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- Title
A Prospective Post-Marketing Observational Study of Brivaracetam in People With Focal Epilepsy.
- Authors
Yanes, Rayan; Briard, Joel Neves; Nguyen, Tang-Duc Jeremy; Sultanem, Maya; Nguyen, Dang Khoa; Gibbs, Steve; Ikeda, Kristin; Jirsch, Jeffrey; Josephson, Colin; Boisse Lomax, Lysa; Cloutier, Véronique; Keezer, Mark
- Abstract
We evaluated the effectiveness and tolerability of brivaracetam (BRV), an adjunctive antiseizure medication, as a treatment for focal epilepsy in adults. In this prospective study, we enrolled 51 participants from 3 sites across Canada. At 6 months, 68% (26/38) of participants were still taking BRV, among whom 35% (8/23) attained seizure freedom and 48% (11/23) saw their seizure frequency reduced by over 50%. We did not measure any significant change in irritability, quality of life, depression, and anxiety while treated with BRV. Our findings suggest BRV is effective in reducing seizure frequency among adults with focal epilepsy.
- Subjects
PARTIAL epilepsy; PEOPLE with epilepsy; QUALITY of life; SEIZURES (Medicine); ANXIETY
- Publication
Canadian Journal of Neurological Sciences, 2024, Vol 51, Issue 6, p860
- ISSN
0317-1671
- Publication type
Academic Journal
- DOI
10.1017/cjn.2023.328