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Loss of AXIN1 drives acquired resistance to WNT pathway blockade in colorectal cancer cells carrying RSPO3 fusions.
- Published in:
- EMBO Molecular Medicine, 2017, v. 9, n. 3, p. 293, doi. 10.15252/emmm.201606773
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- Publication type:
- Article
VEGF blockade enhances the antitumor effect of BRAF<sup>V</sup><sup>600E</sup> inhibition.
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- EMBO Molecular Medicine, 2017, v. 9, n. 2, p. 219, doi. 10.15252/emmm.201505774
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- Publication type:
- Article
Prospective patient stratification into robust cancer‐cell intrinsic subtypes from colorectal cancer biopsies.
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- Journal of Pathology, 2018, v. 245, n. 1, p. 19, doi. 10.1002/path.5051
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- Publication type:
- Article
A New Transgenic Mouse Model of Heart Failure and Cardiac Cachexia Raised by Sustained Activation of Met Tyrosine Kinase in the Heart.
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- BioMed Research International, 2016, v. 2016, p. 1, doi. 10.1155/2016/9549036
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- Publication type:
- Article
Biochemical and immunological properties of the human carcinoma antigen car-5 defined by the monoclonal antibody BD-5.
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- International Journal of Cancer, 1989, v. 44, n. 1, p. 67, doi. 10.1002/ijc.2910440113
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- Publication type:
- Article
A non-dividing cell population with high pyruvate dehydrogenase kinase activity regulates metabolic heterogeneity and tumorigenesis in the intestine.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29085-y
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- Publication type:
- Article
Reverse signaling by semaphorin 4C elicits SMAD1/5- and ID1/3-dependent invasive reprogramming in cancer cells.
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- Science Signaling, 2019, v. 12, n. 595, p. 1, doi. 10.1126/scisignal.aav2041
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- Article
A gene trap vector system for identifying transcriptionally responsive genes.
- Published in:
- Nature Biotechnology, 2001, v. 19, n. 6, p. 579, doi. 10.1038/89343
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- Publication type:
- Article
Erratum: Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
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- Nature Medicine, 2015, v. 21, n. 7, p. 827, doi. 10.1038/nm0715-827b
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- Publication type:
- Article
Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
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- Nature Medicine, 2015, v. 21, n. 7, p. 795, doi. 10.1038/nm.3870
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- Article
Stromal contribution to the colorectal cancer transcriptome.
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- Nature Genetics, 2015, v. 47, n. 4, p. 312, doi. 10.1038/ng.3224
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- Publication type:
- Article
A molecular signature for Epithelial to Mesenchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis.
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- Clinical & Experimental Metastasis, 2009, v. 26, n. 6, p. 569, doi. 10.1007/s10585-009-9256-9
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- Publication type:
- Article
Successful treatment with MEK‐inhibitor in a patient with NRAS‐related cutaneous skeletal hypophosphatemia syndrome.
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- Genes, Chromosomes & Cancer, 2022, v. 61, n. 12, p. 740, doi. 10.1002/gcc.23092
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- Publication type:
- Article
Detection of gene communities in multi-networks reveals cancer drivers.
- Published in:
- Scientific Reports, 2015, p. 17386, doi. 10.1038/srep17386
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- Publication type:
- Article
A diphtheria toxin resistance marker for in vitro and in vivo selection of stably transduced human cells.
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- Scientific Reports, 2015, p. 14721, doi. 10.1038/srep14721
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- Publication type:
- Article
Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity.
- Published in:
- Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01176-5
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- Publication type:
- Article
Formalin Fixation at Low Temperature Better Preserves Nucleic Acid Integrity.
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- PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021043
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- Publication type:
- Article
IGF-II Binding to Insulin Receptor Isoform A Induces a Partially Different Gene Expression Profile from Insulin Binding.
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- Annals of the New York Academy of Sciences, 2004, v. 1028, n. 1, p. 450, doi. 10.1196/annals.1322.053
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- Publication type:
- Article
Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells.
- Published in:
- Oncogene, 2004, v. 23, n. 12, p. 2188, doi. 10.1038/sj.onc.1207322
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- Publication type:
- Article
The RNA-Binding Protein ESRP1 Modulates the Expression of RAC1b in Colorectal Cancer Cells.
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- Cancers, 2021, v. 13, n. 16, p. 4092, doi. 10.3390/cancers13164092
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- Publication type:
- Article
Synthetic Lethality Screening Highlights Colorectal Cancer Vulnerability to Concomitant Blockade of NEDD8 and EGFR Pathways.
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- Cancers, 2021, v. 13, n. 15, p. 3805, doi. 10.3390/cancers13153805
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- Publication type:
- Article
Improved Outcome Prediction for Appendiceal Pseudomyxoma Peritonei by Integration of Cancer Cell and Stromal Transcriptional Profiles.
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- Cancers, 2020, v. 12, n. 6, p. 1495, doi. 10.3390/cancers12061495
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- Publication type:
- Article
IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas.
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- Cancers, 2018, v. 10, n. 1, p. 21, doi. 10.3390/cancers10010021
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- Publication type:
- Article
Semalytics: a semantic analytics platform for the exploration of distributed and heterogeneous cancer data in translational research.
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- Database: The Journal of Biological Databases & Curation, 2019, v. 2019, p. N.PAG, doi. 10.1093/database/baz080
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- Publication type:
- Article
Dual VEGFA/BRAF targeting boosts PD‐1 blockade in melanoma through GM‐CSF‐mediated infiltration of M1 macrophages.
