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- Title
Towards nanomicrobiology using atomic force microscopy.
- Authors
Dufrêne, Yves F.
- Abstract
At the cross-roads of nanoscience and microbiology, the nanoscale analysis of microbial cells using atomic force microscopy (AFM) is an exciting, rapidly evolving research field. Over the past decade, there has been tremendous progress in our use of AFM to observe membrane proteins and live cells at high resolution. Remarkable advances have also been made in applying force spectroscopy to manipulate single membrane proteins, to map surface properties and receptor sites on cells and to measure cellular interactions at the single-cell and single-molecule levels. In addition, recent developments in cantilever nanosensors have opened up new avenues for the label-free detection of microorganisms and bioanalytes.
- Subjects
NANOSCIENCE; MICROBIOLOGY; ATOMIC force microscopy; MEMBRANE proteins; DETECTION of microorganisms; SPECTRUM analysis
- Publication
Nature Reviews Microbiology, 2008, Vol 6, Issue 9, p674
- ISSN
1740-1526
- Publication type
Academic Journal
- DOI
10.1038/nrmicro1948