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- Title
Parasitology: Antigen switching joins the DOTs.
- Authors
Jermy, Andrew
- Abstract
The article provides information on a study conducted by L. M. Figueiredo, C. J. Janzen and G. A. Cross to identify the role of epigenetic regulation in the switching and immune evasion of antigen by the parasite called Trypanosoma brucei. An important first step in understanding the epigenetic regulation of antigenic variation in Trypanosoma spp. is the identification of DOT1B as a regulator of bloodstream expression site (BES) switching.
- Subjects
PARASITOLOGICAL research; TRYPANOSOMA brucei; ANTIGENS; FIGUEIREDO, L. M.; JANZEN, C. J.; CROSS, G. A.
- Publication
Nature Reviews Microbiology, 2008, Vol 6, Issue 9, p650
- ISSN
1740-1526
- Publication type
Academic Journal
- DOI
10.1038/nrmicro1975