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Involvement of double-stranded RNA-dependent protein kinase and antisense viral RNA in the constitutive NF[kappa]B activation in adult T-cell leukemia/lymphoma cells.
Published in:
2015
By:
- Kinpara, S;
- Ito, S;
- Takahata, T;
- Saitoh, Y;
- Hasegawa, A;
- Kijiyama, M;
- Utsunomiya, A;
- Masuda, M;
- Miyazaki, Y;
- Matsuoka, M;
- Nakamura, M;
- Yamaoka, S;
- Masuda, T;
- Kannagi, M
Publication type:
Journal Article
HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α.
Published in:
2015
By:
- Forristal, C E;
- Nowlan, B;
- Jacobsen, R N;
- Barbier, V;
- Walkinshaw, G;
- Walkley, C R;
- Winkler, I G;
- Levesque, J P
Publication type:
journal article
Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells.
Published in:
2015
By:
- Fiskus, W;
- Sharma, S;
- Saha, S;
- Shah, B;
- Devaraj, S G T;
- Sun, B;
- Horrigan, S;
- Leveque, C;
- Zu, Y;
- Iyer, S;
- Bhalla, K N
Publication type:
journal article
Colony-stimulating factor-3 receptor, watch out for polymorphisms.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1445, doi. 10.1038/leu.2015.25
By:
- Bilbao-Sieyro, C;
- Santana, G;
- Torres-Miñana, L;
- Rodriguez-Medina, C;
- Saez, M N;
- Perera, M;
- Lemes, Angelina;
- de la Iglesia, S;
- Molero, T;
- Gomez-Casares, M T
Publication type:
Article
Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1301, doi. 10.1038/leu.2015.27
By:
- Witkowski, M T;
- Cimmino, L;
- Hu, Y;
- Trimarchi, T;
- Tagoh, H;
- McKenzie, M D;
- Best, S A;
- Tuohey, L;
- Willson, T A;
- Nutt, S L;
- Busslinger, M;
- Aifantis, I;
- Smyth, G K;
- Dickins, R A
Publication type:
Article
A randomised comparison of the novel nucleoside analogue sapacitabine with low-dose cytarabine in older patients with acute myeloid leukaemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1312, doi. 10.1038/leu.2015.38
By:
- Burnett, A K;
- Russell, N;
- Hills, R K;
- Panoskaltsis, N;
- Khwaja, A;
- Hemmaway, C;
- Cahalin, P;
- Clark, R E;
- Milligan, D
Publication type:
Article
Involvement of double-stranded RNA-dependent protein kinase and antisense viral RNA in the constitutive NFκB activation in adult T-cell leukemia/lymphoma cells.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1425, doi. 10.1038/leu.2015.1
By:
- Kinpara, S;
- Ito, S;
- Takahata, T;
- Saitoh, Y;
- Hasegawa, A;
- Kijiyama, M;
- Utsunomiya, A;
- Masuda, M;
- Miyazaki, Y;
- Matsuoka, M;
- Nakamura, M;
- Yamaoka, S;
- Masuda, T;
- Kannagi, M
Publication type:
Article
Mutations and long-term outcome of 217 young patients with essential thrombocythemia or early primary myelofibrosis.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1344, doi. 10.1038/leu.2015.87
By:
- Palandri, F;
- Latagliata, R;
- Polverelli, N;
- Tieghi, A;
- Crugnola, M;
- Martino, B;
- Perricone, M;
- Breccia, M;
- Ottaviani, E;
- Testoni, N;
- Merli, F;
- Aversa, F;
- Alimena, G;
- Cavo, M;
- Martinelli, G;
- Catani, L;
- Baccarani, M;
- Vianelli, N
Publication type:
Article
Interferon alpha 2 maintenance therapy may enable high rates of treatment discontinuation in chronic myeloid leukemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1331, doi. 10.1038/leu.2015.45
By:
- Burchert, A;
- Saussele, S;
- Eigendorff, E;
- Müller, M C;
- Sohlbach, K;
- Inselmann, S;
- Schütz, C;
- Metzelder, S K;
- Ziermann, J;
- Kostrewa, P;
- Hoffmann, J;
- Hehlmann, R;
- Neubauer, A;
- Hochhaus, A
Publication type:
Article
Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1279, doi. 10.1038/leu.2015.6
By:
- Spencer, D H;
- Young, M A;
- Lamprecht, T L;
- Helton, N M;
- Fulton, R;
- O'Laughlin, M;
- Fronick, C;
- Magrini, V;
- Demeter, R T;
- Miller, C A;
- Klco, J M;
- Wilson, R K;
- Ley, T J
Publication type:
Article
