Works matching DE "ANTIBODY-directed enzyme prodrug therapy"

Results: 96

Wohldefinierte polymere Paclitaxel-Prodrugs über eine Grafting-From-Methode ausgehend vom Arzneistoff.

Published in:

Angewandte Chemie, 2016, v. 128, n. 39, p. 11967, doi. 10.1002/ange.201605892

By:

Louage, Benoit;
Nuhn, Lutz;
Risseeuw, Martijn D. P.;
Vanparijs, Nane;
De Coen, Ruben;
Karalic, Izet;
Van Calenbergh, Serge;
De Geest, Bruno G.

Publication type:

Article

Two cases of paralitic ileus in onco-hematologic patients.

Published in:

Pediatric Reports, 2012, v. 4, n. 1, p. 10, doi. 10.4081/pr.2012.e3

By:

Carraro, Francesca;
Rivetti, Elisa;
Romano, Erica;
Fagioli, Franca

Publication type:

Article

Characterization of a fusion protein of RGD4Cand the β-lactamase variant for antibody-directed enzyme prodrug therapy.

Published in:

OncoTargets & Therapy, 2014, v. 7, p. 535, doi. 10.2147/OTT.S59346

By:

Xiaoliang Zhou;
Hao Wang;
Peiji Shi;
Ai-min Meng

Publication type:

Article

Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment.

Published in:

PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0196254

By:

Rashidi, Fatma B.;
AlQhatani, Alanod D.;
Bashraheel, Sara S.;
Shaabani, Shabnam;
Groves, Matthew R.;
Dömling, Alexander;
Goda, Sayed K.

Publication type:

Article

Production of Long-Acting CNGRC–CPG2 Fusion Proteins: New Derivatives to Overcome Drug Immunogenicity of Ligand-Directed Enzyme Prodrug Therapy for Targeted Cancer Treatment.

Published in:

Technology in Cancer Research & Treatment, 2021, p. 1, doi. 10.1177/15330338211057371

By:

Al-mansoori, Layla;
Al Qahtani, Alanod D.;
Elsinga, Philip;
Goda, Sayed K.

Publication type:

Article

Practical Synthesis of N‐Alkyl‐N‐alkyloxycarbonylaminomethyl Prodrug Derivatives of Acetaminophen, Theophylline, and 6‐Mercaptopurine.

Published in:

Synthetic Communications, 2006, v. 36, n. 23, p. 3537, doi. 10.1080/00397910600943501

By:

Majumdar, Susruta;
Sloan, KennethB.

Publication type:

Article

Immunomodulatory Role of Chloroquine and Pyrimethamine in Plasmodium yoelii 17XL Infected Mice.

Published in:

Scandinavian Journal of Immunology, 2007, v. 65, n. 1, p. 54, doi. 10.1111/j.1365-3083.2006.01869.x

By:

Ramos-Avila, A.;
Ventura-Gallegos, J. L.;
Zentella-Dehesa, A.;
Machuca-Rodríguez, C.;
Moreno-Altamirano, M. M.;
Narváez, V.;
Legorreta-Herrera, M.

Publication type:

Article

Adenoviral delivery of pan-caspase inhibitor p35enhances bystander killing by P450 gene-directedenzyme prodrug therapy usingcyclophosphamide+.

Published in:

BMC Cancer, 2010, v. 10, p. 487, doi. 10.1186/1471-2407-10-487

By:

Doloff, Joshua C.;
Ting Su;
Waxman, David J.

Publication type:

Article

Synthesis of 3'-Amino-3'-Deoxyguanosine and 3'-Amino-3'-Deoxyxyloguanosine Monophosphate Hepdirect Prodrugs from Guanosine.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2009, v. 28, n. 10, p. 969, doi. 10.1080/15257770903307151

By:

Bookser, BrettC.;
Raffaele, NicholasB.;
Reddy, K.Raja;
Fan, Kevin;
Huang, Wenjian;
Erion, MarkD.

Publication type:

Article

“Lock-in” Modified Cyclo Sal Nucleotides—The Second Generation of Cyclo Sal Prodrugs.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2005, v. 24, n. 5-7, p. 939, doi. 10.1081/NCN-200059298

By:

Vukadinović, D.;
Böge, N. P. H.;
Balzarini, J.;
Meier, C.

Publication type:

Article

Ciclesonide in the Management of Asthma.

Published in:

Clinical Medicine: Therapeutics, 2009, n. 1, p. 1437, doi. 10.4137/CMT.S2133

By:

Gonzalez, Daniel;
Derendorf, Hartmut

Publication type:

Article

Antibody-Directed Enzyme Prodrug Therapy: A Promising Approach for a Selective Treatment of Cancer Based on Prodrugs and Monoclonal Antibodies.

