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- Title
Immune evasion: Gm18, a bacterial 'invisibility cloak'.
- Authors
David, Rachel
- Abstract
The article discusses research being done on bacterial transfer ribonucleic acid (tRNA). It references the studies related to identification of modification in microbial, native tRNA by S. Gehrig and colleagues and the 2'-O-methylation status of single guanosine controls transfer RNA-mediated Toll-like receptor 7 activation or inhibition by S. Jöckel and colleagues. The studies revealed that Gm18 on native bacterial tRNA can suppress immune activation via Toll-like receptor 7 (TLR7).
- Subjects
TRANSFER RNA; METHYLATION; MONONUCLEOSIS; TOLL-like receptors; JOCKEL, S.; GEHRIG, S.
- Publication
Nature Reviews Microbiology, 2012, Vol 10, Issue 4, p238
- ISSN
1740-1526
- Publication type
Academic Journal
- DOI
10.1038/nrmicro2767