Works matching DE "PROTEASE inhibitors"

Results: 4777

Overview and Management of Cardiac and Pulmonary Adverse Events in Patients With Relapsed and/or Refractory Multiple Myeloma Treated With Single-Agent Carfilzomib: Page 2 of 2.

Published in:

Oncology (08909091), 2013, v. 27, p. 1

By:

Wang, Michael;
Jie Cheng

Publication type:

Article

Overview and Management of Cardiac and Pulmonary Adverse Events in Patients With Relapsed and/or Refractory Multiple Myeloma Treated With Single-Agent Carfilzomib.

Published in:

Oncology (08909091), 2013, v. 27, p. 1

By:

Wang, Michael;
Jie Cheng

Publication type:

Article

Managing Adverse Events of Multiple Myeloma and Anti--Multiple Myeloma Treatment: A Perspective on Carfilzomib.

Published in:

Oncology (08909091), 2013, v. 27, p. 1

By:

Siegel, David S.

Publication type:

Article

Incidence and Management of Renal Adverse Events in Patients With Relapsed and/or Refractory Multiple Myeloma Treated With Single-Agent Carfilzomib.

Published in:

Oncology (08909091), 2013, v. 27, p. 1

By:

Shah, Jatin J.

Publication type:

Article

Incidence and Management of Renal Adverse Events in Patients With Relapsed and/or Refractory Multiple Myeloma Treated With Single-Agent Carfilzomib: Page 2 of 2.

Published in:

Oncology (08909091), 2013, v. 27, p. 1

By:

Shah, Jatin J.

Publication type:

Article

Novel Combination Therapies for Multiple Myeloma.

Published in:: Oncology (08909091), 2008, p. 25
Publication type:: Article

Ubiquitin sets the timer: impacts on aging and longevity.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 290, doi. 10.1038/nsmb.2806

By:

Kevei, Éva;
Hoppe, Thorsten

Publication type:

Article

New approaches for dissecting protease functions to improve probe development and drug discovery.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 1, p. 9, doi. 10.1038/nsmb.2203

By:

Deu, Edgar;
Verdoes, Martijn;
Bogyo, Matthew

Publication type:

Article

Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposure.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 6, p. 728, doi. 10.1038/nsmb.2055

By:

Kley, Juliane;
Schmidt, Bastian;
Boyanov, Boril;
Stolt-Bergner, Peggy C.;
Kirk, Rebecca;
Ehrmann, Michael;
Knopf, Ronit R.;
Naveh, Leah;
Adam, Zach;
Clausen, Tim

Publication type:

Article

Dynamic local unfolding in the serpin α-1 antitrypsin provides a mechanism for loop insertion and polymerization.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 2, p. 222, doi. 10.1038/nsmb.1976

By:

Krishnan, Beena;
Gierasch, Lila M.

Publication type:

Article

An APP inhibitory domain containing the Flemish mutation residue modulates γ-secretase activity for Aβ production.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 2, p. 151, doi. 10.1038/nsmb.1743

By:

Yuan Tian;
Bassit, Bhramdeo;
Deming Chau;
Yue-Ming Li

Publication type:

Article

SUMO protease SENP1 induces isomerization of the scissile peptide bond.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 12, p. 1069, doi. 10.1038/nsmb1172

By:

Shen, Linnan;
Tatham, Michael H.;
Changjiang Dong;
Zagórska, Anna;
Naismith, James H.;
Hay, Ronald T.

Publication type:

Article

Proteasome-mediated protein processing by bidirectional degradation initiated from an internal site.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 8, p. 691, doi. 10.1038/nsmb1122

By:

Piwko, Wojciech;
Jentsch, Stefan

Publication type:

Article

Induced structure of a helical switch as a mechanism to regulate enzymatic activity.

Published in:

Nature Structural & Molecular Biology, 2005, v. 12, n. 11, p. 1019, doi. 10.1038/nsmb1006

By:

Nomura, Anson M.;
Marnett, Alan B.;
Shimba, Nobuhisa;
Dötsch, Volker;
Craik, Charles S.

