Works matching DE "HISTONE deacetylase inhibitors"

Results: 1751

Pancreatic Cancer.

Published in:

Innovation, 2011, v. 10, n. 3, p. 47

By:

Koeffler, H. Philip

Publication type:

Article

Masking the Bioactivity of Hydroxamic Acids by Coordination to Cobalt: Towards Bioreductive Anticancer Agents.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 46, p. 1, doi. 10.1002/chem.202401724

By:

Goodman, David M.;
Ritter, Cornelia U.;
Chen, Erin;
Tong, Kelvin K. H.;
Riisom, Mie;
Söhnel, Tilo;
Jamieson, Stephen M. F.;
Anderson, Robert F.;
Brothers, Penelope J.;
Ware, David C.;
Hartinger, Christian G.

Publication type:

Article

Bioorthogonal Drug Release from Nanometric Micelles in Living Cells.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 43, p. 1, doi. 10.1002/chem.202301359

By:

Madegard, Léa;
Girard, Melissa;
Yaw, Benjamin Riss;
Porte, Karine;
Audisio, Davide;
Papot, Sébastien;
Taran, Frédéric

Publication type:

Article

Epigenetic reprogramming of T cells: unlocking new avenues for cancer immunotherapy.

Published in:

Cancer & Metastasis Reviews, 2024, v. 43, n. 1, p. 175, doi. 10.1007/s10555-024-10167-w

By:

Singh, Vipin;
Nandi, Sandhik;
Ghosh, Aritra;
Adhikary, Santanu;
Mukherjee, Shravanti;
Roy, Siddhartha;
Das, Chandrima

Publication type:

Article

Neuroscience: Drugs help to dull bad memories.

Published in:: Nature, 2014, v. 505, n. 7484, p. 457, doi. 10.1038/505457a
Publication type:: Article

Repurposing bempedoic acid as a histone deacetylase 6 inhibitor.

Published in:

International Journal of Epigenetics, 2023, v. 3, n. 1, p. N.PAG, doi. 10.3892/ije.2023.15

By:

Ediriweera, Meran Keshawa;
Rajan, Priyanka;
Cho, Somi Kim

Publication type:

Article

Regulating type III interferon.

Published in:

Nature Immunology, 2014, v. 15, n. 3, p. 222, doi. 10.1038/ni.2835

By:

Fehervari, Zoltan

Publication type:

Article

RECENT PROGRESS IN DEVELOPING SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS AS POTENTIAL EFFECTIVE ANTICANCER AGENTS: REVIEW.

Published in:

Karbala Journal of Pharmaceutical Sciences, 2021, v. 1, n. 19, p. 28

By:

Alwash, Ameer H.;
Alani, Baraa G.;
Ibrahim, Ismail T.

Publication type:

Article

Inhibition of HDAC8 and HDAC9 by microbial short-chain fatty acids breaks immune tolerance of the epidermis to TLR ligands.

Published in:

Science Immunology, 2016, v. 1, n. 4, p. 1, doi. 10.1126/sciimmunol.aah4609

By:

Sanford, James A.;
Ling-Juan Zhang;
Williams, Michael R.;
Gangoiti, Jon A.;
Chun-Ming Huang;
Gallo, Richard L.

Publication type:

Article

HDAC Inhibitors Restore the Capacity of Aged Mice to Respond to Haloperidol through Modulation of Histone Acetylation.

Published in:

Neuropsychopharmacology, 2014, v. 39, n. 6, p. 1469, doi. 10.1038/npp.2013.346

By:

Montalvo-Ortiz, Janitza L;
Keegan, Jack;
Gallardo, Christopher;
Gerst, Nicolas;
Tetsuka, Kazuhiro;
Tucker, Chris;
Matsumoto, Mitsuyuki;
Fang, Deyu;
Csernansky, John G;
Dong, Hongxin

Publication type:

Article

Antidepressant-Like Properties of Novel HDAC6-Selective Inhibitors with Improved Brain Bioavailability.

Published in:

Neuropsychopharmacology, 2014, v. 39, n. 2, p. 389, doi. 10.1038/npp.2013.207

By:

Jochems, Jeanine;
Boulden, Janette;
Lee, Bridgin G;
Blendy, Julie A;
Jarpe, Matthew;
Mazitschek, Ralph;
Van Duzer, John H;
Jones, Simon;
Berton, Olivier

Publication type:

Article

Exercise and Sodium Butyrate Transform a Subthreshold Learning Event into Long-Term Memory via a Brain-Derived Neurotrophic factor-Dependent Mechanism.

