Works matching DE "RNA polymerase II"

Results: 1416

CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II-transcribed genes.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 5, p. 396, doi. 10.1038/nsmb.3000

By:

Laitem, Clélia;
Zaborowska, Justyna;
Isa, Nur F;
Kufs, Johann;
Dienstbier, Martin;
Murphy, Shona

Publication type:

Article

A bumpy road for RNA polymerase II.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 5, p. 353, doi. 10.1038/nsmb.3020

By:

Giono, Luciana E;
Kornblihtt, Alberto R

Publication type:

Article

Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 4, p. 319, doi. 10.1038/nsmb.2982

By:

Dhir, Ashish;
Dhir, Somdutta;
Proudfoot, Nick J;
Jopling, Catherine L

Publication type:

Article

Spliced integrated retrotransposed element (SpIRE) formation in the human genome.

Published in:

PLoS Biology, 2018, v. 16, n. 3, p. 1, doi. 10.1371/journal.pbio.2003067

By:

Larson, Peter A.;
Moldovan, John B.;
Jasti, Naveen;
Kidd, Jeffrey M.;
Beck, Christine R.;
Moran, John V.

Publication type:

Article

Enhancing Auxiliary‐Mediated Native Chemical Ligation at Challenging Junctions with Pyridine Scaffolds.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 68, p. 1, doi. 10.1002/chem.202202065

By:

Trunschke, Sebastian;
Piemontese, Emanuele;
Fuchs, Olaf;
Abboud, Skander;
Seitz, Oliver

Publication type:

Article

Binding of small molecule inhibitors to RNA polymerase-Spt5 complex impacts RNA and DNA stability.

Published in:

Journal of Computer-Aided Molecular Design, 2024, v. 38, n. 1, p. 1, doi. 10.1007/s10822-023-00543-z

By:

Gallardo, Adan;
Dutagaci, Bercem

Publication type:

Article

Insight into the sequence-specific elements leading to increased DNA bending and ligase-mediated circularization propensity by antitumor trabectedin.

Published in:

Journal of Computer-Aided Molecular Design, 2021, v. 35, n. 6, p. 707, doi. 10.1007/s10822-021-00396-4

By:

Mills, Alberto;
Gago, Federico

Publication type:

Article

CDK7 inhibitors as anticancer drugs.

Published in:

Cancer & Metastasis Reviews, 2020, v. 39, n. 3, p. 805, doi. 10.1007/s10555-020-09885-8

By:

Sava, Georgina P.;
Fan, Hailing;
Coombes, R. Charles;
Buluwela, Lakjaya;
Ali, Simak

Publication type:

Article

Talaromyces sedimenticola sp. nov., isolated from the Mariana Trench.

Published in:

Antonie van Leeuwenhoek, 2024, v. 117, n. 1, p. 1, doi. 10.1007/s10482-024-01945-1

By:

Zhou, Hongbo;
Xu, Liting;
Liu, Wenxian;
Ta, Kaiwen;
Wang, Xincun;
Guo, Jianwei;
Luo, Wenxi;
Peng, Zhiyuan;
Huang, Qiaoni;
Wang, Yuguang

Publication type:

Article

Intraspecific nucleotide divergence in Saccharomycodes ludwigii, and proposal of Saccharomycodes pseudoludwigii sp. nov, a new apiculate yeast isolated from China.

Published in:

Antonie van Leeuwenhoek, 2021, v. 114, n. 5, p. 553, doi. 10.1007/s10482-021-01540-8

By:

Wang, Man-Man;
Groenewald, Marizeth;
Wu, Feng;
Guo, Yun-Tong;
Wang, Qi-Ming;
Boekhout, Teun

Publication type:

Article

Two new species of the Fusarium solani species complex isolated from compost and hibiscus (Hibiscus sp.).

Published in:

Antonie van Leeuwenhoek, 2018, v. 111, n. 10, p. 1785, doi. 10.1007/s10482-018-1068-y

By:

Šišić, Adnan;
Al-Hatmi, Abdullah M. S.;
Baćanović-Šišić, Jelena;
Ahmed, Sarah A.;
Dennenmoser, Dominic;
de Hoog, G. Sybren;
Finckh, Maria R.

