Works matching AU Chen, Shu G.

Results: 36

Skin α-Synuclein Aggregation Seeding Activity as a Novel Biomarker for Parkinson Disease.

Published in:

JAMA Neurology, 2021, v. 78, n. 1, p. 30, doi. 10.1001/jamaneurol.2020.3311

By:

Wang, Zerui;
Becker, Katelyn;
Donadio, Vincenzo;
Siedlak, Sandra;
Yuan, Jue;
Rezaee, Masih;
Incensi, Alex;
Kuzkina, Anastasia;
Orrú, Christina D.;
Tatsuoka, Curtis;
Liguori, Rocco;
Gunzler, Steven A.;
Caughey, Byron;
Jimenez-Capdeville, Maria E.;
Zhu, Xiongwei;
Doppler, Kathrin;
Cui, Li;
Chen, Shu G.;
Ma, Jiyan;
Zou, Wen-Quan

Publication type:

Article

Molecular Pathology of Fatal Familial Insomnia.

Published in:

Brain Pathology, 1998, v. 8, n. 3, p. 539, doi. 10.1111/j.1750-3639.1998.tb00176.x

By:

Parchi, Piero;
Petersen, Robert B.;
Chen, Shu G.;
Autilio-Gambetti, L.;
Capellari, Sabina;
Monari, Lucia;
Cortelli, Pietro;
Montagna, Pasquale;
Lugaresi, Elio;
Gambetti, Pierluigi

Publication type:

Article

Fatal Familial Insomnia and Familial Creutzfeldt-Jakob Disease: Clinical, Pathological and Molecular Features.

Published in:

Brain Pathology, 1995, v. 5, n. 1, p. 43, doi. 10.1111/j.1750-3639.1995.tb00576.x

By:

Gambetti, Pierluigi;
Parchi, Piero;
Petersen, Robert B.;
Chen, Shu G.;
Lugaresi, Elio

Publication type:

Article

Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson's disease and dementia with Lewy bodies.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01175-w

By:

Bargar, Connor;
Wang, Wen;
Gunzler, Steven A.;
LeFevre, Alexandra;
Wang, Zerui;
Lerner, Alan J.;
Singh, Neena;
Tatsuoka, Curtis;
Appleby, Brian;
Zhu, Xiongwei;
Xu, Rong;
Haroutunian, Vahram;
Zou, Wen-Quan;
Ma, Jiyan;
Chen, Shu G.

Publication type:

Article

Paradoxical Role of Prion Protein Aggregates in Redox-Iron Induced Toxicity.

Published in:

PLoS ONE, 2010, v. 5, n. 7, p. 1, doi. 10.1371/journal.pone.0011420

By:

Das, Dola;
Xiu Luo;
Singh, Ajay;
Gu, Yaping;
Ghosh, Soumya;
Mukhopadhyay, Chinmay K.;
Chen, Shu G.;
Sy, Man-Sun;
Kong, Qingzhong;
Singh, Neena

Publication type:

Article

Chronic Wasting Disease of Elk: Transmissibility to Humans Examined by Transgenic Mouse Models.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 35, p. 7944, doi. 10.1523/JNEUROSCI.2467-05.2005

By:

Qingzhong Kong;
Shenghai Huang;
Wenquan Zou;
Vanegas, Difernando;
Meiling Wang;
Di Wu;
Jue Yuan;
Mengjie Zheng;
Hua Bai;
Huayun Deng;
Chen, Ken;
Jenny, Allen L.;
O'Rourke, Katherine;
Belay, Ermias D.;
Schonberger, Lawrence B.;
Petersen, Robert B.;
Man-Sun Sy;
Chen, Shu G.;
Gambetti, Pierluigi

Publication type:

Article

Protease-Resistant Human Prion Protein and Ferritin Are Cotransported across Caco-2 Epithelial Cells: Implications for Species Barrier in Prion Uptake from the Intestine.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 50, p. 11280, doi. 10.1523/JNEUROSCI.2864-04.2004

By:

Mishra, Ravi Shankar;
Basu, Subhabrata;
Yaping Gu;
Xiu Luo;
Wen-Quan Zou;
Mishra, Richa;
Ruliang Li;
Chen, Shu G.;
Gambetti, Pierluigi;
Fujioka, Hisashi;
Singh, Neena

Publication type:

Article

Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 5, p. 1322, doi. 10.1093/hmg/ddu542

By:

Johnson, William M.;
Yao, Chen;
Siedlak, Sandra L.;
Wang, Wenzhang;
Zhu, Xiongwei;
Caldwell, Guy A.;
Wilson-Delfosse, Amy L.;
Mieyal, John J.;
Chen, Shu G.