Published in:

Chemical Biology & Drug Design, 2009, v. 74, n. 3, p. 205, doi. 10.1111/j.1747-0285.2009.00856.x

By:

Tietze, Lutz F.;
Krewer, Birgit

Publication type:

Article

Direct comparison of Seprafilm versus Adept versus no additive for reducing the risk of small-bowel obstruction in colorectal cancer surgery.

Published in:

Surgery Today, 2013, v. 43, n. 9, p. 995, doi. 10.1007/s00595-013-0490-z

By:

Lee, Won-Suk;
Baek, Jeong;
Lee, Woon

Publication type:

Article

Cost Consequences of Adjuvant Capecitabine, Mayo Clinic and de Gramont Regimens for Stage III Colon Cancer in the French Setting.

Published in:

Oncology, 2007, v. 72, n. 3/4, p. 248, doi. 10.1159/000113016

By:

Douillard, J. Y.;
Tilleul, P.;
Ychou, M.;
Dufour, P.;
Perrocheau, G.;
Seitz, J. F.;
Maes, P.;
Lafuma, A.;
Husseini, F.

Publication type:

Article

Combination immunotherapy: Taking Cancer vaccines to the next Level.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00610

By:

Grenier, Jeremy M.;
Yeung, Stephen T.;
Khanna, Kamal M.

Publication type:

Article

Cost considerations in the treatment of colorectal cancer.

Published in:

2007

By:

Jansman, Frank G .A.;
Postma, Maarten J.;
Brouwers, Jacobus R. B. J.

Publication type:

journal article

Effect of Coadministered Ketoconazole, a Strong Cytochrome P450 3A4 Enzyme Inhibitor, on the Pharmacokinetics of Ciclesonide and its Active Metabolite Desisobutyryl-Ciclesonide.

Published in:

Clinical Pharmacokinetics, 2008, v. 47, n. 5, p. 343, doi. 10.2165/00003088-200847050-00005

By:

Böhmer, Gabriele M.;
Drollmann, Anton;
Gleiter, Christoph H.;
Nave, Rüdiger

Publication type:

Article

Fosamprenavir: Clinical Pharmacokinetics and Drug Interactions of the Amprenavir Prodrug.

Published in:

Clinical Pharmacokinetics, 2006, v. 45, n. 2, p. 137, doi. 10.2165/00003088-200645020-00002

By:

Mary Beth Wire;
Shelton, Mark J.;
Studenberg, Scott

Publication type:

Article

Skin permeation of buprenorphine and its ester prodrugs from lipid nanoparticles: lipid emulsion, nanostructured lipid carriers and solid lipid nanoparticles.

Published in:

Journal of Microencapsulation, 2009, v. 26, n. 8, p. 734, doi. 10.3109/02652040902746679

By:

Wang, Jhi-Joung;
Liu, Kuo-Sheng;
Sung, K. C.;
Tsai, Chia-Yin;
Fang, Jia-You

Publication type:

Article

Uwalnianie granzymu B z leukocytów krwi obwodowej pacjentów z alergią na jad osy -- wpływ swoistej immunoterapii.

Published in:

Alergia Astma Immunologia, 2009, v. 14, n. 1, p. 55

By:

Kłos, Zuzanna;
Kukawiak, Magdalena;
Chałubinksi, Maciej;
Konsińki, Sławomir;
Cieślak, Malgorzara;
Smorawska, Ewa;
Grzelak, Aneta;
Kowalski, Marek L.;
Grzegorczy, Janina

Publication type:

Article

Capecitabine in the treatment of colorectal cancer.

Published in:

Expert Review of Anticancer Therapy, 2007, v. 7, n. 6, p. 803, doi. 10.1586/14737140.7.6.803

By:

Kelly, Claire;
Cassidy, Jim

Publication type:

Article

Antibody-directed enzyme prodrug therapy (ADEPT) for cancer.

Published in:

Expert Review of Anticancer Therapy, 2006, v. 6, n. 10, p. 1421, doi. 10.1586/14737140.6.10.1421

By:

Bagshawe, Kenneth D.

Publication type:

Article

Synthesis and characterization of a novel chitosan based E. coli cytosine deaminase nanocomposite for potential application in prodrug enzyme therapy.

Published in:

Biotechnology Letters, 2011, v. 33, n. 1, p. 153, doi. 10.1007/s10529-010-0416-4

By:

Yata, Vinod;
Ghosh, Siddhartha

Publication type:

Article

Plasma and cerebrospinal fluid pharmacokinetics of nelarabine in nonhuman primates.

Published in:

Cancer Chemotherapy & Pharmacology, 2007, v. 59, n. 6, p. 743, doi. 10.1007/s00280-006-0328-0

By:

Berg, Stacey L.;
Brueckner, Claudia;
Nuchtern, Jed G.;
Dauser, Robert;
McGuffey, Leticia;
Blaney, Susan M.