Publication type:

Article

Blocking HIV-1 virus assembly.

Published in:

Nature Structural & Molecular Biology, 2005, v. 12, n. 8, p. 638, doi. 10.1038/nsmb0805-638

By:

Vogt, Volker M.

Publication type:

Article

Risk Factors in Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome Patients Undergoing Antiretroviral Therapy in the State of Pernambuco, Brazil: A Case–Control Study.

Published in:

Metabolic Syndrome & Related Disorders, 2010, v. 8, n. 3, p. 271, doi. 10.1089/met.2009.0065

By:

Thais Gelenske;
Francisco Alfredo Bandeira e Farias;
Ricardo Arraes de Alencar Ximenes;
Heloísa Ramos Lacerda de Melo;
Maria de Fátima Pessoa Militão de Albuquerque;
Érico Higino de Carvalho;
Zoraya de Medeiros Barros;
George Tadeu Nunes Diniz;
Demócrito de Barros Miranda Filho

Publication type:

Article

Interaction between lopinavir/ritonavir and warfarin.

Published in:

2007

By:

Hughes, Christine A.;
Freitas, Andrea;
Miedzinski, Lilly J.

Publication type:

Case Study

Telaprevir: Changing the standard of care of chronic hepatitis C.

Published in:

Journal of Postgraduate Medicine, 2013, v. 59, n. 1, p. 42, doi. 10.4103/0022-3859.109493

By:

Rajani, A. K.;
Ravindra, B. K.;
Dkhar, S. A.

Publication type:

Article

Synthesis and Activity of Tyropeptin A Derivatives as Potent and Selective Inhibitors of Mammalian 20S Proteasome.

Published in:

Bioscience, Biotechnology & Biochemistry, 2005, v. 69, n. 9, p. 1733, doi. 10.1271/bbb.69.1733

By:

Momose, Isao;
Umezawa, Yoji;
Hirosawa, Sehei;
Iijima, Masatomi;
Iinuma, Hironobu;
Ikeda, Daishiro

Publication type:

Article

Contribution of Conserved Asn Residues to the Inhibitory Activities of Kunitz-Type Protease Inhibitors from Plants.

Published in:

Bioscience, Biotechnology & Biochemistry, 2005, v. 69, n. 1, p. 220, doi. 10.1271/bbb.69.220

By:

Iwanaga, Shiroh;
Yamasaki, Nobuyuki;
Kimura, Makoto;
Kouzuma, Yoshiaki

Publication type:

Article

Proteolytic Activity of Aspergillus flavus on Wool.

Published in:

AATCC Review, 2002, v. 2, n. 5, p. 30

By:

Cardamone, J. M.

Publication type:

Article

Expression of neprilysin, somatostatin and the somatostatin sst5 receptor in the hippocampal formation of brains from Alzheimer's disease patients.

Published in:

Psychogeriatrics, 2009, v. 9, n. 3, p. 132, doi. 10.1111/j.1479-8301.2009.00285.x

By:

Sekiguchi, Hirotaka;
Habuchi, Chikako;
Iritani, Shuji;
Arai, Tetsuaki;
Ozaki, Norio

Publication type:

Article

Aβ induces endoplasmic reticulum stress causing possible proteasome impairment via the endoplasmic reticulum–associated degradation pathway.

Published in:

Psychogeriatrics, 2006, v. 6, n. 3, p. 100, doi. 10.1111/j.1479-8301.2006.00141.x

By:

Kanayama, Daisuke;
Kudo, Takashi;
Kimura, Ryo;
Tabuchi, Nobuhiko;
Fukumori, Akio;
Morihara, Takeshi;
Tagami, Shinji;
Tanii, Hisashi;
Okochi, Masayasu;
Kamino, Kojin;
Tanaka, Toshihisa;
Imaizumi, Kazunori;
Tabira, Takeshi;
Takeda, Masatoshi

Publication type:

Article

Gender Differences in HIV Drug Resistance Mutations and Virological Outcome.

