Works matching DE "ALLOSTERIC proteins"

Results: 368

Energetic analysis of the rhodopsin-G-protein complex links the α5 helix to GDP release.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 1, p. 56, doi. 10.1038/nsmb.2705

By:

Alexander, Nathan S;
Preininger, Anita M;
Kaya, Ali I;
Stein, Richard A;
Hamm, Heidi E;
Meiler, Jens

Publication type:

Article

Allosteric control of the ribosome by small-molecule antibiotics.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 957, doi. 10.1038/nsmb.2360

By:

Wang, Leyi;
Pulk, Arto;
Wasserman, Michael R;
Feldman, Michael B;
Altman, Roger B;
Doudna Cate, Jamie H;
Blanchard, Scott C

Publication type:

Article

Enhanced interrogation: emerging strategies for cell signaling inhibition.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 6, p. 646, doi. 10.1038/nsmb0610-646

By:

Huang, Rong;
Martinez-Ferrando, Isabel;
Cole, Philip A.

Publication type:

Article

Membrane-dependent signal integration by the Ras activator Son of sevenless.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 5, p. 452, doi. 10.1038/nsmb.1418

By:

Gureasko, Jodi;
Galush, William J.;
Boykevisch, Sean;
Sondermann, Holger;
Bar-Sagi, Dafna;
Groves, Jay T.;
Kuriyan, John

Publication type:

Article

Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 5, p. 432, doi. 10.1038/nsmb1236

By:

Reissmann, Stefanie;
Parnot, Charles;
Booth, Christopher R;
Wah Chiu;
Frydman, Judith

Publication type:

Article

Conformational restriction blocks glutamate receptor desensitization.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 12, p. 1120, doi. 10.1038/nsmb1178

By:

Weston, Matthew C.;
Schuck, Peter;
Ghosal, Alokesh;
Rosenmund, Christian;
Mayer, Mark L.

Publication type:

Article

Structural dynamics of native and V260E mutant C-terminal domain of HIV-1 integrase.

Published in:

Journal of Computer-Aided Molecular Design, 2015, v. 29, n. 4, p. 371, doi. 10.1007/s10822-015-9830-y

By:

Sangeetha, Balasubramanian;
Muthukumaran, Rajagopalan;
Amutha, Ramaswamy

Publication type:

Article

T-Analyst: a program for efficient analysis of protein conformational changes by torsion angles.

Published in:

Journal of Computer-Aided Molecular Design, 2010, v. 24, n. 10, p. 819, doi. 10.1007/s10822-010-9376-y

By:

Ai, Rizi;
Qaiser Fatmi, M.;
Chang, Chia-en

Publication type:

Article

Warfarin: history, tautomerism and activity.

Published in:

Journal of Computer-Aided Molecular Design, 2010, v. 24, n. 6/7, p. 553, doi. 10.1007/s10822-010-9335-7

By:

Porter, William R.

Publication type:

Article

Structural models in the assessment of protein druggability based on HTS data.

Published in:

Journal of Computer-Aided Molecular Design, 2009, v. 23, n. 8, p. 583, doi. 10.1007/s10822-009-9279-y

By:

Gupta, Anvita;
Gupta, Arun Kumar;
Seshadri, Kothandaraman

Publication type:

Article

A ligand’s-eye view of protein binding.

Published in:

Journal of Computer-Aided Molecular Design, 2008, v. 22, n. 6/7, p. 507, doi. 10.1007/s10822-008-9177-8

By:

Clark, Robert D.

Publication type:

Article

Inactive and active states and supramolecular organization of GPCRs: insights from computational modeling.

Published in:

Journal of Computer-Aided Molecular Design, 2006, v. 20, n. 7/8, p. 449, doi. 10.1007/s10822-006-9064-0

By:

Fanelli, Francesca;
De Benedetti, Pier G.

Publication type:

Article

Protein Alpha Shape (PAS) Dock: A new gaussian-based score function suitable for docking in homology modelled protein structures.

Published in:

Journal of Computer-Aided Molecular Design, 2006, v. 20, n. 3, p. 131, doi. 10.1007/s10822-006-9041-7

By:

Tøndel, Kristin;
Anderssen, Endre;
Drabløs, Finn

Publication type:

Article

A novel scoring function for molecular docking.

