Works matching DE "MIDAZOLAM"

Results: 2915

Extrapolation of Midazolam Disposition in Neonates Using Physiological‐Based Pharmacokinetic/Pharmacodynamic Modeling.

Published in:

Clinical Pharmacology in Drug Development, 2025, v. 14, n. 6, p. 415, doi. 10.1002/cpdd.1531

By:

Zhao, Tangping;
Lv, Zhanhui;
Zhou, Sufeng;
Wang, Lu;
Li, Tongtong;
Zhu, Jinying;
Shao, Feng

Publication type:

Article

It's All About the Bubbles: Assessing the Effects of Simethicone on Safety and Efficacy During Colonoscopy.

Published in:

Digestive Diseases & Sciences, 2025, v. 70, n. 5, p. 1832, doi. 10.1007/s10620-025-08938-8

By:

Perrin, Michael A.;
Nguyen Wenker, Theresa H.;
Larson, Scott A.

Publication type:

Article

Exploring Conscious Sedation in Pediatric Oral Surgery: A Non-Randomized Clinical Trial on Safety and Efficacy.

Published in:

Children, 2025, v. 12, n. 5, p. 604, doi. 10.3390/children12050604

By:

Cenzato, Niccolò;
Pasquali, Lorenzo;
Menozzi, Gregorio;
Maspero, Cinzia

Publication type:

Article

Ketamine for unipolar major depression: critical examination of antidepressant effects.

Published in:

BJPsych Advances, 2025, v. 31, n. 3, p. 131, doi. 10.1192/bja.2024.84

By:

Patel, Aditya

Publication type:

Article

Frequency and predictors of palliative sedation among patients with cancer who died in a specialist inpatient palliative care unit: a retrospective study.

Published in:

BMC Palliative Care, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12904-025-01787-2

By:

Torres-Tenor, Juan Luis;
Villalba-Cuesta, Paula;
Bruera, Eduardo;
Vilches-Aguirre, Yolanda;
Varela-Cerdeira, María;
Alonso-Babarro, Alberto

Publication type:

Article

Penile Strangulation by Metallic Rings.

Published in:

Indian Journal of Surgery, 2011, v. 73, n. 5, p. 359, doi. 10.1007/s12262-011-0329-z

By:

Farooqui, Mohammad;
Meena, R.

Publication type:

Article

Remifentanil-assisted local anaesthesia: Application to continence surgery.

Published in:

Australian & New Zealand Journal of Obstetrics & Gynaecology, 2008, v. 48, n. 2, p. 214, doi. 10.1111/j.1479-828X.2008.00837.x

By:

Haylen, Bernard T.;
Katz, Steven;
Chetty, Naven

Publication type:

Article

Intranasal Fentanyl Combined with Oral Midazolam for Pediatric Dental Sedation: A Controlled Randomized Blinded Crossover Clinical Trial.

Published in:

Pediatric Dentistry, 2022, v. 44, n. 4, p. 255

By:

Alhaidari, Roaa I.;
AlSarheed, Maha;
Sheta, Saad A.;
Aldhubaiban, Mohammed

Publication type:

Article

Does pre-sedation with midazolam versus clonidine decrease post-operative negative behavior in young children?

Published in:: 2022
Publication type:: Abstract

Effectiveness of Intranasal Dexmedetomidine with Nitrous Oxide Compared to Other Pediatric Dental Sedation Drug Regimens.

Published in:

Pediatric Dentistry, 2021, v. 43, n. 6, p. 457

By:

Unkel, John H.;
Berry, Elizabeth J.;
Ko, Brittany L.;
Amarteifio, Victor;
Piscitelli, William;
Reinhartz, Dennis;
Reinhartz, Judy;
Warren II, Robert

Publication type:

Article

A Retrospective Study of Dosing Weight and Outcomes for One Pediatric Dental Sedation Regimen.

Published in:

Pediatric Dentistry, 2018, v. 40, n. 5, p. 346

By:

Olacke, Becky;
Nelson, Travis;
Sarvas, Elise;
Scott, JoAnna M.

Publication type:

Article

Comparison of Two Morphine-Benzodiazepine-Hydroxyzine Combinations for the Oral Sedation of Pediatric Dental Patients: A Retrospective Study.