Publication type:

Article

Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity.

Published in:

Human Molecular Genetics, 2013, v. 22, n. 2, p. 328, doi. 10.1093/hmg/dds431

By:

Yao, Chen;
Johnson, William M.;
Gao, Yue;
Wang, Wen;
Zhang, Jinwei;
Deak, Maria;
Alessi, Dario R.;
Zhu, Xiongwei;
Mieyal, John J.;
Roder, Hanno;
Wilson-Delfosse, Amy L.;
Chen, Shu G.

Publication type:

Article

Potential long‐term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1248, doi. 10.1002/alz.12465

By:

Zheng, Chunlei;
Fillmore, Nathanael R.;
Ramos‐Cejudo, Jaime;
Brophy, Mary;
Osorio, Ricardo;
Gurney, Mark E.;
Qiu, Wei Qiao;
Au, Rhoda;
Perry, George;
Dubreuil, Maureen;
Chen, Shu G;
Qi, Xin;
Davis, Pamela B;
Do, Nhan;
Xu, Rong

Publication type:

Article

Overexpression of GRK2 in Alzheimer Disease and in a Chronic Hypoperfusion Rat Model is an Early Marker of Brain Mitochondrial Lesions.

Published in:

Neurotoxicity Research, 2006, v. 10, n. 1, p. 43, doi. 10.1007/BF03033333

By:

Obrenovich, Mark E.;
Smith, Mark A.;
Siedlak, Sandra L.;
Chen, Shu G.;
De la Torre, Jack C.;
Perry, George;
Aliev, Gjumrakch

Publication type:

Article

Novel strain properties distinguishing sporadic prion diseases sharing prion protein genotype and prion type.

Published in:

Scientific Reports, 2017, p. 38280, doi. 10.1038/srep38280

By:

Cracco, Laura;
Notari, Silvio;
Cali, Ignazio;
Sy, Man-Sun;
Chen, Shu G.;
Cohen, Mark L.;
Ghetti, Bernardino;
Appleby, Brian S.;
Zou, Wen-Quan;
Caughey, Byron;
Safar, Jiri G.;
Gambetti, Pierluigi

Publication type:

Article

Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans.

Published in:

Scientific Reports, 2016, p. 34477, doi. 10.1038/srep34477

By:

Chen, Shu G.;
Stribinskis, Vilius;
Rane, Madhavi J.;
Demuth, Donald R.;
Gozal, Evelyne;
Roberts, Andrew M.;
Jagadapillai, Rekha;
Liu, Ruolan;
Choe, Kyonghwan;
Shivakumar, Bhooma;
Son, Francheska;
Jin, Shunying;
Kerber, Richard;
Adame, Anthony;
Masliah, Eliezer;
Friedland, Robert P.

Publication type:

Article

Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats.

Published in:

Journal of Cellular & Molecular Medicine, 2009, v. 13, n. 2, p. 320, doi. 10.1111/j.1582-4934.2008.00324.x

By:

Aliev, Gjumrakch;
Jiankang Liu;
Justin C. Shenk;
Fischbach, Kathryn;
Pacheco, Gerardo J.;
Chen, Shu G.;
Obrenovich, Mark E.;
Ward, Walter F.;
Richardson, Arlan G.;
Smith, Mark A.;
Gasimov, Eldar;
George Perry;
Ames, Bruce N.

Publication type:

Article

LRRK2 protein is a component of Lewy bodies.

Published in:

2006

By:

Zhu X;
Siedlak SL;
Smith MA;
Perry G;
Chen SG;
Zhu, Xiongwei;
Siedlak, Sandra L;
Smith, Mark A;
Perry, George;
Chen, Shu G

Publication type:

Letter

Molecular basis of phenotypic variability in sporadc creudeldt-jakob disease.

Published in:

Annals of Neurology, 1996, v. 39, n. 6, p. 767, doi. 10.1002/ana.410390613

By:

Parchi, Piero;
Castellani, Rudolph;
Capellari, Sabina;
Ghetti, Bernardino;
Young, Katherine;
Chen, Shu G.;
Farlow, Martin;
Dickson, Dennis W.;
Sima, Anders A. F.;
Trojanowski, John Q.;
Petersen, Robert B.;
Gambetti, Pierluigi

Publication type:

Article

Regional distribution of protease-resistant prion protein in fatal familial insomnia.

