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Results: 30

The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor.
Published in:
2013
By:
- Karpova, D;
- Dauber, K;
- Spohn, G;
- Chudziak, D;
- Wiercinska, E;
- Schulz, M;
- Pettit, A R;
- Levesque, J P;
- Romagnoli, B;
- Patel, K;
- Chevalier, E;
- Dembowsky, K;
- Bonig, H
Publication type:
journal article
Disruption of the MYC-miRNA-EZH2 loop to suppress aggressive B-cell lymphoma survival and clonogenicity.
Published in:
2013
By:
- Zhao, X;
- Lwin, T;
- Zhang, X;
- Huang, A;
- Wang, J;
- Marquez, V E;
- Chen-Kiang, S;
- Dalton, W S;
- Sotomayor, E;
- Tao, J
Publication type:
journal article
A genome-wide RNAi screen identifies proteins modulating aberrant FLT3-ITD signaling.
Published in:
2013
By:
- Caldarelli, A;
- Müller, J P;
- Paskowski-Rogacz, M;
- Herrmann, K;
- Bauer, R;
- Koch, S;
- Heninger, A K;
- Krastev, D;
- Ding, L;
- Kasper, S;
- Fischer, T;
- Brodhun, M;
- Böhmer, F-D;
- Buchholz, F
Publication type:
journal article
Galectin-3 in pre-B acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2385, doi. 10.1038/leu.2013.175
By:
- Fei, F;
- Abdel-Azim, H;
- Lim, M;
- Arutyunyan, A;
- von Itzstein, M;
- Groffen, J;
- Heisterkamp, N
Publication type:
Article
A genome-wide RNAi screen identifies proteins modulating aberrant FLT3-ITD signaling.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2301, doi. 10.1038/leu.2013.83
By:
- Caldarelli, A;
- Müller, J P;
- Paskowski-Rogacz, M;
- Herrmann, K;
- Bauer, R;
- Koch, S;
- Heninger, A K;
- Krastev, D;
- Ding, L;
- Kasper, S;
- Fischer, T;
- Brodhun, M;
- Böhmer, F-D;
- Buchholz, F
Publication type:
Article
Disruption of the MYC-miRNA-EZH2 loop to suppress aggressive B-cell lymphoma survival and clonogenicity.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2341, doi. 10.1038/leu.2013.94
By:
- Zhao, X;
- Lwin, T;
- Zhang, X;
- Huang, A;
- Wang, J;
- Marquez, V E;
- Chen-Kiang, S;
- Dalton, W S;
- Sotomayor, E;
- Tao, J
Publication type:
Article
Sporadic and reversible chromothripsis in chronic lymphocytic leukemia revealed by longitudinal genomic analysis.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2376, doi. 10.1038/leu.2013.127
By:
- Bassaganyas, L;
- Beà, S;
- Escaramís, G;
- Tornador, C;
- Salaverria, I;
- Zapata, L;
- Drechsel, O;
- Ferreira, P G;
- Rodriguez-Santiago, B;
- Tubio, J M C;
- Navarro, A;
- Martín-García, D;
- López, C;
- Martínez-Trillos, A;
- López-Guillermo, A;
- Gut, M;
- Ossowski, S;
- López-Otín, C;
- Campo, E;
- Estivill, X
Publication type:
Article
Excess treatment reduction including anthracyclines results in higher incidence of relapse in core binding factor acute myeloid leukemia in children.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2413, doi. 10.1038/leu.2013.153
By:
- Tomizawa, D;
- Tawa, A;
- Watanabe, T;
- Saito, A M;
- Kudo, K;
- Taga, T;
- Iwamoto, S;
- Shimada, A;
- Terui, K;
- Moritake, H;
- Kinoshita, A;
- Takahashi, H;
- Nakayama, H;
- Koh, K;
- Kigasawa, H;
- Kosaka, Y;
- Miyachi, H;
- Horibe, K;
- Nakahata, T;
- Adachi, S
Publication type:
Article
Prognostic impact and landscape of NOTCH1 mutations in chronic lymphocytic leukemia (CLL): a study on 852 patients.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2393, doi. 10.1038/leu.2013.218
By:
- Weissmann, S;
- Roller, A;
- Jeromin, S;
- Hernández, M;
- Abáigar, M;
- Hernández-Rivas, J M;
- Grossmann, V;
- Haferlach, C;
- Kern, W;
- Haferlach, T;
- Schnittger, S;
- Kohlmann, A
Publication type:
Article
In hematopoietic cells with a germline mutation of CBL, loss of heterozygosity is not a signature of juvenile myelo-monocytic leukemia.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2404, doi. 10.1038/leu.2013.203
By:
- Strullu, M;
- Caye, A;
- Cassinat, B;
- Fenneteau, O;
- Touzot, F;
- Blauwblomme, T;
- Rodriguez, R;
- Latour, S;
- Petit, A;
- Barlogis, V;
- Galambrun, C;
- Leblanc, T;
- Baruchel, A;
- Chomienne, C;
- Cavé, H
Publication type:
Article