Published in:

2018

By:

Chen, Norman;
Tanbonliong, Thomas

Publication type:

journal article

Midazolam anesthesia during rigid and flexible cystoscopy.

Published in:

Urological Research, 2007, v. 35, n. 3, p. 139, doi. 10.1007/s00240-007-0091-7

By:

Yun Seob Song;
Eun Seop Song;
Kong Jo Kim;
Young Ho Park;
Ja Hyeon Ku

Publication type:

Article

A novel physiologically-based pharmacokinetic model to estimate reduced CYP3A4 activity in cancer patients utilizing the neutrophil-to-lymphocyte ratio as an inflammatory marker.

Published in:

European Journal of Clinical Pharmacology, 2025, v. 81, n. 6, p. 853, doi. 10.1007/s00228-025-03839-1

By:

Coutant, David E.;
Rehmel, Jessica;
Edwards, Donna M.;
Hall, Stephen D.

Publication type:

Article

Oral bioavailability of microdoses and therapeutic doses of midazolam as a 2-dimensionally printed orodispersible film in healthy volunteers.

Published in:

European Journal of Clinical Pharmacology, 2022, v. 78, n. 12, p. 1965, doi. 10.1007/s00228-022-03406-y

By:

Breithaupt, Mareile H.;
Krohmer, Evelyn;
Taylor, Lenka;
Koerner, Eva;
Hoppe-Tichy, Torsten;
Burhenne, Juergen;
Foerster, Kathrin I.;
Dachtler, Markus;
Huber, Gerald;
Venkatesh, Rakesh;
Eggenreich, Karin;
Czock, David;
Mikus, Gerd;
Blank, Antje;
Haefeli, Walter E.

Publication type:

Article

Response to: "Utility of endogenous 4β-hydroxycholesterol as a biomarker to assess cytochrome P 450 3A (CYP3A) activity: not quite ready for prime time".

Published in:

2022

By:

Kvitne, Kine Eide;
Hole, Kristine;
Molden, Espen;
Robertsen, Ida

Publication type:

Letter

Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range.

Published in:

European Journal of Clinical Pharmacology, 2022, v. 78, n. 8, p. 1289, doi. 10.1007/s00228-022-03336-9

By:

Eide Kvitne, Kine;
Hole, Kristine;
Krogstad, Veronica;
Wollmann, Birgit Malene;
Wegler, Christine;
Johnson, Line K.;
Hertel, Jens K.;
Artursson, Per;
Karlsson, Cecilia;
Andersson, Shalini;
Andersson, Tommy B.;
Sandbu, Rune;
Hjelmesæth, Jøran;
Skovlund, Eva;
Christensen, Hege;
Jansson-Löfmark, Rasmus;
Åsberg, Anders;
Molden, Espen;
Robertsen, Ida

Publication type:

Article

Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans.

Published in:

European Journal of Clinical Pharmacology, 2022, v. 78, n. 6, p. 975, doi. 10.1007/s00228-022-03304-3

By:

Elbe, Annika;
Foerster, Kathrin Isabelle;
Blank, Antje;
Rose, Peter;
Burhenne, Jürgen;
Haefeli, Walter Emil;
Mikus, Gerd

Publication type:

Article

Evaluation of drug-drug interaction of lusutrombopag, a thrombopoietin receptor agonist, via metabolic enzymes and transporters.

Published in:

European Journal of Clinical Pharmacology, 2020, v. 76, n. 12, p. 1659, doi. 10.1007/s00228-020-02960-7

By:

Katsube, Takayuki;
Inoue, Yuji;
Fukuhara, Takahiro;
Kano, Takeshi;
Wajima, Toshihiro

Publication type:

Article

Safety, pharmacokinetic and pharmacodynamic properties of single ascending dose and continuous infusion of remimazolam besylate in healthy Chinese volunteers.

Published in:

European Journal of Clinical Pharmacology, 2020, v. 76, n. 3, p. 383, doi. 10.1007/s00228-019-02800-3

By:

Sheng, Xiao-yan;
Liang, Yan;
Yang, Xue-yuan;
Li, Li-e;
Ye, Xia;
Zhao, Xia;
Cui, Yi-min

Publication type:

Article

Identification of the caffeine to trimethyluric acid ratio as a dietary biomarker to characterise variability in cytochrome P450 3A activity.