Published in:

Annals of Neurology, 1995, v. 38, n. 1, p. 21, doi. 10.1002/ana.410380107

By:

Parchi, Piero;
Castellani, Rudy;
Cortelli, Pietro;
Montagna, Pasquale;
Chen, Shu G.;
Petersen, Robert B.;
Manetto, Valeria;
Vnencak-Jones, Cindy L.;
McLean, Michael J.;
Sheller, James R.;
Lugaresi, Elio;
Autilio-Gambetti, Lucila;
Gambetti, Pierluigi

Publication type:

Article

P4-162: LRRK2 in Lewy bodies of Parkinson’s disease and dementia with Lewy bodies

Published in:

2006

By:

Smith, Mark A.;
Zhu, Xiongwei;
Babar, Asim;
Siedlak, Sandra L.;
Yang, Qiwei;
Ito, Genta;
Iwatsubo, Takeshi;
Perry, George;
Chen, Shu G.

Publication type:

Abstract

P1-423: Functional studies of a novel protein kinase LRRK2 provide insights into pathogenesis of Parkinson’s disease

Published in:

2006

By:

Guo, Luxuan;
Wang, Wen;
Gandhi, Payal N.;
Wilson-Delfosse, Amy L.;
Chen, Shu G.

Publication type:

Abstract

P4-162: LRRK2 in Lewy bodies of Parkinson’s disease and dementia with Lewy bodies

Published in:

2006

By:

Smith, Mark A.;
Zhu, Xiongwei;
Babar, Asim;
Siedlak, Sandra L.;
Yang, Qiwei;
Ito, Genta;
Iwatsubo, Takeshi;
Perry, George;
Chen, Shu G.

Publication type:

Abstract

P1-423: Functional studies of a novel protein kinase LRRK2 provide insights into pathogenesis of Parkinson’s disease

Published in:

2006

By:

Guo, Luxuan;
Wang, Wen;
Gandhi, Payal N.;
Wilson-Delfosse, Amy L.;
Chen, Shu G.

Publication type:

Abstract

The primary pathogenetic role of vascular contains vasoactive substances, hypoperfusion, mitochondria failure and oxidative stress in aging and Alzheimer disease

Published in:

2005

By:

Aliev, Gjumrakch;
Perry, George;
Liu, Jiankang;
Smith, Mark A.;
Chen, Shu G.;
Ames, Bruce N.;
de la Torre, Jack C.

Publication type:

Abstract

LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 9, p. 1931, doi. 10.1093/hmg/dds003

By:

Wang, Xinglong;
Yan, Michael H.;
Fujioka, Hisashi;
Liu, Jun;
Wilson-Delfosse, Amy;
Chen, Shu G.;
Perry, George;
Casadesus, Gemma;
Zhu, Xiongwei

Publication type:

Article

Diagnostic value of skin RT-QuIC in Parkinson's disease: a two-laboratory study.

Published in:

NPJ Parkinson's Disease, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41531-021-00242-2

By:

Kuzkina, Anastasia;
Bargar, Connor;
Schmitt, Daniela;
Rößle, Jonas;
Wang, Wen;
Schubert, Anna-Lena;
Tatsuoka, Curtis;
Gunzler, Steven A.;
Zou, Wen-Quan;
Volkmann, Jens;
Sommer, Claudia;
Doppler, Kathrin;
Chen, Shu G.

Publication type:

Article

DNA Aptamers That Bind to PrP C and Not Prp Sc Show Sequence and Structure Specificity.

Published in:

Experimental Biology & Medicine, 2006, v. 231, n. 2, p. 204, doi. 10.1177/153537020623100211

By:

Takemura, Kaori;
Wang, Ping;
Vorberg, Ina;
Surewicz, Witold;
Priola, Suzette A.;
Kanthasamy, Anumantha;
Pottathil, Ravi;
Chen, Shu G.;
Sreevatsan, Srinand

Publication type:

Article

Sensitive Detection of Prion Protein in Human Urine.

Published in:

Experimental Biology & Medicine, 2005, v. 230, n. 5, p. 343, doi. 10.1177/153537020523000508

By:

Narang, Harash K.;
Dagdanova, Ayuna;
Xie, Zhiliang;
Yang, Qiwei;
Chen, Shu G.

Publication type:

Article

Cryptic Peptides of the Kringle Domains Preferentially Bind to Disease-Associated Prion Protein.

