy N.;
Lim, Junxian;
Mak, Jeffrey Y. W.;
Fairlie, David P.

Publication type:

Article

Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages.

Published in:

PLoS Pathogens, 2022, v. 18, n. 1, p. 1, doi. 10.1371/journal.ppat.1010166

By:

Tran, Thao Thanh;
Mathmann, Carmen D.;
Gatica-Andrades, Marcela;
Rollo, Rachel F.;
Oelker, Melanie;
Ljungberg, Johanna K.;
Nguyen, Tam T. K.;
Zamoshnikova, Alina;
Kummari, Lalith K.;
Wyer, Orry J. K.;
Irvine, Katharine M.;
Melo-Bolívar, Javier;
Gross, Annette;
Brown, Darren;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Hansford, Karl A.;
Cooper, Matthew A.;
Giri, Rabina;
Schreiber, Veronika

Publication type:

Article

Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli.

Published in:

PLoS Biology, 2020, v. 18, n. 6, p. 1, doi. 10.1371/journal.pbio.3000644

By:

Boulouis, Caroline;
Sia, Wan Rong;
Gulam, Muhammad Yaaseen;
Teo, Jocelyn Qi Min;
Png, Yi Tian;
Phan, Thanh Kha;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Poon, Ivan K. H.;
Koh, Tse Hsien;
Bergman, Peter;
Lim, Chwee Ming;
Wang, Lin-Fa;
Kwa, Andrea Lay Hoon;
Sandberg, Johan K.;
Leeansyah, Edwin

Publication type:

Article

Human MAIT cells respond to and suppress HIV-1.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.50324

By:

Phetsouphanh, Chansavath;
Phalora, Prabhjeet;
Hackstein, Carl-Philipp;
Thornhill, John;
Munier, C. Mee Ling;
Meyerowitz, Jodi;
Murray, Lyle;
VanVuuren, Cloete;
Goedhals, Dominique;
Drexhage, Linnea;
Moore, Rebecca;
Sattentau, Quentin J.;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Fidler, Sarah;
Kelleher, Anthony D.;
Frater, John;
Klenerman, Paul

Publication type:

Article

Artificially induced MAIT cells inhibit M. bovis BCG but not M. tuberculosis during in vivo pulmonary infection.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-70615-9

By:

Yu, Huifeng;
Yang, Amy;
Derrick, Steven;
Mak, Jeffrey Y. W.;
Liu, Ligong;
Fairlie, David P.;
Cowley, Siobhan

Publication type:

Article

MAIT cells protect against pulmonary Legionella longbeachae infection.

Published in:

Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-05202-8

By:

Huimeng Wang;
D'Souza, Criselle;
Xin Yi Lim;
Kostenko, Lyudmila;
Pediongco, Troi J.;
Eckle, Sidonia B. G.;
Meehan, Bronwyn S.;
Mai Shi;
Wang, Nancy;
Shihan Li;
Ligong Liu;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Yoichiro Iwakura;
Gunnersen, Jennifer M.;
Stent, Andrew W.;
Godfrey, Dale I.;
Rossjohn, Jamie;
Westall, Glen P.;
Kjer-Nielsen, Lars

Publication type:

Article

Stereoelectronic Effects on Dienophile Separation Influence the Diels-Alder Synthesis of Molecular Clefts.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 45, p. 6793, doi. 10.1002/ejoc.201701319

By:

Stoermer, Martin J.;
Wickramasinghe, Wasantha A.;
Byriel, Karl A.;
Hockless, David C. R.;
Skelton, Brian W.;
Sobolev, Alexandre N.;
White, Allan H.;
Mak, Jeffrey Y. W.;
Fairlie, David P.

Publication type:

Article

Total Synthesis of (-)-Neovibsanin G and (-)-14- epi-Neovibsanin G: Towards the Synthesis of 15- O-Methylneovibsanin F and 14- epi-15- O-Methylneovibsanin F.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 10, p. 2001, doi. 10.1002/ejoc.201101796

By:

Mak, Jeffrey Y. W.;
Williams, Craig M.

Publication type:

Article

Histone deacetylase 7: a signalling hub controlling development, inflammation, metabolism and disease.