Publication type:

Article

Trial watch: Immunotherapy shows promise in Phase III neuroblastoma trial.

Published in:: Nature Reviews Drug Discovery, 2009, v. 8, n. 8, p. 604, doi. 10.1038/nrd2951
Publication type:: Article

Prodrugs: design and clinical applications.

Published in:

Nature Reviews Drug Discovery, 2008, v. 7, n. 3, p. 255, doi. 10.1038/nrd2468

By:

Rautio, Jarkko;
Kumpulainen, Hanna;
Heimbach, Tycho;
Oliyai, Reza;
Oh, Dooman;
Järvinen, Tomi;
Savolainen, Jouko

Publication type:

Article

Synthesis of Piperazinylalkyl Ester Prodrugs of Ketorolac and their In Vitro Evaluation for Transdermal Delivery.

Published in:

Drug Development & Industrial Pharmacy, 2008, v. 34, n. 10, p. 1054, doi. 10.1080/03639040801946681

By:

Qandil, Amjad;
Al-Nabulsi, Soraya;
Al-Taani, Bashar;
Tashtoush, Bassam

Publication type:

Article

Evaluation of Cell Permeation of a Potent 5α-Reductase Inhibitor Using MALDI-TOF MS.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2004, v. 19, n. 5, p. 425, doi. 10.1080/14756360410001733739

By:

Mathur, Sonal;
Picard, Frank;
Dossou, Ulrich;
Barassin, Catherine;
Seidel, Stefanie B.;
Min-Jung Kang;
Hartmann, Rolf W.

Publication type:

Article

Natural and synthetic poly(malic acid)-based derivates: a family of versatile biopolymers for the design of drug nanocarriers*.

Published in:

Journal of Drug Targeting, 2014, v. 22, n. 7, p. 556, doi. 10.3109/1061186X.2014.936871

By:

Loyer, Pascal;
Cammas-Marion, Sandrine

Publication type:

Article

Prasugrel.

Published in:

Formulary, 2008, v. 43, n. 11, p. 402

By:

Schilling, Jessica M.;
Kalus, James S.

Publication type:

Article

Clinical Pharmacokinetics of XP13512, a Novel Transported Prodrug of Gabapentin.

Published in:

Journal of Clinical Pharmacology, 2008, v. 48, n. 12, p. 1378, doi. 10.1177/0091270008322909

By:

Cundy, Kenneth C.;
Sastry, Srikonda;
Wendy Luo;
Joan Zou;
Moors, Tristen L.;
Canafax, Daniel M.

Publication type:

Article

Use of <sup> 11</sup>C-methionine PET to monitor the effects of temozolomide chemotherapy in malignant gliomas.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2006, v. 33, n. 5, p. 516, doi. 10.1007/s00259-005-0002-5

By:

Galldiks, Norbert;
Kracht, Lutz W.;
Burghaus, Lothar;
Thomas, Anne;
Jacobs, Andreas H.;
Heiss, Wolf-Dieter;
Herholz, Karl

Publication type:

Article

Chronic N-acetylcysteine after cocaine self-administration produces enduring reductions in drug-seeking.

Published in:

Neuropsychopharmacology, 2012, v. 37, n. 1, p. 298, doi. 10.1038/npp.2011.164

By:

Reichel, Carmela M;
See, Ronald E

Publication type:

Article

The development and psychometric analyses of ADEPT: an instrument for assessing the interactions between doctors and their elderly patients.

Published in:

2005

By:

Teresi, Jeanne A.;
Ramírez, Mildred;
Ocepek-Welikson, Katja;
Cook, Mary Ann;
Ramírez, Mildred

Publication type:

journal article

An Experimental Test of Retention in Residential and Outpatient Programs.

Published in:

American Journal of Drug & Alcohol Abuse, 1994, v. 20, n. 3, p. 331, doi. 10.3109/00952999409106018

By:

Bell, David C.;
Williams, Mark L.;
Nelson, Robin;
Spence2, Richard T.

Publication type:

Article

Icodextrin reduces adhesion formation following gynecological surgery in rabbits.

Published in:

Iranian Journal of Reproductive Medicine, 2011, v. 9, n. 3, p. 187

By:

Khani, Behnaz;
Bahrami, Nahid;
Mehrabian, Ferdous;
Naeni, Hormoz Naderi

Publication type:

Article

Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression.

Published in:

2019

By:

Poncette, Lucia;
Xiaojing Chen;
Lorenz, Felix K. M.;
Blankenstein, Thomas;
Chen, Xiaojing;
Lorenz, Felix Km

Publication type:

journal article

Tailoring the AIE Chromogen 2-(2-Hydroxyphenyl)benzothiazole for Use in Enzyme-Triggered Molecular Brachytherapy.