Published in:

Neuropsychopharmacology, 2013, v. 38, n. 10, p. 2027, doi. 10.1038/npp.2013.104

By:

Intlekofer, Karlie A;
Berchtold, Nicole C;
Malvaez, Melissa;
Carlos, Anthony J;
McQuown, Susan C;
Cunningham, Michael J;
Wood, Marcelo A;
Cotman, Carl W

Publication type:

Article

Hyposensitivity to Gamma-Aminobutyric Acid in the Ventral Tegmental Area During Alcohol Withdrawal: Reversal by Histone Deacetylase Inhibitors.

Published in:

Neuropsychopharmacology, 2013, v. 38, n. 9, p. 1674, doi. 10.1038/npp.2013.65

By:

Arora, Devinder S;
Nimitvilai, Sudarat;
Teppen, Tara L;
McElvain, Maureen A;
Sakharkar, Amul J;
You, Chang;
Pandey, Subhash C;
Brodie, Mark S

Publication type:

Article

A PHD12-Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transition.

Published in:

Journal of Cell Biology, 2012, v. 198, n. 6, p. 999, doi. 10.1083/jcb.201203098

By:

Strobl-Mazzulla, Pablo H.;
Bronner, Marianne E.

Publication type:

Article

High-Throughput Screening for Epigenetic Compounds That Induce Human β-Defensin 1 Synthesis.

Published in:

Antibiotics (2079-6382), 2023, v. 12, n. 2, p. 186, doi. 10.3390/antibiotics12020186

By:

Lyu, Wentao;
Deng, Zhuo;
Zhang, Guolong

Publication type:

Article

Augmentation of Cationic Antimicrobial Peptide Production with Histone Deacetylase Inhibitors as a Novel Epigenetic Therapy for Bacterial Infections.

Published in:

Antibiotics (2079-6382), 2015, v. 4, n. 1, p. 44, doi. 10.3390/antibiotics4010044

By:

Yedery, Roshan D.;
Jerse, Ann E.

Publication type:

Article

Salvage camrelizumab for an intractable NK/T cell lymphoma patient with two instances of intestinal perforation: a case report and literature review.

Published in:

European Review for Medical & Pharmacological Sciences, 2023, v. 27, n. 10, p. 4570

By:

XIA, Y.;
LI, Q.-H.;
LIU, T.;
LIU, X.-X.;
PAN, H.-X.;
ZHANG, L.-L.;
ZHU, F.

Publication type:

Article

The inhibitory effects of class I histone deacetylases on hippocampal neuroinflammatory regulation in aging mice with postoperative cognitive dysfunction.

Published in:

European Review for Medical & Pharmacological Sciences, 2020, v. 24, n. 19, p. 10194

By:

YANG, C.-X.;
BAO, F.;
ZHONG, J.;
ZHANG, L.;
DENG, L.-B.;
SHA, Q.;
JIANG, H.

Publication type:

Article

Trichostatin A alleviates the process of breast carcinoma by downregulating LPAR5.

Published in:

European Review for Medical & Pharmacological Sciences, 2020, v. 24, n. 11, p. 6417

By:

ZHENG, Y.-Q.;
MIAO, X.;
LI, J.;
HU, M.-F.;
ZHU, Y.-S.;
LI, X.-R.;
ZHANG, Y.-J.

Publication type:

Article

Valproic acid as a radio-sensitizer in glioma: A systematic review and meta-analysis.

Published in:

Neuro-Oncology Practice, 2023, v. 10, n. 1, p. 13, doi. 10.1093/nop/npac078

By:

Sullivan, Jessica K;
Fahey, Paul P;
Agho, Kinglsey E;
Hurley, Simon P;
Feng, Zhihui;
Day, Richard O;
Lim, David

Publication type:

Article

Radiosensitizers in the temozolomide era for newly diagnosed glioblastoma.

