Results
Title

Immune evasion: Gm18, a bacterial 'invisibility cloak'.

Authors

David, Rachel

Abstract

The article discusses research being done on bacterial transfer ribonucleic acid (tRNA). It references the studies related to identification of modification in microbial, native tRNA by S. Gehrig and colleagues and the 2'-O-methylation status of single guanosine controls transfer RNA-mediated Toll-like receptor 7 activation or inhibition by S. Jöckel and colleagues. The studies revealed that Gm18 on native bacterial tRNA can suppress immune activation via Toll-like receptor 7 (TLR7).

Subjects

TRANSFER RNA; METHYLATION; MONONUCLEOSIS; TOLL-like receptors; JOCKEL, S.; GEHRIG, S.

Publication

Nature Reviews Microbiology, 2012, Vol 10, Issue 4, p238

ISSN

1740-1526

Publication type

Academic Journal

DOI

10.1038/nrmicro2767