Published in:

Molecules, 2022, v. 27, n. 24, p. 8682, doi. 10.3390/molecules27248682

By:

Wu, Zhiyuan;
Dou, Jinghuai;
Nguyen, Kathy-Uyen;
Eppley, Jayden C.;
Siwawannapong, Kittipan;
Zhang, Yunlong;
Lindsey, Jonathan S.

Publication type:

Article

Anticancer Inhibitors.

Published in:

Molecules, 2022, v. 27, n. 14, p. N.PAG, doi. 10.3390/molecules27144650

By:

Ammazzalorso, Alessandra;
Fantacuzzi, Marialuigia

Publication type:

Article

Coupling of a Novel TIMP3 Peptide to Carboxypeptidase G2 for Pro-Drug Activation at the Tumour Site.

Published in:

Molecules, 2021, v. 26, n. 3, p. 625, doi. 10.3390/molecules26030625

By:

Aldughaim, Mohammed S.;
Alsaffar, Fatimah;
Barker, Michael D.;
Kokotos, George;
Duarte, Iola F.

Publication type:

Article

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY EVALUATION OF NEW SULFAMETHOXAZOLE-PHOSPHATE ESTER PRODRUGS AND THEIR RELEASE AT DIFFERENT ACIDIC MEDIA.

Published in:

Biochemical & Cellular Archives, 2021, v. 21, n. 1, p. 433

By:

Eraibi, Fatima Abdulkareem;
Hameed, Ayad Saadi

Publication type:

Article

Recombinant horseradish peroxidase variants for targeted cancer treatment.

Published in:

Cancer Medicine, 2016, v. 5, n. 6, p. 1194, doi. 10.1002/cam4.668

By:

Bonifert, Günther;
Folkes, Lisa;
Gmeiner, Christoph;
Dachs, Gabi;
Spadiut, Oliver

Publication type:

Article

Azathioprine: a guide for the management of dermatology patients.

Published in:

Dermatologic Therapy, 2007, v. 20, n. 4, p. 206, doi. 10.1111/j.1529-8019.2007.00134.x

By:

Wise, Melissa;
Callen, Jeffrey P.

Publication type:

Article

A REVIEW ON PRODRUG.

Published in:

Pharma Science Monitor, 2015, v. 6, n. 2, p. 103

By:

Jadhav, Kiran B.;
Khirnar, Harsha R.;
Ishi, Harshada S.;
Borse, S. L.;
Borse, L. B.;
Pawar, S. P.

Publication type:

Article

A reply.

Published in:

Anaesthesia, 2012, v. 67, n. 4, p. 433, doi. 10.1111/j.1365-2044.2012.07113_2.x

By:

Pandit, J. J.;
Popat, M. T.;
Cook, T. M.;
Wilkes, A. R.;
Groom, P.;
Cooke, H.;
Kapila, A.;
O'Sullivan, E.

Publication type:

Article

Prodrugs of aza nucleosides based on proton transfer reaction.

Published in:

Journal of Computer-Aided Molecular Design, 2010, v. 24, n. 12, p. 961, doi. 10.1007/s10822-010-9389-6

By:

Karaman, Rafik

Publication type:

Article

Unmasking the immune recognition of prostate cancer with CTLA4 blockade.

Published in:

2012

By:

Kwek, Serena S.;
Cha, Edward;
Fong, Lawrence

Publication type:

Opinion

Salvestrols: A New Perspective in Nutritional Research.

Published in:

Journal of Orthomolecular Medicine, 2007, v. 22, n. 1, p. 39

By:

Tan, Hoon L.;
Butler, Paul C.;
Burke, M. Danny;
Potter, Gerard A.

Publication type:

Article

Activation of CD95L fusion protein prodrugs by tumor-associated proteases.

Published in:

Cell Death & Differentiation, 2007, v. 14, n. 4, p. 765, doi. 10.1038/sj.cdd.4402051

By:

Watermann, I.;
Gerspach, J.;
Lehne, M.;
Seufert, J.;
Schneider, B.;
Pfizenmaier, K.;
Wajant, H.

Publication type:

Article

Alterations in tumor necrosis factor signaling pathways are associated with cytotoxicity and resistance to taxanes: a study in isogenic resistant tumor cells.

Published in:

2012

By:

Sprowl, Jason A;
Reed, Kerry;
Armstrong, Stephen R;
Lanner, Carita;
Guo, Baoqing;
Kalatskaya, Irina;
Stein, Lincoln;
Hembruff, Stacey L;
Tam, Adam;
Parissenti, Amadeo M

Publication type:

journal article