CDK9 inhibition by dinaciclib potently suppresses Mcl-1 to induce durable apoptotic responses in aggressive MYC-driven B-cell lymphoma in vivo.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1437, doi. 10.1038/leu.2015.10
By:
- Gregory, G P;
- Hogg, S J;
- Kats, L M;
- Vidacs, E;
- Baker, A J;
- Gilan, O;
- Lefebure, M;
- Martin, B P;
- Dawson, M A;
- Johnstone, R W;
- Shortt, J
Publication type:
Article
L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1253, doi. 10.1038/leu.2014.338
By:
- Rosilio, C;
- Nebout, M;
- Imbert, V;
- Griessinger, E;
- Neffati, Z;
- Benadiba, J;
- Hagenbeek, T;
- Spits, H;
- Reverso, J;
- Ambrosetti, D;
- Michiels, J-F;
- Bailly-Maitre, B;
- Endou, H;
- Wempe, M F;
- Peyron, J-F
Publication type:
Article
Diagnostic and prognostic role of PET/CT in patients with chronic lymphocytic leukemia and progressive disease.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1360, doi. 10.1038/leu.2015.21
By:
- Mauro, F R;
- Chauvie, S;
- Paoloni, F;
- Biggi, A;
- Cimino, G;
- Rago, A;
- Gentile, M;
- Morabito, F;
- Coscia, M;
- Bellò, M;
- Sacchetti, G M;
- Rossi, D;
- Laurenti, L;
- Autore, F;
- Campanelli, M;
- Trastulli, F;
- Nicolai, E;
- Riminucci, M;
- Gaidano, G;
- Guarini, A
Publication type:
Article
Early B-cell-specific inactivation of ATM synergizes with ectopic CyclinD1 expression to promote pre-germinal center B-cell lymphomas in mice.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1414, doi. 10.1038/leu.2015.41
By:
- Yamamoto, K;
- Lee, B J;
- Li, C;
- Dubois, R L;
- Hobeika, E;
- Bhagat, G;
- Zha, S
Publication type:
Article
Role of chromosomal aberrations in clonal diversity and progression of acute myeloid leukemia.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1243, doi. 10.1038/leu.2015.32
By:
- Bochtler, T;
- Fröhling, S;
- Krämer, A
Publication type:
Article
Targeting PD1-PDL1 immune checkpoint in plasmacytoid dendritic cell interactions with T cells, natural killer cells and multiple myeloma cells.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1441, doi. 10.1038/leu.2015.11
By:
- Ray, A;
- Das, D S;
- Song, Y;
- Richardson, P;
- Munshi, N C;
- Chauhan, D;
- Anderson, K C
Publication type:
Article
Allelic imbalance in CALR somatic mutagenesis.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1431, doi. 10.1038/leu.2015.3
By:
- Harutyunyan, A S;
- Jäger, R;
- Chen, D;
- Berg, T;
- Rumi, E;
- Gisslinger, B;
- Pietra, D;
- Gisslinger, H;
- Cazzola, M;
- Kralovics, R
Publication type:
Article
KIT mutation analysis in mast cell neoplasms: recommendations of the European Competence Network on Mastocytosis.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1223, doi. 10.1038/leu.2015.24
By:
- Arock, M;
- Sotlar, K;
- Akin, C;
- Broesby-Olsen, S;
- Hoermann, G;
- Escribano, L;
- Kristensen, T K;
- Kluin-Nelemans, H C;
- Hermine, O;
- Dubreuil, P;
- Sperr, W R;
- Hartmann, K;
- Gotlib, J;
- Cross, N C P;
- Haferlach, T;
- Garcia-Montero, A;
- Orfao, A;
- Schwaab, J;
- Triggiani, M;
- Horny, H-P
Publication type:
Article
Replication factor C3 is a CREB target gene that regulates cell cycle progression through the modulation of chromatin loading of PCNA.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1379, doi. 10.1038/leu.2014.350
By:
- Chae, H-D;
- Mitton, B;
- Lacayo, N J;
- Sakamoto, K M
Publication type:
Article
A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1390, doi. 10.1038/leu.2014.347
By:
- Abate, F;
- Todaro, M;
- van der Krogt, J-A;
- Boi, M;
- Landra, I;
- Machiorlatti, R;
- Tabbò, F;
- Messana, K;
- Abele, C;
- Barreca, A;
- Novero, D;
- Gaudiano, M;
- Aliberti, S;
- Di Giacomo, F;
- Tousseyn, T;
- Lasorsa, E;
- Crescenzo, R;
- Bessone, L;
- Ficarra, E;
- Acquaviva, A
Publication type:
Article