Published in:

Journal of Women's Health (15409996), 2011, v. 20, n. 1, p. 117, doi. 10.1089/jwh.2009.1846

By:

Mave, Vidya;
Gahunia, Mona;
Frontini, Maria;
Clark, Rebecca;
Mushatt, David

Publication type:

Article

Changes in the Vaginal Microenvironment with Metronidazole Treatment for Bacterial Vaginosis in Early Pregnancy.

Published in:

Journal of Women's Health (15409996), 2009, v. 18, n. 11, p. 1817, doi. 10.1089/jwh.2009.1378

By:

Mitchell, Caroline;
Balkus, Jennifer;
Agnew, Kathy;
Lawler, Richard;
Hitti, Jane

Publication type:

Article

Protein‐Templated Ugi Reactions versus In‐Situ Ligation Screening: Two Roads to the Identification of SARS‐CoV‐2 Main Protease Inhibitors.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 17, p. 1, doi. 10.1002/chem.202303940

By:

Wamser, Rebekka;
Zhang, Xinting;
Kuropka, Benno;
Arkona, Christoph;
Rademann, Jörg

Publication type:

Article

Rapid Chemical Synthesis of Serine Protease Inhibitor Kazal‐type 13 (SPINK13) Glycoform by a Combined Method with Glycan Insertion Strategy and Fast‐Flow Fmoc SPPS**.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 42, p. 1, doi. 10.1002/chem.202300646

By:

Nomura, Kota;
Okamoto, Ryo;
Maki, Yuta;
Hayashibara, Ayumu;
Takao, Toshifumi;
Fukuoka, Tomoya;
Miyoshi, Eiji;
Pentelute, Bradley L.;
Kajihara, Yasuhiro

Publication type:

Article

Ligand-based and structure-based studies to develop predictive models for SARS-CoV-2 main protease inhibitors through the 3d-qsar.com portal.

Published in:

Journal of Computer-Aided Molecular Design, 2022, v. 36, n. 7, p. 483, doi. 10.1007/s10822-022-00460-7

By:

Proia, Eleonora;
Ragno, Alessio;
Antonini, Lorenzo;
Sabatino, Manuela;
Mladenovič, Milan;
Capobianco, Roberto;
Ragno, Rino

Publication type:

Article

Conformational flexibility of DENV NS2B/NS3pro: from the inhibitor effect to the serotype influence.

Published in:

Journal of Computer-Aided Molecular Design, 2016, v. 30, n. 3, p. 251, doi. 10.1007/s10822-016-9901-8

By:

Piccirillo, Erika;
Merget, Benjamin;
Sotriffer, Christoph;
Amaral, Antonia

Publication type:

Article

Novel anti-Plasmodial hits identified by virtual screening of the ZINC database.

Published in:

Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 10, p. 859, doi. 10.1007/s10822-013-9685-z

By:

Mugumbate, Grace;
Newton, Ana S.;
Rosenthal, Philip J.;
Gut, Jiri;
Moreira, Rui;
Chibale, Kelly;
Guedes, Rita C.

Publication type:

Article

Binding of novel fullerene inhibitors to HIV-1 protease: insight through molecular dynamics and molecular mechanics Poisson-Boltzmann surface area calculations.

Published in:

Journal of Computer-Aided Molecular Design, 2011, v. 25, n. 10, p. 959, doi. 10.1007/s10822-011-9475-4

By:

Tzoupis, Haralambos;
Leonis, Georgios;
Durdagi, Serdar;
Mouchlis, Varnavas;
Mavromoustakos, Thomas;
Papadopoulos, Manthos

Publication type:

Article

Transferable scoring function based on semiempirical quantum mechanical PM6-DH2 method: CDK2 with 15 structurally diverse inhibitors.

