Results
Title

In Brief.

Abstract

The article offers news briefs on health-related discoveries. Two new classes of small molecules were discovered which disrupted the distinct regulatory of Wnt-dependent signaling proteins in tissue homeostasis and cancer. Disrupting functional interactions between platelet chemokines suppresses atherosclerosis but directly antagonize chemokine receptors to immunological side effects. The use of mutant phosphoinositide 3-kinase and mammalian target of rapamycin may lead to tumour regression.

Subjects

MEDICAL sciences; THERAPEUTICS; WNT proteins; CANCER treatment; ATHEROSCLEROSIS treatment; CHEMOKINES

Publication

Nature Reviews Drug Discovery, 2009, Vol 8, Issue 2, p110

ISSN

1474-1776

Publication type

Academic Journal

DOI

10.1038/nrd2812