This article discusses a case study of a 23-year-old female patient with Hughes Syndrome, a disorder characterized by recurrent arterial or venous thrombosis and positive antiphospholipid antibodies. The patient presented with sudden right hemiparesis, and imaging tests revealed an organized thrombus in the left common carotid artery, causing severe stenosis. The patient was treated with warfarin and showed no relapse at the one-year follow-up. The article highlights the importance of oral anticoagulation and the expanded clinical scope of Hughes Syndrome. It also discusses the differential diagnosis and treatment options for organized thrombosis in the carotid artery.