Works matching AU Ruvkun, Gary

Results: 67

Identification of genes in toxicity pathways of trinucleotide-repeat RNA in C. elegans.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 8, p. 712, doi. 10.1038/nsmb.2858

By:

Garcia, Susana M D A;
Tabach, Yuval;
Lourenço, Guinevere F;
Armakola, Maria;
Ruvkun, Gary

Publication type:

Article

The exonuclease ERI-1 has a conserved dual role in 5.8S rRNA processing and RNAi.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 5, p. 531, doi. 10.1038/nsmb.1411

By:

Gabel, Harrison W.;
Ruvkun, Gary

Publication type:

Article

Pathogens.

Published in:

Virulence, 2014, v. 5, n. 7, p. 695, doi. 10.4161/viru.36667

By:

Govindan, J Amaranath;
Ruvkun, Gary

Publication type:

Article

The perfect storm of tiny RNAs.

Published in:

Nature Medicine, 2008, v. 14, n. 10, p. 1041, doi. 10.1038/nm1008-1041

By:

Ruvkun, Gary

Publication type:

Article

Polygenic control of Caenorhabditis elegans fat storage.

Published in:

Nature Genetics, 2006, v. 38, n. 3, p. 363, doi. 10.1038/ng1739

By:

Ho Yi Mak;
Nelson, Laura S.;
Basson, Michael;
Johnson, Carl D.;
Ruvkun, Gary

Publication type:

Article

MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression.

Published in:

Nature Genetics, 2004, v. 36, n. 10, p. 1079, doi. 10.1038/ng1421

By:

Mansfield, Jennifer H.;
Harfe, Brian D.;
Nissen, Robert;
Obenauer, John;
Srineel, Jalagani;
Chaudhuri, Aadel;
Farzan-Kashani, Raphael;
Zuker, Michael;
Pasquinelli, Amy E.;
Ruvkun, Gary;
Sharp, Phillip A.;
Tabin, Clifford J.;
McManus, Michael T.

Publication type:

Article

Breaking the silence.

Published in:

2004

By:

Ruvkun, Gary

Publication type:

Book Review

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity.

Published in:

Nature Genetics, 2003, v. 33, n. 1, p. 40, doi. 10.1038/ng1056

By:

Lee, Siu Sylvia;
Lee, Raymond Y.N.;
Fraser, Andrew G.;
Kamath, Ravi S.;
Ahringer, Julie;
Ruvkun, Gary

Publication type:

Article

Mitochondrial fission surveillance is coupled to Caenorhabditis elegans DNA and chromosome segregation integrity.

Published in:

PLoS Genetics, 2025, v. 21, n. 4, p. 1, doi. 10.1371/journal.pgen.1011678

By:

Yang, Xiaomeng;
Wei, Ruichen;
Meng, Fanfan;
Liu, Dianchen;
Gong, Xuan;
Ruvkun, Gary;
Wei, Wei

Publication type:

Article

The Most Conserved Genome Segments for Life Detection on Earth and Other Planets.

Published in:

Origins of Life & Evolution of the Biosphere, 2008, v. 38, n. 6, p. 517, doi. 10.1007/s11084-008-9148-z

By:

Isenbarger, Thomas;
Carr, Christopher;
Johnson, Sarah;
Finney, Michael;
Church, George;
Gilbert, Walter;
Zuber, Maria;
Ruvkun, Gary

Publication type:

Article

Acceleration profiles and processing methods for parabolic flight.

Published in:

NPJ Microgravity, 2018, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41526-018-0050-3

By:

Carr, Christopher E.;
Bryan, Noelle C.;
Saboda, Kendall N.;
Bhattaru, Srinivasa A.;
Ruvkun, Gary;
Zuber, Maria T.

Publication type:

Article

Dual Regulation of the <i>lin-14</i> Target mRNA by the <i>lin-4</i> miRNA.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075475

By:

Shi, Zhen;
Hayes, Gabriel;
Ruvkun, Gary

Publication type:

Article

Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0048282

By:

Tacutu, Robi;
Shore, David E.;
Budovsky, Arie;
de Magalhães, João Pedro;
Ruvkun, Gary;
Fraifeld, Vadim E.;
Curran, Sean P.

Publication type:

Article

Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling.

Published in:

Molecular Systems Biology, 2013, v. 9, n. 1, p. 1, doi. 10.1038/msb.2013.50

By:

Tabach, Yuval;
Golan, Tamar;
Hernández‐Hernández, Abrahan;
Messer, Arielle R;
Fukuda, Tomoyuki;
Kouznetsova, Anna;
Liu, Jian‐Guo;
Lilienthal, Ingrid;
Levy, Carmit;
Ruvkun, Gary

Publication type:

Article

Genomic and Functional Characterization of Enterococcus faecalis Isolates Recovered From the International Space Station and Their Potential for Pathogenicity.

