Quantitative SPECT of DMSA uptake by the kidneys: Assessment of reproducibility.

Groshar, David; Moskovitz, Boaz; Issaq, Elias; Nativ, Ofer

The article focuses on the quantitative SPECT of DMSA uptake by the kidneys. Since its introduction in the early 1970s, the technetium dimercapto-succinic acid (Tc-DmSA) scan has been used as a static imaging agent to detect cortical defects in the kidneys. Scintigraphy provides an image of the functional renal parenchyma, and the renal uptake of Tc-DMSA has been shown to correlate well with the effective renal plasma flow (ERPF), glomerular filtration rate (GFR) and creatinine clearance. Thus the renal uptake of Tc-DMSA provides a practical index for evaluation of individual renal function.

KIDNEY diseases; TECHNETIUM; SUCCINIC acid; KIDNEYS; GLOMERULAR filtration rate; RENAL hypertension

Kidney International, 1997, Vol 52, Issue 3, p817

0085-2538

Academic Journal

10.1038/ki.1997.399