Works matching IS 15250016 AND DT 2010 AND VI 18

Results: 309

Laminin-111: A Potential Therapeutic Agent for Duchenne Muscular Dystrophy.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2155, doi. 10.1038/mt.2010.165

By:

Goudenege, Sébastien;
Lamarre, Yann;
Dumont, Nicolas;
Rousseau, Joël;
Frenette, Jérôme;
Skuk, Daniel;
Tremblay, Jacques P.

Publication type:

Article

A Short Pulse of IL-4 Delivered by DCs Electroporated With Modified mRNA Can Both Prevent and Treat Autoimmune Diabetes in NOD Mice.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2112, doi. 10.1038/mt.2010.146

By:

Creusot, Rémi J.;
Chang, Pearl;
Healey, Don G.;
Tcherepanova, Irina Y.;
Nicolette, Charles A.;
Fathman, C. Garrison

Publication type:

Article

Induction of Immune Tolerance to a Therapeutic Protein by Intrathymic Gene Delivery.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2146, doi. 10.1038/mt.2010.164

By:

Qiuming Chu;
Moreland, Rodney J.;
Lan Gao;
Taylor, Kristin M.;
Meyers, Elizabeth;
Cheng, Seng H.;
Scheule, Ronald K.

Publication type:

Article

Lentivirus-mediated Reprogramming of Somatic Cells in the Absence of Transgenic Transcription Factors.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2139, doi. 10.1038/mt.2010.231

By:

Kane, Nicole M.;
Nowrouzi, Ali;
Mukherjee, Sayandip;
Blundell, Michael P.;
Greig, Jenny A.;
Wai Kwong Lee;
Houslay, Miles D.;
Milligan, Graeme;
Mountford, Joanne C.;
von Kalle, Christof;
Schmidt, Manfred;
Thrasher, Adrian J.;
Baker, Andrew H.

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2010, v. 18, n. 12, p. 2040, doi. 10.1038/mt.2010.252
Publication type:: Article

Expansive Gene Transfer in the Rat CNS Rapidly Produces Amyotrophic Lateral Sclerosis Relevant Sequelae When TDP-43 is Overexpressed.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2064, doi. 10.1038/mt.2010.191

By:

Wang, David B.;
Dayton, Robert D.;
Henning, Phillip P.;
Cain, Cooper D.;
Li Ru Zhao;
Schrott, Lisa M.;
Orchard, Elysse A.;
Knight, David S.;
Klein, Ronald L.

Publication type:

Article

The Stem Cell 'Tunnel' Effect.

Published in:

2010

By:

Zwaka, Thomas P.

Publication type:

Opinion

The Effect of Cell Cycle Synchronization on Tumor Sensitivity to Reovirus Oncolysis.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2085, doi. 10.1038/mt.2010.189

By:

Heinemann, Lucy;
Simpson, Guy R.;
Annels, Nicola E.;
Vile, Richard;
Melcher, Alan;
Prestwich, Robin;
Harrington, Kevin J.;
Pandha, Hardev S.

Publication type:

Article

Retraction to'Metabolic Basis of Sexual Dimorphism in PKU Mice After Genome-targeted PAH Gene Therapy'.

Published in:: 2010
Publication type:: Correction Notice

Gene Delivery of a Mutant TGFβ3 Reduces Markers of Scar Tissue Formation After Cutaneous Wounding.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2104, doi. 10.1038/mt.2010.174

By:

Waddington, Simon N.;
Crossley, Rachel;
Sheard, Vicky;
Howe, Steven J.;
Buckley, Suzanne M. K.;
Coughlan, Lynda;
Gilham, David E.;
Hawkins, Robert E.;
McKay, Tristan R.

Publication type:

Article

AAV4-mediated Expression of IGF-1 and VEGF Within Cellular Components of the Ventricular System Improves Survival Outcome in Familial ALS Mice.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2075, doi. 10.1038/mt.2010.206

By:

Dodge, James C.;
Treleaven, Christopher M.;
Fidler, Jonathan A.;
Hester, Mark;
Haidet, Amanda;
Handy, Chalonda;
Meghan Rao;
Eagle, Amy;
Matthews, Jennifer C.;
Taksir, Tatyana V.;
Cheng, Seng H.;
Shihabuddin, Lamya S.;
Kaspar, Brian K.

