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Title

Association Between Stroke Severity and Serum Troponin in Acute Stroke.

Authors

Kuczynski, Andrea M.; Rzyczniak, Grace; Cheong, Gee Hung Leo; Famiyeh, Petra; Vyas, Manav V.

Abstract

Serum troponin is often elevated in patients with acute stroke and its mechanism is unknown. In a retrospective single-center cohort study, we evaluated the association between stroke severity and serum troponin in 187 patients with acute stroke using multivariable modified Poisson models. A one-point increase in the National Institutes of Health Stroke Scale (measure of stroke severity) was associated with a marginally higher serum troponin level in adjusted models (aIRR 1.03; 1.01–1.05, P = 0.001). The modest, yet potentially independent, association between stroke severity and serum troponins could suggest a neurogenic basis for a cardiac injury in patients with acute stroke.

Subjects

STROKE; HEART injuries; TROPONIN; STROKE patients; CARDIAC patients

Publication

Canadian Journal of Neurological Sciences, 2024, Vol 51, Issue 6, p848

ISSN

0317-1671

Publication type

Academic Journal

DOI

10.1017/cjn.2023.323

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