Published in:

Journal of Computer-Aided Molecular Design, 2011, v. 25, n. 3, p. 223, doi. 10.1007/s10822-011-9413-5

By:

Dobeš, Petr;
Fanfrlík, Jindřich;
Řezáč, Jan;
Otyepka, Michal;
Hobza, Pavel

Publication type:

Article

Local neighborhood behavior in a combinatorial library context.

Published in:

Journal of Computer-Aided Molecular Design, 2011, v. 25, n. 3, p. 237, doi. 10.1007/s10822-011-9416-2

By:

Horvath, Dragos;
Koch, Christian;
Schneider, Gisbert;
Marcou, Gilles;
Varnek, Alexandre

Publication type:

Article

Structure-guided fragment-based in silico drug design of dengue protease inhibitors.

Published in:

Journal of Computer-Aided Molecular Design, 2011, v. 25, n. 3, p. 263, doi. 10.1007/s10822-011-9418-0

By:

Knehans, Tim;
Schüller, Andreas;
Doan, Danny N.;
Nacro, Kassoum;
Hill, Jeffrey;
Güntert, Peter;
Madhusudhan, M. S.;
Weil, Tanja;
Vasudevan, Subhash G.

Publication type:

Article

Possible allosteric interactions of monoindazole-substituted P2 cyclic urea analogues with wild-type and mutant HIV-1 protease.

Published in:

Journal of Computer-Aided Molecular Design, 2008, v. 22, n. 10, p. 737, doi. 10.1007/s10822-008-9210-y

By:

Garg, Rajni;
Bhhatarai, Barun

Publication type:

Article

Discovery of small molecule inhibitors of ubiquitin-like poxvirus proteinase I7L using homology modeling and covalent docking approaches.

Published in:

Journal of Computer-Aided Molecular Design, 2007, v. 21, n. 10/11, p. 549, doi. 10.1007/s10822-007-9138-7

By:

Katritch, Vsevolod;
Byrd, Chelsea M.;
Tseitin, Vladimir;
Dongcheng Dai;
Raush, Eugene;
Totrov, Maxim;
Abagyan, Ruben;
Jordan, Robert;
Hruby, Dennis

Publication type:

Article

Homology modeling and molecular interaction field studies of α-glucosidases as a guide to structure-based design of novel proposed anti-HIV inhibitors.

Published in:

Journal of Computer-Aided Molecular Design, 2005, v. 19, n. 2, p. 83, doi. 10.1007/s10822-005-1486-6

By:

C.H. Tomich;
da Silva, P.;
Carvalho, Ivone;
Taft, C. A.

Publication type:

Article

Model of full-length HIV-1 integrase complexed with viral DNA as template for anti-HIV drug design.

Published in:

Journal of Computer-Aided Molecular Design, 2004, v. 18, n. 12, p. 739, doi. 10.1007/s10822-005-0365-5

By:

Karki, Rajeshri G.;
Yun Tang;
Burke Jr., Terrence R.;
Nicklaus, Marc C.

Publication type:

Article

Enhancing the accuracy of virtual screening: molecular dynamics with quantum-refined force fields.

Published in:

Journal of Computer-Aided Molecular Design, 2004, v. 18, n. 12, p. 773, doi. 10.1007/s10822-004-7881-6

By:

Curioni, Alessandro;
Mordasini, Tiziana;
Andreoni, Wanda

Publication type:

Article

Protein-ligand binding free energy estimation using molecular mechanics and continuum electrostatics. Application to HIV-1 protease inhibitors.

Published in:

Journal of Computer-Aided Molecular Design, 2003, v. 17, n. 12, p. 861, doi. 10.1023/B:JCAM.0000021882.99270.4c

By:

Zoete, V.;
Michielin, O.;
Karplus, M.

Publication type:

Article

Inhibition and substrate recognition – a computational approach applied to HIV protease.

