Works matching Selkoe, Dennis J.
Results: 179
Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-β1 in the CNS.
- Published in:
- Glia, 2013, v. 61, n. 6, p. 985, doi. 10.1002/glia.22490
- By:
- Publication type:
- Article
Amyloid-lowering isocoumarins are not direct inhibitors of γ-secretase.
- Published in:
- Nature Cell Biology, 2002, v. 4, n. 5, p. E110, doi. 10.1038/ncb0502-e110b
- By:
- Publication type:
- Article
Transition-state analogue inhibitors of γ-secretase bind directly to presenilin-1.
- Published in:
- Nature Cell Biology, 2000, v. 2, n. 7, p. 428, doi. 10.1038/35017062
- By:
- Publication type:
- Article
Plasma beta-amyloid level, cognitive reserve, and cognitive decline.
- Published in:
- 2011
- By:
- Publication type:
- commentary
Plasma β-Amyloid Level, Cognitive Reserve, and Cognitive Decline.
- Published in:
- 2011
- By:
- Publication type:
- Letter
Imaging Alzheimer's amyloid.
- Published in:
- Nature Biotechnology, 2000, v. 18, n. 8, p. 823, doi. 10.1038/78422
- By:
- Publication type:
- Article
Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate.
- Published in:
- Journal of Neuroscience, 2017, v. 37, n. 1, p. 152, doi. 10.1523/JNEUROSCI.1698-16.2017
- By:
- Publication type:
- Article
C-Terminally Truncated Forms of Tau, But Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell Death.
- Published in:
- Journal of Neuroscience, 2015, v. 35, n. 30, p. 10851, doi. 10.1523/JNEUROSCI.0387-15.2015
- By:
- Publication type:
- Article
A de novo designed helix-turn-helix peptide forms nontoxic amyloid fibrils.
- Published in:
- Nature Structural Biology, 2000, v. 7, n. 12, p. 1095, doi. 10.1038/81937
- By:
- Publication type:
- Article
Aspartate Mutations in Presenilin and γ-Secretase Inhibitors Both Impair Notch1 Proteolysis and Nuclear Translocation with Relative Preservation of Notch1 Signaling.
- Published in:
- Journal of Neurochemistry, 2000, v. 75, n. 2, p. 583, doi. 10.1046/j.1471-4159.2000.0750583.x
- By:
- Publication type:
- Article
Caffeine Stimulates Amyloid β-Peptide Release from β-Amyloid Precursor Protein-Transfected HEK293 Cells.
- Published in:
- Journal of Neurochemistry, 1997, v. 69, n. 4, p. 1580, doi. 10.1046/j.1471-4159.1997.69041580.x
- By:
- Publication type:
- Article
Association of SNCA with Parkinson: Replication in the Harvard NeuroDiscovery Center Biomarker Study.
- Published in:
- Movement Disorders, 2011, v. 26, n. 12, p. 2283, doi. 10.1002/mds.23934
- By:
- Publication type:
- Article
?-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation.
- Published in:
- Nature, 2011, v. 477, n. 7362, p. 107, doi. 10.1038/nature10324
- By:
- Publication type:
- Article
Structural biology: Enzyme target to latch on to.
- Published in:
- Nature, 2006, v. 443, n. 7113, p. 761, doi. 10.1038/nature05210
- By:
- Publication type:
- Article
A Mathematical Model of the Impact of Novel Treatments on the A<b>β</b>Burden in the Alzheimer’s Brain, CSF and Plasma
- Published in:
- Bulletin of Mathematical Biology, 2002, v. 64, n. 5, p. 1011, doi. 10.1006/bulm.2002.0304
- By:
- Publication type:
- Article
A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursor.
- Published in:
- Journal of Cell Biology, 2019, v. 218, n. 2, p. 644, doi. 10.1083/jcb.201806205
- By:
- Publication type:
- Article
Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis.
- Published in:
- Journal of Cell Biology, 2015, v. 211, n. 6, p. 1157, doi. 10.1083/jcb.201502001
- By:
- Publication type:
- Article
Lecanemab and Vascular-Amyloid Deposition in Brains of People With Down Syndrome.
- Published in:
- JAMA Neurology, 2024, v. 81, n. 10, p. 1066, doi. 10.1001/jamaneurol.2024.2579
- By:
- Publication type:
- Article
Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease: Two Phase 3 Randomized Placebo-Controlled Trials.
- Published in:
- JAMA Neurology, 2022, v. 79, n. 11, p. 1113, doi. 10.1001/jamaneurol.2022.2909
- By:
- Publication type:
- Article
Unfairness to Patients With Alzheimer Disease in Medicare's Coverage of Antiamyloid Immunotherapy.
- Published in:
- 2022
- By:
- Publication type:
- Opinion
The Origins of Alzheimer Disease.
- Published in:
- 2000
- By:
- Publication type:
- Editorial
Munchausen Syndrome--SLE.
- Published in:
- 1970
- By:
- Publication type:
- Letter
miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer's Patients.
- Published in:
- Frontiers in Neuroscience, 2019, v. 13, p. 1, doi. 10.3389/fnins.2019.01208
- By:
- Publication type:
- Article
Isolation of Low-Molecular-Weight Proteins from Amyloid Plaque Fibers in Alzheimer's Disease.
- Published in:
- Journal of Neurochemistry, 1986, v. 46, n. 6, p. 1820, doi. 10.1111/j.1471-4159.1986.tb08501.x
- By:
- Publication type:
- Article
Characterization of Postmortem Human Brain Proteins by Two-Dimensional Gel Electrophoresis.