Published in:

European Journal of Clinical Pharmacology, 2019, v. 75, n. 9, p. 1211, doi. 10.1007/s00228-019-02682-5

By:

van Dyk, Madelé;
Miners, John O.;
Marshall, Jean-Claude;
Wood, Linda S.;
Hopkins, Ashley;
Sorich, Michael J.;
Rowland, Andrew

Publication type:

Article

Interaction potential of the dual orexin receptor antagonist ACT-541468 with CYP3A4 and food: results from two interaction studies.

Published in:

European Journal of Clinical Pharmacology, 2019, v. 75, n. 2, p. 195, doi. 10.1007/s00228-018-2559-5

By:

Boof, Marie-Laure;
Ufer, Mike;
Dingemanse, Jasper;
Alatrach, Abir

Publication type:

Article

Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries.

Published in:

European Journal of Clinical Pharmacology, 2018, v. 74, n. 7, p. 913, doi. 10.1007/s00228-018-2450-4

By:

van Dyk, Madelé;
Marshall, Jean-Claude;
Sorich, Michael J;
Wood, Linda S.;
Rowland, Andrew

Publication type:

Article

Effect of breviscapine on CYP3A metabolic activity in healthy volunteers.

Published in:

European Journal of Clinical Pharmacology, 2018, v. 74, n. 1, p. 37, doi. 10.1007/s00228-017-2346-8

By:

Zhou, Xuan;
Gao, Yang-yang;
Hu, Jian-yong;
Dong, Yu;
Zhang, Hai-zhu;
Lai, Yong

Publication type:

Article

A pharmacokinetic drug-drug interaction study between selexipag and midazolam, a CYP3A4 substrate, in healthy male subjects.

Published in:

European Journal of Clinical Pharmacology, 2017, v. 73, n. 9, p. 1121, doi. 10.1007/s00228-017-2282-7

By:

Juif, Pierre-Eric;
Boehler, Margaux;
Donazzolo, Yves;
Bruderer, Shirin;
Dingemanse, Jasper

Publication type:

Article

Pharmacokinetics of ginkgolides A, B and K after single and multiple intravenous infusions and their interactions with midazolam in healthy Chinese male subjects.

Published in:

European Journal of Clinical Pharmacology, 2017, v. 73, n. 5, p. 537, doi. 10.1007/s00228-017-2197-3

By:

Shao, Feng;
Zhang, Hongwen;
Xie, Lijun;
Chen, Juan;
Zhou, Sufeng;
Zhang, Jinsong;
Lv, Jinru;
Hao, Weiwen;
Ma, Yunsu;
Liu, Yun;
Ou, Ning;
Xiao, Wei

Publication type:

Article

A limited sampling strategy based on maximum a posteriori Bayesian estimation for a five-probe phenotyping cocktail.

Published in:

European Journal of Clinical Pharmacology, 2016, v. 72, n. 1, p. 39, doi. 10.1007/s00228-015-1953-5

By:

Nguyen, Thu;
Bénech, Henri;
Pruvost, Alain;
Lenuzza, Natacha

Publication type:

Article

Severe opioid withdrawal syndrome after a single dose of nalmefene.

Published in:

2015

By:

Donnerstag, Nadine;
Schneider, Tobias;
Lüthi, Adrian;
Taegtmeyer, Anne;
Raetz Bravo, Alexandra;
Mehlig, Annekathrin

Publication type:

Letter

Assessment of interaction potential of AZD2066 using in vitro metabolism tools, physiologically based pharmacokinetic modelling and in vivo cocktail data.

Published in:

European Journal of Clinical Pharmacology, 2014, v. 70, n. 2, p. 167, doi. 10.1007/s00228-013-1603-8

By:

Nordmark, Anna;
Andersson, Anita;
Baranczewski, Pawel;
Wanag, Ewa;
Ståhle, Lars

Publication type:

Article

Effects of vercirnon on the activity of CYP3A4, CYP2C19 and CYP2C8 enzymes and BCRP and OATP1B1 transporters using probe substrates.