Published in:

Frontiers in Microbiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.515319

By:

Bryan, Noelle C.;
Lebreton, Francois;
Gilmore, Michael;
Ruvkun, Gary;
Zuber, Maria T.;
Carr, Christopher E.

Publication type:

Article

Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of Caenorhabditis elegans.

Published in:

Genetics, 2018, v. 210, n. 4, p. 1329, doi. 10.1534/genetics.118.301450

By:

Tillman, Erik J.;
Richardson, Claire E.;
Cattie, Douglas J.;
Reddy, Kirthi C.;
Kim, Dennis H.;
Droste, Rita;
Lehrbach, Nicolas J.;
Ruvkun, Gary

Publication type:

Article

Recent Molecular Genetic Explorations of Caenorhabditis elegans MicroRNAs.

Published in:

Genetics, 2018, v. 209, n. 3, p. 651, doi. 10.1534/genetics.118.300291

By:

Ambros, Victor;
Ruvkun, Gary

Publication type:

Article

Gravity Force Transduced by the MEC-4/MEC-1O DEG/ENaC Channel Modulates DAF-16/FoxO Activity in Caenorhabditis elegans.

Published in:

Genetics, 2007, v. 177, n. 2, p. 835, doi. 10.1534/genetics.107.076901

By:

Nahui Kim;
Dempsey, Catherine M.;
Chih-Jen Kuan;
Zoval, Jim V.;
O'Rourke, Eyleen;
Ruvkun, Gary;
Madou, Marc J.;
Sze, Ji Y.

Publication type:

Article

A genetic interaction between the vesicular acetylcholine transporter VAChT/UNC-17 and synaptobrevin/SNB-1 in C. elegans.

Published in:

Nature Neuroscience, 2006, v. 9, n. 5, p. 599, doi. 10.1038/nn1685

By:

Sandoval, Gisela M.;
Duerr, Janet S.;
Hodgkin, Jonathan;
Rand, James B.;
Ruvkun, Gary

Publication type:

Article

DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity.

Published in:

Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-06624-0

By:

Lin, Xin-Xuan;
Sen, Ilke;
Janssens, Georges E.;
Zhou, Xin;
Fonslow, Bryan R.;
Edgar, Daniel;
Stroustrup, Nicholas;
Swoboda, Peter;
Yates, John R.;
Ruvkun, Gary;
Riedel, Christian G.

Publication type:

Article

Functional Genomic Analysis of C. elegans Molting.

Published in:

PLoS Biology, 2005, v. 3, n. 10, p. 1719, doi. 10.1371/journal.pbio.0030312

By:

Frand, Alison R.;
Russel, Sascha;
Ruvkun, Gary

Publication type:

Article

Functional Genomic Analysis of C. elegans Molting.

Published in:

PLoS Biology, 2005, v. 3, n. 8, p. 1, doi. 10.1371/journal.pbio.0030312

By:

Frand, Alison R;
Russel, Sascha;
Ruvkun, Gary

Publication type:

Article

MicroRNA-183 family conservation and ciliated neurosensory organ expression.

Published in:

Evolution & Development, 2008, v. 10, n. 1, p. 106, doi. 10.1111/j.1525-142X.2007.00217.x

By:

Pierce, Marsha L.;
Weston, Michael D.;
Fritzsch, Bernd;
Gabel, Harrison W.;
Ruvkun, Gary;
Soukup, Garrett A.

Publication type:

Article

Expression of the 22 nucleotide let-7 heterochronic RNA throughout the Metazoa: a role in life history evolution?

Published in:

Evolution & Development, 2003, v. 5, n. 4, p. 372, doi. 10.1046/j.1525-142X.2003.03044.x

By:

Pasquinelli, Amy E.;
McCoy, Adam;
Jiménez, Eva;
Saló, Emili;
Ruvkun, Gary;
Martindale, Mark Q.;
Baguñà, Jaume

Publication type:

Article

CarrierSeq: a sequence analysis workflow for low-input nanopore sequencing.

Published in:

BMC Bioinformatics, 2018, v. 19, p. 1, doi. 10.1186/s12859-018-2124-3

By:

Mojarro, Angel;
Hachey, Julie;
Ruvkun, Gary;
Zuber, Maria T.;
Carr, Christopher E.

Publication type:

Article

Biological safety in the context of backward planetary protection and Mars Sample Return: conclusions from the Sterilization Working Group.