Publication type:

Article

VSV Oncolysis in Combination With the BCL-2 Inhibitor Obatoclax Overcomes Apoptosis Resistance in Chronic Lymphocytic Leukemia.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2094, doi. 10.1038/mt.2010.188

By:

Samuel, Sara;
Tumilasci, Vanessa F.;
Oliere, Stephanie;
Thi Liên-Anh Nguyên;
Shamy, April;
Bell, John;
Hiscott, John

Publication type:

Article

Restoration of Cone Vision in the CNGA3<sup>−/−</sup> Mouse Model of Congenital Complete Lack of Cone Photoreceptor Function.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2057, doi. 10.1038/mt.2010.149

By:

Michalakis, Stylianos;
Mühlfriedel, Regine;
Tanimoto, Naoyuki;
Krishnamoorthy, Vidhyasankar;
Koch, Susanne;
Fischer, M. Dominik;
Becirovic, Elvir;
Lin Bai;
Huber, Gesine;
Beck, Susanne C.;
Fahl, Edda;
Büning, Hildegard;
Paquet-Durand, François;
Xiangang Zong;
Gollisch, Tim;
Biel, Martin;
Seeliger, Mathias W.

Publication type:

Article

Autoimmunity, Recessive Diseases, and Gene Replacement Therapy.

Published in:

2010

By:

Wilson, James M.

Publication type:

Opinion

Nodal/Activin Signaling Predicts Human Pluripotent Stem Cell Lines Prone to Differentiate Toward the Hematopoietic Lineage.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2173, doi. 10.1038/mt.2010.179

By:

Ramos-Mejia, Veronica;
Melen, Gustavo J.;
Sanchez, Laura;
Gutierrez-Aranda, Ivan;
Ligero, Gertrudis;
Cortes, Jose L.;
Real, Pedro J.;
Bueno, Clara;
Menendez, Pablo

Publication type:

Article

The Need for Genetically Engineering Therapeutic Pluripotent Stem Cells.

Published in:

2010

By:

Sadelain, Michel

Publication type:

Editorial

Research Highlights.

Published in:: Molecular Therapy, 2010, v. 18, n. 12, p. 2041, doi. 10.1038/mt.2010.251
Publication type:: Article

High-efficiency Transduction and Correction of Murine Hemophilia B Using AAV2 Vectors Devoid of Multiple Surface-exposed Tyrosines.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2048, doi. 10.1038/mt.2010.172

By:

Markusic, David M.;
Herzog, Roland W.;
Aslanidi, George V.;
Hoffman, Brad E.;
Baozheng Li;
Mengxin Li;
Jayandharan, Giridhara R.;
Chen Ling;
Zolotukhin, Irene;
Wenqin Ma;
Zolotukhin, Sergei;
Srivastava, Arun;
Li Zhong

Publication type:

Article

Retraction to 'Correction in Female PKU Mice by Repeated Administration of mPAH cDNA Using phiBT1 Integration System'.

Published in:: 2010
Publication type:: Correction Notice

Helper-dependent Adenoviral Vectors are Superior In Vitro to First-generation Vectors for Endothelial Cell-targeted Gene Therapy.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2121, doi. 10.1038/mt.2010.176

By:

Flynn, Rowan;
Buckler, Joshua M.;
Chongren Tang;
Kim, Francis;
Dichek, David A.

Publication type:

Article

A Universal Influenza A Vaccine Based on Adenovirus Expressing Matrix-2 Ectodomain and Nucleoprotein Protects Mice From Lethal Challenge.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2182, doi. 10.1038/mt.2010.202

By:

Dongming Zhou;
Te-Lang Wu;
Lasaro, Marcio O.;
Latimer, Brian P.;
Parzych, Elizabeth M.;
Ang Bian;
Yan Li;
Hua Li;
Erikson, Jan;
Zhiquan Xiang;
Ertl, Hildegund C. J.

