Results
Title

Expressions of individuality.

Authors

Chappell, Lia

Abstract

The article presents a study by Y. Kang and colleagues which demonstrates the abilities of total transcript amplification (TTA), a form of single-cell transcriptomics, in overcoming technical difficulties in gene expression changes in bacterial culture. The study used laser capture microdissection and large-scale RNA extractions. Results show that relative abundance between transcript within transcriptome are not sustained by TTA, and the strength of TTA is the ability to compare single cells.

Subjects

GENE amplification; KANG, Y.; BACTERIAL cultures; MICRODISSECTION; LASER therapy

Publication

Nature Reviews Microbiology, 2011, Vol 9, Issue 10, p701

ISSN

1740-1526

Publication type

Academic Journal

DOI

10.1038/nrmicro2662