Published in:

International Journal of Astrobiology, 2021, v. 20, n. 1, p. 1, doi. 10.1017/S1473550420000397

By:

Craven, Emily;
Winters, Martell;
Smith, Alvin L.;
Lalime, Erin;
Mancinelli, Rocco;
Shirey, Brian;
Schubert, Wayne;
Schuerger, Andrew;
Burgin, Mariko;
Seto, Emily P.;
Hendry, Morgan;
Mehta, Amruta;
Benardini, J. Nick;
Ruvkun, Gary

Publication type:

Article

An image analysis toolbox for high-throughput C. elegans assays.

Published in:

Nature Methods, 2012, v. 9, n. 7, p. 714, doi. 10.1038/nmeth.1984

By:

Wählby, Carolina;
Kamentsky, Lee;
Liu, Zihan H;
Riklin-Raviv, Tammy;
Conery, Annie L;
O'Rourke, Eyleen J;
Sokolnicki, Katherine L;
Visvikis, Orane;
Ljosa, Vebjorn;
Irazoqui, Javier E;
Golland, Polina;
Ruvkun, Gary;
Ausubel, Frederick M;
Carpenter, Anne E

Publication type:

Article

RNAi screening for fat regulatory genes with SRS microscopy.

Published in:

Nature Methods, 2011, v. 8, n. 2, p. 135, doi. 10.1038/nmeth.1556

By:

Wang, Meng C.;
Wei Min;
Freudiger, Christian W.;
Ruvkun, Gary;
Xie, X. Sunney

Publication type:

Article

Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response.

Published in:

PLoS Biology, 2020, v. 18, n. 12, p. 1, doi. 10.1371/journal.pbio.3000996

By:

Mao, Kai;
Breen, Peter;
Ruvkun, Gary

Publication type:

Article

A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.

Published in:

Nature, 2004, v. 427, n. 6975, p. 645, doi. 10.1038/nature02302

By:

Kennedy, Scott;
Duo Wang;
Ruvkun, Gary

Publication type:

Article

Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes.

Published in:

Nature, 2003, v. 421, n. 6920, p. 268, doi. 10.1038/nature01279

By:

Ashrafi, Kaveh;
Chang, Francesca Y.;
Watts, Jennifer L.;
Fraser, Andrew G.;
Kamath, Ravi S.;
Ahringer, Julie;
Ruvkun, Gary

Publication type:

Article

Don't hold your breath.

Published in:

Nature, 2002, v. 418, n. 6895, p. 287, doi. 10.1038/418287a

By:

Lee, Siu Sylvia;
Ruvkun, Gary

Publication type:

Article

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA.

Published in:

Nature, 2000, v. 408, n. 6808, p. 86, doi. 10.1038/35040556

By:

Pasquinelli, Amy E.;
Reinhart, Brenda J.;
Slack, Frank;
Martindale, Mark Q.;
Kuroda, Mitzi I.;
Maller, Betsy;
Hayward, David C.;
Ball, Eldon E.;
Degnan, Bernard;
Muller, Peter;
Spring, Jurg;
Srinivasan, Ashok;
Fishman, Mark;
Finnerty, John;
Corbo, Joseph;
Levine, Michael;
Leahy, Patrick;
Davidson, Eric;
Ruvkun, Gary

Publication type:

Article

Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant.

Published in:

Nature, 2000, v. 403, n. 6769, p. 560, doi. 10.1038/35000609

By:

Sze, Ji Ying;
Victor, Martin;
Loer, Curtis;
Shi, Yang;
Ruvkun, Gary

Publication type:

Article

DEPCOD: a tool to detect and visualize co-evolution of protein domains.

Published in:

Nucleic Acids Research, 2022, v. 50, n. W1, p. W246, doi. 10.1093/nar/gkac349

By:

Ji, Fei;
Bonilla, Gracia;
Krykbaev, Rustem;
Ruvkun, Gary;
Tabach, Yuval;
Sadreyev, Ruslan I

Publication type:

Article

Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 15, p. 8836, doi. 10.1093/nar/gkab619

By:

Charlesworth, Amanda G;
Seroussi, Uri;
Lehrbach, Nicolas J;
Renaud, Mathias S;
Sundby, Adam E;
Molnar, Ruxandra I;
Lao, Robert X;
Willis, Alexandra R;
Woock, Jenna R;
Aber, Matthew J;
Diao, Annette J;
Reinke, Aaron W;
Ruvkun, Gary;
Claycomb, Julie M

Publication type:

Article

Decreased SynMuv B gene activity in response to viral infection leads to activation of the antiviral RNAi pathway in C. elegans.