Publication type:

Article

Efficient Gene Transfer Into the Mouse Lung by Fetal Intratracheal Injection of rAAV2/6.2.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2130, doi. 10.1038/mt.2010.153

By:

Carlon, Marianne;
Toelen, Jaan;
Van der Perren, Anke;
Vandenberghe, Luk H.;
Reumers, Veerle;
Sbragia, Lourenço;
Gijsbers, Rik;
Baekelandt, Veerle;
Himmelreich, Uwe;
Wilson, James M;
Deprest, Jan;
Debyser, Zeger

Publication type:

Article

Liver Regeneration From Induced Pluripotent Stem Cells.

Published in:

2010

By:

Xin Cheng;
Gadue, Paul

Publication type:

Opinion

Long-term Delivery of Nerve Growth Factor by Encapsulated Cell Biodelivery in the Göttingen Minipig Basal Forebrain.

Published in:

Molecular Therapy, 2010, v. 18, n. 12, p. 2164, doi. 10.1038/mt.2010.154

By:

Fjord-Larsen, Lone;
Kusk, Philip;
Tornøe, Jens;
Juliusson, Bengt;
Torp, Malene;
Bjarkam, Carsten R.;
Nielsen, Mette S.;
Handberg, Aase;
Sørensen, Jens Christian H.;
Wahlberg, Lars U.

Publication type:

Article

Gene Therapy for SCID-X1: Round 2.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 1891, doi. 10.1038/mt.2010.228

By:

Herzog, Roland W.

Publication type:

Article

Chemotherapy Delivered After Viral Immunogene Therapy Augments Antitumor Efficacy Via Multiple Immune-mediated Mechanisms.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 1947, doi. 10.1038/mt.2010.159

By:

Fridlender, Zvi G.;
Jing Sun;
Singhal, Sunil;
Kapoor, Veena;
Guanjun Cheng;
Suzuki, Eiji;
Albelda, Steven M.

Publication type:

Article

Efficacy and Safety/Toxicity Study of Recombinant Vaccinia Virus JX-594 in Two Immunocompetent Animal Models of Glioma.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 1927, doi. 10.1038/mt.2010.183

By:

XueQing Lun;
Chan, Jennifer;
Hongyuan Zhou;
Beichen Sun;
Kelly, John J. P.;
Stechishin, Owen Owen;
Bell, John C.;
Parato, Kelley;
Kang Hu;
Vaillant, Dominique;
Jiahu Wang;
Ta-Chiang Liu;
Breitbach, Caroline;
Kirn, David;
Senger, Donna L.;
Forsyth, Peter A.

Publication type:

Article

siRNA Nanoparticle Functionalization of Nanostructured Scaffolds Enables Controlled Multilineage Differentiation of Stem Cells.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 2018, doi. 10.1038/mt.2010.166

By:

Andersen, Morten Ø.;
Nygaard, Jens V.;
Burns, Jorge S.;
Raarup, Merete K.;
Nyengaard, Jens R.;
Bünger, Cody;
Besenbacher, Flemming;
Howard, Kenneth A.;
Kassem, Moustapha;
Kjems, Jørgen

Publication type:

Article

Minimal RB-responsive E1A Promoter Modification to Attain Potency, Selectivity, and Transgene-arming Capacity in Oncolytic Adenoviruses.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 1960, doi. 10.1038/mt.2010.173

By:

Rojas, Juan J.;
Guedan, Sonia;
Searle, Peter F.;
Martinez-Quintanilla, Jordi;
Gil-Hoyos, Raúl;
Alcayaga-Miranda, Francisca;
Cascallo, Manel;
Alemany, Ramon

Publication type:

Article

Research Highlights.

Published in:: Molecular Therapy, 2010, v. 18, n. 11, p. 1895, doi. 10.1038/mt.2010.220
Publication type:: Article

Transatlantic Consortium Spotlights Need for Changes in Gene Therapy Trials.