Published in:

Journal of Computer-Aided Molecular Design, 2003, v. 17, n. 9, p. 597, doi. 10.1023/B:JCAM.0000005766.95985.7e

By:

Muryshev, A. E.;
Tarasov, D. N.;
Butygin, A. V.;
Butygina, O. Yu.;
Aleksandrov, A. B.;
Nikitin, S. M.

Publication type:

Article

Preface.

Published in:

2019

By:

Gillies, Robert J.

Publication type:

Editorial

Universal allosteric mechanism for Gα activation by GPCRs.

Published in:

Nature, 2015, v. 524, n. 7564, p. 173, doi. 10.1038/nature14663

By:

Flock, Tilman;
Ravarani, Charles N. J.;
Sun, Dawei;
Venkatakrishnan, A. J.;
Kayikci, Melis;
Tate, Christopher G.;
Veprintsev, Dmitry B.;
Babu, M. Madan

Publication type:

Article

The ensemble nature of allostery.

Published in:

Nature, 2014, v. 508, n. 7496, p. 331, doi. 10.1038/nature13001

By:

Motlagh, Hesam N.;
Wrabl, James O.;
Li, Jing;
Hilser, Vincent J.

Publication type:

Article

Protein large-scale motions revealed by quantum beams: A new era in understanding protein dynamics.

Published in:

Biophysics & Physicobiology, 2022, v. 19, p. 1, doi. 10.2142/biophysico.bppb-v19.0035

By:

Naoki Yamamoto;
Rintaro Inoue;
Ikuo Kurisaki;
Tatsuhito Matsuo;
Yuki Hishikawa;
Wenyang Zhao;
Hiroshi Sekiguchi

Publication type:

Article

Structures of oxygen dissociation intermediates of 400 kDa V2 hemoglobin provide coarse snapshots of the protein allostery.

Published in:

Biophysics & Physicobiology, 2022, v. 19, p. 1, doi. 10.2142/biophysico.bppb-v19.0019

By:

Nobutaka Numoto;
Seiko Onoda;
Yoshiaki Kawano;
Hideo Okumura;
Seiki Baba;
Yoshihiro Fukumori;
Kunio Miki;
Nobutoshi Ito

Publication type:

Article

Oligonucleotide-based systems for input-controlled and non-covalently regulated protein binding.

Published in:

Supramolecular Chemistry, 2013, v. 25, n. 12, p. 848, doi. 10.1080/10610278.2013.810337

By:

Battle, Cooper;
Chu, Xiaozhu;
Jayawickramarajah, Janarthanan

Publication type:

Article

Protein recognition via oligonucleotide-linked small molecules: Utilisation of the hemin-binding aptamer.

Published in:

Supramolecular Chemistry, 2009, v. 21, n. 3/4, p. 316, doi. 10.1080/10610270802549717

By:

Harris, D. Calvin;
Chu, Xiaozhu;
Jayawickramarajah, Janarthanan

Publication type:

Article

A New Look at the Structures of Old Sepsis Actors by Exploratory Data Analysis Tools.

Published in:

Antibiotics (2079-6382), 2019, v. 8, n. 4, p. 225, doi. 10.3390/antibiotics8040225

By:

Gnoni, Antonio;
De Nitto, Emanuele;
Scacco, Salvatore;
Santacroce, Luigi;
Palese, Luigi Leonardo

Publication type:

Article

Improved Synthesis of First Cell-Permeable Allosteric PTPRZ Inhibitor NAZ2329.

Published in:

Russian Journal of General Chemistry, 2021, v. 91, n. 10, p. 2095, doi. 10.1134/S1070363221100273

By:

Hu, Wei;
Zeng, Qiang;
Chen, Weiming

Publication type:

Article

Understanding biomolecular motion, recognition, and allostery by use of conformational ensembles.

Published in:

European Biophysics Journal, 2011, v. 40, n. 12, p. 1339, doi. 10.1007/s00249-011-0754-8

By:

Fenwick, R.;
Esteban-Martín, Santi;
Salvatella, Xavier

Publication type:

Article

Adjustment of conformational flexibility of glyceraldehyde-3-phosphate dehydrogenase as a means of thermal adaptation and allosteric regulation.