- Published in:
- Journal of Neurochemistry, 1982, v. 39, n. 6, p. 1529, doi. 10.1111/j.1471-4159.1982.tb07985.x
- By:
- Publication type:
- Article
Normal Cellular Processing of the β-Amyloid Precursor Protein Results in the Secretion of the Amyloid β Peptide and Related Molecules.
- Published in:
- Annals of the New York Academy of Sciences, 1993, v. 695, n. 1, p. 109, doi. 10.1111/j.1749-6632.1993.tb23037.x
- By:
- Publication type:
- Article
Bartels & Selkoe reply.
- Published in:
- Nature, 2013, v. 498, n. 7453, p. E6, doi. 10.1038/nature12126
- By:
- Publication type:
- Article
Performance characteristics of plasma amyloid-beta 40 and 42 assays.
- Published in:
- 2009
- By:
- Publication type:
- journal article
Performance Characteristics of Plasma Amyloid-β 40 and 42 Assays.
- Published in:
- Journal of Alzheimer's Disease, 2009, v. 16, n. 2, p. 277, doi. 10.3233/JAD-2009-0948
- By:
- Publication type:
- Article
Amyloid β-peptide is produced by cultured cells during normal metabolism: A reprise.
- Published in:
- Journal of Alzheimer's Disease, 2006, v. 9, n. 3, p. 163, doi. 10.3233/JAD-2006-9S319
- By:
- Publication type:
- Article
Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1.
- Published in:
- Human Molecular Genetics, 2008, v. 17, n. 4, p. 602, doi. 10.1093/hmg/ddm334
- By:
- Publication type:
- Article
Dynamics of plasma biomarkers in Down syndrome: the relative levels of Aβ42 decrease with age, whereas NT1 tau and NfL increase.
- Published in:
- Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13195-020-00593-7
- By:
- Publication type:
- Article
Palmitoylation of the Parkinson's disease–associated protein synaptotagmin-11 links its turnover to α-synuclein homeostasis.
- Published in:
- Science Signaling, 2023, v. 16, n. 772, p. 1, doi. 10.1126/scisignal.add7220
- By:
- Publication type:
- Article
Alzheimer disease: mechanistic understanding predicts novel therapies.
- Published in:
- 2004
- By:
- Publication type:
- journal article
Alzheimer Disease: Mechanistic Understanding Predicts Novel Therapies.
- Published in:
- Annals of Internal Medicine, 2004, v. 140, n. 8, p. 627, doi. 10.7326/0003-4819-140-8-200404200-00047
- By:
- Publication type:
- Article
Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation.
- Published in:
- Molecular Neurodegeneration, 2011, v. 6, n. 1, p. 10, doi. 10.1186/1750-1326-6-10
- By:
- Publication type:
- Article
α-Synuclein Neuropathology is Controlled by Nuclear Hormone Receptors and Enhanced by Docosahexaenoic Acid in A Mouse Model for Parkinson's Disease.
- Published in:
- Brain Pathology, 2012, v. 22, n. 3, p. 280, doi. 10.1111/j.1750-3639.2011.00530.x
- By:
- Publication type:
- Article
Studies on the Relationship between Plasma Proteins and Amyloid Fibrils Found in Alzheimer's Disease.
- Published in:
- Annals of the New York Academy of Sciences, 1988, v. 529, n. 1, p. 233, doi. 10.1111/j.1749-6632.1988.tb51468.x
- By:
- Publication type:
- Article
HPLC Analysis of Proteins from Alzheimer Paired Helical Filaments.
- Published in:
- Annals of the New York Academy of Sciences, 1987, v. 494, n. 1, p. 369, doi. 10.1111/j.1749-6632.1987.tb29575.x
- By:
- Publication type:
- Article
Proteomic Profiling of γ-Secretase Substrates and Mapping of Substrate Requirements.
- Published in:
- PLoS Biology, 2008, v. 6, n. 10, p. 2314, doi. 10.1371/journal.pbio.0060257
- By:
- Publication type:
- Article
Amyloid precursor on the Go.
- Published in:
- Nature, 1993, v. 362, n. 6415, p. 14, doi. 10.1038/362014a0
- By:
- Publication type:
- Article
Parkinson-causing mutations in LRRK2 impair the physiological tetramerization of endogenous α-synuclein in human neurons.
- Published in:
- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00380-1
- By:
- Publication type:
- Article
The Deposition of Amyloid Proteins in the Aging Mammalian Brain: Implications for Alzheimer's Disease.
- Published in:
- Annals of Medicine, 1989, v. 21, n. 2, p. 73, doi. 10.3109/07853898909149187
- By:
- Publication type:
- Article
A Stearoyl–Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α‐Synuclein Mice.
- Published in:
- Annals of Neurology, 2021, v. 89, n. 1, p. 74, doi. 10.1002/ana.25920
- By:
- Publication type:
- Article
Target engagement in an alzheimer trial: Crenezumab lowers amyloid β oligomers in cerebrospinal fluid.
- Published in:
- 2019
- By:
- Publication type:
- journal article
The therapeutics of Alzheimer's disease: Where we stand and where we are heading.
- Published in:
- Annals of Neurology, 2013, v. 74, n. 3, p. 328, doi. 10.1002/ana.24001
- By:
- Publication type:
- Article
The relation between insulin, insulin-related factors, and plasma amyloid-beta protein levels at mid-life in a large-scale population-based study
- Published in:
- 2010
- By:
- Publication type:
- Abstract
ADF/cofilin-actin rods and synaptic loss in Alzheimer's disease
- Published in:
- 2010
- By:
- Publication type:
- Abstract
P4-209: Direct and potent regulation of γ-secretase by its lipid microenvironment
- Published in:
- 2008
- By:
- Publication type:
- Abstract
P3-415: The presence of Abeta dimers in soluble brain extract is associated with dementia
- Published in:
- 2008
- By:
- Publication type:
- Abstract