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- Title
RNA: Extending the network of sRNA control.
- Authors
Jones, Susan
- Abstract
The article reports on the study which states that GcvB, a 200-nucleotide small non-coding RNAs (sRNA), directly regulates 7 mRNAs that encode periplasmic peptide and amino acid transport proteins in Salmonella enterica serovar Typhimurium. It states that GcvB sRNA represses translation of the dppA and oppA peptide transporter genes in nutrient-rich conditions. It adds that biochemical assays revealed that GcvB functions as a sequence-specific inhibitor of translation.
- Subjects
NUCLEOTIDES; NON-coding RNA; MESSENGER RNA; AMINO acids; PROTEINS; SALMONELLA; PEPTIDES
- Publication
Nature Reviews Microbiology, 2008, Vol 6, Issue 1, p4
- ISSN
1740-1526
- Publication type
Academic Journal
- DOI
10.1038/nrmicro1826