Published in:

Neuro-Oncology Practice, 2020, v. 7, n. 3, p. 268, doi. 10.1093/nop/npz057

By:

Mathen, Peter;
Rowe, Lindsay;
Mackey, Megan;
Smart, DeeDee;
Tofilon, Philip;
Camphausen, Kevin

Publication type:

Article

Late toxicity in long-term survivors from a phase 2 study of concurrent radiation therapy, temozolomide and valproic acid for newly diagnosed glioblastoma.

Published in:

Neuro-Oncology Practice, 2018, v. 5, n. 4, p. 246, doi. 10.1093/nop/npy009

By:

Krauze, Andra V;
Mackey, Megan;
Rowe, Lindsay;
Chang, Michal G;
Holdford, Diane J;
Cooley, Theresa;
Shih, Joanna;
Tofilon, Philip J;
Camphausen, Kevin

Publication type:

Article

Targeting HDAC enzymes by SAHA enhances the cytotoxic effects of cisplatin on acute myeloid leukemia cells.

Published in:

Journal of Experimental & Clinical Medicine / Deneysel ve Klinik Tip Dergisi, 2024, v. 41, n. 3, p. 524, doi. 10.52142/omujecm.41.3.14

By:

ŞANSAÇAR, Merve;
PEKİN, Özge;
GENCER AKÇOK, Emel Başak

Publication type:

Article

Green synthesized silver nanoparticles using Rhazya stricta extract for delivery of HDAC inhibitor panobinostat in MDAMB-231 breast cancer cell line.

Published in:

Nanomedicine Journal, 2024, v. 11, n. 2, p. 187, doi. 10.22038/NMJ.2024.75733.1839

By:

Nawaz, Tayyaba;
Shehzad, Adeeb;
Miran, Waheed;
Nadeem, Aroosa Younis;
Nawaz, Tooba

Publication type:

Article

Histone Deacetylase (HDAC) Inhibitors as a Novel Therapeutic Option Against Fibrotic and Inflammatory Diseases.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 12, p. 1605, doi. 10.3390/biom14121605

By:

Theodoropoulou, Maria A.;
Mantzourani, Christiana;
Kokotos, George

Publication type:

Article

Combined Pharmacological Modulation of Translational and Transcriptional Activity Signaling Pathways as a Promising Therapeutic Approach in Children with Myocardial Changes.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 4, p. 477, doi. 10.3390/biom14040477

By:

Kamenshchyk, Andrii;
Belenichev, Igor;
Oksenych, Valentyn;
Kamyshnyi, Oleksandr

Publication type:

Article

Efficacy of HDAC Inhibitors in Driving Peroxisomal β-Oxidation and Immune Responses in Human Macrophages: Implications for Neuroinflammatory Disorders.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 12, p. 1696, doi. 10.3390/biom13121696

By:

Villoria-González, Andrea;
Zierfuss, Bettina;
Parzer, Patricia;
Heuböck, Elisabeth;
Zujovic, Violetta;
Waidhofer-Söllner, Petra;
Ponleitner, Markus;
Rommer, Paulus;
Göpfert, Jens;
Forss-Petter, Sonja;
Berger, Johannes;
Weinhofer, Isabelle

Publication type:

Article

Biological Effects of HDAC Inhibitors Vary with Zinc Binding Group: Differential Effects on Zinc Bioavailability, ROS Production, and R175H p53 Mutant Protein Reactivation.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 11, p. 1588, doi. 10.3390/biom13111588

By:

Flores, Brianna M.;
Uppalapati, Chandana K.;
Pascual, Agnes S.;
Vong, Alan;
Baatz, Margaux A.;
Harrison, Alisha M.;
Leyva, Kathryn J.;
Hull, Elizabeth E.

Publication type:

Article

Revisiting Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients with Glioblastoma—Proteomic Alteration and Comparison Analysis with the Standard-of-Care Chemoirradiation.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 10, p. 1499, doi. 10.3390/biom13101499

By:

Krauze, Andra V.;
Zhao, Yingdong;
Li, Ming-Chung;
Shih, Joanna;
Jiang, Will;
Tasci, Erdal;
Cooley Zgela, Theresa;
Sproull, Mary;
Mackey, Megan;
Shankavaram, Uma;
Tofilon, Philip;
Camphausen, Kevin

Publication type:

Article

Low-Dose Chidamide Treatment Displays Sex-Specific Differences in the 3xTg-AD Mouse.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 9, p. 1324, doi. 10.3390/biom13091324

