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Title

Immunology: Splice-tailored to fit the bug.

Authors

Papatriantafyllou, Maria

Abstract

The article discusses research being done on immunology. It references the study "Anopheles NF-KB-regulated splicing factors direct pathogen-specific repertoires of the hypervariable pattern recognition receptor AgDscam," by Y. Dong and colleagues in the 2012 issue of the journal "Cell Host Microbe." It mentions that the study shows that nuclear factor-KB-mediated transcription downstream of the Toll and Imd pathways can shape the Down's syndrome cell adhesion molecule (DSCAM) pathogen.

Subjects

IMMUNOLOGY; NF-kappa B; CELL adhesion molecules; DOWN syndrome; GENETIC transcription; PATHOGENIC microorganisms

Publication

Nature Reviews Microbiology, 2012, Vol 10, Issue 12, p804

ISSN

1740-1526

Publication type

Academic Journal

DOI

10.1038/nrmicro2922