Results
Title

West Nile virus infection and immunity.

Authors

Suthar, Mehul S.; Diamond, Michael S.; Gale Jr, Michael

Abstract

West Nile virus (WNV) is an emerging neurotropic flavivirus that is transmitted to humans through the bite of an infected mosquito. WNV has disseminated broadly in the Western hemisphere and now poses a significant public health risk. The continuing spread of WNV, combined with the lack of specific therapeutics or vaccines to combat or prevent infection, imparts a pressing need to identify the viral and host processes that control the outcome of and immunity to WNV infection. Here, we provide an overview of recent research that has revealed the virus-host interface controlling WNV infection and immunity.

Subjects

WEST Nile virus; FLAVIVIRAL diseases; MOSQUITO vectors; INFECTION prevention; IMMUNITY; MEDICAL care; INSECTS

Publication

Nature Reviews Microbiology, 2013, Vol 11, Issue 2, p115

ISSN

1740-1526

Publication type

Academic Journal

DOI

10.1038/nrmicro2950