By:

Dennison, Jessica;
Mendez, Armando;
Szeto, Angela;
Lohse, Ines;
Wahlestedt, Claes;
Volmar, Claude-Henry

Publication type:

Article

The Effects of Natural Epigenetic Therapies in 3D Ovarian Cancer and Patient-Derived Tumor Explants: New Avenues in Regulating the Cancer Secretome.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 7, p. 1066, doi. 10.3390/biom13071066

By:

Kelly, Rebeca;
Aviles, Diego;
Krisulevicz, Catriona;
Hunter, Krystal;
Krill, Lauren;
Warshal, David;
Ostrovsky, Olga

Publication type:

Article

Inherited Retinal Degeneration: Towards the Development of a Combination Therapy Targeting Histone Deacetylase, Poly (ADP-Ribose) Polymerase, and Calpain.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 4, p. 581, doi. 10.3390/biom13040581

By:

Dong, Yujie;
Yan, Jie;
Yang, Ming;
Xu, Wenrong;
Hu, Zhulin;
Paquet-Durand, François;
Jiao, Kangwei

Publication type:

Article

Targeted Epigenetic Interventions in Cancer with an Emphasis on Pediatric Malignancies.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 1, p. 61, doi. 10.3390/biom13010061

By:

Gaál, Zsuzsanna

Publication type:

Article

Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor.

Published in:

Clinical & Translational Medicine, 2024, v. 14, n. 6, p. 1, doi. 10.1002/ctm2.1691

By:

Shi, Zi‐Yang;
Fang, Ying;
Xu, Peng‐Peng;
Yi, Hong‐Mei;
Li, Jian‐Feng;
Dong, Yan;
Zhu, Yue;
Liu, Meng‐Ke;
Fu, Di;
Wang, Shuo;
Shi, Qing;
Shen, Rong;
Zhong, Hui‐Juan;
Wang, Chao‐Fu;
Cheng, Shu;
Wang, Li;
Liu, Feng;
Zhao, Wei‐Li

Publication type:

Article

Single‐cell profiling guided combination therapy of c‐Fos and histone deacetylase inhibitors in diffuse large B‐cell lymphoma.

Published in:

Clinical & Translational Medicine, 2022, v. 12, n. 5, p. 1, doi. 10.1002/ctm2.858

By:

Krämer, Oliver H.;
Schneider, Günter

Publication type:

Article

Single‐cell profiling‐guided combination therapy of c‐Fos and histone deacetylase inhibitors in diffuse large B‐cell lymphoma.

Published in:

Clinical & Translational Medicine, 2022, v. 12, n. 5, p. 1, doi. 10.1002/ctm2.798

By:

Wang, Luqiao;
Wu, Zijuan;
Xia, Yi;
Lu, Xueying;
Li, Ji;
Fan, Lei;
Qiao, Chun;
Qiu, Hairong;
Gu, Danling;
Xu, Wei;
Li, Jianyong;
Jin, Hui

Publication type:

Article

Editorial: Reviews in radiation oncology.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1283431

By:

Lee, David Y.;
Sudhandiran, Ganapasam;
Sharma, Sunil D.

Publication type:

Article

A review of the therapeutic potential of histone deacetylase inhibitors in rhabdomyosarcoma.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1244035

By:

Selim, Omar;
Song, Clara;
Kumar, Amy;
Phelan, Rebecca;
Singh, Arun;
Federman, Noah

Publication type:

Article

HDAC-an important target for improving tumor radiotherapy resistance.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1193637

By:

Rui Ling;
Jingzhi Wang;
Yuan Fang;
Yunpeng Yu;
Yuting Su;
Wen Sun;
Xiaoqin Li;
Xiang Tang

Publication type:

Article

Efficacy and safety of histone deacetylase inhibitors in peripheral T-cell lymphoma: a systematic review and meta-analysis on prospective clinical trials.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1127112

By:

Peipei Yang;
Ailin Zhao;
Kai Shen;
He Li;
Jinjin Wang;
Hui Zhou;
Zhongwang Wang;
Mengyao Wang;
Ying Qu;
Li Zhang;
Yuhuan Zheng;
Ting Niu

Publication type:

Article

Precise diagnosis and targeted therapy of nodal T-follicular helper cell lymphoma (T-FHCL).