Published in:

European Journal of Clinical Pharmacology, 2014, v. 70, n. 1, p. 37, doi. 10.1007/s00228-013-1592-7

By:

Haberer, Lynda;
McSherry, Iain;
Cargill, Anna;
McCarthy, Linda

Publication type:

Article

A randomised study of the effect of danoprevir/ritonavir or ritonavir on substrates of cytochrome P450 (CYP) 3A and 2C9 in chronic hepatitis C patients using a drug cocktail.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 11, p. 1939, doi. 10.1007/s00228-013-1556-y

By:

Morcos, Peter;
Chang, Linda;
Kulkarni, Rohit;
Giraudon, Mylene;
Shulman, Nancy;
Brennan, Barbara;
Smith, Patrick;
Tran, Jonathan

Publication type:

Article

Influence of chronic hepatitis C infection on cytochrome P450 3a4 activity using midazolam as an in vivo probe substrate.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 10, p. 1777, doi. 10.1007/s00228-013-1525-5

By:

Morcos, P.;
Moreira, S.;
Brennan, B.;
Blotner, S.;
Shulman, N.;
Smith, P.

Publication type:

Article

Concentration effect relationship of CYP3A inhibition by ritonavir in humans.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 10, p. 1795, doi. 10.1007/s00228-013-1530-8

By:

Eichbaum, Christine;
Cortese, Marianna;
Blank, Antje;
Burhenne, Jürgen;
Mikus, Gerd

Publication type:

Article

Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 10, p. 1785, doi. 10.1007/s00228-013-1529-1

By:

Markert, Christoph;
Hellwig, Regina;
Burhenne, Jürgen;
Hoffmann, Michael;
Weiss, Johanna;
Mikus, Gerd;
Haefeli, Walter

Publication type:

Article

Evaluation of limited sampling models for prediction of oral midazolam AUC for CYP3A phenotyping and drug interaction studies.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 5, p. 1127, doi. 10.1007/s00228-012-1437-9

By:

Mueller, Silke;
Drewelow, Bernd

Publication type:

Article

Rate of onset of inhibition of gut-wall and hepatic CYP3A by clarithromycin.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 3, p. 439, doi. 10.1007/s00228-012-1339-x

By:

Quinney, Sara;
Malireddy, Srikar;
Vuppalanchi, Raj;
Hamman, Mitchell;
Chalasani, Naga;
Gorski, J.;
Hall, Stephen

Publication type:

Article

Effect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 3, p. 507, doi. 10.1007/s00228-012-1388-1

By:

Fuchs, Ines;
Hafner-Blumenstiel, Verena;
Markert, Christoph;
Burhenne, Jürgen;
Weiss, Johanna;
Haefeli, Walter;
Mikus, Gerd

Publication type:

Article

Pharmacokinetic interactions of almorexant with midazolam and simvastatin, two CYP3A4 model substrates, in healthy male subjects.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 3, p. 523, doi. 10.1007/s00228-012-1403-6

By:

Hoch, Matthias;
Hoever, Petra;
Alessi, Federica;
Theodor, Rudolf;
Dingemanse, Jasper

Publication type:

Article

The effect of lersivirine, a next-generation NNRTI, on the pharmacokinetics of midazolam and oral contraceptives in healthy subjects.

Published in:

European Journal of Clinical Pharmacology, 2012, v. 68, n. 11, p. 1567, doi. 10.1007/s00228-012-1287-5

By:

Davis, John;
Langdon, Grant;
Layton, Gary;
Chong, Chew;
Ndongo, Marie-Noella;
Vourvahis, Manoli

Publication type:

Article

Effect of Ginkgo biloba special extract EGb 761® on human cytochrome P450 activity: a cocktail interaction study in healthy volunteers.

Published in:

European Journal of Clinical Pharmacology, 2012, v. 68, n. 5, p. 553, doi. 10.1007/s00228-011-1174-5

By:

Zadoyan, G.;
Rokitta, D.;
Klement, S.;
Dienel, A.;
Hoerr, R.;
Gramatté, T.;
Fuhr, U.

