Title: HIV: Under pressure.
Authors: Bird, Lucy
Abstract: Presents the result of a study on the resistance developed by virus under pressure against cytotoxic T lymphocyte (CTL)-mediated antiviral activity due to genotypic changes. Factors that contribute to the pressure in which HIV mutations depend; Reasons behind the emergence of HIV escape mutations; Details of the CTL clones used in the study.
Subjects: VIRUSES; CELL-mediated cytotoxicity; LYMPHOCYTES; ANTIVIRAL agents; GENETIC mutation
Publication: Nature Reviews Immunology, 2003, Vol 3, Issue 7, p518
ISSN: 1474-1733
Publication type: Academic Journal
DOI: 10.1038/nri1136

HIV: Under pressure.

Bird, Lucy