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1163190

By:

Jun Du;
Shikai Jin;
Minghui Zhang;
Xuehang Fu;
Jingwen Yang;
Liwen Zhang;
Zhenwei Chen;
Zoufang Huang;
Weisong Li;
Jian Hou;
Ting Wang

Publication type:

Article

HDAC inhibitors enhance the anti-tumor effect of immunotherapies in hepatocellular carcinoma.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1170207

By:

Chen Shen;
Mei Li;
Yujuan Duan;
Xin Jiang;
Xiaoming Hou;
Fulai Xue;
Yinan Zhang;
Yao Luo

Publication type:

Article

Inhibition of histone deacetylases attenuates tumor progression and improves immunotherapy in breast cancer.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1164514

By:

Bi Lian;
Xiaosong Chen;
Kunwei Shen

Publication type:

Article

HDAC inhibitors Panobinostat and Romidepsin enhance tax transcription in HTLV-1-infected cell lines and freshly isolated patients' T-cells.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.978800

By:

Schnell, Annika P.;
Kohrt, Stephan;
Aristodemou, Aris;
Taylor, Graham P.;
Bangham, Charles R. M.;
Thoma-Kress, Andrea K.

Publication type:

Article

Hepatic Tumor Stiffness Measured by Shear Wave Elastography Is Prognostic for HCC Progression Following Treatment With Anti-PD-1 Antibodies Plus Lenvatinib: A Retrospective Analysis of Two Independent Cohorts.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.868809

By:

Yuan, Guosheng;
Xie, Fuli;
Song, Yangda;
Li, Qi;
Li, Rong;
Hu, Xiaoyun;
Zang, Mengya;
Cheng, Xiao;
Lu, Guanting;
Huang, Jing;
Fan, Wenzhe;
Rong, Xiaoxiang;
Sun, Jian;
Chen, Jinzhang

Publication type:

Article

Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice.

Published in:

Diabetes, Obesity & Metabolism, 2017, v. 19, n. 7, p. 936, doi. 10.1111/dom.12896

By:

Gaur, Vidhi;
Connor, Timothy;
Venardos, Kylie;
Henstridge, Darren C.;
Martin, Sheree D.;
Swinton, Courtney;
Morrison, Shona;
Aston‐Mourney, Kathryn;
Gehrig, Stefan M.;
van Ewijk, Roelof;
Lynch, Gordon S.;
Febbraio, Mark A.;
Steinberg, Gregory R.;
Hargreaves, Mark;
Walder, Ken R.;
McGee, Sean L.

Publication type:

Article

Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats.

Published in:

Diabetes, Obesity & Metabolism, 2015, v. 17, n. 7, p. 703, doi. 10.1111/dom.12470

By:

Lundh, M.;
Galbo, T.;
Poulsen, S. S.;
Mandrup‐Poulsen, T.

Publication type:

Article

Effects of combination therapy with dipeptidyl peptidase- IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes.

Published in:

Clinical & Experimental Immunology, 2013, v. 172, n. 3, p. 375, doi. 10.1111/cei.12068

By:

Cabrera, S. M.;
Colvin, S. C.;
Tersey, S. A.;
Maier, B.;
Nadler, J. L.;
Mirmira, R. G.

Publication type:

Article

Heliomycin and tetracinomycin D: anthraquinone derivatives with histone deacetylase inhibitory activity from marine sponge-associated Streptomyces sp. SP9.

Published in:

3 Biotech, 2018, v. 8, n. 6, p. 1, doi. 10.1007/s13205-018-1304-1

By:

Abdelfattah, Mohamed Saleh;
Elmallah, Mohammed Ismail Youssef;
Faraag, Ahmed Hassan Ibrahim;
Hebishy, Ali Mohamed Salah;
Ali, Neama Hassan

Publication type:

Article

Arsenite induces dysfunction of regulatory T cells through acetylation control of the Foxp3 promoter.

Published in:

Human & Experimental Toxicology, 2021, v. 40, n. 1, p. 35, doi. 10.1177/0960327120934533

By:

Chen, J;
Jiang, J;
Liu, Y;
Ye, Y;
Ma, Y;
Cen, Y;
Chen, W;
Wang, S;
Yang, G;
Zhang, A

Publication type:

Article