Published in:

PLoS Biology, 2025, v. 23, n. 1, p. 1, doi. 10.1371/journal.pbio.3002748

By:

Seetharaman, Ashwin;
Galagali, Himani;
Linarte, Elizabeth;
Liu, Mona H. X.;
Cohen, Jennifer D.;
Chetal, Kashish;
Sadreyev, Ruslan;
Tate, Alex J.;
Montgomery, Taiowa A.;
Ruvkun, Gary

Publication type:

Article

Mutations in nucleotide metabolism genes bypass proteasome defects in png-1/NGLY1-deficient Caenorhabditis elegans.

Published in:

PLoS Biology, 2024, v. 22, n. 7, p. 1, doi. 10.1371/journal.pbio.3002720

By:

Yanagi, Katherine S.;
Jochim, Briar;
Kunjo, Sheikh Omar;
Breen, Peter;
Ruvkun, Gary;
Lehrbach, Nicolas

Publication type:

Article

A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants.

Published in:

Nature, 2009, v. 459, n. 7250, p. 1079, doi. 10.1038/nature08106

By:

Curran, Sean P.;
Xiaoyun Wu;
Riedel, Christian G.;
Ruvkun, Gary

Publication type:

Article

Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7.

Published in:

Nature, 2008, v. 455, n. 7212, p. 491, doi. 10.1038/nature07274

By:

Fischer, Sylvia E. J.;
Butler, Maurice D.;
Qi Pan;
Ruvkun, Gary

Publication type:

Article

Systematic analysis of genes required for synapse structure and function.

Published in:

Nature, 2005, v. 436, n. 7050, p. 510, doi. 10.1038/nature03809

By:

Sieburth, Derek;
QueeLim Ch'ng;
Dybbs, Michael;
Tavazoie, Masoud;
Kennedy, Scott;
Duo Wang;
Dupuy, Denis;
Rual, Jean-François;
Hill, David E.;
Vidal, Marc;
Ruvkun, Gary;
Kaplan, Joshua M.

Publication type:

Article

Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants.

Published in:

Nature, 2005, v. 436, n. 7050, p. 593, doi. 10.1038/nature04010

By:

Duo Wang;
Kennedy, Scott;
Conte Jr., Darryl;
Kim, John K.;
Gabel, Harrison W.;
Kamath, Ravi S.;
Mello, Craig C.;
Ruvkun, Gary

Publication type:

Article

Isoform-Specific Mutations in the Caenorhabditis elegans Heterochronic Gene lin-14 Affect...

Published in:

Genetics, 2001, v. 157, n. 1, p. 199, doi. 10.1093/genetics/157.1.199

By:

Reinhart, Brenda J.;
Ruvkun, Gary

Publication type:

Article

An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans.

Published in:

Genetics, 1998, v. 148, n. 2, p. 703, doi. 10.1093/genetics/148.2.703

By:

Tissenbaum, Heidi A.;
Ruvkun, Gary

Publication type:

Article

Daf-2, daf-16 and daf-23: Genetically interacting genes controlling Dauer formation in...

Published in:

Genetics, 1994, v. 137, n. 1, p. 107, doi. 10.1093/genetics/137.1.107

By:

Gottlieb, Shoshanna;
Ruvkun, Gary

Publication type:

Article

Molecular Genetics of the Caenorhabditis elegans Heterochronic Gene lin-14.

Published in:

Genetics, 1989, v. 121, n. 3, p. 501

By:

Ruvkun, Gary;
Ambros, Victor;
Coulson, Alan;
Waterston, Robert;
Sulston, John;
Horvitz, H. Robert

Publication type:

Article

Microbial Diversity in a Hypersaline Sulfate Lake: A Terrestrial Analog of Ancient Mars.

Published in:

Frontiers in Microbiology, 2017, p. 1, doi. 10.3389/fmicb.2017.01819

By:

Pontefract, Alexandra;
Zhu, Ting F.;
Walker, Virginia K.;
Hepburn, Holli;
Lui, Clarissa;
Zuber, Maria T.;
Ruvkun, Gary;
Carr, Christopher E.

Publication type:

Article

A general method for site-directed mutagenesis in prokaryotes.

Published in:

Nature, 1981, v. 289, n. 5793, p. 85, doi. 10.1038/289085a0

By:

Ruvkun, Gary B.;
Ausubel, Frederick M.

Publication type:

Article

Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.89173

By:

Warnhoff, Kurt;
Bhattacharya, Sushila;
Snoozy, Jennifer;
Breen, Peter C.;
Ruvkun, Gary

Publication type:

Article

Graded expression of ceh-14 reporters in the hypodermis is induced by a gonadal signal.

Published in:

Development Genes & Evolution, 2000, v. 210, n. 11, p. 564, doi. 10.1007/s004270000099

By:

Kagoshima, Hiroshi;
Sommer, Ralf;
Reinhart, Brenda J.;
Cassata, Giuseppe;
Ruvkun, Gary;
Bürglin, T. R.

Publication type:

Article