Works matching DE "PARKIN (Protein)"

Results: 268

Interplay between α-synuclein and parkin genes: Insights of Parkinson's disease.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09520-7

By:

Sharma, Kajal;
Chib, Shivani;
Gupta, Aniket;
Singh, Randhir;
Chalotra, Rishabh

Publication type:

Article

Parkin exerts the tumor‐suppressive effect through targeting mitochondria.

Published in:

Medicinal Research Reviews, 2023, v. 43, n. 4, p. 855, doi. 10.1002/med.21938

By:

Sun, Xin;
Ye, Guiqin;
Mai, Yuanyuan;
Shu, Yuhan;
Wang, Lei;
Zhang, Jianbin

Publication type:

Article

Distinct phosphorylation signals drive acceptor versus free ubiquitin chain targeting by parkin.

Published in:

Biochemical Journal, 2022, v. 479, n. 6, p. 751, doi. 10.1042/BCJ20210741

By:

Dunkerley, Karen M.;
Rintala-Dempsey, Anne C.;
Salzano, Giulia;
Tadayon, Roya;
Hadi, Dania;
Barber, Kathryn R.;
Walden, Helen;
Shaw, Gary S.

Publication type:

Article

Investigation of USP30 inhibition to enhance Parkin-mediated mitophagy: tools and approaches.

Published in:

Biochemical Journal, 2021, v. 478, n. 23, p. 4099, doi. 10.1042/BCJ20210508

By:

Tsefou, Eliona;
Walker, Alison S.;
Clark, Emily H.;
Hicks, Amy R.;
Luft, Christin;
Kunitoshi Takeda;
Watanabe, Toru;
Ramazio, Bianca;
Staddon, James M.;
Briston, Thomas;
Ketteler, Robin

Publication type:

Article

Pink1-Mediated Chondrocytic Mitophagy Contributes to Cartilage Degeneration in Osteoarthritis.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 11, p. 1849, doi. 10.3390/jcm8111849

By:

Shin, Hyo Jung;
Park, Hyewon;
Shin, Nara;
Kwon, Hyeok Hee;
Yin, Yuhua;
Hwang, Jeong-Ah;
Song, Hee-Jung;
Kim, Jinhyun;
Kim, Dong Woon;
Beom, Jaewon

Publication type:

Article

Dual mechanism of DICER downregulation facilitates cancer metastasis.

Published in:

Molecular & Cellular Oncology, 2018, v. 5, n. 5, p. 1, doi. 10.1080/23723556.2018.1472056

By:

Lai, Hui-Huang;
Chen, Pai-Sheng

Publication type:

Article

Activation of Pink1/Parkin-mediated mitochondrial autophagy alleviates exertional heat stroke-induced acute lung injury in rats.

Published in:

Clinical Hemorheology & Microcirculation, 2024, v. 88, n. 1, p. 13, doi. 10.3233/CH-242100

By:

Wang, Jiaxing;
Sun, Zhengzhong;
Jiang, Liya;
Xuan, Lyv;
Ma, Yunya;
Wang, Jiao;
Gu, Yan;
Zhang, Yuxiang

Publication type:

Article

Bu-Yin-Qian-Zheng Formula Ameliorates MPP+-Induced Mitochondrial Dysfunction in Parkinson's Disease via Parkin.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.577017

By:

Ma, Hao-Jie;
Gai, Cong;
Chai, Yuan;
Feng, Wan-Di;
Cheng, Cui-Cui;
Zhang, Jin-Kun;
Zhang, Yu-Xin;
Yang, Lu-Ping;
Guo, Zhen-Yu;
Gao, Yu-Shan;
Sun, Hong-Mei

Publication type:

Article

Antitumor Actions of Intratumoral Delivery of Membrane-Fused Mitochondria in a Mouse Model of Triple-Negative Breast Cancers.