Granulocyte colony-stimulating factor receptor T595I (T618I) mutation confers ligand independence and enhanced signaling.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2407, doi. 10.1038/leu.2013.164
By:
- Mehta, H M;
- Glaubach, T;
- Long, A;
- Lu, H;
- Przychodzen, B;
- Makishima, H;
- McDevitt, M A;
- Cross, N C P;
- Maciejewski, J;
- Corey, S J
Publication type:
Article
Toward personalized therapy in AML: in vivo benefit of targeting aberrant epigenetics in MLL-PTD-associated AML.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2379, doi. 10.1038/leu.2013.147
By:
- Bernot, K M;
- Siebenaler, R F;
- Whitman, S P;
- Zorko, N A;
- Marcucci, G G;
- Santhanam, R;
- Ahmed, E H;
- Ngangana, M;
- McConnell, K K;
- Nemer, J S;
- Brook, D L;
- Kulp, S K;
- Chen, C S;
- Frankhouser, D;
- Yan, P;
- Bundschuh, R;
- Zhang, X;
- Dorrance, A M;
- Dickerson, K E;
- Jarjoura, D
Publication type:
Article
Imatinib results in better outcomes than HLA-identical sibling transplants in young persons with newly diagnosed chronic-phase chronic myelogenous leukemia.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2410, doi. 10.1038/leu.2013.159
By:
- Jiang, Q;
- Xu, L-P;
- Liu, D-H;
- Liu, K-Y;
- Gale, R P;
- Zhang, M-J;
- Jiang, B;
- Zhang, X-H;
- Wang, Y;
- Chen, S-S;
- Zhao, X-Y;
- Chen, H;
- Jiang, H;
- Chen, Y-H;
- Han, W;
- Qin, Y-Z;
- Liu, Y-R;
- Lai, Y-Y;
- Lv, M;
- Huang, X-J
Publication type:
Article
Understanding the interplay between the proteasome pathway and autophagy in response to dual PI3K/mTOR inhibition in myeloma cells is essential for their effective clinical application.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2397, doi. 10.1038/leu.2013.150
By:
- Aronson, L I;
- Davenport, E L;
- Mirabella, F;
- Morgan, G J;
- Davies, F E
Publication type:
Article
Detection of PICALM-MLLT10 (CALM-AF10) and outcome in children with T-lineage acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2419, doi. 10.1038/leu.2013.149
By:
- Lo Nigro, L;
- Mirabile, E;
- Tumino, M;
- Caserta, C;
- Cazzaniga, G;
- Rizzari, C;
- Silvestri, D;
- Buldini, B;
- Barisone, E;
- Casale, F;
- Luciani, M;
- Locatelli, F;
- Messina, C;
- Micalizzi, C;
- Pession, A;
- Parasole, R;
- Santoro, N;
- Masera, G;
- Basso, G;
- Aricò, M
Publication type:
Article
The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2322, doi. 10.1038/leu.2013.266
By:
- Karpova, D;
- Dauber, K;
- Spohn, G;
- Chudziak, D;
- Wiercinska, E;
- Schulz, M;
- Pettit, A R;
- Levesque, J P;
- Romagnoli, B;
- Patel, K;
- Chevalier, E;
- Dembowsky, K;
- Bonig, H
Publication type:
Article
Treatment outcomes in patients with relapsed and refractory multiple myeloma and high-risk cytogenetics receiving single-agent carfilzomib in the PX-171-003-A1 study.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2351, doi. 10.1038/leu.2013.152
By:
- Jakubowiak, A J;
- Siegel, D S;
- Martin, T;
- Wang, M;
- Vij, R;
- Lonial, S;
- Trudel, S;
- Kukreti, V;
- Bahlis, N;
- Alsina, M;
- Chanan-Khan, A;
- Buadi, F;
- Reu, F J;
- Somlo, G;
- Zonder, J;
- Song, K;
- Stewart, A K;
- Stadtmauer, E;
- Harrison, B L;
- Wong, A F
Publication type:
Article
Aberrant expression of CCR4 in diffuse large B-cell lymphoma, not otherwise specified.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2382, doi. 10.1038/leu.2013.128
By:
- Nakayama, S;
- Yokote, T;
- Hirata, Y;
- Iwaki, K;
- Akioka, T;
- Miyoshi, T;
- Hiraoka, N;
- Takayama, A;
- Nishiwaki, U;
- Masuda, Y;
- Nishimura, Y;
- Tsuji, M;
- Hanafusa, T
Publication type:
Article
Leukemia-initiating cell activity requires calcineurin in T-cell acute lymphoblastic leukemia.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2289, doi. 10.1038/leu.2013.156
By:
- Gachet, S;
- Genescà, E;
- Passaro, D;
- Irigoyen, M;
- Alcalde, H;
- Clémenson, C;
- Poglio, S;
- Pflumio, F;
- Janin, A;
- Lasgi, C;
- Dodier, S;
- Soyer, M;
- Duménil, G;
- Ghysdael, J
Publication type:
Article
Polyclonal immune activation and marrow plasmacytosis in multiple myeloma patients receiving long-term lenalidomide therapy: incidence and prognostic significance.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2422, doi. 10.1038/leu.2013.126
