- Title
Glia: Schwann cells provide life support for axons.
- Authors
Whalley, Katherine
- Abstract
The article highlights a study that reveals the molecular pathways through which Schwann cells sustain peripheral nervous system (PNS) axon integrity. The researchers generated transgenic mice to examine the role of Schwann cells in axon support by glia. The mice exhibited progressive degeneration of myelinated and unmyelinated axons in the peripheral nerves.
- Subjects
SCHWANN cells; PERIPHERAL nervous system; LABORATORY mice; AXONS; DEGENERATION (Pathology)
- Publication
Nature Reviews Neuroscience, 2014, Vol 15, Issue 11, p698
- ISSN
1471-003X
- Publication type
Academic Journal
- DOI
10.1038/nrn3840