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- Molecular Oncology, 2023, v. 17, n. 8, p. 1474, doi. 10.1002/1878-0261.13450
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- Publication type:
- Article
Exploiting orthologue diversity for systematic detection of gain-of-function phenotypes.
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- BMC Genomics, 2008, v. 9, p. 1, doi. 10.1186/1471-2164-9-254
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- Publication type:
- Article
Amplification of repeat‐containing transcribed sequences (ARTS): a transcriptome fingerprinting strategy to detect functionally relevant microsatellite mutations in cancer.
- Published in:
- Nucleic Acids Research, 2003, v. 31, n. 7, p. e33, doi. 10.1093/nar/gng033
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- Publication type:
- Article
Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer.
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- Nature Communications, 2017, v. 8, n. 5, p. 15107, doi. 10.1038/ncomms15107
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- Publication type:
- Article
MicroRNA-mRNA interactions underlying colorectal cancer molecular subtypes.
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- Nature Communications, 2015, v. 6, n. 11, p. 8878, doi. 10.1038/ncomms9878
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- Publication type:
- Article
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
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- Nature Communications, 2015, v. 6, n. 4, p. 7002, doi. 10.1038/ncomms8002
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- Publication type:
- Article
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell–like phenotype.
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- Science Translational Medicine, 2020, v. 12, n. 555, p. 1, doi. 10.1126/scitranslmed.aax8313
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- Publication type:
- Article
IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies.
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- Science Translational Medicine, 2015, v. 7, n. 272, p. 1, doi. 10.1126/scitranslmed.3010445
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- Publication type:
- Article
A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology.
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- 2019
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- Publication type:
- journal article
The MET oncogene drives a genetic programme linking cancer to haemostasis.
- Published in:
- Nature, 2005, v. 434, n. 7031, p. 396, doi. 10.1038/nature03357
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- Publication type:
- Article
Machine learning for RNA sequencing-based intrinsic subtyping of breast cancer.
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- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-70832-2
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- Article
Correction: Inhibition of the AURKA/YAP1 axis is a promising therapeutic option for overcoming cetuximab resistance in colorectal cancer stem cells.
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- 2024
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- Correction Notice
Inhibition of the AURKA/YAP1 axis is a promising therapeutic option for overcoming cetuximab resistance in colorectal cancer stem cells.
- Published in:
- British Journal of Cancer, 2024, v. 130, n. 8, p. 1402, doi. 10.1038/s41416-024-02649-z
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- Publication type:
- Article
Met overexpression confers HGF-dependent invasive phenotype to human thyroid carcinoma cells in vitro.
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- Journal of Cellular Physiology, 1999, v. 180, n. 3, p. 365, doi. 10.1002/(SICI)1097-4652(199909)180:3<365::AID-JCP7>3.0.CO;2-B
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- Publication type:
- Article
Transcriptional hallmarks of noonan syndrome and noonan-like syndrome with loose anagen hair.
- Published in:
- Human Mutation, 2012, v. 33, n. 4, p. 703, doi. 10.1002/humu.22026
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- Publication type:
- Article
Case report: Preclinical efficacy of NEDD8 and proteasome inhibitors in patient-derived models of signet ring high-grade mucinous colorectal cancer from a Lynch syndrome patient.
- Published in:
- Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1130852
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- Publication type:
- Article
MEK Inhibition in a Newborn with RAF1 -Associated Noonan Syndrome Ameliorates Hypertrophic Cardiomyopathy but Is Insufficient to Revert Pulmonary Vascular Disease.
- Published in:
- Genes, 2022, v. 13, n. 1, p. 6, doi. 10.3390/genes13010006
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- Publication type:
- Article
The neuronal protein Neuroligin 1 promotes colorectal cancer progression by modulating the APC/β-catenin pathway.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02465-4
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- Publication type:
- Article
Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models.
- Published in:
- BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-918
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- Publication type:
- Article
Search for Neuro-Endocrine Markers (Chromogranin A, Synaptophysin and VGF) in Breast Cancers. An integrated Approach Using Immunohistochemistry and Gene Expression Profiling.
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- Endocrine Pathology, 2014, v. 25, n. 3, p. 219, doi. 10.1007/s12022-013-9277-4
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- Publication type:
- Article
Gene expression profiling of HGF/Met activation in neonatal mouse heart.
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- Transgenic Research, 2013, v. 22, n. 3, p. 579, doi. 10.1007/s11248-012-9667-2
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- Publication type:
- Article
Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer.
- Published in:
- 2017
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- Publication type:
- journal article
Induction of MET by Ionizing Radiation and Its Role in Radioresistance and Invasive Growth of Cancer.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2011, v. 103, n. 8, p. 645, doi. 10.1093/jnci/djr093
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- Publication type:
- Article
Only a Subset of Met-Activated Pathways Are Required to Sustain Oncogene Addiction.
- Published in:
- Science Signaling, 2009, v. 2, n. 102, p. 1, doi. 10.1126/scisignal.2000643
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- Publication type:
- Article
Only a Subset of Met-Activated Pathways Are Required to Sustain Oncogene Addiction.
- Published in:
- Science Signaling, 2009, v. 2, n. 100, p. 1, doi. 10.1126/scisignal.2000643
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- Publication type:
- Article
Evolving neoantigen profiles in colorectal cancers with DNA repair defects.
- Published in:
- Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0654-6
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- Publication type:
- Article