Publication type:

Article

Interconnected Codons: Unravelling the Epigenetic Significance of Flanking Sequences in CpG Dyads.

Published in:

Journal of Molecular Evolution, 2024, v. 92, n. 3, p. 207, doi. 10.1007/s00239-024-10172-1

By:

Creasey, Leo Douglas;
Tauber, Eran

Publication type:

Article

Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.

Published in:

Nature, 2015, v. 526, n. 7573, p. 453, doi. 10.1038/nature15258

By:

Wiesner, Thomas;
Lee, William;
Obenauf, Anna C.;
Ran, Leili;
Murali, Rajmohan;
Zhang, Qi Fan;
Wong, Elissa W. P.;
Hu, Wenhuo;
Scott, Sasinya N.;
Shah, Ronak H.;
Landa, Iñigo;
Button, Julia;
Lailler, Nathalie;
Sboner, Andrea;
Gao, Dong;
Murphy, Devan A.;
Cao, Zhen;
Shukla, Shipra;
Hollmann, Travis J.;
Wang, Lu

Publication type:

Article

Integrator mediates the biogenesis of enhancer RNAs.

Published in:

Nature, 2015, v. 525, n. 7569, p. 399, doi. 10.1038/nature14906

By:

Lai, Fan;
Gardini, Alessandro;
Zhang, Anda;
Shiekhattar, Ramin

Publication type:

Article

Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.

Published in:

Nature, 2015, v. 523, n. 7562, p. 621, doi. 10.1038/nature14482

By:

Wang, Lanfeng;
Zhou, Yu;
Xu, Liang;
Xiao, Rui;
Lu, Xingyu;
Chen, Liang;
Chong, Jenny;
Li, Hairi;
He, Chuan;
Fu, Xiang-Dong;
Wang, Dong

Publication type:

Article

Cancer: An essential passenger with p53.

Published in:

Nature, 2015, v. 520, n. 7549, p. 626, doi. 10.1038/nature14390

By:

Bradner, James E.

Publication type:

Article

TP53 loss creates therapeutic vulnerability in colorectal cancer.

Published in:

Nature, 2015, v. 520, n. 7549, p. 697, doi. 10.1038/nature14418

By:

Liu, Yunhua;
Zhang, Xinna;
Han, Cecil;
Wan, Guohui;
Huang, Xingxu;
Ivan, Cristina;
Jiang, Dahai;
Rodriguez-Aguayo, Cristian;
Lopez-Berestein, Gabriel;
Rao, Pulivarthi H.;
Maru, Dipen M.;
Pahl, Andreas;
He, Xiaoming;
Sood, Anil K.;
Ellis, Lee M.;
Anderl, Jan;
Lu, Xiongbin

Publication type:

Article

Architecture of the RNA polymerase II-Mediator core initiation complex.

Published in:

Nature, 2015, v. 518, n. 7539, p. 376, doi. 10.1038/nature14229

By:

Plaschka, C.;
Larivière, L.;
Wenzeck, L.;
Seizl, M.;
Hemann, M.;
Tegunov, D.;
Petrotchenko, E. V.;
Borchers, C. H.;
Baumeister, W.;
Herzog, F.;
Villa, E.;
Cramer, P.

Publication type:

Article

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis.

Published in:

Nature Immunology, 2015, v. 16, n. 5, p. 485, doi. 10.1038/ni.3132

By:

Miller, Matthew S;
Rialdi, Alexander;
Ho, Jessica Sook Yuin;
Tilove, Micah;
Martinez-Gil, Luis;
Moshkina, Natasha P;
Peralta, Zuleyma;
Noel, Justine;
Melegari, Camilla;
Maestre, Ana M;
Mitsopoulos, Panagiotis;
Madrenas, Joaquín;
Heinz, Sven;
Benner, Chris;
Young, John A T;
Feagins, Alicia R;
Basler, Christopher F;
Fernandez-Sesma, Ana;
Becherel, Olivier J;
Lavin, Martin F

Publication type:

Article

Long noncoding RNAs in pancreas cancer: from biomarkers to therapeutic targets.