Published in:

Journal of Computer-Aided Molecular Design, 2003, v. 17, n. 9, p. 567, doi. 10.1023/B:JCAM.0000005748.19093.e8

By:

Vinkers, H. M.;
de Jonge, M. R.;
Daeyaert, F. D.;
Heeres, J.;
Koymans, L. M. H.;
van Lenthe, J. H.;
Lewi, P. J.;
Timmerman, H.;
Janssen, P. A. J.

Publication type:

Article

Classification of HIV protease inhibitors on the basis of their antiviral potency using radial basis function neural networks.

Published in:

Journal of Computer-Aided Molecular Design, 2003, v. 17, n. 2-4, p. 155, doi. 10.1023/A:1025317806473

By:

Patankar, S.J.;
Jurs, P.C.

Publication type:

Article

Proteasome inhibitor, bortezomib, for myeloma and lymphoma.

Published in:

International Journal of Clinical Oncology, 2007, v. 12, n. 5, p. 318, doi. 10.1007/s10147-007-0695-5

By:

Tobinai, Kensei

Publication type:

Article

Evolutionary Aspects of the Structural Convergence and Functional Diversification of Kunitz-Domain Inhibitors.

Published in:

Journal of Molecular Evolution, 2020, v. 88, n. 7, p. 537, doi. 10.1007/s00239-020-09959-9

By:

Mishra, Manasi

Publication type:

Article

Expression Patterns of Murine Antichymotrypsin-like Genes Reflect Evolutionary Divergence at theSerpina3Locus.

Published in:

Journal of Molecular Evolution, 2004, v. 59, n. 4, p. 488, doi. 10.1007/s00239-004-2640-9

By:

Horvath, Anita;
Forsyth, Sharon;
Coughlin, Paul

Publication type:

Article

The Molecular Evolutionary History of a Winged Bean α-Chymotrypsin Inhibitor and Modeling of Its Mutations Through Structural Analyses.

Published in:

Journal of Molecular Evolution, 2000, v. 50, n. 3, p. 214, doi. 10.1007/s002399910024

By:

Mukhopadhyay, Debashis

Publication type:

Article

Genetic diversity of the alpha‐1‐antitrypsin gene in Africans identified using a novel genotyping assayCommunicated by Michael Dean.

Published in:

Human Mutation, 2003, v. 22, n. 1, p. 59, doi. 10.1002/humu.10231

By:

Vanessa M. Hayes

Publication type:

Article

High incidence of delayed graft function in HIV-infected kidney transplant recipients.

Published in:

Transplant International, 2013, v. 26, n. 9, p. 893, doi. 10.1111/tri.12147

By:

Mazuecos, Auxiliadora;
Fernandez, Ana;
Zarraga, Sofia;
Andres, Amado;
Rodriguez-Benot, Alberto;
Jimenez, Carlos;
Gomez, Ernesto;
Paul, Javier;
Jimeno, Luisa;
Fernandez, Constatino;
Burgos, Dolores;
Sanchez-Fructuoso, Ana;
Guirado, Lluis

Publication type:

Article

Effect of intraportal infusion to improve small for size graft injury in living donor adult liver transplantation.

Published in:

Transplant International, 2005, v. 18, n. 8, p. 923, doi. 10.1111/j.1432-2277.2005.00159.x

By:

Suehiro, Taketoshi;
Shimada, Mitsuo;
Kishikawa, Keiji;
Shimura, Tatsuo;
Soejima, Yuji;
Yoshizumi, Tomoharu;
Hashimoto, Kohji;
Mochida, Yasushi;
Hashimoto, Shinji;
Maehara, Yoshihiko;
Kuwano, Hiroyuki

Publication type:

Article

Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases.

Published in:

Pflügers Archiv: European Journal of Physiology, 2010, v. 460, n. 1, p. 1, doi. 10.1007/s00424-010-0827-z

By:

Gaillard, Erol A.;
Kota, Pradeep;
Gentzsch, Martina;
Dokholyan, Nikolay V.;
Stutts, M. Jackson;
Tarran, Robert

Publication type:

Article