Published in:

European Biophysics Journal, 2008, v. 37, n. 7, p. 1139, doi. 10.1007/s00249-008-0332-x

By:

Hajdú, István;
Bőthe, Csaba;
Szilágyi, András;
Kardos, József;
Gál, Péter;
Závodszky, Péter

Publication type:

Article

An alternative theoretical formula for hemoglobin oxygenation.

Published in:

European Biophysics Journal, 2008, v. 37, n. 6, p. 823, doi. 10.1007/s00249-008-0283-2

By:

Michel, Denis

Publication type:

Article

A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions.

Published in:

Biological Cybernetics, 1996, v. 75, n. 5, p. 361, doi. 10.1007/s004220050302

By:

Edelstein, Stuart J.;
Schaad, Olivier;
Henry, Eric;
Bertrand, Daniel;
Changeux, Jean-Pierre

Publication type:

Article

Addendum: Sensing the allosteric force.

Published in:

Nature Communications, 2023, v. 14, p. 1, doi. 10.1038/s41467-023-37893-z

By:

Jankovic, Brankica;
Bozovic, Olga;
Hamm, Peter

Publication type:

Article

Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37543-4

By:

Nguyen, Hong Thuy Vy;
Chen, Xiaorui;
Parada, Claudia;
Luo, An-Chi;
Shih, Orion;
Jeng, U-Ser;
Huang, Chia-Ying;
Shih, Yu-Ling;
Ma, Che

Publication type:

Article

Molecular Dynamic Simulation Reveals Structure Differences in APOL1 Variants and Implication in Pathogenesis of Chronic Kidney Disease.

Published in:

Genes, 2022, v. 13, n. 8, p. 1460, doi. 10.3390/genes13081460

By:

Mayanja, Richard;
Kintu, Christopher;
Diabate, Oudou;
Soremekun, Opeyemi;
Oluwagbemi, Olugbenga Oluseun;
Wele, Mamadou;
Kalyesubula, Robert;
Jjingo, Daudi;
Chikowore, Tinashe;
Fatumo, Segun

Publication type:

Article

Engineering allosteric regulation in protein kinases.

Published in:

Science Signaling, 2018, v. 11, n. 555, p. 1, doi. 10.1126/scisignal.aar3250

By:

Pincus, David;
Pandey, Jai P.;
Feder, Zoë A.;
Creixell, Pau;
Resnekov, Orna;
Reynolds, Kimberly A.

Publication type:

Article

"Disruptor" residues in the regulator of G protein signaling (RGS) R12 subfamily attenuate the inactivation of Gα subunits.

Published in:

Science Signaling, 2018, v. 11, n. 534, p. 1, doi. 10.1126/scisignal.aan3677

By:

Asli, Ali;
Sadiya, Isra;
Avital-Shacham, Meirav;
Kosloff, Mickey

Publication type:

Article

Modulation of neuronal microcircuit activities within the medial prefrontal cortex by mGluR5 positive allosteric modulator.

Published in:

Journal of Psychopharmacology, 2014, v. 28, n. 10, p. 935, doi. 10.1177/0269881114542856

By:

Pollard, Marie;
Bartolome, Jose Manuel;
Conn, P Jeffrey;
Steckler, Thomas;
Shaban, Hamdy

Publication type:

Article

The long and short of adaptor appendages.

Published in:

Nature Structural Biology, 2003, v. 10, n. 8, p. 580, doi. 10.1038/nsb0803-580

By:

Knuehl, Christine;
Brodsky, Frances M

Publication type:

Article

CooA, CAP and allostery.

Published in:

Nature Structural Biology, 2000, v. 7, n. 10, p. 822, doi. 10.1038/79559

By:

Chan, Michael K.

Publication type:

Article

Allosteric selection of ribozymes that respond to the second messengers cGMP and cAMP.

Published in:

Nature Structural Biology, 1999, v. 6, n. 11, p. 1062

By:

Koizumi, Makoto;
Soukup, Garrett A.;
Kerr, Jo Nita Q.;
Breaker, Ronald R.

Publication type:

Article

Is cooperative oxygen binding by hemoglobin really understood?

Published in:

Nature Structural Biology, 1999, v. 6, n. 4, p. 351, doi. 10.1038/7586

By:

Eaton, William A.;
Henry, Eric. R.;
Hofrichter, James;
Mozzarelli, Andrea

Publication type:

Article

Special Issue: "Molecular Dynamics Simulations and Structural Analysis of Protein Domains".