Published in:

Turkish Journal of Medical Sciences, 2023, v. 53, n. 6, p. 1552, doi. 10.55730/1300-0144.5724

By:

GÜZEL TANOĞLU, Esra;
ADIGÜZEL, Seyfure;
TANOĞLU, Alpaslan;
AYDIN, Zehra Betül;
HOCAOĞLU, Gülizar;
EBİNÇ, Samet

Publication type:

Article

In the Driver’s Seat.

Published in:

Journal of Biological Rhythms, 2016, v. 31, n. 1, p. 37, doi. 10.1177/0748730415607321

By:

Montenegro-Montero, Alejandro;
Larrondo, Luis F.

Publication type:

Article

An expansion of phenotype: novel homozygous variant in the MED17 identified in patients with progressive microcephaly and global developmental delay.

Published in:

Journal of Neurogenetics, 2022, v. 36, n. 4, p. 108, doi. 10.1080/01677063.2022.2149748

By:

Rafiullah, Rafiullah;
Albalawi, Alia M.;
Alaradi, Sultan R.;
Alluqmani, Majed;
Mushtaq, Muhammad;
Wali, Abdul;
Basit, Sulman

Publication type:

Article

HSV-1 ICP22 Is a Selective Viral Repressor of Cellular RNA Polymerase II-Mediated Transcription Elongation.

Published in:

Vaccines, 2021, v. 9, n. 10, p. 1054, doi. 10.3390/vaccines9101054

By:

Isa, Nur Firdaus;
Bensaude, Olivier;
Aziz, Nadiah C.;
Murphy, Shona

Publication type:

Article

New link between the RNA polymerase II-CTD and replication stress.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 3, p. 1, doi. 10.1080/23723556.2021.1910008

By:

Landsverk, Helga B.;
Sandquist, Lise E.;
Bay, Lilli T. E.;
Syljuåsen, Randi G.

Publication type:

Article

The protective effect of Metformin/Donepezil in diabetic mice brain: evidence from bioinformatics analysis and experiments.

Published in:

European Review for Medical & Pharmacological Sciences, 2021, v. 25, n. 24, p. 7668

By:

HOU, Y.;
LI, F.-Z.

Publication type:

Article

Elevated long non-coding RNA LINC00958 was associated with metastasis and unfavorable prognosis in gastric cancer.

Published in:

European Review for Medical & Pharmacological Sciences, 2019, v. 23, n. 2, p. 598, doi. 10.26355/eurrev_201901_16872

By:

WANG, W.;
SONG, Z.-J.;
WANG, Y.;
ZHONG, W.-F.;
KANG, P.;
YANG, Y.

Publication type:

Article

Identification of a Specific Inhibitor of Human Scp1 Phosphatase Using the Phosphorylation Mimic Phage Display Method.

Published in:

Catalysts (2073-4344), 2019, v. 9, n. 10, p. 842, doi. 10.3390/catal9100842

By:

Yoshida, Takuya;
Yamazaki, Kazuki;
Imai, Shunta;
Banno, Akinori;
Kaneko, Atsushi;
Furukawa, Kazuhiro;
Chuman, Yoshiro

Publication type:

Article

Double Blast Wave Primary Effect on Synaptic, Glymphatic, Myelin, Neuronal and Neurovascular Markers.

Published in:

Brain Sciences (2076-3425), 2023, v. 13, n. 2, p. 286, doi. 10.3390/brainsci13020286

By:

Iacono, Diego;
Murphy, Erin K.;
Stimpson, Cheryl D.;
Leonessa, Fabio;
Perl, Daniel P.

Publication type:

Article

Mechanisms and Functions of the RNA Polymerase II General Transcription Machinery during the Transcription Cycle.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 2, p. 176, doi. 10.3390/biom14020176

By:

Archuleta, Stephen R.;
Goodrich, James A.;
Kugel, Jennifer F.

