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- Title
Symbiotic conversations are revealed under genetic interrogation.
- Authors
Ruby, Edward G.
- Abstract
The recent development and application of molecular genetics to the symbionts of invertebrate animal species have advanced our knowledge of the biochemical communication that occurs between the host and its bacterial symbionts. In particular, the ability to manipulate these associations experimentally by introducing genetic variants of the symbionts into naive hosts has allowed the discovery of novel colonization mechanisms and factors. In addition, the role of the symbionts in inducing normal host development has been revealed, and its molecular basis described. In this Review, I discuss many of these developments, focusing on what has been discovered in five well-understood model systems.
- Subjects
GENETICS; MOLECULAR genetics; INVERTEBRATES; HUMAN genetic variation; BIOCHEMICAL genetics
- Publication
Nature Reviews Microbiology, 2008, Vol 6, Issue 10, p752
- ISSN
1740-1526
- Publication type
Academic Journal
- DOI
10.1038/nrmicro1958