Published in:

Journal of Alzheimer's Disease, 2009, v. 16, n. 2, p. 421, doi. 10.3233/JAD-2009-0980

By:

Hatcher, Kristen;
Zheng, Jian;
Chen, Shu G.

Publication type:

Article

Molecular profiling of paired helical filaments: Commentary on: Quantitative assessment of glycolipid and protein associated with paired helical filament preparations from Alzheimer's diseased brain by Warren J. Goux, Bingcam Liu, Abdurahman M. Shu...

Published in:

Journal of Alzheimer's Disease, 2001, v. 3, n. 5, p. 467, doi. 10.3233/JAD-2001-3505

By:

Chen, Shu G.

Publication type:

Article

Gut–microbiota–microglia–brain interactions in Alzheimer's disease: knowledge-based, multi-dimensional characterization.

Published in:

Alzheimer's Research & Therapy, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13195-021-00917-1

By:

Wang, QuanQiu;
Davis, Pamela B.;
Qi, Xin;
Chen, Shu G.;
Gurney, Mark E.;
Perry, George;
Doraiswamy, P. Murali;
Xu, Rong

Publication type:

Article

A minimally invasive biomarker for sensitive and accurate diagnosis of Parkinson's disease.

Published in:

Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01873-1

By:

Wang, Zerui;
Gilliland, Tricia;
Kim, Hyun Jo;
Gerasimenko, Maria;
Sajewski, Kailey;
Camacho, Manuel V.;
Bebek, Gurkan;
Chen, Shu G.;
Gunzler, Steven A.;
Kong, Qingzhong

Publication type:

Article

Assessing Prion Infectivity of Human Urine in Sporadic Creutzfeldt-Jakob Disease.

Published in:

Emerging Infectious Diseases, 2012, v. 18, n. 1, p. 21, doi. 10.3201/eid1801.110589

By:

Notari, Silvio;
Qing, Liuting;
Pocchiari, Maurizio;
Dagdanova, Ayuna;
Hatcher, Kristin;
Dogterom, Arend;
Groisman, Jose F.;
Lumholtz, Ib Bo;
Puopolo, Maria;
Lasmezas, Corinne;
Chen, Shu G.;
Kong, Qingzhong;
Gambetti, Pierluigi

Publication type:

Article

Sporadic and familial CJD: classification and characterisation.

Published in:

British Medical Bulletin, 2003, v. 66, n. 1, p. 213, doi. 10.1093/bmb/66.1.213

By:

Pierluigi Gambetti;
Qingzhong Kong;
Wenquan Zou;
Piero Parchi;
Shu G Chen

Publication type:

Article

Absence of protease-resistant prion protein in the cerebrospinal fluid of Creutzfeldt-Jakob disease.

Published in:

Journal of Pathology, 2001, v. 194, n. 1, p. 9, doi. 10.1002/path.872

By:

Wong, Boon-Seng;
Green, Alison J. E.;
Li, Ruliang;
Xie, Zhiliang;
Pan, Tao;
Liu, Tong;
Chen, Shu G.;
Gambetti, Pierluigi;
Sy, Man-Sun

Publication type:

Article

LRRK2 in Parkinson's disease and dementia with Lewy bodies.

Published in:

Molecular Neurodegeneration, 2006, v. 1, p. 17, doi. 10.1186/1750-1326-1-17

By:

Xiongwei Zhu;
Babar, Asim;
Siedlak, Sandra L.;
Qiwei Yang;
Ito, Genta;
Iwatsubo, Takeshi;
Smith, Mark A.;
Perry, George;
Chen, Shu G.

Publication type:

Article

Leucine-Rich Repeat Kinase 2 Colocalizes with α-Synuclein in Parkinson’s Disease, but Not Tau-Containing Deposits in Tauopathies.

Published in:

Neurodegenerative Diseases, 2008, v. 5, n. 3/4, p. 222, doi. 10.1159/000113708

By:

Perry, George;
Xiongwei Zhu;
Babar, Asim K.;
Siedlak, Sandra L.;
Qiwei Yang;
Ito, Genta;
Iwatsubo, Takeshi;
Smith, Mark A.;
Chen, Shu G.

Publication type:

Article

Divalent metal transporter, iron, and Parkinson's disease: A pathological relationship.

Published in:

Cell Research, 2010, v. 20, n. 4, p. 397, doi. 10.1038/cr.2010.39

By:

Hyun-pil Lee;
Xiongwei Zhu;
Gang Liu;
Chen, Shu G.;
Perry, George;
Smith, Mark A.;
Hyoung-gon Lee

Publication type:

Article