Publication type:

Article

PIP2-Effector Protein MPRIP Regulates RNA Polymerase II Condensation and Transcription.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 3, p. 426, doi. 10.3390/biom13030426

By:

Balaban, Can;
Sztacho, Martin;
Antiga, Ludovica;
Miladinović, Ana;
Harata, Masahiko;
Hozák, Pavel

Publication type:

Article

CAPTURE of the Human U2 snRNA Genes Expands the Repertoire of Associated Factors.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 5, p. 704, doi. 10.3390/biom12050704

By:

Guiro, Joana;
Fagbemi, Mathias;
Tellier, Michael;
Zaborowska, Justyna;
Barker, Stephanie;
Fournier, Marjorie;
Murphy, Shona

Publication type:

Article

Mechanisms of SOSS‐Integrator–PP2A complex in attenuating R‐loops and promoting genome stability.

Published in:

Clinical & Translational Medicine, 2024, v. 14, n. 1, p. 1, doi. 10.1002/ctm2.1519

By:

Wang, Jingwen;
Xu, Conglin;
Zhang, Zhen;
Chen, Fei Xavier

Publication type:

Article

The suppressive efficacy of THZ1 depends on KRAS mutation subtype and is associated with super‐enhancer activity and the PI3K/AKT/mTOR signalling in pancreatic ductal adenocarcinoma: A hypothesis‐generating study.

Published in:

Clinical & Translational Medicine, 2023, v. 13, n. 12, p. 1, doi. 10.1002/ctm2.1500

By:

Huang, Lei;
Yang, Hui;
Chen, Kaidi;
Yuan, Jing;
Li, Jie;
Dai, Guanghai;
Gu, Mancang;
Shi, Yan

Publication type:

Article

Editorial: Alternative Splicing Regulation in Plants.

Published in:

2020

By:

Petrillo, Ezequiel;
Kalyna, Maria;
Mandadi, Kranthi K.;
Tu, Shih-Long;
Simpson, Craig G.

Publication type:

Editorial

High Diversity of Cytospora Associated With Canker and Dieback of Rosaceae in China, With 10 New Species Described.

Published in:

Frontiers in Plant Science, 2020, v. 11, p. 1, doi. 10.3389/fpls.2020.00690

By:

Pan, Meng;
Zhu, Haiyan;
Bonthond, Guido;
Tian, Chengming;
Fan, Xinlei

Publication type:

Article

Arabidopsis SDG8 Potentiates the Sustainable Transcriptional Induction of the Pathogenesis-Related Genes PR1 and PR2 During Plant Defense Response.

Published in:

Frontiers in Plant Science, 2020, p. 1, doi. 10.3389/fpls.2020.00277

By:

Zhang, Xue;
Ménard, Rozenn;
Li, Ying;
Coruzzi, Gloria M.;
Heitz, Thierry;
Shen, Wen-Hui;
Berr, Alexandre

Publication type:

Article

BRF Negatively Regulates Thermotolerance Defect of fes1a in Arabidopsis.

Published in:

Frontiers in Plant Science, 2020, p. 1, doi. 10.3389/fpls.2020.00171

By:

Fu, Can;
Liu, Xiaxia;
Li, Xuezhi;
Huo, Panfei;
Ge, Jingjing;
Hou, Yanfei;
Yang, Wenwen;
Zhang, Jingxia;
Zhang, Limin;
Zhao, Dazhong;
Ma, Changle;
Liu, Jian

Publication type:

Article

The FACT Histone Chaperone: Tuning Gene Transcription in the Chromatin Context to Modulate Plant Growth and Development.

Published in:

Frontiers in Plant Science, 2020, p. 1, doi. 10.3389/fpls.2020.00085

By:

Grasser, Klaus D.

Publication type:

Article

Genetic Diversity in FUB Genes of Fusarium oxysporum f. sp. cubense Suggests Horizontal Gene Transfer.

Published in:

Frontiers in Plant Science, 2019, p. 1, doi. 10.3389/fpls.2019.01069

By:

Liu, Siwen;
Wu, Bo;
Lv, Shuxia;
Shen, Zongzhuan;
Li, Rong;
Yi, Ganjun;
Li, Chunyu;
Guo, Xiuwu

Publication type:

Article

Alternative Splicing and Transcription Elongation in Plants.

