Works matching AU Vadolas, Jim
Results: 24
Iron induces blood-brain barrier alteration contributing to cognitive impairment in β-thalassaemia mice.
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- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-024-84395-z
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Cognitive impairment and hippocampal neuronal damage in β-thalassaemia mice.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-60459-y
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A reduced curcuminoid analog as a novel inducer of fetal hemoglobin.
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- Annals of Hematology, 2013, v. 92, n. 3, p. 379, doi. 10.1007/s00277-012-1604-1
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ErythRED, a hESC line enabling identification of erythroid cells.
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- Nature Methods, 2009, v. 6, n. 9, p. 659, doi. 10.1038/nmeth.1364
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Intranasal immunization with yeast-expressed 19 kD carboxyl-terminal fragment of Plasmodium yoelii merozoite surface protein-1 (yMSP1[sub 19]) induces protective immunity to blood stage malaria infection in mice.
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- Parasite Immunology, 1998, v. 20, n. 9, p. 413, doi. 10.1046/j.1365-3024.1998.00161.x
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Cellular genomic reporter assays for screening and evaluation of inducers of fetal hemoglobin.
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- Human Molecular Genetics, 2004, v. 13, n. 2, p. 223, doi. 10.1093/hmg/ddh023
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Animal models of β-hemoglobinopathies: utility and limitations.
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- Journal of Blood Medicine, 2016, v. 7, p. 263, doi. 10.2147/JBM.S87955
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Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin.
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- Nature Communications, 2015, v. 6, n. 5, p. 7085, doi. 10.1038/ncomms8085
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Impaired neutrophil extracellular trap formation in β-thalassaemia/HbE.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-06036-7
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A comprehensive study of immune function and immunophenotyping of white blood cells from β‐thalassaemia/HbE patients on hydroxyurea supports the safety of the drug.
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- British Journal of Haematology, 2023, v. 200, n. 3, p. 367, doi. 10.1111/bjh.18508
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SLN124, a GalNac‐siRNA targeting transmembrane serine protease 6, in combination with deferiprone therapy reduces ineffective erythropoiesis and hepatic iron‐overload in a mouse model of β‐thalassaemia.
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- British Journal of Haematology, 2021, v. 194, n. 1, p. 200, doi. 10.1111/bjh.17428
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Elevated levels of circulating monocytic myeloid derived suppressor cells in splenectomised β‐thalassaemia/HbE patients.
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- British Journal of Haematology, 2020, v. 191, n. 3, p. e72, doi. 10.1111/bjh.17012
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Increased ferritin levels in non‐transfusion‐dependent β°‐thalassaemia/HbE are associated with reduced CXCR2 expression and neutrophil migration.
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- British Journal of Haematology, 2020, v. 189, n. 1, p. 187, doi. 10.1111/bjh.16295
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An in vivo model for analysis of developmental erythropoiesis and globin gene regulation.
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- FASEB Journal, 2014, v. 28, n. 5, p. 2306, doi. 10.1096/fj.13-246637
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Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β‐like globin genes.
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- FASEB Journal, 2014, v. 28, n. 4, p. 1610, doi. 10.1096/fj.13-242669
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Generation of a genomic reporter assay system for analysis of γ- and β-globin gene regulation.
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- FASEB Journal, 2012, v. 26, n. 4, p. 1736, doi. 10.1096/fj.11-199356
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Engineering EGFP reporter constructs into a 200 kb human β-globin BAC clone using GET Recombination.
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- Nucleic Acids Research, 2000, v. 28, n. 18, p. e84, doi. 10.1093/nar/28.18.e84
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Accumulation of lipid peroxidation-derived DNA lesions in iron-overloaded thalassemic mouse livers: Comparison with levels in the lymphocytes of thalassemia patients.
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- International Journal of Cancer, 2009, v. 125, n. 4, p. 759, doi. 10.1002/ijc.24412
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Development of model systems for β-thalassaemia.
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- Thalassemia Reports, 2013, v. 3, n. 1s, p. 102, doi. 10.4081/thal.2013.s1.e41
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The role of macrophages in the induction and regulation of immunity elicited by exogenous antigens.
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- European Journal of Immunology, 1998, v. 28, n. 2, p. 479, doi. 10.1002/(SICI)1521-4141(199802)28:02<479::AID-IMMU479>3.0.CO;2-R
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Intranasal immunization with liposomes induces strong mucosal immune responses in mice.
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- European Journal of Immunology, 1995, v. 25, n. 4, p. 969, doi. 10.1002/eji.1830250417
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A 191-kb genomic fragment containing the human α-globin locus can rescue α-thalassemic mice.
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- Mammalian Genome, 2005, v. 16, n. 11, p. 847, doi. 10.1007/s00335-005-0089-9
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Trienone analogs of curcuminoids induce fetal hemoglobin synthesis via demethylation at Gγ-globin gene promoter.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-87738-2
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Gene induction for the treatment of methylmalonic aciduria.
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- Journal of Gene Medicine, 2009, v. 11, n. 4, p. 361, doi. 10.1002/jgm.1297
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