Published in:

FEBS Journal, 2023, v. 290, n. 11, p. 2805, doi. 10.1111/febs.16437

By:

Wang, Yizhuo;
Abrol, Rishika;
Mak, Jeffrey Y. W.;
Das Gupta, Kaustav;
Ramnath, Divya;
Karunakaran, Denuja;
Fairlie, David P.;
Sweet, Matthew J.

Publication type:

Article

CXCL16 Stimulates Antigen-Induced MAIT Cell Accumulation but Trafficking During Lung Infection Is CXCR6-Independent.

Published in:

Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.01773

By:

Yu, Huifeng;
Yang, Amy;
Liu, Ligong;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Cowley, Siobhan

Publication type:

Article

Natural Products with Anti-Bredt and Bridgehead Double Bonds.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 50, p. 13664, doi. 10.1002/anie.201400932

By:

Mak, Jeffrey Y. W.;
Pouwer, Rebecca H.;
Williams, Craig M.

Publication type:

Article

Naturstoffe mit Anti-Bredt- und Brückenkopf-Doppelbindung.

Published in:

Angewandte Chemie, 2014, v. 126, n. 50, p. 13882, doi. 10.1002/ange.201400932

By:

Mak, Jeffrey Y. W.;
Pouwer, Rebecca H.;
Williams, Craig M.

Publication type:

Article

T-cell activation by transitory neo-antigens derived from distinct microbial pathways.

Published in:

Nature, 2014, v. 509, n. 7500, p. 361, doi. 10.1038/nature13160

By:

Corbett, Alexandra J.;
Eckle, Sidonia B. G.;
Birkinshaw, Richard W.;
Liu, Ligong;
Patel, Onisha;
Mahony, Jennifer;
Chen, Zhenjun;
Reantragoon, Rangsima;
Meehan, Bronwyn;
Cao, Hanwei;
Williamson, Nicholas A.;
Strugnell, Richard A.;
Van Sinderen, Douwe;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Kjer-Nielsen, Lars;
Rossjohn, Jamie;
McCluskey, James

Publication type:

Article

Varicella Zoster Virus disrupts MAIT cell polyfunctional effector responses.

Published in:

PLoS Pathogens, 2024, v. 20, n. 8, p. 1, doi. 10.1371/journal.ppat.1012372

By:

Purohit, Shivam. K.;
Stern, Lauren;
Corbett, Alexandra J.;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Slobedman, Barry;
Abendroth, Allison

Publication type:

Article

MAIT cell plasticity enables functional adaptation that drives antibacterial immune protection.

Published in:

Science Immunology, 2024, v. 9, n. 102, p. 1, doi. 10.1126/sciimmunol.adp9841

By:

Wang, Huimeng;
Souter, Michael N. T.;
de Lima Moreira, Marcela;
Li, Shihan;
Zhou, Yuchen;
Nelson, Adam G.;
Yu, Jinhan;
Meehan, Lucy J.;
Meehan, Bronwyn S.;
Eckle, Sidonia B. G.;
Lee, Hyun Jae;
Schröder, Jan;
Haque, Ashraful;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
McCluskey, James;
Wang, Zhongfang;
Chen, Zhenjun;
Corbett, Alexandra J.

Publication type:

Article

Sulfated bile acid is a host-derived ligand for MAIT cells.

Published in:

Science Immunology, 2024, v. 9, n. 91, p. 1, doi. 10.1126/sciimmunol.ade6924

By:

Ito, Emi;
Inuki, Shinsuke;
Izumi, Yoshihiro;
Takahashi, Masatomo;
Dambayashi, Yuki;
Ciacchi, Lisa;
Awad, Wael;
Takeyama, Ami;
Shibata, Kensuke;
Mori, Shotaro;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Bamba, Takeshi;
Ishikawa, Eri;
Nagae, Masamichi;
Rossjohn, Jamie;
Yamasaki, Sho

Publication type:

Article

Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1.

