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Title

Bacterial pathogenesis: A sweet interaction with death for EPEC.

Authors

Molloy, Sheilagh

Abstract

The article focuses on the two research papers which reveal that an effector protein NleB blocks death receptor signalling. It states that an NleB is an effector protein for enteropathogenic Escherichia coli (EPEC) which regulates a range of host cell processes. It notes that EPEC NleB can block death receptor signalling through the transferase activity of N-acetylglucosamine (GlcNAc).

Subjects

DEATH receptors; ESCHERICHIA coli proteins; HOST-bacteria relationships; TRANSFERASES; N-acetylglucosamine

Publication

Nature Reviews Microbiology, 2013, Vol 11, Issue 10, p659

ISSN

1740-1526

Publication type

Academic Journal

DOI

10.1038/nrmicro3127

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