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Title

Malaria vaccines: the stage we are at.

Authors

Todryk, Stephen M.; Hill, Adrian V. S.

Abstract

With over 1 million deaths annually attributed to malaria, an effective vaccine is an urgently needed intervention. However, the various stages of the malaria parasite lifecycle have differing protective immune mechanisms and clinical endpoints, and usually different, often polymorphic, antigens. Trials using an increasing variety of vaccine platforms and antigens are under way in an attempt to achieve this long-awaited goal.

Subjects

MALARIA; PLASMODIUM; VACCINES; ANTIGENS; IMMUNITY

Publication

Nature Reviews Microbiology, 2007, Vol 5, Issue 7, p487

ISSN

1740-1526

Publication type

Academic Journal

DOI

10.1038/nrmicro1712

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