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Title

Sticking together: building a biofilm the Bacillus subtilis way.

Authors

Vlamakis, Hera; Chai, Yunrong; Beauregard, Pascale; Losick, Richard; Kolter, Roberto

Abstract

Biofilms are ubiquitous communities of tightly associated bacteria encased in an extracellular matrix. Bacillus subtilis has long served as a robust model organism to examine the molecular mechanisms of biofilm formation, and a number of studies have revealed that this process is regulated by several integrated pathways. In this Review, we focus on the molecular mechanisms that control B. subtilis biofilm assembly, and then briefly summarize the current state of knowledge regarding biofilm disassembly. We also discuss recent progress that has expanded our understanding of B. subtilis biofilm formation on plant roots, which are a natural habitat for this soil bacterium.

Subjects

BACILLUS subtilis; BIOFILMS; GRAM-positive bacteria; SOIL microbiology; PLANT roots

Publication

Nature Reviews Microbiology, 2013, Vol 11, Issue 3, p157

ISSN

1740-1526

Publication type

Academic Journal

DOI

10.1038/nrmicro2960

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