Published in:

OncoTargets & Therapy, 2020, v. 13, p. 5241, doi. 10.2147/OTT.S238143

By:

Chang, Jui-Chih;
Chang, Huei-Shin;
Wu, Yao-Chung;
Cheng, Wen-Ling;
Lin, Ta-Tsung;
Chang, Hui-Ju;
Chen, Shou-Tung;
Liu, Chin-San

Publication type:

Article

Deconstructing the molecular genetics behind the PINK1/Parkin axis in Parkinson's disease using Drosophila melanogaster as a model organism.

Published in:

Egyptian Journal of Medical Human Genetics, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s43042-021-00208-2

By:

Ganesan, Suchita;
Parvathi, Venkatachalam Deepa

Publication type:

Article

Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice.

Published in:

Molecular Brain, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-6606-6-35

By:

Ageta-Ishihara, Natsumi;
Yamakado, Hodaka;
Morita, Takao;
Hattori, Satoko;
Takao, Keizo;
Miyakawa, Tsuyoshi;
Takahashi, Ryosuke;
Kinoshita, Makoto

Publication type:

Article

Therapeutic Implications and Regulations of Protein Post-translational Modifications in Parkinsons Disease.

Published in:

Cellular & Molecular Neurobiology, 2024, v. 44, n. 1, p. 1, doi. 10.1007/s10571-024-01471-8

By:

Mishra, Twinkle;
Singh, Shareen;
Singh, Thakur Gurjeet

Publication type:

Article

Targeting Mitochondria as a Therapeutic Approach for Parkinson's Disease.

Published in:

Cellular & Molecular Neurobiology, 2023, v. 43, n. 4, p. 1499, doi. 10.1007/s10571-022-01265-w

By:

Abrishamdar, Maryam;
Jalali, Maryam Sadat;
Farbood, Yaghoob

Publication type:

Article

Pathogenesis of Parkinson's disease: from hints from monogenic familial PD to biomarkers.

Published in:

Journal of Neural Transmission, 2024, v. 131, n. 6, p. 709, doi. 10.1007/s00702-024-02747-5

By:

Hattori, Nobutaka;
Funayama, Manabu;
Imai, Yuzuru;
Hatano, Taku

Publication type:

Article

Proteomic Analysis of Parkin Isoforms Expression in Different Rat Brain Areas.

Published in:

Protein Journal, 2016, v. 35, n. 5, p. 354, doi. 10.1007/s10930-016-9679-5

By:

D'Amico, Agata;
Maugeri, Grazia;
Reitano, Rita;
Cavallaro, Sebastiano;
D'Agata, Velia

Publication type:

Article

Hepatitis C Virus Induces the Mitochondrial Translocation of Parkin and Subsequent Mitophagy.

Published in:

PLoS Pathogens, 2013, v. 9, n. 3, p. 1, doi. 10.1371/journal.ppat.1003285

By:

Seong-Jun Kim;
Syed, Gulam H.;
Siddiqui, Aleem

Publication type:

Article

Upregulated Parkin expression protects mitochondrial homeostasis in DJ-1 konckdown cells and cells overexpressing the DJ-1 L166P mutation.

Published in:

Molecular & Cellular Biochemistry, 2014, v. 387, n. 1/2, p. 187, doi. 10.1007/s11010-013-1884-3

By:

Chang, Chunyan;
Wu, Guolu;
Gao, Peiye;
Yang, Ling;
Liu, Wen;
Zuo, Ji

Publication type:

Article

Erratum: Mechanism of phospho-ubiquitin-induced PARKIN activation.

Published in:

2015

By:

Wauer, Tobias;
Simicek, Michal;
Schubert, Alexander;
Komander, David

Publication type:

Correction Notice

PARKIN is not required to sustain OXPHOS function in adult mammalian tissues.

