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Title

Canadian Consensus Guidelines for the Diagnosis and Treatment of Autoimmune Encephalitis in Adults.

Authors

Hahn, Christopher; Budhram, Adrian; Alikhani, Katayoun; AlOhaly, Nasser; Beecher, Grayson; Blevins, Gregg; Brooks, John; Carruthers, Robert; Comtois, Jacynthe; Cowan, Juthaporn; de Robles, Paula; Hébert, Julien; Kapadia, Ronak K.; Lapointe, Sarah; Mackie, Aaron; Mason, Warren; McLane, Brienne; Muccilli, Alexandra; Poliakov, Ilia; Smyth, Penelope

Abstract

Autoimmune encephalitis is increasingly recognized as a neurologic cause of acute mental status changes with similar prevalence to infectious encephalitis. Despite rising awareness, approaches to diagnosis remain inconsistent and evidence for optimal treatment is limited. The following Canadian guidelines represent a consensus and evidence (where available) based approach to both the diagnosis and treatment of adult patients with autoimmune encephalitis. The guidelines were developed using a modified RAND process and included input from specialists in autoimmune neurology, neuropsychiatry and infectious diseases. These guidelines are targeted at front line clinicians and were created to provide a pragmatic and practical approach to managing such patients in the acute setting.

Subjects

ENCEPHALITIS; COMMUNICABLE diseases; ADULTS; NEUROPSYCHIATRY; NEUROLOGY

Publication

Canadian Journal of Neurological Sciences, 2024, Vol 51, Issue 6, p734

ISSN

0317-1671

Publication type

Academic Journal

DOI

10.1017/cjn.2024.16

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