Published in:

2010

By:

Williams, David A.;
Thrasher, Adrian J.;
Baum, Christopher

Publication type:

Editorial

Enhanced Induction of HIV-specific Cytotoxic T Lymphocytes by Dendritic Cell-targeted Delivery of SOCS-1 siRNA.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 2028, doi. 10.1038/mt.2010.148

By:

Subramanya, Sandesh;
Armant, Myriam;
Salkowitz, Janelle R.;
Nyakeriga, Alice M.;
Haridas, Viraga;
Hasan, Maroof;
Bansal, Anju;
Goepfert, Paul A.;
Wynn, Katherine K.;
Ladell, Kristin;
Price, David A.;
N., Manjunath;
Kan-Mitchell, June;
Shankar, Premlata

Publication type:

Article

Proteasome Inhibitors Enhance Gene Delivery by AAV Virus Vectors Expressing Large Genomes in Hemophilia Mouse and Dog Models: A Strategy for Broad Clinical Application.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 1907, doi. 10.1038/mt.2010.170

By:

Monahan, Paul E.;
Lothrop, Clinton D.;
Junjiang Sun;
Hirsch, Matthew L.;
Kafri, Tal;
Kantor, Boris;
Sarkar, Rita;
Tillson, D. Michael;
Elia, Joseph R.;
Samulski, R. Jude

Publication type:

Article

Hyperactive Sleeping Beauty Transposase Enables Persistent Phenotypic Correction in Mice and a Canine Model for Hemophilia B.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 1896, doi. 10.1038/mt.2010.169

By:

Hausl, Martin A.;
Wenli Zhang;
Müther, Nadine;
Rauschhuber, Christina;
Franck, Helen G.;
Merricks, Elizabeth P.;
Nichols, Timothy C.;
Kay, Mark A.;
Ehrhardt, Anja

Publication type:

Article

POD Nanoparticles Expressing GDNF Provide Structural and Functional Rescue of Light-induced Retinal Degeneration in an Adult Mouse.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 1917, doi. 10.1038/mt.2010.167

By:

Read, Sarah P.;
Cashman, Siobhan M.;
Kumar-Singh, Rajendra

Publication type:

Article

MAPK Signal-integrating Kinase Controls Cap-independent Translation and Cell Type-specific Cytotoxicity of an Oncolytic Poliovirus.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 1937, doi. 10.1038/mt.2010.145

By:

Goetz, Christian;
Everson, Richard G.;
Zhang, Linda C.;
Gromeier, Matthias

Publication type:

Article

T Cells Expressing Constitutively Active Akt Resist Multiple Tumor-associated Inhibitory Mechanisms.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 2006, doi. 10.1038/mt.2010.185

By:

Sun, Jiali;
Dotti, Gianpietro;
Huye, Leslie E.;
Foster, Aaron E.;
Savoldo, Barbara;
Gramatges, Maria M.;
Spencer, David M.;
Rooney, Cliona M.

Publication type:

Article

Corrigendum to 'Gene Transfer Efficiency and Genome-Wide Integration Profiling of Sleeping Beauty, Tol2, and PiggyBac Transposons in Human Primary T Cells'.

Published in:: 2010
Publication type:: Correction Notice

In-frame Dystrophin Following Exon 51-Skipping Improves Muscle Pathology and Function in the Exon 52-Deficient mdx Mouse.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 1995, doi. 10.1038/mt.2010.186

By:

Aoki, Yoshitsugu;
Nakamura, Akinori;
Yokota, Toshifumi;
Saito, Takashi;
Okazawa, Hitoshi;
Nagata, Tetsuya;
Takeda, Shin'ichi

Publication type:

Article

Preexisting Immunity and Low Expression in Primates Highlight Translational Challenges for Liver-directed AAV8-mediated Gene Therapy.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 1983, doi. 10.1038/mt.2010.175

By:

Hurlbut, Gregory D.;
Ziegler, Robin J.;
Nietupski, Jennifer B.;
Foley, Joseph W.;
Woodworth, Lisa A.;
Meyers, Elizabeth;
Bercury, Scott D.;
Pande, Nilesh N.;
Souza, David W.;
Bree, Mark P.;
Lukason, Michael J.;
Marshall, John;
Cheng, Seng H.;
Scheule, Ronald K.

