- Title
Production of teicoplanin by a mutant of Actinoplanes teicomyceticus.
- Authors
Jae-Chan Lee; Hae-Ryong Park; Dong-Jin Park; Kwang Hee Son; Ki-Hong Yoon; Young-Bae Kim; Chang-Jin Kim
- Abstract
Teicoplanin, a glucopeptide antibiotic, was produced by a mutant of Actinoplanes teicomyceticus at 300 mg l-1 using mannose and yeast extract as carbon and nitrogen sources in flask culture and at 500 mg l-1 in 5-l jar fermenter. Teicoplanin production was 25-fold higher than in the parent strain.
- Subjects
ANTIBIOTICS; LEAVENING agents; YEAST; CARBON; NITROGEN; MANNOSE
- Publication
Biotechnology Letters, 2003, Vol 25, Issue 7, p537
- ISSN
0141-5492
- Publication type
Academic Journal
- DOI
10.1023/A:1022842203917