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- Title
The ins and outs of hepatitis C virus entry and assembly.
- Authors
Lindenbach, Brett D.; Rice, Charles M.
- Abstract
Hepatitis C virus, a major human pathogen, produces infectious virus particles with several unique features, such as an ability to interact with serum lipoproteins, a dizzyingly complicated process of virus entry, and a pathway of virus assembly and release that is closely linked to lipoprotein secretion. Here, we review these unique features, with an emphasis on recent discoveries concerning virus particle structure, virus entry and virus particle assembly and release.
- Subjects
BLOOD lipoproteins; LIVER diseases; HEPATITIS C transmission; LIVER cancer; CANCER risk factors
- Publication
Nature Reviews Microbiology, 2013, Vol 11, Issue 10, p688
- ISSN
1740-1526
- Publication type
Academic Journal
- DOI
10.1038/nrmicro3098