Publication type:

Article

Selectivity of Oncolytic Viral Replication Prevents Antiviral Immune Response and Toxicity, but Does Not Improve Antitumoral Immunity.

Published in:

Molecular Therapy, 2010, v. 18, n. 11, p. 1972, doi. 10.1038/mt.2010.163

By:

Gürlevik, Engin;
Woller, Norman;
Strüver, Nina;
Schache, Peter;
Kloos, Arnold;
Manns, Michael P.;
Zender, Lars;
Kühnel, Florian;
Kubicka, Stefan

Publication type:

Article

In This Issue.

Published in:: 2010
Publication type:: Abstract

α-Synuclein Expression in Rat Substantia Nigra Suppresses Phospholipase D2 Toxicity and Nigral Neurodegeneration.

Published in:

Molecular Therapy, 2010, v. 18, n. 10, p. 1758, doi. 10.1038/mt.2010.137

By:

Gorbatyuk, Oleg S.;
Shoudong Li;
Nha Nguyen, Frederic;
Manfredsson, Fredric P.;
Kondrikova, Galina;
Sullivan, Layla F.;
Meyers, Craig;
Weijun Chen;
Mandel, Ronald J.;
Muzyczka, Nicholas

Publication type:

Article

Prophylactic Antiparasitic Transgenesis for Human Parasitic Disease?

Published in:

Molecular Therapy, 2010, v. 18, n. 10, p. 1745, doi. 10.1038/mt.2010.193

By:

Lukeš, Julius;
Raper, Jayne

Publication type:

Article

Functional Rescue of Dystrophin-deficient mdx Mice by a Chimeric Peptide-PMO.

Published in:

Molecular Therapy, 2010, v. 18, n. 10, p. 1822, doi. 10.1038/mt.2010.151

By:

HaiFang Yin;
Moulton, Hong M.;
Betts, Corinne;
Merritt, Thomas;
Seow, Yiqi;
Ashraf, Shirin;
QingSong Wang;
Boutilier, Jordan;
Wood, Matthew J. A.

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2010, v. 18, n. 10, p. 1740, doi. 10.1038/mt.2010.196
Publication type:: Article

Advances in the Field of Lentivector-based Transduction of T and B Lymphocytes for Gene Therapy.

Published in:

Molecular Therapy, 2010, v. 18, n. 10, p. 1748, doi. 10.1038/mt.2010.178

By:

Frecha, Cecilia;
Lévy, Camille;
Cosset, François-Loïc;
Verhoeyen, Els

Publication type:

Article

Duration of Expression and Activity of Sleeping Beauty Transposase in mouse liver following hydrodynamic DNA delivery.

Published in:

Molecular Therapy, 2010, v. 18, n. 10, p. 1796, doi. 10.1038/mt.2010.152

By:

Bell, Jason B.;
Aronovich, Elena L.;
Schreifels, Jeffrey M.;
Beadnell, Thomas C.;
Hackett, Perry B.

Publication type:

Article

Is It Safer CARs That We Need, or Safer Rules of the Road?

Published in:

2010

By:

Junghans, Richard P.

Publication type:

Letter

Bone Marrow Mesenchymal Stem Cells Loaded With an Oncolytic Adenovirus Suppress the Anti-adenoviral Immune Response in the Cotton Rat Model.

Published in:

Molecular Therapy, 2010, v. 18, n. 10, p. 1846, doi. 10.1038/mt.2010.131

By:

Ahmed, Atique U.;
Rolle, Cleo E.;
Tyler, Matthew A.;
Yu Han;
Sengupta, Sadhak;
Wainwright, Derek A.;
Balyasnikova, Irina V.;
Ulasov, Ilya V.;
Lesniak, Maciej S.

Publication type:

Article