Title: The ins and outs of hepatitis C virus entry and assembly.
Authors: Lindenbach, Brett D.; Rice, Charles M.
Abstract: Hepatitis C virus, a major human pathogen, produces infectious virus particles with several unique features, such as an ability to interact with serum lipoproteins, a dizzyingly complicated process of virus entry, and a pathway of virus assembly and release that is closely linked to lipoprotein secretion. Here, we review these unique features, with an emphasis on recent discoveries concerning virus particle structure, virus entry and virus particle assembly and release.
Subjects: BLOOD lipoproteins; LIVER diseases; HEPATITIS C transmission; LIVER cancer; CANCER risk factors
Publication: Nature Reviews Microbiology, 2013, Vol 11, Issue 10, p688
ISSN: 1740-1526
Publication type: Academic Journal
DOI: 10.1038/nrmicro3098

The ins and outs of hepatitis C virus entry and assembly.

Lindenbach, Brett D.; Rice, Charles M.