Results
Title

HIV: Editing HIV entry.

Authors

Minton, Kirsty

Abstract

The article provides information on a study conducted by E. E. Perez and colleagues to determine the potential of a genome-editing approach targeting the CC-chemokine receptor CCR5 to reconstitute immune function in HIV individuals by creating CD4 . It mentions that the primary human CD4 T cells were transduced with CCR5-zinc-finger nucleases (ZFNs) to explore the clinical feasibility of the approach, and later propagated in culture.

Subjects

MICROBIOLOGY; CHEMOKINES; HIV; NUCLEASES; PEREZ, E. E.

Publication

Nature Reviews Microbiology, 2008, Vol 6, Issue 9, p651

ISSN

1740-1526

Publication type

Academic Journal

DOI

10.1038/nrmicro1970