Publication type:

Article

Acute toxicity associated with the recreational use of the ketamine derivative methoxetamine.

Published in:

European Journal of Clinical Pharmacology, 2012, v. 68, n. 5, p. 853, doi. 10.1007/s00228-011-1199-9

By:

Wood, David;
Davies, Susannah;
Puchnarewicz, Malgorzata;
Johnston, Atholl;
Dargan, Paul

Publication type:

Article

Proposal of a new limited sampling strategy to predict CYP3A activity using a partial AUC of midazolam.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 11, p. 1137, doi. 10.1007/s00228-010-0878-2

By:

Katzenmaier, Stephanie;
Markert, Christoph;
Mikus, Gerd

Publication type:

Article

Effect of glycyrrhizin on the activity of CYP3A enzyme in humans.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 8, p. 805, doi. 10.1007/s00228-010-0814-5

By:

Tu, Jiang-Hua;
He, Yi-Jing;
Chen, Yao;
Fan, Lan;
Zhang, Wei;
Tan, Zhi-Rong;
Huang, Yuan-Fei;
Guo, Dong;
Hu, Dong-Li;
Wang, Dan;
Zhou, Hong-Hao

Publication type:

Article

In vitro-in vivo extrapolation of zolpidem as a perpetrator of metabolic interactions involving CYP3A.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 3, p. 275, doi. 10.1007/s00228-009-0760-2

By:

Polasek, Thomas;
Sadagopal, Janani;
Elliot, David;
Miners, John

Publication type:

Article

Ontogeny of midazolam glucuronidation in preterm infants.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 2, p. 165, doi. 10.1007/s00228-009-0741-5

By:

Wildt, Saskia;
Kearns, Greg;
Murry, Darryl;
Koren, Gideon;
Anker, John

Publication type:

Article

Eltrombopag, an oral thrombopoietin receptor agonist, has no impact on the pharmacokinetic profile of probe drugs for cytochrome P450 isoenzymes CYP3A4, CYP1A2, CYP2C9 and CYP2C19 in healthy men: a cocktail analysis.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 1, p. 67, doi. 10.1007/s00228-009-0716-6

By:

Jenkins, Julian;
Williams, Daphne;
Deng, Yanli;
Collins, David;
Kitchen, Valerie

Publication type:

Article

CYP3A4*1G genetic polymorphism influences CYP3A activity and response to fentanyl in Chinese gynecologic patients.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 1, p. 61, doi. 10.1007/s00228-009-0726-4

By:

Zhang, Wei;
Chang, Yan-Zi;
Kan, Quan-Cheng;
Zhang, Li-Rong;
Li, Zhi-Song;
Lu, Hui;
Wang, Zhong-Yu;
Chu, Qin-Jun;
Zhang, Jie

Publication type:

Article

No clinically relevant CYP3A induction after St. John’s wort with low hyperforin content in healthy volunteers.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 1, p. 81, doi. 10.1007/s00228-008-0554-y

By:

Mueller, Silke C.;
Majcher-Peszynska, Jolanta;
Mundkowski, Ralf G.;
Uehleke, Bernhard;
Klammt, Sebastian;
Sievers, Hartwig;
Lehnfeld, Romanus;
Frank, Bruno;
Thurow, Kerstin;
Kundt, Guenther;
Drewelow, Bernd

Publication type:

Article

Investigation of the in vivo activity of CYP3A in Brazilian volunteers: comparison of midazolam and omeprazole as drug markers.

Published in:

European Journal of Clinical Pharmacology, 2008, v. 64, n. 9, p. 901, doi. 10.1007/s00228-008-0510-x

By:

Rocha, Adriana;
Coelho, Eduardo B.;
Moussa, Soraia A. P.;
Lanchote, Vera L.

Publication type:

Article

Impact of the CYP3A5 genotype on midazolam pharmacokinetics and pharmacodynamics during intensive care sedation.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 12, p. 1129, doi. 10.1007/s00228-007-0365-6

By:

Fromm, Martin F.;
Schwilden, Helmut;
Bachmakov, Iouri;
König, Jörg;
Bremer, Frank;
Schüttler, Jürgen

Publication type:

Article