Published in:

Science Immunology, 2020, v. 5, n. 49, p. 1, doi. 10.1126/sciimmunol.abc9492

By:

Howson, Lauren J.;
Awad, Wael;
von Borstel, Anouk;
Lim, Hui Jing;
McWilliam, Hamish E. G.;
Sandoval-Romero, Maria L.;
Majumdar, Shamik;
Hamzeh, Abdul Rezzak;
Andrews, Thomas D.;
McDermott, David H.;
Murphy, Philip M.;
Le Nours, Jérôme;
Mak, Jeffrey Y. W.;
Liu, Ligong;
Fairlie, David P.;
McCluskey, James;
Villadangos, Jose A.;
Cook, Matthew C.;
Turner, Stephen J.;
Davey, Martin S.

Publication type:

Article

IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection.

Published in:

Science Immunology, 2019, v. 4, n. 41, p. 1, doi. 10.1126/sciimmunol.aaw0402

By:

Huimeng Wang;
Kjer-Nielsen, Lars;
Mai Shi;
D’Souza, Criselle;
Pediongco, Troi J.;
Hanwei Cao;
Kostenko, Lyudmila;
Xin Yi Lim;
Eckle, Sidonia B. G.;
Meehan, Bronwyn S.;
Tianyuan Zhu;
Bingjie Wang;
Zhe Zhao;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Teng, Michele W. L.;
Rossjohn, Jamie;
Di Yu;
de St Groth, Barbara Fazekas;
Lovrecz, George

Publication type:

Article

An overview on the identification of MAIT cell antigens.

Published in:

Immunology & Cell Biology, 2018, v. 96, n. 6, p. 573, doi. 10.1111/imcb.12057

By:

Kjer‐Nielsen, Lars;
Corbett, Alexandra J.;
Chen, Zhenjun;
Liu, Ligong;
Mak, Jeffrey Y. W.;
Godfrey, Dale I.;
Rossjohn, Jamie;
Fairlie, David P.;
McCluskey, James;
Eckle, Sidonia B. G.

Publication type:

Article

Differential location of NKT and MAIT cells within lymphoid tissue.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07704-4

By:

Johnson, Darryl N.;
Ruan, Zheng;
Petley, Emma V.;
Devi, Sapna;
Holz, Lauren E.;
Uldrich, Adam P.;
Mak, Jeffrey Y. W.;
Hor, Jyh Liang;
Mueller, Scott N.;
McCluskey, James;
Fairlie, David P.;
Darcy, Phillip K.;
Beavis, Paul A.;
Heath, William R.;
Godfrey, Dale I.

Publication type:

Article

Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis.

Published in:

Angewandte Chemie, 2024, v. 136, n. 31, p. 1, doi. 10.1002/ange.202400632

By:

Mak, Jeffrey Y. W.;
Rivero, Ryan J. D.;
Hoang, Huy N.;
Lim, Xin Yi;
Deng, Jieru;
McWilliam, Hamish E. G.;
Villadangos, Jose A.;
McCluskey, James;
Corbett, Alexandra J.;
Fairlie, David P.

Publication type:

Article

Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides.

Published in:

Angewandte Chemie, 2022, v. 134, n. 29, p. 1, doi. 10.1002/ange.202203995

By:

de Araujo, Aline D.;
Hoang, Huy N.;
Lim, Junxian;
Mak, Jeffrey Y. W.;
Fairlie, David P.

Publication type:

Article

A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells.

Published in:

Journal of Cell Biology, 2022, v. 221, n. 12, p. 1, doi. 10.1083/jcb.202110125

By:

Hui Jing Lim;
Wubben, Jacinta M.;
Garcia, Cristian Pinero;
Cruz-Gomez, Sebastian;
Deng, Jieru;
Mak, Jeffrey Y. W.;
Hachani, Abderrahman;
Anderson, Regan J.;
Painter, Gavin F.;
Goyette, Jesse;
Amarasinghe, Shanika L.;
Ritchie, Matthew E.;
Roquilly, Antoine;
Fairlie, David P.;
Gaus, Katharina;
Rossjohn, Jamie;
Villadangos, Jose A.;
McWilliam, Hamish E. G.

Publication type:

Article

Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells.

Published in:

Nature Communications, 2017, v. 8, n. 3, p. 14599, doi. 10.1038/ncomms14599

By:

Mak, Jeffrey Y. W.;
Xu, Weijun;
Reid, Robert C.;
Corbett, Alexandra J.;
Meehan, Bronwyn S.;
Wang, Huimeng;
Chen, Zhenjun;
Rossjohn, Jamie;
McCluskey, James;
Liu, Ligong;
Fairlie, David P.

