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- Title
Sticking together: building a biofilm the Bacillus subtilis way.
- Authors
Vlamakis, Hera; Chai, Yunrong; Beauregard, Pascale; Losick, Richard; Kolter, Roberto
- Abstract
Biofilms are ubiquitous communities of tightly associated bacteria encased in an extracellular matrix. Bacillus subtilis has long served as a robust model organism to examine the molecular mechanisms of biofilm formation, and a number of studies have revealed that this process is regulated by several integrated pathways. In this Review, we focus on the molecular mechanisms that control B. subtilis biofilm assembly, and then briefly summarize the current state of knowledge regarding biofilm disassembly. We also discuss recent progress that has expanded our understanding of B. subtilis biofilm formation on plant roots, which are a natural habitat for this soil bacterium.
- Subjects
BACILLUS subtilis; BIOFILMS; GRAM-positive bacteria; SOIL microbiology; PLANT roots
- Publication
Nature Reviews Microbiology, 2013, Vol 11, Issue 3, p157
- ISSN
1740-1526
- Publication type
Academic Journal
- DOI
10.1038/nrmicro2960