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Title

Antitoxins: novel strategies to target agents of bioterrorism.

Authors

Rainey, G. Jonah A.; Young, John A. T.

Abstract

Never before has there been such a strong possibility that biological agents might be used indiscriminately on civilian populations. This review focuses on the use of antitoxins — antibodies, receptor decoys, dominant-negative inhibitors of translocation, small-molecule inhibitors and substrate analogues — to counteract those biological weapons for which toxins are an important mechanism of disease pathogenesis.

Subjects

ANTITOXINS; IMMUNOGLOBULINS; TOXINS; BIOLOGICAL weapons; BIOSECURITY; PATHOLOGY

Publication

Nature Reviews Microbiology, 2004, Vol 2, Issue 9, p721

ISSN

1740-1526

Publication type

Academic Journal

DOI

10.1038/nrmicro977

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