Imprinted genes in myeloid lineage commitment in normal and malignant hematopoiesis.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1233, doi. 10.1038/leu.2015.47
By:
- Benetatos, L;
- Vartholomatos, G
Publication type:
Article
Mutated Ptpn11 alters leukemic stem cell frequency and reduces the sensitivity of acute myeloid leukemia cells to Mcl1 inhibition.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1290, doi. 10.1038/leu.2015.18
By:
- Chen, L;
- Chen, W;
- Mysliwski, M;
- Serio, J;
- Ropa, J;
- Abulwerdi, F A;
- Chan, R J;
- Patel, J P;
- Tallman, M S;
- Paietta, E;
- Melnick, A;
- Levine, R L;
- Abdel-Wahab, O;
- Nikolovska-Coleska, Z;
- Muntean, A G
Publication type:
Article
Elevated serum sCD23 and sCD30 up to two decades prior to diagnosis associated with increased risk of non-Hodgkin lymphoma.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1429, doi. 10.1038/leu.2015.2
By:
- Purdue, M P;
- Lan, Q;
- Kemp, T J;
- Hildesheim, A;
- Weinstein, S J;
- Hofmann, J N;
- Virtamo, J;
- Albanes, D;
- Pinto, L A;
- Rothman, N
Publication type:
Article
The role of Lin28b in myeloid and mast cell differentiation and mast cell malignancy.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1320, doi. 10.1038/leu.2015.19
By:
- Wang, L D;
- Rao, T N;
- Rowe, R G;
- Nguyen, P T;
- Sullivan, J L;
- Pearson, D S;
- Doulatov, S;
- Wu, L;
- Lindsley, R C;
- Zhu, H;
- DeAngelo, D J;
- Daley, G Q;
- Wagers, A J
Publication type:
Article
The EUTOS population-based registry: incidence and clinical characteristics of 2904 CML patients in 20 European Countries.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1336, doi. 10.1038/leu.2015.73
By:
- Hoffmann, V S;
- Baccarani, M;
- Hasford, J;
- Lindoerfer, D;
- Burgstaller, S;
- Sertic, D;
- Costeas, P;
- Mayer, J;
- Indrak, K;
- Everaus, H;
- Koskenvesa, P;
- Guilhot, J;
- Schubert-Fritschle, G;
- Castagnetti, F;
- Di Raimondo, F;
- Lejniece, S;
- Griskevicius, L;
- Thielen, N;
- Sacha, T;
- Hellmann, A
Publication type:
Article
BIN1 tumor suppressor regulates Fas/Fas ligand-mediated apoptosis through c-FLIP in cutaneous T-cell lymphoma.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1402, doi. 10.1038/leu.2015.9
By:
- Esmailzadeh, S;
- Huang, Y;
- Su, M-W;
- Zhou, Y;
- Jiang, X
Publication type:
Article
Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1267, doi. 10.1038/leu.2014.340
By:
- Fiskus, W;
- Sharma, S;
- Saha, S;
- Shah, B;
- Devaraj, S G T;
- Sun, B;
- Horrigan, S;
- Leveque, C;
- Zu, Y;
- Iyer, S;
- Bhalla, K N
Publication type:
Article
HIF-1α is required for hematopoietic stem cell mobilization and 4-prolyl hydroxylase inhibitors enhance mobilization by stabilizing HIF-1α.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1366, doi. 10.1038/leu.2015.8
By:
- Forristal, C E;
- Nowlan, B;
- Jacobsen, R N;
- Barbier, V;
- Walkinshaw, G;
- Walkley, C R;
- Winkler, I G;
- Levesque, J P
Publication type:
Article
PTPROt-mediated regulation of p53/Foxm1 suppresses leukemic phenotype in a CLL mouse model.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1350, doi. 10.1038/leu.2014.341
By:
- Motiwala, T;
- Kutay, H;
- Zanesi, N;
- Frissora, F W;
- Mo, X;
- Muthusamy, N;
- Jacob, S T
Publication type:
Article
The predominant myeloma clone at diagnosis, CDR3 defined, is constantly detectable across all stages of disease evolution.
Published in:
Leukemia (08876924), 2015, v. 29, n. 6, p. 1435, doi. 10.1038/leu.2015.7
By:
- Puig, N;
- Conde, I;
- Jiménez, C;
- Sarasquete, M E;
- Balanzategui, A;
- Alcoceba, M;
- Quintero, J;
- Chillón, M C;
- Sebastián, E;
- Corral, R;
- Marín, L;
- Gutiérrez, N C;
- Mateos, M-V;
- González-Díaz, M;
- San-Miguel, J F;
- García-Sanz, R
Publication type:
Article

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