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Title

RNA: Extending the network of sRNA control.

Authors

Jones, Susan

Abstract

The article reports on the study which states that GcvB, a 200-nucleotide small non-coding RNAs (sRNA), directly regulates 7 mRNAs that encode periplasmic peptide and amino acid transport proteins in Salmonella enterica serovar Typhimurium. It states that GcvB sRNA represses translation of the dppA and oppA peptide transporter genes in nutrient-rich conditions. It adds that biochemical assays revealed that GcvB functions as a sequence-specific inhibitor of translation.

Subjects

NUCLEOTIDES; NON-coding RNA; MESSENGER RNA; AMINO acids; PROTEINS; SALMONELLA; PEPTIDES

Publication

Nature Reviews Microbiology, 2008, Vol 6, Issue 1, p4

ISSN

1740-1526

Publication type

Academic Journal

DOI

10.1038/nrmicro1826

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