Published in:

NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00707-0

By:

Filograna, Roberta;
Gerlach, Jule;
Choi, Hae-Na;
Rigoni, Giovanni;
Barbaro, Michela;
Oscarson, Mikael;
Lee, Seungmin;
Tiklova, Katarina;
Ringnér, Markus;
Koolmeister, Camilla;
Wibom, Rolf;
Riggare, Sara;
Nennesmo, Inger;
Perlmann, Thomas;
Wredenberg, Anna;
Wedell, Anna;
Motori, Elisa;
Svenningsson, Per;
Larsson, Nils-Göran

Publication type:

Article

脉络宁注射液干预挤压伤综合征模型猪线粒体自噬及 PINK1/Parkin 通路的变化.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2021, v. 25, n. 17, p. 2676, doi. 10.3969/j.issn.2095-4344.3157

By:

陈天贵;
高磊;
李天博;
王江宁

Publication type:

Article

Phosphorylated ubiquitin chain is the genuine Parkin receptor.

Published in:

Journal of Cell Biology, 2015, v. 209, n. 1, p. 111, doi. 10.1083/jcb.201410050

By:

Kei Okatsu;
Fumika Koyano;
Mayumi Kimura;
Hidetaka Kosako;
Yasushi Saeki;
Keiji Tanaka;
Noriyuki Matsuda

Publication type:

Article

PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding.

Published in:

Journal of Cell Biology, 2013, v. 200, n. 2, p. 163, doi. 10.1083/jcb.201210111

By:

Lazarou, Michael;
Narendra, Derek P.;
Jin, Seok Min;
Tekle, Ephrem;
Banerjee, Soojay;
Youle, Richard J.

Publication type:

Article

Increase of Parkin and ATG5 plasmatic levels following perinatal hypoxic-ischemic encephalopathy.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-11870-w

By:

Tarocco, Anna;
Morciano, Giampaolo;
Perrone, Mariasole;
Cafolla, Claudia;
Ferrè, Cristina;
Vacca, Tiziana;
Pistocchi, Ginevra;
Meneghin, Fabio;
Cocchi, Ilaria;
Lista, Gianluca;
Cetin, Irene;
Greco, Pantaleo;
Garani, Giampaolo;
Stella, Marcello;
Natile, Miria;
Ancora, Gina;
Savarese, Immacolata;
Campi, Francesca;
Bersani, Iliana;
Dotta, Andrea

Publication type:

Article

An assessment of the rescue action of resveratrol in parkin loss of function-induced oxidative stress in Drosophila melanogaster.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07909-7

By:

Adedara, Adeola O.;
Babalola, Ayoade D.;
Stephano, Flora;
Awogbindin, Ifeoluwa O.;
Olopade, James O.;
Rocha, João B. T.;
Whitworth, Alexander J.;
Abolaji, Amos O.

Publication type:

Article

An altered microbiome in a Parkinson's disease model Drosophila melanogaster has a negative effect on development.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-02624-1

By:

Parker-Character, Jade;
Hager, David R.;
Call, Tanner B.;
Pickup, Zachary S.;
Turnbull, Scott A.;
Marshman, Evan M.;
Korch, Shaleen B.;
Chaston, John M.;
Call, Gerald B.

Publication type:

Article

AMPK activates Parkin independent autophagy and improves post sepsis immune defense against secondary bacterial lung infections.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90573-0

By:

Bone, Nathaniel B.;
Becker, Eugene J.;
Husain, Maroof;
Jiang, Shaoning;
Zmijewska, Anna A.;
Park, Dae-Won;
Chacko, Balu;
Darley-Usmar, Victor;
Grégoire, Murielle;
Tadie, Jean-Marc;
Thannickal, Victor J.;
Zmijewski, Jaroslaw W.

Publication type:

Article

Triggering of Parkin Mitochondrial Translocation in Mitophagy: Implications for Liver Diseases.

Published in:

Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00100

By:

Nabil Eid;
Yuko Ito;
Yoshinori Otsuki

Publication type:

Article

Dysregulation of Parkin-mediated mitophagy in thyroid Hürthle cell tumors.