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 19, p. 10793, doi. 10.3390/ijms251910793

By:

de Brevern, Alexandre G.

Publication type:

Article

Predicting Mutation-Induced Allosteric Changes in Structures and Conformational Ensembles of the ABL Kinase Using AlphaFold2 Adaptations with Alanine Sequence Scanning.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 18, p. 10082, doi. 10.3390/ijms251810082

By:

Raisinghani, Nishank;
Alshahrani, Mohammed;
Gupta, Grace;
Verkhivker, Gennady

Publication type:

Article

Utilizing Molecular Dynamics Simulations, Machine Learning, Cryo-EM, and NMR Spectroscopy to Predict and Validate Protein Dynamics.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 17, p. 9725, doi. 10.3390/ijms25179725

By:

Son, Ahrum;
Kim, Woojin;
Park, Jongham;
Lee, Wonseok;
Lee, Yerim;
Choi, Seongyun;
Kim, Hyunsoo

Publication type:

Article

Exploring Binding Pockets in the Conformational States of the SARS-CoV-2 Spike Trimers for the Screening of Allosteric Inhibitors Using Molecular Simulations and Ensemble-Based Ligand Docking.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 9, p. 4955, doi. 10.3390/ijms25094955

By:

Gupta, Grace;
Verkhivker, Gennady

Publication type:

Article

An Update on Protein Kinases as Therapeutic Targets—Part II: Peptides as Allosteric Protein Kinase C Modulators Targeting Protein–Protein Interactions.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 24, p. 17504, doi. 10.3390/ijms242417504

By:

Zerihun, Mulate;
Rubin, Samuel J. S.;
Silnitsky, Shmuel;
Qvit, Nir

Publication type:

Article

The Complexity and Multiplicity of the Specific cAMP Phosphodiesterase Family: PDE4, Open New Adapted Therapeutic Approaches.

Published in:

2022

By:

Lugnier, Claire

Publication type:

Literature Review

Double Mutant Cycles as a Tool to Address Folding, Binding, and Allostery.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 2, p. 828, doi. 10.3390/ijms22020828

By:

Pagano, Livia;
Toto, Angelo;
Malagrinò, Francesca;
Visconti, Lorenzo;
Jemth, Per;
Gianni, Stefano

Publication type:

Article

The 14-3-3 Proteins as Important Allosteric Regulators of Protein Kinases.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8824, doi. 10.3390/ijms21228824

By:

Obsilova, Veronika;
Obsil, Tomas

Publication type:

Article

Search of Allosteric Inhibitors and Associated Proteins of an AKT-like Kinase from Trypanosoma cruzi.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3951, doi. 10.3390/ijms19123951

By:

Ochoa, Rodrigo;
Rocha-Roa, Cristian;
Marín-Villa, Marcel;
Robledo, Sara M.;
Varela-M, Rubén E.

Publication type:

Article

Designed Elastic Networks: Models of Complex Protein Machinery.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 10, p. 3152, doi. 10.3390/ijms19103152

By:

Flechsig, Holger;
Togashi, Yuichi

Publication type:

Article

NS3 Protease from Hepatitis C Virus: Biophysical Studies on an Intrinsically Disordered Protein Domain.

Published in:

International Journal of Molecular Sciences, 2013, v. 14, n. 7, p. 13281, doi. 10.3390/ijms140713282

By:

Vega, Sonia;
Neira, Jose L.;
Marcuello, Carlos;
Lostao, Anabel;
Abian, Olga;
Velazquez-Campoy, Adrian

Publication type:

Article

Exploiting protein flexibility to predict the location of allosteric sites.

Published in:

BMC Bioinformatics, 2012, v. 13, n. 1, p. 1, doi. 10.1186/1471-2105-13-273

By:

Panjkovich, Alejandro;
Daura, Xavier

Publication type:

Article

A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease.

Published in:

PLoS Pathogens, 2017, v. 13, n. 5, p. 1, doi. 10.1371/journal.ppat.1006411

By:

Brecher, Matthew;
Li, Zhong;
Liu, Binbin;
Zhang, Jing;
Koetzner, Cheri A.;
Alifarag, Adham;
Jones, Susan A.;
Lin, Qishan;
Kramer, Laura D.;
Li, Hongmin

Publication type:

Article