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FIH-Dependent Asparaginyl Hydroxylation of Ankyrin Repeat Domain-Containing Proteins.
- Published in:
- Annals of the New York Academy of Sciences, 2009, v. 1177, n. 1, p. 9, doi. 10.1111/j.1749-6632.2009.05042.x
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- Article
Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin.
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- EMBO Reports, 2019, v. 20, n. 1, p. N.PAG, doi. 10.15252/embr.201846401
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- Article
Capture-C reveals preformed chromatin interactions between HIF-binding sites and distant promoters.
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- EMBO Reports, 2016, v. 17, n. 10, p. 1410, doi. 10.15252/embr.201642198
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- Article
Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2.
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- EMBO Reports, 2014, v. 15, n. 1, p. 70, doi. 10.1002/embr.201337642
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- Article
The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity.
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- EMBO Reports, 2012, v. 13, n. 3, p. 251, doi. 10.1038/embor.2012.9
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- Article
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.
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- EMBO Reports, 2011, v. 12, n. 5, p. 463, doi. 10.1038/embor.2011.43
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- Publication type:
- Article
The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens.
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- EMBO Reports, 2011, v. 12, n. 1, p. 63, doi. 10.1038/embor.2010.170
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- Article
Reversion of lethality and growth defects in Fatiga oxygen-sensor mutant flies by loss of Hypoxia-Inducible Factor-α/Sima.
- Published in:
- EMBO Reports, 2005, v. 6, n. 11, p. 1070, doi. 10.1038/sj.embor.7400528
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- Article
A global view of the aspiring physician-scientist.
- Published in:
- 2022
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- Publication type:
- Interview
Genetic basis of oxygen sensing in the carotid body: HIF2α and an isoform switch in cytochrome c oxidase subunit 4.
- Published in:
- Science Signaling, 2020, v. 13, n. 615, p. 1, doi. 10.1126/scisignal.aba1302
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- Article
Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma.
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- Life Science Alliance, 2023, v. 6, n. 4, p. 1, doi. 10.26508/lsa.202201756
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- Publication type:
- Article
Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors.
- Published in:
- Angewandte Chemie International Edition, 2012, v. 51, n. 27, p. 6672, doi. 10.1002/anie.201202000
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- Publication type:
- Article
Independent function of two destruction domains in hypoxia-inducible factor-a chains activated by prolyl hydroxylation.
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- EMBO Journal, 2001, v. 20, n. 18, p. 5197, doi. 10.1093/emboj/20.18.5197
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- Article
On the pivotal role of PPARa in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury.
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- FASEB Journal, 2016, v. 30, n. 8, p. 2684, doi. 10.1096/fj.201500094R
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- Publication type:
- Article
Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2α gain-of-function mutation.
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- FASEB Journal, 2011, v. 25, n. 6, p. 2001, doi. 10.1096/fj.10-177378
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- Publication type:
- Article
Leu-574 of human HIF-1α is a molecular determinant of prolyl hydroxylation.
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- FASEB Journal, 2004, v. 18, n. 9, p. 1028, doi. 10.1096/fj.03-1233fje
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- Publication type:
- Article
Widespread, hypoxia‐inducible expression of HIF‐2α in distinct cell populations of different organs.
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- FASEB Journal, 2003, v. 17, n. 2, p. 271, doi. 10.1096/fj.02-0445fje
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- Publication type:
- Article
Genetic Analysis of Pathways Regulated by the von Hippel-Lindau Tumor Suppressor in Caenorhabditis elegans.
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- PLoS Biology, 2004, v. 2, n. 10, p. 1549, doi. 10.1371/journal.pbio.0020289
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- Publication type:
- Article
Genetic Analysis of Pathways Regulated by the von Hippel-Lindau Tumor Suppressor in Caenorhabditis elegans.
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- PLoS Biology, 2004, v. 2, n. 9, p. 1, doi. 10.1371/journal.pbio.0020289
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- Publication type:
- Article
Oxygen sensing by HIF hydroxylases.
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- Nature Reviews Molecular Cell Biology, 2004, v. 5, n. 5, p. 343, doi. 10.1038/nrm1366
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- Article
Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia.
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- BJU International, 2008, v. 101, p. 8, doi. 10.1111/j.1464-410X.2008.07642.x
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- Publication type:
- Article
Cellular oxygen sensing in health and disease.
- Published in:
- Pediatric Nephrology, 2008, v. 23, n. 5, p. 681, doi. 10.1007/s00467-007-0632-x
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- Publication type:
- Article
Harveian Oration 2020: Elucidation of molecular oxygen sensing mechanisms in human cells: implications for medicine.
- Published in:
- Clinical Medicine, 2022, v. 22, n. 1, p. 23, doi. 10.7861/clinmed.ed.22.1.harv
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- Article
Delivery of erythropoietin by encapsulated myoblasts in a genetic model of severe anemia.
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- Kidney International, 2002, v. 62, n. 4, p. 1395, doi. 10.1111/j.1523-1755.2002.kid574.x
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- Publication type:
- Article
The interstitial response to renal injury: Fibroblast-like cells show phenotypic changes and have reduced potential for erythropoietin gene expression.