Publication type:

Article

Synthetic 5-amino-6-Dribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1109759

By:

Nelson, Adam G.;
Huimeng Wang;
Dewar, Phoebe M.;
Eddy, Eleanor M.;
Songyi Li;
Xin Yi Lim;
Patton, Timothy;
Yuchen Zhou;
Pediongco, Troi J.;
Meehan, Lucy J.;
Meehan, Bronwyn S.;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Stent, Andrew W.;
Kjer-Nielsen, Lars;
McCluskey, James;
Eckle, Sidonia B. G.;
Corbett, Alexandra J.;
Souter, Michael N. T.;
Zhenjun Chen

Publication type:

Article

Computer Modelling and Synthesis of Deoxy and Monohydroxy Analogues of a Ribitylaminouracil Bacterial Metabolite that Potently Activates Human T Cells.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 68, p. 15594, doi. 10.1002/chem.201903732

By:

Ler, Geraldine J. M.;
Xu, Weijun;
Mak, Jeffrey Y. W.;
Liu, Ligong;
Bernhardt, Paul V.;
Fairlie, David P.

Publication type:

Article

Determination of Sample Concentrations by PULCON NMR Spectroscopy.

Published in:

Australian Journal of Chemistry, 2022, v. 75, n. 2, p. 160, doi. 10.1071/CH21149

By:

Mak, Jeffrey Y. W.

Publication type:

Article

Identification and Phenotype of MAIT Cells in Cattle and Their Response to Bacterial Infections.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.627173

By:

Edmans, Matthew D.;
Connelley, Timothy K.;
Jayaraman, Siddharth;
Vrettou, Christina;
Vordermeier, Martin;
Mak, Jeffrey Y. W.;
Liu, Ligong;
Fairlie, David P.;
Maze, Emmanuel Atangana;
Chrun, Tiphany;
Klenerman, Paul;
Eckle, Sidonia B. G.;
Tchilian, Elma;
Benedictus, Lindert

Publication type:

Article

MAIT cells regulate NK cell-mediated tumor immunity.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25009-4

By:

Petley, Emma V.;
Koay, Hui-Fern;
Henderson, Melissa A.;
Sek, Kevin;
Todd, Kirsten L.;
Keam, Simon P.;
Lai, Junyun;
House, Imran G.;
Li, Jasmine;
Zethoven, Magnus;
Chen, Amanda X. Y.;
Oliver, Amanda J.;
Michie, Jessica;
Freeman, Andrew J.;
Giuffrida, Lauren;
Chan, Jack D.;
Pizzolla, Angela;
Mak, Jeffrey Y. W.;
McCulloch, Timothy R.;
Souza-Fonseca-Guimaraes, Fernando

Publication type:

Article

Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24570-2

By:

Zhao, Zhe;
Wang, Huimeng;
Shi, Mai;
Zhu, Tianyuan;
Pediongco, Troi;
Lim, Xin Yi;
Meehan, Bronwyn S.;
Nelson, Adam G.;
Fairlie, David P.;
Mak, Jeffrey Y. W.;
Eckle, Sidonia B. G.;
de Lima Moreira, Marcela;
Tumpach, Carolin;
Bramhall, Michael;
Williams, Cameron G.;
Lee, Hyun Jae;
Haque, Ashraful;
Evrard, Maximilien;
Rossjohn, Jamie;
McCluskey, James

Publication type:

Article

Recipient mucosal-associated invariant T cells control GVHD within the colon.

Published in:

2018

By:

Varelias, Antiopi;
Bunting, Mark D.;
Ormerod, Kate L.;
Koyama, Motoko;
Olver, Stuart D.;
Straube, Jasmin;
Kuns, Rachel D.;
Robb, Renee J.;
Henden, Andrea S.;
Cooper, Leanne;
Lachner, Nancy;
Gartlan, Kate H.;
Lantz, Olivier;
Kjer-Nielsen, Lars;
Mak, Jeffrey Y. W.;
Fairlie, David P.;
Clouston, Andrew D.;
McCluskey, James;
Rossjohn, Jamie;
Lane, Steven W.

Publication type:

journal article