Works matching IS 09509232 AND DT 2009 AND VI 28
Results: 428
YKL-40, a secreted glycoprotein, promotes tumor angiogenesis.
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- Oncogene, 2009, v. 28, n. 50, p. 4456, doi. 10.1038/onc.2009.292
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Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation.
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- Oncogene, 2009, v. 28, n. 50, p. 4469, doi. 10.1038/onc.2009.270
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RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1.
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- Oncogene, 2009, v. 28, n. 50, p. 4434, doi. 10.1038/onc.2009.303
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SNAI1 expression in colon cancer related with CDH1 and VDR downregulation in normal adjacent tissue.
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- Oncogene, 2009, v. 28, n. 49, p. 4375, doi. 10.1038/onc.2009.285
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Genetic inactivation of ApoJ/clusterin: effects on prostate tumourigenesis and metastatic spread.
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- Oncogene, 2009, v. 28, n. 49, p. 4344, doi. 10.1038/onc.2009.286
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The GAB2 signaling scaffold promotes anchorage independence and drives a transcriptional response associated with metastatic progression of breast cancer.
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- Oncogene, 2009, v. 28, n. 50, p. 4444, doi. 10.1038/onc.2009.296
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A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways.
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- Oncogene, 2009, v. 28, n. 50, p. 4421, doi. 10.1038/onc.2009.293
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The Sonic Hedgehog pathway stimulates prostate tumor growth by paracrine signaling and recapitulates embryonic gene expression in tumor myofibroblasts.
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- Oncogene, 2009, v. 28, n. 50, p. 4480, doi. 10.1038/onc.2009.294
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Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer.
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- Oncogene, 2009, v. 28, n. 50, p. 4491, doi. 10.1038/onc.2009.297
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Loss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer.
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- Oncogene, 2009, v. 28, n. 50, p. 4409, doi. 10.1038/onc.2009.295
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Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF<sup>Fbx4/αB-crystallin</sup> ligase and subsequent proteasome-dependent degradation.
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- Oncogene, 2009, v. 28, n. 49, p. 4317, doi. 10.1038/onc.2009.287
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Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage.
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- Oncogene, 2009, v. 28, n. 49, p. 4326, doi. 10.1038/onc.2009.299
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Heat shock protein 27 mediates repression of androgen receptor function by protein kinase D1 in prostate cancer cells.
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- Oncogene, 2009, v. 28, n. 49, p. 4386, doi. 10.1038/onc.2009.291
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Pannexin2 as a novel growth regulator in C6 glioma cells.
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- Oncogene, 2009, v. 28, n. 49, p. 4402, doi. 10.1038/onc.2009.283
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Telomerase deficiency and telomere dysfunction inhibit mammary tumors induced by polyomavirus middle T oncogene.
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- Oncogene, 2009, v. 28, n. 48, p. 4225, doi. 10.1038/onc.2009.268
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The DEAD-box protein p72 regulates ERα-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERα-positive breast cancer.
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- Oncogene, 2009, v. 28, n. 46, p. 4053, doi. 10.1038/onc.2009.261
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Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells.
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- Oncogene, 2009, v. 28, n. 49, p. 4364, doi. 10.1038/onc.2009.288
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TLR4 signaling induced by lipopolysaccharide or paclitaxel regulates tumor survival and chemoresistance in ovarian cancer.
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- Oncogene, 2009, v. 28, n. 49, p. 4353, doi. 10.1038/onc.2009.289
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Transcription activity is required for p53-dependent tumor suppression.
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- Oncogene, 2009, v. 28, n. 49, p. 4397, doi. 10.1038/onc.2009.290
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GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance.
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- Oncogene, 2009, v. 28, n. 46, p. 4126, doi. 10.1038/onc.2009.262
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PU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL.
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- Oncogene, 2009, v. 28, n. 46, p. 4116, doi. 10.1038/onc.2009.263
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A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis.
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- Oncogene, 2009, v. 28, n. 48, p. 4237, doi. 10.1038/onc.2009.272
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Synergistic proapoptotic effects of the two tyrosine kinase inhibitors pazopanib and lapatinib on multiple carcinoma cell lines.
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- Oncogene, 2009, v. 28, n. 48, p. 4249, doi. 10.1038/onc.2009.277
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PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis.
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- Oncogene, 2009, v. 28, n. 48, p. 4261, doi. 10.1038/onc.2009.276
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Regulation of miRNA expression by Src and contact normalization: effects on nonanchored cell growth and migration.