Published in:

Frontiers in Plant Science, 2019, p. N.PAG, doi. 10.3389/fpls.2019.00309

By:

Godoy Herz, Micaela A.;
Kornblihtt, Alberto R.

Publication type:

Article

Predictive value of DNA methylation in the efficacy of chemotherapy for gastric cancer.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1238310

By:

Ye Li;
Ning Mo;
Dong Yang;
QiuLu Lin;
WenFeng Huang;
Rensheng Wang

Publication type:

Article

Relationship between NUDT21 mediated alternative polyadenylation process and tumor.

Published in:

Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1052012

By:

Shan Xiao;
Huan Gu;
Li Deng;
Xiongtao Yang;
Dan Qiao;
Xudong Zhang;
Tian Zhang;
Tao Yu

Publication type:

Article

AATF/Che-1 RNA polymerase II binding protein overexpression reduces the anti-tumor NK-cell cytotoxicity through activating receptors modulation.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1191908

By:

Caforio, Matteo;
Tumino, Nicola;
Sorino, Cristina;
Manni, Isabella;
Di Giovenale, Stefano;
Piaggio, Giulia;
Iezzi, Simona;
Strimpakos, Georgios;
Mattei, Elisabetta;
Moretta, Lorenzo;
Fanciulli, M.;
Vacca, Paola;
Locatelli, Franco;
Folgiero, Valentina

Publication type:

Article

Topoisomerase 2β and DNA topology during B cell development.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 01, doi. 10.3389/fimmu.2022.982870

By:

Papapietro, Olivier;
Nejentsev, Sergey

Publication type:

Article

MED12 -Related Disease in a Chinese Girl: Clinical Characteristics and Underlying Mechanism.

Published in:

Frontiers in Genetics, 2020, p. 1, doi. 10.3389/fgene.2020.00129

By:

Wang, Chao;
Lin, Longlong;
Xue, Yan;
Wang, Yilin;
Liu, Zhao;
Ou, Zicheng;
Wu, Shengnan;
Lan, Xiaoping;
Zhang, Yuanfeng;
Yuan, Fang;
Luo, Xiaona;
Wang, Chunmei;
Xi, Jiaming;
Sun, Xiaomin;
Chen, Yucai

Publication type:

Article

Alveolar Macrophage Chromatin Is Modified to Orchestrate Host Response to Mycobacterium bovis Infection.

Published in:

Frontiers in Genetics, 2020, p. 1, doi. 10.3389/fgene.2019.01386

By:

Hall, Thomas J.;
Vernimmen, Douglas;
Browne, John A.;
Mullen, Michael P.;
Gordon, Stephen V.;
MacHugh, David E.;
O'Doherty, Alan M.

Publication type:

Article

Molecular and Phylogenetic Analyses of the Mediator Subunit Genes in Solanum lycopersicum.

Published in:

Frontiers in Genetics, 2019, v. 10, p. 1, doi. 10.3389/fgene.2019.01222

By:

Wang, Yunshu;
Liang, Honglian;
Chen, Guoping;
Liao, Changguang;
Wang, Yicong;
Hu, Zongli;
Xie, Qiaoli

Publication type:

Article

Enhancer LncRNAs Influence Chromatin Interactions in Different Ways.

Published in:

Frontiers in Genetics, 2019, p. 1, doi. 10.3389/fgene.2019.00936

By:

Hou, Yue;
Zhang, Rongxin;
Sun, Xiao

Publication type:

Article

Editorial: Current Advances in the Research of RNA Regulatory Enzymes.

Published in:

2019

By:

Kanai, Akio;
Yoshihisa, Tohru

Publication type:

Editorial

Long Noncoding RNA Can Be a Probable Mechanism and a Novel Target for Diagnosis and Therapy in Fragile X Syndrome.

Published in:

Frontiers in Genetics, 2019, p. N.PAG, doi. 10.3389/fgene.2019.00446

By:

Huang, Ge;
Zhu, He;
Wu, Shuying;
Cui, Manhua;
Xu, Tianmin

Publication type:

Article