- Published in:
- Kidney International, 1997, v. 52, n. 3, p. 715, doi. 10.1038/ki.1997.387
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- Article
Oxygen regulated gene expression: Erythropoietin as a model system.
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- Kidney International, 1997, v. 51, n. 2, p. 514, doi. 10.1038/ki.1997.72
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- Publication type:
- Article
Sites of erythropoietin production.
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- Kidney International, 1997, v. 51, n. 2, p. 393, doi. 10.1038/ki.1997.52
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- Publication type:
- Article
U.K. Prospective Diabetes Study XV: Relationship of renin-angiotensin system gene polymorphisms with microalbuminuria in NIDDM.
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- Kidney International, 1995, v. 48, n. 6, p. 1907, doi. 10.1038/ki.1995.490
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- Publication type:
- Article
Identification of the renal erythropoietin-producing cells using transgenic mice.
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- Kidney International, 1993, v. 44, n. 5, p. 1149, doi. 10.1038/ki.1993.362
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- Article
Molecular biology of erythropoietin.
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- Kidney International, 1993, v. 44, n. 4, p. 887, doi. 10.1038/ki.1993.327
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- Article
Distribution of erythropoietin producing cells in rat kidneys during hypoxic hypoxia.
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- Kidney International, 1993, v. 43, n. 4, p. 815, doi. 10.1038/ki.1993.115
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- Publication type:
- Article
Rapid oxygen-dependent changes in erythropoietin mRNA in perfused rat kidneys: Evidence against mediation by cAMP.
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- Kidney International, 1992, v. 41, n. 6, p. 1581, doi. 10.1038/ki.1992.228
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- Article
Organ distribution of erythropoietin messenger RNA in normal and uremic rats.
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- Kidney International, 1991, v. 40, n. 1, p. 69, doi. 10.1038/ki.1991.181
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- Publication type:
- Article
87-Rubidium NMR: A novel method of measuring cation flux in intact kidney.
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- Kidney International, 1989, v. 35, n. 5, p. 1249, doi. 10.1038/ki.1989.117
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- Publication type:
- Article
Acute renal failure in hemorrhagic hypotension: Cellular energetics and renal function.
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- Kidney International, 1986, v. 30, n. 3, p. 355, doi. 10.1038/ki.1986.192
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- Publication type:
- Article
ExCITED about HIF.
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- Nature Structural Biology, 2003, v. 10, n. 7, p. 501, doi. 10.1038/nsb0703-501
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- Article
Dynamic regulatory network controlling T<sub>H</sub>17 cell differentiation.
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- Nature, 2013, v. 496, n. 7446, p. 461, doi. 10.1038/nature11981
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- Article
Erratum. Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion. Diabetes 2015;64:733-745.
- Published in:
- 2021
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- Correction Notice
Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors.
- Published in:
- Angewandte Chemie, 2012, v. 124, n. 27, p. 6776, doi. 10.1002/ange.201202000
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- Publication type:
- Article
PHD2 inactivation in Type I cells drives HIF‐2α‐dependent multilineage hyperplasia and the formation of paraganglioma‐like carotid bodies.
- Published in:
- Journal of Physiology, 2018, v. 596, n. 18, p. 4393, doi. 10.1113/JP275996
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- Publication type:
- Article
Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway.
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- Journal of Physiology, 2016, v. 594, n. 5, p. 1179, doi. 10.1113/JP271050
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- Publication type:
- Article
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.
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- Journal of Physiology, 2013, v. 591, n. 14, p. 3565, doi. 10.1113/jphysiol.2012.247254
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- Publication type:
- Article
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer.
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- Journal of Physiology, 2013, v. 591, n. 8, p. 2027, doi. 10.1113/jphysiol.2013.251470
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- Publication type:
- Article
Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice.
- Published in:
- Journal of Physiology, 2012, v. 590, n. 16, p. 4079, doi. 10.1113/jphysiol.2012.232884
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- Publication type:
- Article
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status.
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- Journal of Physiology, 2008, v. 586, n. 24, p. 5999, doi. 10.1113/jphysiol.2008.160960
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- Publication type:
- Article
Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism.
- Published in:
- Human Molecular Genetics, 2010, v. 19, n. 19, p. 3844, doi. 10.1093/hmg/ddq305
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- Publication type:
- Article
PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase.
- Published in:
- Human Molecular Genetics, 2010, v. 19, n. 2, p. 217, doi. 10.1093/hmg/ddp480
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- Publication type:
- Article
Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer.
- Published in:
- Nature Communications, 2016, v. 7, n. 10, p. 13183, doi. 10.1038/ncomms13183
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- Publication type:
- Article
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
- Published in:
- Nature Communications, 2016, v. 7, n. 8, p. 12673, doi. 10.1038/ncomms12673
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- Publication type:
- Article
Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia- Inducible Factor 1α (HIF-1α).
- Published in:
- PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016210
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- Publication type:
- Article