By:
- Zamarin, D;
- Devlin, S M;
- Arcila, M E;
- Landau, H;
- Lesokhin, A;
- Lendvai, N;
- Chung, D J;
- Chimento, D;
- Weltz, J;
- Babu, D;
- Giralt, S;
- Hassoun, H
Publication type:
Article
Functional characterization of Foxp3-specific spontaneous immune responses.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2332, doi. 10.1038/leu.2013.196
By:
- Larsen, S K;
- Munir, S;
- Woetmann, A;
- Frøsig, T M;
- Odum, N;
- Svane, I M;
- Becker, J C;
- Andersen, M H
Publication type:
Article
Vertebral augmentation in the treatment of pathologic compression fractures in 792 patients with multiple myeloma.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2391, doi. 10.1038/leu.2013.162
By:
- Erdem, E;
- Samant, R;
- Malak, S F;
- Culp, W C;
- Brown, A;
- Peterson, L;
- Lensing, S;
- Barlogie, B
Publication type:
Article
NUP98/JARID1A is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX gene expression pattern.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2280, doi. 10.1038/leu.2013.87
By:
- de Rooij, J D E;
- Hollink, I H I M;
- Arentsen-Peters, S T C J M;
- van Galen, J F;
- Berna Beverloo, H;
- Baruchel, A;
- Trka, J;
- Reinhardt, D;
- Sonneveld, E;
- Zimmermann, M;
- Alonzo, T A;
- Pieters, R;
- Meshinchi, S;
- van den Heuvel-Eibrink, M M;
- Zwaan, C Michel
Publication type:
Article
JAK inhibitors suppress t(8;21) fusion protein-induced leukemia.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2272, doi. 10.1038/leu.2013.197
By:
- Lo, M-C;
- Peterson, L F;
- Yan, M;
- Cong, X;
- Hickman, J H;
- DeKelver, R C;
- Niewerth, D;
- Zhang, D-E
Publication type:
Article
SOX11 overexpression is a specific marker for mantle cell lymphoma and correlates with t(11;14) translocation, CCND1 expression and an adverse prognosis.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2388, doi. 10.1038/leu.2013.141
By:
- Meggendorfer, M;
- Kern, W;
- Haferlach, C;
- Haferlach, T;
- Schnittger, S
Publication type:
Article
Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2357, doi. 10.1038/leu.2013.172
By:
- Schmidt, J;
- Braggio, E;
- Kortuem, K M;
- Egan, J B;
- Zhu, Y X;
- Xin, C S;
- Tiedemann, R E;
- Palmer, S E;
- Garbitt, V M;
- McCauley, D;
- Kauffman, M;
- Shacham, S;
- Chesi, M;
- Bergsagel, P L;
- Stewart, A K
Publication type:
Article
Heterogeneity of outcome with single-agent carfilzomib: all relapsed/refractory myelomas are not created equal.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2269, doi. 10.1038/leu.2013.161
By:
- Usmani, S Z;
- Hoering, A
Publication type:
Article
Small-molecule multi-targeted kinase inhibitor RGB-286638 triggers P53-dependent and -independent anti-multiple myeloma activity through inhibition of transcriptional CDKs.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2366, doi. 10.1038/leu.2013.194
By:
- Cirstea, D;
- Hideshima, T;
- Santo, L;
- Eda, H;
- Mishima, Y;
- Nemani, N;
- Hu, Y;
- Mimura, N;
- Cottini, F;
- Gorgun, G;
- Ohguchi, H;
- Suzuki, R;
- Loferer, H;
- Munshi, N C;
- Anderson, K C;
- Raje, N
Publication type:
Article
Associations between genome-wide Native American ancestry, known risk alleles and B-cell ALL risk in Hispanic children.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2416, doi. 10.1038/leu.2013.130
By:
- Walsh, K M;
- Chokkalingam, A P;
- Hsu, L-I;
- Metayer, C;
- de Smith, A J;
- Jacobs, D I;
- Dahl, G V;
- Loh, M L;
- Smirnov, I V;
- Bartley, K;
- Ma, X;
- Wiencke, J K;
- Barcellos, L F;
- Wiemels, J L;
- Buffler, P A
Publication type:
Article
Modeling tumor-host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor biology and evaluate targeted therapy.
Published in:
Leukemia (08876924), 2013, v. 27, n. 12, p. 2311, doi. 10.1038/leu.2013.131
By:
- Herman, S E M;
- Sun, X;
- McAuley, E M;
- Hsieh, M M;
- Pittaluga, S;
- Raffeld, M;
- Liu, D;
- Keyvanfar, K;
- Chapman, C M;
- Chen, J;
- Buggy, J J;
- Aue, G;
- Tisdale, J F;
- Pérez-Galán, P;
- Wiestner, A
Publication type:
Article