Published in:

Carcinogenesis, 2015, v. 36, n. 11, p. 1407, doi. 10.1093/carcin/bgv122

By:

Junguee Lee;
Sujin Ham;
Min Hee Lee;
Soung Jung Kim;
Ji Hoon Park;
Seong Eun Lee;
Joon Young Chang;
Kyong Hye Joung;
Tae Yong Kim;
Jin Man Kim;
Hae Joung Su;
Gi Ryang Kweon;
Young Suk Jo;
Koon Soon Kim;
Young Kee Shong;
Gasparre, Giuseppe;
Jong Kyeong Chung;
Porcelli, Anna Maria;
Minho Shong

Publication type:

Article

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32689-z

By:

Zhai, Yansheng;
Huang, Xiaoyan;
Zhang, Keren;
Huang, Yuchen;
Jiang, Yanlong;
Cui, Jingwei;
Zhang, Zhe;
Chiu, Cookson K. C.;
Zhong, Weiye;
Li, Gang

Publication type:

Article

Mitochondrial Quality Control in Aging and Heart Failure: Influence of Ketone Bodies and Mitofusin-Stabilizing Peptides.

Published in:

Frontiers in Physiology, 2019, p. N.PAG, doi. 10.3389/fphys.2019.00382

By:

Thai, Phung N.;
Seidlmayer, Lea K.;
Miller, Charles;
Ferrero, Maura;
Dorn II, Gerald W.;
Schaefer, Saul;
Bers, Donald M.;
Dedkova, Elena N.

Publication type:

Article

Parkin mediates mitophagy during beige-to-white fat conversion.

Published in:

Science Signaling, 2018, v. 11, n. 527, p. 1, doi. 10.1126/scisignal.aat1082

By:

Sarraf, Shireen A.;
Youle, Richard J.

Publication type:

Article

PINK1-Parkin-Mediated Mitophagy Protects Mitochondrial Integrity and Prevents Metabolic Stress-Induced Endothelial Injury.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132499

By:

Wu, Weiwei;
Xu, Hao;
Wang, Zemin;
Mao, Yun;
Yuan, Liangshuai;
Luo, Wei;
Cui, Zhaoqiang;
Cui, Taixing;
Wang, Xing Li;
Shen, Ying H.

Publication type:

Article

Correction: Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0118526

By:

null, null

Publication type:

Article

Correction: Cell-Permeable Parkin Proteins Suppress Parkinson Disease-Associated Phenotypes in Cultured Cells and Animals.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0116242

By:

null, null

Publication type:

Article

Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114216

By:

Rial, Daniel;
Castro, Adalberto A.;
Machado, Nuno;
Garção, Pedro;
Gonçalves, Francisco Q.;
Silva, Henrique B.;
Tomé, Ângelo R.;
Köfalvi, Attila;
Corti, Olga;
Raisman-Vozari, Rita;
Cunha, Rodrigo A.;
Prediger, Rui D.

Publication type:

Article

Parkin (PARK 2) Mutations Are Rare in Czech Patients with Early-Onset Parkinson's Disease.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107585

By:

Fiala, Ondrej;
Zahorakova, Daniela;
Pospisilova, Lenka;
Kucerova, Jana;
Matejckova, Milada;
Martasek, Pavel;
Roth, Jan;
Ruzicka, Evzen

Publication type:

Article

Cell-Permeable Parkin Proteins Suppress Parkinson Disease-Associated Phenotypes in Cultured Cells and Animals.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102517

By:

Duong, Tam;
Kim, Jaetaek;
Ruley, H. Earl;
Jo, Daewoong

Publication type:

Article

Tissue- and Cell-Specific Mitochondrial Defect in Parkin-Deficient Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099898

By:

Damiano, Maria;
Gautier, Clément A.;
Bulteau, Anne-Laure;
Ferrando-Miguel, Rosa;
Gouarne, Caroline;
Paoli, Marc Giraudon;
Pruss, Rebecca;
Auchère, Françoise;
L'Hermitte-Stead, Caroline;
Bouillaud, Frédéric;
Brice, Alexis;
Corti, Olga;
Lombès, Anne

Publication type:

Article

Autophagy Inhibitor LRPPRC Suppresses Mitophagy through Interaction with Mitophagy Initiator Parkin.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094903

By:

Zou, Jing;
Yue, Fei;
Li, Wenjiao;
Song, Kun;
Jiang, Xianhan;
Yi, Jinglin;
Liu, Leyuan

