Title: Impact of age on treatment utilization for newly diagnosed multiple myeloma: a nationwide retrospective cohort study.
Authors: Mohyuddin, Ghulam Rehman; Mian, Hira; Gayowsky, Anastasia; Seow, Hsien; Chakraborty, Rajshekhar; Pond, Gregory R.; Al Hadidi, Samer; Visram, Alissa
Abstract: The study published in the Blood Cancer Journal explores the impact of age and left-digit bias on treatment decisions for patients with multiple myeloma (MM). The research, conducted in Ontario, Canada, found a significant decline in the utilization of autologous stem cell transplant (ASCT) for patients aged between 65 and 75, with the most pronounced drop between ages 69-71. Despite adjusting for comorbidities and performance status, chronological age played a substantial role in treatment decisions for MM patients. The study suggests that decisions should be based on alternative measures of frailty and fitness rather than solely relying on chronological age.
Subjects: BISPECIFIC antibodies; AGE; BUSINESS partnerships; STEM cell transplantation; CHIMERIC antigen receptors
Publication: Blood Cancer Journal, 2024, Vol 14, Issue 1, p1
ISSN: 2044-5385
Publication type: Academic Journal
DOI: 10.1038/s41408-024-01164-x

Impact of age on treatment utilization for newly diagnosed multiple myeloma: a nationwide retrospective cohort study.

Mohyuddin, Ghulam Rehman; Mian, Hira; Gayowsky, Anastasia; Seow, Hsien; Chakraborty, Rajshekhar; Pond, Gregory R.; Al Hadidi, Samer; Visram, Alissa