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Title

Pemetrexed disodium.

Authors

Muhsin, Mohamed; Gricks, Clair; Kirkpatrick, Peter

Abstract

In February 2004, pemetrexed disodium (Alimta; Eli Lilly), an anticancer drug that targets folate-dependent reactions that are essential for cell proliferation, became the first drug to be approved by the FDA for the treatment of the rare cancer malignant pleural mesothelioma. Its accelerated approval for the second-line treatment of non-small-cell lung cancer, which will considerably increase its market potential, followed in August 2004.

Subjects

UNITED States; ANTINEOPLASTIC agents; SODIUM compounds; DRUG approval; MESOTHELIOMA; LUNG cancer treatment; THERAPEUTICS

Publication

Nature Reviews Drug Discovery, 2004, Vol 3, Issue 10, p825

ISSN

1474-1776

Publication type

Academic Journal

DOI

10.1038/nrd1528

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