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Title

Cardiovascular disease: Another string to LXR's bow.

Authors

Kirkpatrick, Peter

Abstract

Discusses the role of liver X receptors (LXR) in reducing atherosclerosis. Effects of LXR activation on the expression of genes involved in the immune system; Role of macrophages in atherosclerosis; Reduction in the production of inflammatory mediators.

Subjects

ATHEROSCLEROSIS treatment; GENE expression; MACROPHAGES

Publication

Nature Reviews Drug Discovery, 2003, Vol 2, Issue 3, p172

ISSN

1474-1776

Publication type

Academic Journal

DOI

10.1038/nrd1050

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