Publication type:

Article

Unaltered Striatal Dopamine Release Levels in Young Parkin Knockout, Pink1 Knockout, DJ-1 Knockout and LRRK2 R1441G Transgenic Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094826

By:

Sanchez, Gonzalo;
Varaschin, Rafael K.;
Büeler, Hansruedi;
Marcogliese, Paul C.;
Park, David S.;
Trudeau, Louis-Eric

Publication type:

Article

Correction: Behavioral and Neurotransmitter Abnormalities in Mice Deficient for Parkin, DJ-1 and Superoxide Dismutase.

Published in:: PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0091128
Publication type:: Article

Behavioral and Neurotransmitter Abnormalities in Mice Deficient for Parkin, DJ-1 and Superoxide Dismutase.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084894

By:

Hennis, Meghan R.;
Seamans, Katherine W.;
Marvin, Marian A.;
Casey, Bradford H.;
Goldberg, Matthew S.

Publication type:

Article

Ubiquitination Increases Parkin Activity to Promote Autophagic α-Synuclein Clearance.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083914

By:

Lonskaya, Irina;
Desforges, Nicole M.;
Hebron, Michaeline L.;
Moussa, Charbel E-H.

Publication type:

Article

Profiling of Parkin-Binding Partners Using Tandem Affinity Purification.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078648

By:

Zanon, Alessandra;
Rakovic, Aleksandar;
Blankenburg, Hagen;
Doncheva, Nadezhda T.;
Schwienbacher, Christine;
Serafin, Alice;
Alexa, Adrian;
Weichenberger, Christian X.;
Albrecht, Mario;
Klein, Christine;
Hicks, Andrew A.;
Pramstaller, Peter P.;
Domingues, Francisco S.;
Pichler, Irene

Publication type:

Article

Proteasome Inhibition Promotes Parkin-Ubc13 Interaction and Lysine 63-Linked Ubiquitination.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0073235

By:

Lim, Grace G. Y.;
Chew, Katherine C. M.;
Ng, Xiao-Hui;
Henry-Basil, Adeline;
Sim, Roy W. X.;
Tan, Jeanne M. M.;
Chai, Chou;
Lim, Kah-Leong

Publication type:

Article

Overexpression of Parkin Ameliorates Dopaminergic Neurodegeneration Induced by 1- Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039953

By:

Minjuan Bian;
Jie Liu;
Xiaoqi Hong;
Mei Yu;
Yufang Huang;
Zhejin Sheng;
Jian Fei;
Fang Huang

Publication type:

Article

Small, N-Terminal Tags Activate Parkin E3 Ubiquitin Ligase Activity by Disrupting Its Autoinhibited Conformation.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034748

By:

Burchell, Lynn;
Chaugule, Viduth K.;
Walden, Helen

Publication type:

Article

Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1.

Published in:

PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0020975

By:

Chengqun Huang;
Allen M. Andres;
Eric P. Ratliff;
Genaro Hernandez;
Pamela Lee;
Roberta A. Gottlieb

Publication type:

Article

Discovery of Small Molecule PARKIN Activator from Antipsychotic/Anti-neuropsychiatric Drugs as Therapeutics for PD: an In Silico Repurposing Approach.

Published in:

Applied Biochemistry & Biotechnology, 2023, v. 195, n. 10, p. 5980, doi. 10.1007/s12010-023-04376-2

By:

Ibrahim, Abdulwasiu;
Ipinloju, Nureni;
Atasie, Nkechi Hope;
Babalola, Rahmotallah Mosunmola;
Muhammad, Suleiman Alhaji;
Oyeneyin, Oluwatoba Emmanuel

Publication type:

Article

Study of the Effects of Nicotine and Caffeine for the Treatment of Parkinson's Disease.

Published in:

Applied Biochemistry & Biotechnology, 2023, v. 195, n. 1, p. 639, doi. 10.1007/s12010-022-04155-5

By:

Biswas, Sima;
Bagchi, Angshuman

Publication type:

Article