Title: Tetraalkylammonium Derivatives of 6-Methyluracil, a New Class of Cholinesterase Inhibitors: Characteristics of Interaction with Cholinesterases from Different Groups of Animals.
Authors: Anikienko, K. A.; Bychikhin, E. A.; Kurochkin, V. K.; Reznik, V. S.; Akamsin, V. D.; Galyametdinova, I. V.
Abstract: Presents a study which examined the synthesized tetraalklylammonium derivatives of 6-methyluracil for anticholinesterase activity. Efficiency of the inhibition of angiotensin converting enzyme (ACE) by tetraalklyammonium compounds; Trend toward a further decrease in the activity of ACE during dialysis; Effect of the structural difference between the enzymes from different groups of animals on the strength of binding of the inhibitors studied.
Subjects: ANGIOTENSIN converting enzyme; AMMONIUM compounds; URACIL; HETEROCYCLIC compounds; CHOLINESTERASES; CHOLINESTERASE inhibitors; ENZYMES
Publication: Doklady Biochemistry & Biophysics, 2001, Vol 376, Issue 1-6, p39
ISSN: 1607-6729
Publication type: Academic Journal
DOI: 10.1023/A:1018804227232

Tetraalkylammonium Derivatives of 6-Methyluracil, a New Class of Cholinesterase Inhibitors: Characteristics of Interaction with Cholinesterases from Different Groups of Animals.

Anikienko, K. A.; Bychikhin, E. A.; Kurochkin, V. K.; Reznik, V. S.; Akamsin, V. D.; Galyametdinova, I. V.