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- Oncogene, 2009, v. 28, n. 48, p. 4272, doi. 10.1038/onc.2009.278
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Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type- and mutation-specific manner.
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- Oncogene, 2009, v. 28, n. 48, p. 4306, doi. 10.1038/onc.2009.280
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Hsp70 molecular chaperones are required to support p53 tumor suppressor activity under stress conditions.
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- Oncogene, 2009, v. 28, n. 48, p. 4284, doi. 10.1038/onc.2009.281
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Pro-proliferative FoxM1 is a target of p53-mediated repression.
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- Oncogene, 2009, v. 28, n. 48, p. 4295, doi. 10.1038/onc.2009.282
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LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer.
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- Oncogene, 2009, v. 28, n. 47, p. 4189, doi. 10.1038/onc.2009.266
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Thyroid hormone receptor mutants implicated in human hepatocellular carcinoma display an altered target gene repertoire.
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- Oncogene, 2009, v. 28, n. 47, p. 4162, doi. 10.1038/onc.2009.265
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Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation.
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- Oncogene, 2009, v. 28, n. 47, p. 4212, doi. 10.1038/onc.2009.267
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The Cdk inhibitor p57<sup>Kip2</sup> controls LIM-kinase 1 activity and regulates actin cytoskeleton dynamics.
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- Oncogene, 2009, v. 28, n. 47, p. 4175, doi. 10.1038/onc.2009.269
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‘Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma’.
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- Oncogene, 2009, v. 28, n. 47, p. 4147, doi. 10.1038/onc.2009.284
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A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer.
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- Oncogene, 2009, v. 28, n. 47, p. 4133, doi. 10.1038/onc.2009.271
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RNA aptamers interfering with nucleophosmin oligomerization induce apoptosis of cancer cells.
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- Oncogene, 2009, v. 28, n. 47, p. 4201, doi. 10.1038/onc.2009.275
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p210<sup>Bcr−Abl</sup> desensitizes Cdc42 GTPase signaling for SDF-1α-directed migration in chronic myeloid leukemia cells.
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- Oncogene, 2009, v. 28, n. 46, p. 4105, doi. 10.1038/onc.2009.260
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The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene.
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- Oncogene, 2009, v. 28, n. 46, p. 4041, doi. 10.1038/onc.2009.259
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The neuroblastoma tumour-suppressor TrkAI and its oncogenic alternative TrkAIII splice variant exhibit geldanamycin-sensitive interactions with Hsp90 in human neuroblastoma cells.
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- Oncogene, 2009, v. 28, n. 46, p. 4075, doi. 10.1038/onc.2009.256
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Suppression of lung adenocarcinoma through menin and polycomb gene-mediated repression of growth factor pleiotrophin.
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- Oncogene, 2009, v. 28, n. 46, p. 4095, doi. 10.1038/onc.2009.273
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Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells.
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- Oncogene, 2009, v. 28, n. 46, p. 4065, doi. 10.1038/onc.2009.274
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Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death.
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- Oncogene, 2009, v. 28, n. 45, p. 4009, doi. 10.1038/onc.2009.250
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Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway.
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- Oncogene, 2009, v. 28, n. 45, p. 3960, doi. 10.1038/onc.2009.251
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Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α.
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- Oncogene, 2009, v. 28, n. 45, p. 3949, doi. 10.1038/onc.2009.252
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Anticancer DNA intercalators cause p53-dependent mitochondrial DNA nucleoid re-modelling.
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- Oncogene, 2009, v. 28, n. 44, p. 3880, doi. 10.1038/onc.2009.242
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Hepatic tumor–stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge.
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- Oncogene, 2009, v. 28, n. 45, p. 4022, doi. 10.1038/onc.2009.253
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A restricted signature of miRNAs distinguishes APL blasts from normal promyelocytes.
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- Oncogene, 2009, v. 28, n. 45, p. 4034, doi. 10.1038/onc.2009.255
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Three Epstein–Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle checkpoints.
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- Oncogene, 2009, v. 28, n. 45, p. 3997, doi. 10.1038/onc.2009.258
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Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2).
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- Oncogene, 2009, v. 28, n. 45, p. 3983, doi. 10.1038/onc.2009.264
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Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines.
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- Oncogene, 2009, v. 28, n. 44, p. 3926, doi. 10.1038/onc.2009.241
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Leupaxin acts as a mediator in prostate carcinoma progression through deregulation of p120catenin expression.
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- Oncogene, 2009, v. 28, n. 45, p. 3971, doi. 10.1038/onc.2009.254
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